Avastin combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Disease Progression Death 8/30/2005 51 Male 110 lb 1/3/2006 Physician India
Primary
Concomitant
Cholinergic Syndrome Hospitalization 1/4/2006 33 Male 1/19/2006 Physician France
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 9/7/2005 57 Female 1/19/2006 Physician Australia
Primary
Secondary
Concomitant
Cholinergic Syndrome Hospitalization 1/4/2006 33 Male 159 lb 1/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Extravasation Hospitalization 12/12/2005 61 Male 176 lb 2/8/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 3/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/4/2006 33 Male 159 lb 3/10/2006 Physician France
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 9/7/2005 57 Female 3/21/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Gastritis Haemorrhagic Hospitalization 12/29/2005 41 Female 3/24/2006 Consumer Germany
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 10/8/2005 57 Female 4/6/2006 Physician Australia
Primary
Secondary
Concomitant
Troponin I Increased Hospitalization 10/8/2005 57 Female 4/10/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/4/2006 33 Male 159 lb 5/17/2006 Physician France
Primary
Secondary
Concomitant
Extravasation Hospitalization 12/12/2005 61 Male 176 lb 5/16/2006 Physician Australia
Primary
Secondary
Concomitant
Gastritis Haemorrhagic Hospitalization 12/29/2005 41 Female 6/5/2006 Consumer Germany
Primary
Secondary
Concomitant
Weight Decreased Death 5/8/2006 54 Male 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 5/8/2006 54 Male 6/13/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 5/8/2006 54 Male 143 lb 6/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/7/2006 67 Female 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/18/2006 68 7/14/2006 Physician United States
Primary
Secondary
Gastrointestinal Perforation Other Serious 5/5/2006 42 Male 5/31/2006 Pharmacist United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 5/5/2006 42 Male 5/31/2006 Pharmacist United States
Primary
Concomitant
Screaming Hospitalization 3/9/2006 55 Female 220 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Screaming Hospitalization 3/9/2006 55 Female 220 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Spinal Cord Compression Hospitalization 3/1/2006 78 Female 8/11/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/29/2006 52 Male 8/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 8/8/2006 62 Male 154 lb 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/8/2006 59 Male 178 lb 6/8/2006 Other Health Professional United States
Primary
Concomitant
Stomatitis Hospitalization 8/3/2006 55 Male 150 lb 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 5/12/2006 69 Male 155 lb 9/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/3/2006 55 Male 150 lb 10/19/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 8/3/2006 55 Male 150 lb 10/25/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 8/3/2006 55 Male 150 lb 11/9/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 8/3/2006 55 Male 150 lb 11/16/2006 Physician Japan
Primary
Secondary
Osteonecrosis Other Serious 4/1/2006 68 Female 12/12/2006 United States
Primary
Concomitant
Splenic Infarction Required Intervention 4/19/2006 Male 12/15/2006 Pharmacist United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 12/22/2006 Physician Australia
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2006 68 Female 1/12/2007 United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/12/2007 Physician Australia
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 10/29/2006 52 Female 123 lb 1/18/2007 Physician Australia
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/31/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/3/2007 53 Male 3/19/2007 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/2005 43 Female 243 lb 3/24/2007 France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/23/2007 51 Female 119 lb 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 3/3/2007 53 Male 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 2/6/2007 66 Male 4/16/2007 Other Health Professional United States
Primary
Concomitant
Septic Shock Hospitalization 3/31/2006 Male 4/20/2007 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Death 2/6/2007 66 Male 4/30/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/12/2007 59 Male 4/30/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/10/2007 67 Male 132 lb 5/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/31/2006 Male 5/14/2007 Physician United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1/3/2008 70 Female 3/5/2008 Consumer United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 1/31/2007 55 Male 2/28/2008 Other Health Professional United States
Primary
Concomitant
Sigmoiditis Hospitalization 2/1/2008 Male 5/29/2008 Consumer Sweden
Primary
Secondary
Concomitant
Sigmoiditis Hospitalization Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Torsade De Pointes Life Threatening 4/22/2008 Female 6/25/2008 Physician United Kingdom
Primary
Concomitant
Torsade De Pointes Life Threatening 4/22/2008 Female 8/13/2008 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 4/9/2008 Female 9/3/2008 Other Health Professional France
Primary
Concomitant
Torsade De Pointes Life Threatening 4/22/2008 Female 9/30/2008 Physician France
Primary
Concomitant
Torsade De Pointes Life Threatening 4/22/2008 Female 11/13/2008 Physician France
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2001 Female 147 lb 12/9/2008 United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 2/11/2009 Other Health Professional United States
Primary
Concomitant
Peritonitis Death 12/21/2008 Male 171 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Hospitalization 5/1/2008 Female 2/26/2009 Physician Germany
Primary
Concomitant
Interacting
Tooth Fracture Other Serious 1/1/2001 Female 147 lb 3/2/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 3/22/2009 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Migraine Death 2/18/2009 66 Female 4/1/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Swelling Hospitalization 5/1/2008 Female 4/2/2009 Physician Germany
