Avastin combined with Pemetrexed

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diverticulitis Other Serious 58 Male 10/2/2006 Physician United States
Primary
Secondary
Respiratory Arrest Hospitalization 5/6/2008 Male 118 lb 5/21/2008 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 5/6/2008 Male 147 lb 5/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Other Serious Female 132 lb 6/5/2008 Physician United Kingdom
Primary
Secondary
Unevaluable Event Other Serious 3/1/2008 Female 132 lb 7/3/2008 Physician United Kingdom
Primary
Secondary
Diverticulitis Hospitalization 2/23/2006 Female 135 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/6/2006 Female 119 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/27/2006 Female 119 lb 7/17/2008 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/28/2006 Female 160 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 5/6/2008 Male 118 lb 8/1/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/19/2008 Male 194 lb 10/9/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/28/2008 Female 10/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/19/2008 Male 194 lb 10/15/2008 Physician United States
Primary
Secondary
Concomitant
Death Hospitalization 9/1/2008 Male 10/15/2008 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 64 Female 11/26/2008 Physician Greece
Primary
Concomitant
Diplopia Other Serious 70 Male 11/26/2008 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/19/2008 Male 194 lb 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/1/2008 Male 12/19/2008 Physician United States
Primary
Secondary
Concomitant
Bronchospasm Other Serious 1/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Other Serious 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Anaemia Other Serious 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Diplopia Other Serious 70 Male 1/8/2009 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/19/2008 Male 194 lb 2/6/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/9/2009 Male 3/2/2009 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 2/9/2009 Male 3/4/2009 Physician United States
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 3/11/2009 Female 107 lb 3/16/2009 Other Health Professional United States
Primary
Secondary
Pancytopenia Hospitalization 2/9/2009 Male 4/8/2009 Physician United States
Primary
Concomitant
Nausea Hospitalization 4/11/2009 Male 182 lb 4/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Aneurysm Ruptured Hospitalization 4/22/2009 Male 178 lb 5/13/2009 Physician United States
Primary
Secondary
Sepsis Life Threatening 4/29/2009 Male 5/15/2009 Physician United States
Primary
Concomitant
Multi-organ Failure Death 4/24/2009 Male 214 lb 5/22/2009 Physician Germany
Primary
Concomitant
Sepsis Life Threatening 4/29/2009 Male 6/3/2009 Physician United States
Primary
Concomitant
Superior Vena Caval Occlusion Other Serious Female 6/17/2009 Physician Germany
Primary
Concomitant
Superior Vena Caval Occlusion Other Serious Female 6/25/2009 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 70 Male 216 lb 6/10/2009 United States
Primary
Secondary
Concomitant
Aneurysm Ruptured Hospitalization 4/22/2009 Male 178 lb 9/14/2009 Physician United States
Primary
Secondary
Odynophagia Hospitalization 10/26/2008 Male 154 lb 10/8/2009 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 10/15/2009 Male 149 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 11/9/2009 Male 153 lb 11/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 6/27/2008 41 Female 126 lb 2/5/2010 Physician Portugal
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/11/2010 Female 104 lb 2/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 6/27/2008 41 Female 2/16/2010 Portugal
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/12/2010 Male 178 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/28/2009 46 Male 3/9/2010 Other Health Professional Japan
Primary
Secondary
Rib Fracture Hospitalization 2/13/2010 Male 202 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 2/26/2010 Female 95 lb 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/28/2009 46 Male 3/12/2010 Physician Japan
Primary
Secondary
Non-small Cell Lung Cancer Stage Iv Death 3/19/2010 52 Female 101 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 12/28/2009 46 Male 4/6/2010 Other Health Professional Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 46 Male 4/16/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Other Serious 12/28/2009 46 Male 4/16/2010 Physician Japan
