Avastin combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Intestinal Perforation Hospitalization 12/4/2005 65 Male 182 lb 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/17/2005 48 Female 1/31/2006 Physician United States
Primary
Concomitant
Respiration Abnormal Required Intervention 11/23/2005 63 Female 359 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/30/2005 59 Female 3/28/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 4/4/2006 United States
Primary
Concomitant
Metastases To Central Nervous System Life Threatening 3/1/2006 57 Female 3/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Nuclear Magnetic Resonance Imaging Brain Abnormal Hospitalization 7/11/2004 41 Female 3/31/2006 Physician United States
Primary
Secondary
Troponin I Increased Life Threatening 2/15/2006 58 Female 142 lb 2/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Perianal Abscess Hospitalization 4/17/2006 46 Female 5/5/2006 Physician Finland
Primary
Secondary
Dermatitis Exfoliative Hospitalization 2/17/2006 55 Female 146 lb 5/12/2006 Physician Austria
Primary
Secondary
Neuropathy 65 Male 3/1/2006 Pharmacist United States
Primary
Concomitant
Wound Dehiscence Other Serious 48 Female 3/1/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 6/4/2006 United States
Primary
Concomitant
Perianal Abscess Hospitalization 4/17/2006 46 Female 6/5/2006 Physician Finland
Primary
Secondary
Septic Shock Death 7/13/2006 71 Male 171 lb 7/14/2006 Other Health Professional United States
Primary
Concomitant
Erythema Hospitalization 8/9/2006 71 Female 8/24/2006 Other Health Professional Finland
Primary
Secondary
Erythema Hospitalization 8/9/2006 71 Female 117 lb 8/30/2006 Other Health Professional Finland
Primary
Secondary
Vomiting Hospitalization 6/8/2006 59 Male 178 lb 6/8/2006 Other Health Professional United States
Primary
Concomitant
Drug Hypersensitivity Hospitalization 8/9/2006 71 Female 117 lb 9/13/2006 Other Health Professional Finland
Primary
Secondary
Wound Complication Required Intervention 7/17/2006 49 Unknown 9/18/2006 Physician United States
Primary
Secondary
Oesophagitis Other Serious 8/21/2006 55 Male 205 lb 9/26/2006 Other Health Professional United States
Primary
Secondary
Viral Oesophagitis Other Serious 6/14/2006 55 Male 205 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Pollakiuria Disability 8/31/2006 76 Female 147 lb 10/17/2006 Other Health Professional United States
Primary
Secondary
Viral Infection Hospitalization 9/21/2006 38 Female 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 42 Male 11/17/2006 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 11/21/2006 77 Male 171 lb 12/5/2006 United States
Primary
Secondary
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/19/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 10/18/2006 51 Male 1/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2006 68 Female 1/12/2007 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/21/2006 77 Male 171 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Required Intervention 12/24/2006 74 Male 172 lb 1/10/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 1/19/2007 41 Female 88 lb 2/26/2007 Physician France
Primary
Secondary
Concomitant
Sudden Death Hospitalization 3/1/2007 68 Female 146 lb 3/15/2007 Other Health Professional United States
Primary
Secondary
Mucosal Inflammation Hospitalization Female 3/27/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 2/28/2007 58 Female 147 lb 3/29/2007 United States
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 2/27/2007 Female 401 lb 4/11/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/27/2007 Female 182 lb 4/25/2007 Physician United States
Primary
Secondary
Concomitant
Disease Progression Female 2/28/2007 Pharmacist United States
Primary
Concomitant
Disease Progression 1/12/2006 48 Female 2/28/2007 Other Health Professional United States
Primary
Concomitant
Peripheral Sensory Neuropathy 75 Female 2/28/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/28/2007 Consumer United States
Primary
Concomitant
Vena Cava Thrombosis Required Intervention 50 Female 2/28/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 2/28/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/28/2007 78 Male 152 lb 7/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 7/10/2007 51 Female 7/31/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/28/2007 78 Male 152 lb 8/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Increased Hospitalization Female 170 lb 8/16/2007 Consumer United States
Primary
Concomitant
