Avelox combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Other Serious 11/17/2005 89 Female 1/5/2006 Physician United States
Primary
Secondary
Thrombosis Hospitalization 1/31/2003 56 Male 287 lb 1/17/2006 Physician United States
Primary
Concomitant
Pain Hospitalization 72 Female 173 lb 1/12/2006 United States
Primary
Concomitant
Swelling Hospitalization 72 Female 173 lb 1/31/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2005 57 Female 286 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 8/1/2005 72 Female 173 lb 2/20/2006 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2005 72 Female 173 lb 2/28/2006 United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/30/2003 77 Female 134 lb 4/11/2006 Physician United States
Primary
Concomitant
Tendonitis Other Serious 1/25/2006 72 Female 4/4/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 1/31/2003 56 Male 287 lb 4/17/2006 Physician United States
Primary
Concomitant
Pneumonia Other Serious 4/1/2006 57 Female 200 lb 4/21/2006 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 4/23/2006 88 Male 166 lb 4/27/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Life Threatening 4/12/2006 71 Female 271 lb 5/26/2006 Canada
Primary
Concomitant
Renal Failure Acute Other Serious Male 6/6/2006 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 12/1/2005 Male 5/30/2006 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Rate Decreased Hospitalization 3/1/2006 Male 239 lb 6/26/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/27/2005 75 Female 160 lb 6/20/2006 Canada
Primary
Secondary
Concomitant
Sinusitis Other Serious 7/27/2000 79 Female 7/3/2006 Physician Germany
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Other Serious 8/22/2000 79 Female 7/3/2006 Physician United States
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 7/1/2006 Male 8/2/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/1/2006 Physician Germany
Primary
Interacting
Gastrointestinal Haemorrhage Other Serious 8/1/2006 Other Health Professional Germany
Primary
Secondary
Pancreatitis Other Serious 11/17/2005 89 Female 8/1/2006 Physician Germany
Primary
Secondary
Renal Failure Acute Other Serious Male 8/9/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2006 73 Male 251 lb 8/17/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization Female 7/11/2006 Physician United States
Primary
Secondary
Weight Decreased Other Serious 9/3/2004 53 Female 260 lb 7/11/2006 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 8/1/2005 62 Male 7/11/2006 Physician United States
Primary
Concomitant
Rash Generalised Other Serious Male 7/11/2006 Physician United States
Primary
Concomitant
Urticaria Other Serious 3/28/2005 61 Female 158 lb 7/11/2006 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 5/1/2006 72 Male 9/5/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/1/2006 73 Male 251 lb 9/11/2006 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 9/26/2006 Physician United States
Primary
Secondary
Rash Generalised Other Serious 5/1/2006 72 Male 9/29/2006 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 23 Male 141 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 23 Male 141 lb 12/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 4/12/2006 72 Female 271 lb 1/26/2007 Physician Canada
Primary
Concomitant
Hypoglycaemia Life Threatening 4/12/2006 72 Female 271 lb 1/29/2007 Physician Canada
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 7/25/2006 84 Female 126 lb 1/29/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/1/2005 Male 1/22/2007 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/1/2005 79 Male 2/7/2007 Consumer United States
Primary
Concomitant
Interacting
Shock Haemorrhagic Other Serious 12/7/2006 69 Female 3/28/2007 Physician United States
Primary
Concomitant
Shock Other Serious 12/7/2006 69 Female 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Infusion Site Extravasation Other Serious 3/15/2007 70 Female 5/1/2007 Pharmacist Canada
Primary
Concomitant
Rash Other Serious 86 Female 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 8/7/2006 68 Female 9/28/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/18/2006 74 Male 8/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 86 Female 8/14/2007 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/25/2007 Physician United States
Primary
Secondary
Weight Decreased Other Serious 9/3/2004 53 Female 260 lb 7/25/2007 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 12/16/2006 70 Male 7/25/2007 Physician United States
Primary
Concomitant
Urticaria Life Threatening 1/9/2007 77 Male 7/25/2007 Physician United States
Primary
Concomitant
Torsade De Pointes Life Threatening 10/22/2007 78 Female 11/14/2007 Physician Italy
Primary
Concomitant
Prothrombin Time Prolonged Life Threatening 4/18/2007 81 Female 12/4/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious Male 12/19/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 1/2/2008 Physician United States
Primary
Secondary
International Normalised Ratio Increased Other Serious 1/29/2008 Physician United States
Primary
Concomitant
Death Death 71 Male 2/11/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/22/2007 78 Female 2/14/2008 Other Health Professional Italy
Primary
Concomitant
Pneumonia Hospitalization 12/31/2007 Male 2/13/2008 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/9/2008 81 Female 3/4/2008 Physician United States
Primary
Concomitant
Haematoma Other Serious Female 3/6/2008 Physician United States
Primary
Secondary
Haematoma Other Serious Female 3/12/2008 Physician Germany
Primary
Secondary
International Normalised Ratio Increased Death 4/7/2008 Physician United States
Primary
Secondary
Hepatotoxicity Other Serious 4/10/2008 Pharmacist United States
Primary
Concomitant
Lung Infiltration Hospitalization 12/16/2005 Male 4/16/2008 Consumer United States
Primary
Secondary
Sinus Disorder Hospitalization 1/1/1998 Male 4/16/2008 Other Health Professional United States
Primary
Secondary
International Normalised Ratio Increased 4/25/2008 Physician United States
Primary
Secondary
Oedema Peripheral Other Serious 5/7/2008 84 Female 5/16/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2005 70 Female 130 lb 5/26/2008 Other Health Professional United States