Primary
Secondary
Oedema Peripheral Other Serious 2/21/2010 72 Male 4/27/2010 Physician China
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/21/2010 62 Male 164 lb 5/12/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Life Threatening 4/21/2010 62 Male 171 lb 5/21/2010 Physician Japan
Primary
Concomitant
Aortic Dissection Life Threatening 4/21/2010 62 Male 171 lb 6/21/2010 Physician Japan
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/13/2010 68 Female 176 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 9/7/2010 Physician Brazil
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious Female 9/14/2010 Physician Brazil
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 9/17/2010 68 Female 174 lb 9/21/2010 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 12/1/2010 63 Female 141 lb 2/18/2011 Physician Switzerland
Primary
Concomitant
Rebound Effect Death 6/28/2010 58 Male 168 lb 2/22/2011 Consumer Switzerland
Primary
Concomitant
Hypoxia Hospitalization 69 Male 3/3/2011 Physician France
Primary
Concomitant
Device Related Infection Death 1/30/2011 60 Female 3/18/2011 Other Health Professional France
Primary
Secondary
Pulmonary Haemorrhage Death Male 4/13/2011 Consumer United States
Primary
Concomitant
Intestinal Ischaemia Death 2/12/2010 59 Male 152 lb 5/9/2011 Other Health Professional France
Primary
Secondary
Concomitant
Antibiotic Resistant Staphylococcus Test Positive Hospitalization 3/1/2011 47 Female 111 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 2/16/2011 66 Female 5/11/2011 Physician Switzerland
Primary
Secondary
Concomitant
Death Death 4/23/2011 67 Female 5/11/2011 Physician Germany
Primary
Secondary
Hypokalaemia Hospitalization 4/16/2011 60 Female 176 lb 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 6/25/2010 64 Male 6/2/2011 Physician United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 8/4/2010 71 Male 8/1/2011 Physician Japan
Primary
Secondary
Febrile Neutropenia Hospitalization 1/1/2010 70 Male 8/26/2011 Physician Japan
Primary
Secondary
Microangiopathic Haemolytic Anaemia Hospitalization 8/3/2010 57 Male 222 lb 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Feeding Tube Complication Hospitalization 7/11/2011 52 Male 8/30/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/31/2011 Other Health Professional United States
Primary
Secondary
Fatigue Hospitalization 7/11/2011 52 Male 8/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 10/21/2011 Physician Netherlands
Primary
Secondary
Fall Hospitalization 7/1/2011 10/27/2011 Physician United States
Primary
Secondary
Concomitant
Leukodystrophy Other Serious 11/1/2011 Physician United States
Primary
Secondary
Leukoencephalopathy Other Serious 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/9/2011 76 Male 161 lb 11/4/2011 Germany
Primary
Concomitant
Fall Death 7/1/2011 Female 11/7/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 11/10/2011 Physician United States
Primary
Secondary
Concomitant
Leukoencephalopathy Death Female 11/29/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 72 Male 11/30/2011 Physician Algeria
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 8/9/2011 55 Female 140 lb 12/8/2011 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/14/2011 63 Male 174 lb 12/23/2011 Germany
Primary
Concomitant
Intestinal Perforation Other Serious 10/27/2011 67 Male 152 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Intestinal Perforation Death 10/27/2011 67 Male 152 lb 1/4/2012 Physician Japan
Primary
Secondary
Concomitant
Aspiration Pleural Cavity Other Serious 67 Male 1/20/2012 Physician United States
Primary
Concomitant
Malaise Other Serious 2/18/2011 60 Male 132 lb 2/15/2012 Consumer France
Primary
Concomitant
Fatigue Other Serious 4/26/2007 52 Female 3/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Death 4/26/2007 52 Female 3/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Extremity Necrosis Other Serious 1/15/2012 55 Male 176 lb 3/16/2012 Other Health Professional New Zealand
Primary
Concomitant
Vomiting Hospitalization 1/16/2012 69 Male 3/21/2012 Physician Switzerland
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 2/4/2012 47 Male 150 lb 3/30/2012 France
Primary
Secondary
Concomitant
Lymphadenectomy Other Serious 55 4/12/2012 Consumer United States
Primary
Concomitant
Renal Tubular Disorder Hospitalization 2/7/2012 47 Male 4/18/2012 Physician France