Ejection Fraction Decreased Life Threatening 7/10/2007 Female 8/16/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/28/2007 78 Male 152 lb 8/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Microangiopathy Hospitalization 8/23/2006 Female 146 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 8/16/2007 Female 173 lb 9/18/2007 Consumer United Kingdom
Primary
Secondary
Skin Exfoliation Disability 59 Female 9/10/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/20/2007 Female 10/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 6/19/2007 79 Female 177 lb 10/12/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Hospitalization 6/19/2007 79 Female 177 lb 10/25/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Death Female 10/29/2007 Consumer United States
Primary
Concomitant
Blood Pressure Increased Hospitalization Female 170 lb 11/8/2007 Consumer United States
Primary
Concomitant
Hypoxia Hospitalization 10/22/2007 Male 101 lb 11/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastases To Skin Other Serious Female 11/9/2007 Physician United Kingdom
Primary
Concomitant
Depression Hospitalization 8/23/2006 Female 146 lb 11/13/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/20/2007 Female 11/20/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonitis Life Threatening 9/26/2007 Female 100 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Throat Tightness Life Threatening 11/12/2007 51 Female 11/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 9/14/2007 Female 11/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/22/2007 Male 101 lb 11/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Impaired Healing Other Serious Female 11/30/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/22/2007 Male 101 lb 12/7/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death Female 12/11/2007 Consumer United States
Primary
Concomitant
Pneumonitis Life Threatening 9/26/2007 Female 100 lb 12/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 9/26/2007 Female 100 lb 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/21/2007 63 Female 1/26/2008 Other Health Professional Sweden
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/1/2008 45 Female 2/4/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 9/26/2007 Female 100 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/15/2008 Female 2/13/2008 Physician United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 8/21/2007 63 Female 2/13/2008 Other Health Professional Sweden
Primary
Concomitant
Portal Hypertension Other Serious Female 2/15/2008 Physician United Kingdom
Primary
Secondary
Urticaria Other Serious 1/29/2008 Female 144 lb 2/25/2008 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/3/2008 70 Female 3/5/2008 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious Female 161 lb 3/12/2008 Physician United Kingdom
Primary
Concomitant
Magnesium Deficiency Hospitalization 2/10/2008 70 Female 196 lb 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious Male 3/26/2008 Physician United States
Primary
Concomitant
Radiation Myelopathy Other Serious 1/28/2008 61 Female 4/10/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 2/19/2008 Female 4/10/2008 Physician United Kingdom
Primary
Concomitant
Nasal Septum Perforation Other Serious 2/1/2008 Female 118 lb 4/16/2008 Physician United Kingdom
Primary
Concomitant
Oesophageal Ulcer Hospitalization 2/25/2008 Female 118 lb 4/16/2008 Physician United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 1/15/2008 Female 4/17/2008 Physician United Kingdom
Primary
Concomitant
Herpes Simplex Hospitalization 3/3/2008 Female 192 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 11/14/2007 Female 4/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 2/28/2008 Consumer United States
Primary
Concomitant
Vena Cava Thrombosis Required Intervention 50 Female 2/28/2008 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 8/20/2007 Female 4/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 3/3/2008 Female 192 lb 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 4/2/2008 60 Male 5/7/2008 Pharmacist United States
Primary
Concomitant
Pyramidal Tract Syndrome Life Threatening 4/30/2008 Female 140 lb 5/9/2008 Consumer United States
Primary
Secondary
Concomitant
Radiation Myelopathy Other Serious 1/28/2008 Female 143 lb 6/3/2008 Physician United Kingdom
Primary
Concomitant
Brain Oedema Other Serious 6/4/2008 Consumer United States
Primary
Concomitant
Infarction Life Threatening 4/30/2008 Female 140 lb 6/4/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 5/26/2008 Male 152 lb 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Other Serious 1/29/2008 Female 6/20/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 60 Female 6/25/2008 Consumer United Kingdom
Primary
Concomitant