Primary
Concomitant
Interacting
Diarrhoea Death 2/18/2009 66 Female 4/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Migraine Death 2/18/2009 66 Female 4/7/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Enteritis Death 2/1/2008 Female 4/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 2/7/2009 59 Male 194 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2009 Female 4/22/2009 Consumer Canada
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/1/2009 Female 4/24/2009 Consumer Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 4/20/2009 Female 4/28/2009 Consumer United States
Primary
Concomitant
Migraine Death 2/27/2009 66 Female 5/5/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Migraine Death 2/27/2009 66 Female 5/5/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Migraine Other Serious 2/18/2009 66 Female 5/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Migraine Other Serious 2/18/2009 66 Female 5/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Migraine Other Serious 2/18/2009 66 Female 5/12/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/1/2009 Female 5/13/2009 Consumer Canada
Primary
Secondary
Concomitant
Toothache Other Serious 1/1/2007 Male 172 lb 5/20/2009 Other Health Professional United States
Primary
Concomitant
Microangiopathic Haemolytic Anaemia Death 2/24/2009 44 6/4/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 6/9/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 6/15/2009 Male 170 lb 6/19/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 6/22/2009 Male 170 lb 6/23/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 70 Male 216 lb 6/10/2009 United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 1/1/2009 Male 8/25/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/2005 43 Female 9/11/2009 Consumer Germany
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/2005 43 Female 9/14/2009 Consumer Germany
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 9/22/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 10/2/2009 Female 241 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 1/1/2009 Male 10/21/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 11/4/2009 Other Health Professional United States
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Hospitalization 68 Female 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 181 lb 11/30/2009 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 1/12/2010 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
Urinary Retention Other Serious 1/11/2007 Male 1/22/2010 Physician United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 1/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Death 10/2/2009 Female 241 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Male 181 lb 1/29/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 2/15/2010 United States
Primary
Secondary
Concomitant
Tooth Impacted Other Serious 1/1/2005 Female 2/18/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 Male 172 lb 2/18/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 2/18/2010 Female 83 lb 2/25/2010 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/18/2010 Female 83 lb 3/1/2010 Physician Brazil
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/4/2010 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/11/2007 Male 3/15/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/18/2010 Female 83 lb 3/18/2010 Physician Brazil
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/11/2007 Male 3/18/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Radiotherapy Other Serious 1/1/2005 40 Male 4/6/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2006 44 Female 200 lb 4/20/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 4/19/2009 67 Male 430 lb 6/1/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2006 44 Female 200 lb 6/7/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/7/2010 United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/14/2010 United States
Primary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 7/16/2010 United States
Primary
Concomitant
Malignant Neoplasm Progression Death 3/19/2010 65 Male 7/19/2010 Other Health Professional Colombia
Primary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Disease Progression Death 6/28/2010 60 Male 7/23/2010 Other Health Professional Colombia
Primary
Secondary
Concomitant
Wheezing Other Serious 4/19/2009 67 Male 430 lb 7/27/2010 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Death 6/24/2010 32 Female 7/29/2010 Other Health Professional Colombia
Primary
Concomitant
Disease Progression Hospitalization 7/2/2010 47 Female 8/2/2010 Other Health Professional Colombia
Primary
Concomitant
Malignant Neoplasm Progression Death 7/15/2010 60 Female 8/6/2010 Other Health Professional Colombia
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 7/12/2010 47 Female 8/6/2010 Other Health Professional Colombia
Primary
Concomitant
Malignant Neoplasm Progression Death 6/23/2010 Female 8/6/2010 Other Health Professional Colombia
Primary
Concomitant
Malignant Neoplasm Progression Death 7/29/2010 50 Female 8/12/2010 Other Health Professional Colombia
Primary
Concomitant
Urinary Retention Other Serious 1/11/2007 56 Male 8/26/2010 Physician United States
Primary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 8/25/2010 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/17/2010 39 Female 83 lb 8/27/2010 Physician Brazil
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 8/29/2010 United States
Primary
Secondary
Concomitant
Tooth Impacted Other Serious 1/1/2005 42 Female 8/30/2010 United States
Primary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 9/1/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10/9/2001 65 Female 169 lb 9/6/2010 United States
Primary
Secondary
Concomitant
Toothache Other Serious 11/20/2006 61 Male 172 lb 9/9/2010 United States
Primary
Concomitant

Drug Data