Azathioprine combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Hospitalization 1/1/2004 40 Female 1/4/2006 Physician Slovenia
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2004 40 Female 12/28/2005
Primary
Secondary
Stillbirth Other Serious Female 2/1/2006 Physician Mexico
Primary
Concomitant
Urinary Tract Infection Death 46 Male 5/2/2006 Norway
Primary
Secondary
Tenosynovitis Other Serious 68 Female 5/1/2006 United States
Primary
Secondary
Tachypnoea Death 61 Female 5/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 67 Male 5/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liposarcoma Other Serious 5/9/2002 73 Male 5/12/2006 United States
Primary
Concomitant
Urine Protein/creatinine Ratio Increased Other Serious Male 6/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Protein/creatinine Ratio Increased Other Serious Male 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Skin Disorder Other Serious 42 Female 7/5/2006 Japan
Primary
Concomitant
Vitreous Opacities Other Serious 3/1/2002 57 Female 7/11/2006 Other Health Professional Germany
Primary
Secondary
Thrombocytopenia Life Threatening 12/1/2000 Female 8/14/2006
Primary
Secondary
Concomitant
Hyperaesthesia Other Serious 5/1/2004 57 Female 9/6/2006 Physician Germany
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 9/1/2005 60 Male 9/29/2006
Primary
Secondary
Pulmonary Alveolar Haemorrhage Other Serious 9/1/2005 60 Male 10/13/2006
Primary
Secondary
Lymphoproliferative Disorder Other Serious 28 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 34 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 30 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 38 Unknown 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Other Serious 19 Male 10/10/2006 Physician Japan
Primary
Concomitant
Lymphoproliferative Disorder Hospitalization 22 Male 10/10/2006 Physician Japan
Primary
Concomitant
Peptic Ulcer Death 53 Male 10/6/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 53 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 22 Male 10/30/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 10/26/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 34 Male 10/31/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 30 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer Hospitalization 38 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 19 Male 10/31/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Ulcer 28 Male 10/31/2006 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 6/21/2004 60 Male 187 lb 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Vena Cava Thrombosis Life Threatening 55 Male 12/13/2006 Other Health Professional France
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 55 Male 1/5/2007 France
Primary
Concomitant
Wegener's Granulomatosis Life Threatening 62 Female 5/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 121 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Hospitalization 11/14/2005 Male 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2007 57 Female 6/5/2007 Physician United Kingdom
Primary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 6/15/2007 Physician Greece
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2007 57 Female 7/6/2007 Physician United Kingdom
Primary
Concomitant
Parvovirus Infection Other Serious 7 Female 7/12/2007 Consumer United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 7 Female 7/14/2007 Physician Greece
Primary
Secondary
Tracheobronchitis Other Serious 1/1/2007 57 Female 7/17/2007 Physician United Kingdom
Primary
Concomitant
Parvovirus Infection Death 7 Female 55 lb 7/23/2007 Physician Greece
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 11/24/2006 23 Male 141 lb 7/24/2007 Consumer United States
Primary
Secondary
Concomitant
Central Nervous System Lymphoma Death 42 Female 7/8/2007 Physician United States
Primary
Concomitant
Renal Failure Other Serious 40 Female 8/7/2007 Physician Germany
Primary
Secondary
Hyperglycaemia Hospitalization 8/11/2007 Female 8/27/2007 Physician United States
Primary
Secondary
Concomitant
Polyuria Hospitalization 8/11/2007 Female 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/11/2007 Female 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 9/20/2007 Physician Greece
Primary
Secondary
Drug Ineffective Life Threatening 46 Male 10/2/2007 Physician Czech Republic
Primary
Concomitant
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
White Blood Cell Count Decreased Death 11/15/2006 7 Female 10/13/2007 Greece
Primary
Secondary
Immunosuppression Other Serious 4/19/2007 7 Female 10/16/2007 Consumer Greece
Primary
Secondary
Concomitant
Immunosuppression Other Serious 11/15/2006 7 Female 55 lb 10/19/2007 Consumer Greece
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 35 Female 10/22/2007 Physician United States
Primary
Concomitant
Parvovirus Infection Death 10/15/2006 7 Female 55 lb 10/23/2007 Physician Greece
Primary
Secondary
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/23/2007 Physician United States
Primary
Secondary
Muscular Weakness Hospitalization 58 Female 10/23/2007
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 35 Female 10/23/2007 Physician United States
Primary
Concomitant
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 10/25/2007 Other Health Professional Greece
Primary
Secondary
Histiocytosis Haematophagic Other Serious 4/3/2007 7 Female 55 lb 10/31/2007 Consumer Greece
Primary
Secondary
Concomitant
Parvovirus Infection Death 1/1/2007 7 Female 55 lb 10/27/2007 Physician Greece
Primary
Secondary
Tracheitis Hospitalization 9/30/2007 16 Female 132 lb 11/12/2007 Physician Argentina
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious Female 11/26/2007 Other Health Professional United States
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 33 Female 11/21/2007 Other Health Professional United States
Primary
Secondary
Refusal Of Treatment By Patient Other Serious 1/1/1997 33 Female 11/21/2007 Consumer United States
Primary
Secondary
Thrombotic Microangiopathy Other Serious 23 Female 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 48 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/6/2007 Other Health Professional Japan
Primary
Secondary
Lip And/or Oral Cavity Cancer Death 1/1/1998 33 Female 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2007 57 Female 12/7/2007 Physician United Kingdom