Nasal Septum Perforation Death 1/29/2008 Female 6/26/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinal Tear Other Serious 5/27/2008 Female 118 lb 6/26/2008 Consumer United States
Primary
Concomitant
Hypertensive Encephalopathy Other Serious 5/26/2008 Female 151 lb 7/3/2008 Consumer United States
Primary
Concomitant
Hypertension Other Serious 7/16/2007 60 Male 219 lb 11/6/2007 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious 7/12/2007 59 Female 11/6/2007 Other Health Professional United States
Primary
Concomitant
Phlebitis Hospitalization 60 Female 8/6/2008 Physician United Kingdom
Primary
Concomitant
Polyneuropathy Other Serious 10/1/2007 Female 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 7/1/2008 Female 8/8/2008 Pharmacist United Kingdom
Primary
Secondary
Erythema Hospitalization 7/17/2008 Female 8/13/2008 Physician United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 6/15/2008 Female 8/15/2008 Consumer United States
Primary
Concomitant
Metastases To Meninges Life Threatening 1/15/2008 Female 8/19/2008 Physician Finland
Primary
Concomitant
Pain Hospitalization 8/13/2008 49 Male 9/9/2008 Physician United States
Primary
Secondary
Leukoencephalopathy Hospitalization Female 9/19/2008 Consumer Slovakia (Slovak Republic)
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/7/2008 Female 9/23/2008 Physician United Kingdom
Primary
Concomitant
Hallucination Other Serious 6/11/2008 Male 159 lb 9/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 3/2/2008 Female 9/26/2008 Physician United Kingdom
Primary
Secondary
Death Death 5/10/2008 Female 10/2/2008 Consumer United Kingdom
Primary
Secondary
Small Intestinal Obstruction Hospitalization 1/2/2007 Male 135 lb 10/3/2008 Physician United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 53 Female 10/3/2008 Consumer Slovakia (Slovak Republic)
Primary
Concomitant
Portal Hypertension Other Serious Female 10/13/2008 Physician France
Primary
Concomitant
Breast Cancer Metastatic Death 5/10/2008 Female 10/14/2008 Consumer United Kingdom
Primary
Secondary
Tumour Marker Increased Other Serious 1/1/2008 47 Female 145 lb 9/19/2008 United States
Primary
Concomitant
Pain In Jaw Other Serious 4/2/2008 60 Male 9/26/2008 Pharmacist United States
Primary
Concomitant
Skin Disorder Other Serious 62 Female 10/28/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Hypertension Life Threatening 9/29/2008 Female 10/31/2008 Pharmacist United States
Primary
Secondary
Concomitant
Ascites Other Serious 58 Female 11/14/2008 Consumer United Kingdom
Primary
Secondary
Rectal Haemorrhage Hospitalization 71 Female 11/14/2008 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 71 Female 11/18/2008 United States
Primary
Concomitant
Tricuspid Valve Incompetence Life Threatening 9/26/2007 Female 100 lb 11/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 64 Female 11/26/2008 Physician Greece
Primary
Concomitant
Ascites Other Serious 58 Female 11/26/2008 Consumer United Kingdom
Primary
Secondary
Urticaria Other Serious 10/20/2008 Female 11/26/2008 Physician United Kingdom
Primary
Concomitant
Intestinal Ischaemia Other Serious 11/14/2008 40 Female 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Cardiomyopathy Hospitalization 11/4/2008 Female 12/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/25/2008 55 Female 12/5/2008 Physician United Kingdom
Primary
Concomitant
Tooth Loss Other Serious Female 12/8/2008 Consumer United States
Primary
Concomitant
Intestinal Ischaemia Other Serious 11/14/2008 40 Female 12/9/2008 United Kingdom
Primary
Secondary
Malaise Other Serious 11/14/2008 40 Female 12/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Hypokinesia Hospitalization 11/4/2008 Female 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 12/17/2008 Physician Germany
Primary
Concomitant
Interacting
Hepatitis Other Serious 69 Female 12/19/2008 Other Health Professional United States
Primary
Concomitant
Pain In Jaw Other Serious 4/2/2008 Male 12/19/2008 Pharmacist United States
Primary
Concomitant
Intestinal Ischaemia Other Serious 11/14/2008 40 Female 12/10/2008 United Kingdom
Primary
Secondary
Intestinal Obstruction Hospitalization 7/23/2008 64 Female 12/23/2008 Other Health Professional Greece
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/4/2008 Female 12/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 7/18/2008 Female 12/24/2008 Physician United Kingdom
Primary
Concomitant
Pulmonary Hypertension Life Threatening 9/29/2008 Female 12/31/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/15/2008 Female 1/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neurodegenerative Disorder Disability Female 1/27/2009 Other Health Professional France
Primary
Secondary

Drug Data