Primary
Secondary
Cardiac Arrest Death 4/26/2012 73 Male 159 lb 5/8/2012 Physician Germany
Primary
Concomitant
Dysphagia Other Serious 6/1/2012 48 Female 106 lb 6/22/2012 Consumer Canada
Primary
Concomitant
Death Hospitalization 8/19/2010 69 Female 135 lb 7/3/2012 United States
Primary
Secondary
Concomitant
Disease Progression Death 4/16/2012 Female 7/6/2012 Physician France
Primary
Concomitant
Pain In Extremity Hospitalization 3/1/2012 61 Male 143 lb 7/30/2012 Physician Germany
Primary
Concomitant
Syncope Other Serious 7/27/2012 56 Female 104 lb 8/2/2012 Consumer Venezuela
Primary
Concomitant
Large Intestine Perforation Death 6/18/2012 69 Male 8/20/2012 Physician France
Primary
Concomitant
Pneumonia Aspiration Death 4/1/2012 Male 8/20/2012 Physician Japan
Primary
Secondary
Blood Test Abnormal Hospitalization 6/6/2012 66 Male 227 lb 8/13/2012 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 6/6/2012 66 Male 227 lb 8/14/2012 Physician United States
Primary
Secondary
Disease Progression Other Serious 8/27/2012 Physician Netherlands
Primary
Secondary
Urine Analysis Abnormal Death 12/7/2009 55 Female 170 lb 9/13/2012 Physician Us
Primary
Secondary
Concomitant
Procedural Complication Other Serious 8/19/2010 70 Female 135 lb 9/14/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 7/2011 Female 12/5/2012 Physician Us
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 10/27/2011 67 Male 152 lb 1/11/2013 Consumer Jp
Primary
Secondary
Concomitant
Off Label Use Death Female 12/16/2013 Consumer Us
Primary
Secondary
Concomitant
Disease Progression Death Male 11/22/2012 Physician Us
Primary
Secondary
Sepsis Death 3/2/2010 68 Female 134 lb 9/4/2012 Physician Us
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 11/15/2009 79 Female 176 lb 9/5/2012 Physician Us
Primary
Secondary
Concomitant
Hypothermia Hospitalization 4/24/2011 84 Male 148 lb 9/10/2012 Physician Us
Primary
Secondary
Concomitant
Wound Infection 46 Male Us
Primary
Secondary
Vision Blurred Hospitalization 12/2/2009 48 Female 123 lb 9/21/2013 Physician Ca
Primary
Secondary
Concomitant
Metastases To Prostate Death Male 9/25/2012 Physician Us
Primary
Concomitant
Sepsis Death Male 10/22/2012 Physician Us
Primary
Secondary
Concomitant
Vomiting Death Female 126 lb 12/17/2013 Physician Us
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 55 Female 11/5/2012 Physician Us
Primary
Concomitant
Skin Toxicity Death 11/28/2012 Physician De
Primary
Secondary
Disease Progression Other Serious 65 Female 12/11/2012 Other Health Professional Au
Primary
Secondary
Concomitant
Rash Life Threatening 10/22/2012 72 Female 97 lb 1/28/2013 Physician Jp
Primary
Secondary
Concomitant
Ischaemic Stroke Disability 7/2012 56 Female 12/26/2012 Physician Dz
Primary
Secondary
Toothache Death 10/27/2011 67 Male 152 lb 1/8/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 7/6/2012 Male 106 lb 1/29/2013 Physician Jp
Primary
Secondary
Concomitant
Myocardial Infarction Death 11/12/2012 50 Male 153 lb 1/30/2013 Pharmacist Us
Primary
Concomitant
Ulcer Other Serious 2/4/2013 Male 2/15/2013 Physician Jp
Primary
Concomitant
Ulcer Other Serious 2/4/2013 Male 2/15/2013 Physician Jp
Primary
Concomitant
Interstitial Lung Disease Other Serious Female 1/17/2013 Pharmacist Us
Primary
Secondary
Peritoneal Disorder Other Serious 5/10/2012 58 Male 3/1/2013 Other Health Professional Us
Primary
Secondary
Cardiac Arrest Death Female 161 lb 9/11/2012 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Death 40 Male 5/9/2013 Physician Dz
Primary
Secondary
Lung Adenocarcinoma Death 1/18/2013 63 Male 126 lb 8/5/2013 Physician Jp
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/17/2013 87 Male 200 lb 8/20/2013 Consumer Us
Primary
Concomitant
Haemoptysis Other Serious Female 6/27/2013 Consumer Cn
Primary
Concomitant
Phlebitis Other Serious 73 Female 99 lb 7/10/2013 Consumer Cn
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious NotSpecified 7/12/2013 Physician Cn
Primary
Concomitant
Weight Increased Other Serious 6/5/2013 62 Male 146 lb 8/27/2013 Physician Ca
Primary
Concomitant
Hypertensive Crisis Other Serious Female 148 lb 8/24/2013 Consumer Ve
Primary
Concomitant
Fatigue Death Female 98 lb 12/13/2013 Physician Us
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Other Serious 60 Female 10/26/2013 Physician Au
Primary
Concomitant
Weight Decreased Other Serious 2007 62 Male 190 lb 12/5/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data