Primary
Secondary
Death Death 71 Male 5/27/2008 Physician United States
Primary
Concomitant
Haematoma Other Serious Female 5/27/2008 Physician United States
Primary
Secondary
Vomiting Hospitalization 1/1/2005 70 Female 130 lb 5/27/2008 Other Health Professional United States
Primary
Secondary
Malaise Other Serious 5/1/2008 55 Female 5/28/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 12/2/2007 76 Female 5/28/2008 Physician United States
Primary
Concomitant
Haematoma Other Serious Female 5/30/2008 Physician Germany
Primary
Secondary
International Normalised Ratio Increased Death Female 6/12/2008 Physician United States
Primary
Secondary
International Normalised Ratio Increased Hospitalization 5/12/2008 83 Male 174 lb 6/20/2008 Pharmacist United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/7/2008 84 Female 7/1/2008 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 5/1/2008 55 Female 7/29/2008 Physician Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased 8/7/2008 Pharmacist United States
Primary
Concomitant
Coagulopathy 8/8/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 70 Female 130 lb 8/8/2008 Other Health Professional United States
Primary
Secondary
Hepatotoxicity Other Serious 8/8/2008 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 8/21/2008 Consumer United States
Primary
Concomitant
Dizziness Other Serious 8/25/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 9/8/2008 Physician United States
Primary
Concomitant
Dizziness Other Serious 9/15/2008 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 6/6/2008 90 Female 115 lb 9/10/2008 Physician United States
Primary
Secondary
Concomitant
Coagulopathy 9/23/2008 Physician United States
Primary
Concomitant
Heart Rate Decreased 10/25/2007 Physician United States
Primary
Concomitant
Malaise Other Serious 5/1/2008 55 Female 9/26/2008 Physician United States
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/2/2002 83 Male 11/15/2002 Pharmacist United States
Primary
Concomitant
Skin Wrinkling Other Serious 8/1/2006 77 Male 10/6/2008 Lawyer United States
Primary
Secondary
Concomitant
Skin Wrinkling Other Serious 8/1/2006 77 Male 10/10/2008 Lawyer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 10/24/2008 Male 189 lb 10/27/2008 Physician United States
Primary
Concomitant
Coagulopathy 11/6/2008 Physician United States
Primary
Concomitant
Death Death 11/3/2008 Male 184 lb 11/10/2008 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/7/2008 84 Female 6/25/2008 Consumer United States
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 4/1/2007 Female 11/18/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 9/19/2008 Male 201 lb 11/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 11/3/2008 Male 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 79 Female 136 lb 11/25/2008 United States
Primary
Concomitant
Coagulopathy 10/15/2008 Physician United States
Primary
Concomitant
Death Death Male 225 lb 12/23/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 9/19/2008 Male 201 lb 12/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death Male 225 lb 1/6/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 12/2/2008 Male 128 lb 1/15/2009 Pharmacist United States
Primary
Secondary
Adverse Drug Reaction Other Serious 1/28/2009 Physician United States
Primary
Interacting
Drug Interaction Other Serious 1/30/2009 Physician Germany
Primary
Interacting
International Normalised Ratio Increased Hospitalization 2/6/2009 Physician United States
Primary
Interacting
Death Death 11/3/2008 Male 184 lb 2/9/2009 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/11/2009 Physician Germany
Primary
Interacting
Death Death 11/3/2008 Male 184 lb 3/9/2009 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 2/10/2009 41 Female 400 lb 3/24/2009 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/23/2009 76 Female 4/20/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/4/2009 Physician United States
Primary
Interacting
Unevaluable Event Other Serious 3/1/2009 66 Male 5/8/2009 Other Health Professional United States
Primary
Concomitant
Urinary Incontinence Other Serious 12/29/2008 75 Male 6/8/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Unevaluable Event Other Serious 3/1/2009 66 Male 7/20/2009 Other Health Professional United States
Primary
Concomitant
Visual Impairment Hospitalization 10/25/2007 73 Male 229 lb 7/15/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Skin Induration Other Serious 9/1/2007 56 Male 209 lb 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 71 Male 8/3/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 65 Male 8/6/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 10/1/2007 Female 134 lb 9/1/2009 Lawyer United States
Primary
Secondary
Concomitant
Wound Hospitalization 71 Male 8/28/2009 United States
Primary
Concomitant
Unevaluable Event Death Male 8/31/2009 United States
Primary
Concomitant
Lactic Acidosis Hospitalization 3/1/2009 80 Female 9/10/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 65 Male 9/9/2009 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/21/2007 78 Female 9/11/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 78 Female 9/17/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 142 lb 9/23/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 68 Male 229 lb 9/24/2009 United States
Primary
Concomitant
Skin Induration Other Serious 3/1/2005 53 Male 209 lb 10/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 3/1/2005 53 Male 209 lb 10/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Hospitalization 71 Male 142 lb 10/10/2009 United States
Primary
Concomitant
Pruritus 3/29/2008 64 Male 3/25/2009 Physician United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/14/2008 60 Female 10/20/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/22/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 10/1/2007 Female 134 lb 10/29/2009 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 142 lb 10/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/21/2007 79 Female 10/26/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/4/2009 United States
Primary
Concomitant

Drug Data