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 48 Male 12/13/2007 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 46 Male 12/14/2007 Other Health Professional Japan
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 12/20/2007 Physician Argentina
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 132 lb 1/11/2008 Physician Argentina
Primary
Secondary
Concomitant
Skin Hypertrophy Hospitalization 12/1/1995 64 Male 1/17/2008
Primary
Secondary
Wegener's Granulomatosis Hospitalization 1/3/2008 Male 1/22/2008 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious Female 1/23/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 5/1/2005 Female 1/29/2008 Spain
Primary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/4/2008 Physician Argentina
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 11/15/2006 7 Female 2/13/2008 Greece
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 2/15/2008 Physician Argentina
Primary
Secondary
Concomitant
Colon Cancer Metastatic Other Serious 6/19/2006 Female 116 lb 2/22/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2008 61 Female 169 lb 2/25/2008 France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/10/2008 12 3/4/2008 Physician United Kingdom
Primary
Concomitant
Metastases To Lymph Nodes Other Serious 6/19/2006 Female 116 lb 3/5/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 3/7/2008 Consumer United Kingdom
Primary
Concomitant
Congenital Osteodystrophy Other Serious Female 3/7/2008 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 2/10/2008 12 Male 3/11/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Death 45 Female 3/6/2008 Physician United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 3/13/2008 United Kingdom
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 3/20/2008 Physician Argentina
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/10/2008 12 Male 3/21/2008 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 45 Female 3/21/2008 United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 3/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 3/20/2008 United Kingdom
Primary
Secondary
Thrombotic Microangiopathy Other Serious 12 Male 3/27/2008 Japan
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 1/3/2008 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 16 Female 128 lb 3/28/2008 Physician Argentina
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Female 3/28/2008 United Kingdom
Primary
Secondary
Weight Decreased Death 45 Female 3/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Pyrexia Life Threatening 2/10/2008 12 Male 4/4/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 45 Female 4/4/2008 United Kingdom
Primary
Secondary
Thrombotic Microangiopathy Other Serious 12 Male 4/7/2008 Japan
Primary
Concomitant
Pyrexia Life Threatening 2/10/2008 12 Male 4/10/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Death 45 Female 4/4/2008 United Kingdom
Primary
Secondary
Skin Reaction Death Male 4/14/2008
Primary
Secondary
Concomitant
Skin Reaction Death Male 4/14/2008
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/1/2006 Female 4/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Female 4/24/2008 United Kingdom
Primary
Secondary
Concomitant
Polyuria Hospitalization 5/1/2007 Female 4/25/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/1999 45 Female 5/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Death 45 Female 4/28/2008 United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 21 Female 5/7/2008
Primary
Concomitant
Pyrexia Other Serious 5 Female 5/13/2008
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 5/23/2008 Physician Argentina
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 57 Female 5/30/2008 Other Health Professional Singapore
Primary
Secondary
Systemic Lupus Erythematosus Hospitalization 9/30/2007 Female 106 lb 5/30/2008 Physician Argentina
Primary
Secondary
Concomitant
Transaminases Increased Death 57 Female 5/26/2008 Physician Singapore
Primary
Secondary
Transaminases Increased Death 57 Female 5/30/2008 Japan
Primary
Secondary
Parvovirus Infection Death 5/2/2007 7 Female 55 lb 6/9/2008 Greece
Primary
Secondary
Parvovirus Infection Death 11/15/2006 7 Female 55 lb 6/17/2008 United States
Primary
Secondary
Transaminases Increased Death 57 Female 6/18/2008 Physician Singapore
Primary
Secondary
Concomitant
Scleroderma Other Serious 8/6/2003 68 Female 6/30/2008 Other Health Professional Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 8/1/2003 Female 132 lb 7/31/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 7/4/2008 68 Female 8/5/2008 Other Health Professional France
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 32 Male 8/5/2008 Other Health Professional United States
Primary
Secondary
Respiratory Failure Other Serious 1/1/1999 45 Female 8/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Female 8/14/2008 United Kingdom
Primary
Secondary
Concomitant
Stomatitis Death 44 Male 8/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2006 Female 8/20/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 27 Female 9/12/2008 Other Health Professional Italy
Primary
Secondary
Concomitant
Microcytic Anaemia Other Serious 1/1/2003 65 Female 9/16/2008
Primary
Concomitant
Liposarcoma Other Serious 5/9/2002 73 Male 9/17/2008 United States
Primary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 154 lb 9/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 8/1/2003 Female 132 lb 10/6/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2006 Female 10/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Disability 5/7/2008 80 Female 10/6/2008 United Kingdom
Primary
Secondary
Concomitant
Large Intestinal Ulcer Other Serious 3/1/2006 56 Female 10/15/2008
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 4/1/2006 Female 10/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 7/4/2008 68 Female 10/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 21 Male 10/17/2008 United Kingdom
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 59 Female 10/27/2008
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 45 Female 99 lb 10/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 45 Female 101 lb 10/28/2008 United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8/1/2004 39 Male 10/31/2008 Physician United Kingdom
Primary
Secondary
Rebound Effect Other Serious 5/1/2004 42 Male 11/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Ulcerative Keratitis Other Serious 1/1/2004 39 Male 10/27/2008 United Kingdom
Primary
Secondary

Drug Data