Headache |
Other Serious |
|
81 |
Male |
132 lb |
8/4/2006 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vertigo |
Hospitalization |
7/29/2006 |
84 |
Female |
140 lb |
9/1/2006 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vitreous Floaters |
Other Serious |
|
76 |
Female |
175 lb |
10/3/2006 |
|
United States |
|
Visual Acuity Reduced |
Other Serious |
|
|
Female |
140 lb |
10/4/2006 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
|
|
Female |
140 lb |
10/4/2006 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vitreous Floaters |
|
|
76 |
Female |
175 lb |
10/12/2006 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
9/22/2006 |
|
Female |
140 lb |
10/25/2006 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
9/22/2006 |
|
Female |
140 lb |
10/25/2006 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Scar |
Other Serious |
|
|
Female |
282 lb |
12/8/2006 |
|
United States |
|
Retinal Haemorrhage |
Disability |
6/27/2006 |
62 |
Female |
168 lb |
12/13/2006 |
Physician |
India |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Vein Occlusion |
Other Serious |
|
90 |
Male |
|
12/27/2006 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Vein Occlusion |
Other Serious |
|
90 |
Male |
|
12/27/2006 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Intraocular Pressure Increased |
Other Serious |
12/1/2006 |
|
Female |
|
1/5/2007 |
Physician |
United States |
|
Vitreous Floaters |
|
|
76 |
Female |
175 lb |
1/27/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Oedema Peripheral |
Other Serious |
2/1/2007 |
74 |
Male |
175 lb |
2/14/2007 |
Consumer |
United States |
|
No Therapeutic Response |
Other Serious |
12/1/2006 |
86 |
Female |
|
2/15/2007 |
Physician |
United States |
|
Deep Vein Thrombosis |
Other Serious |
|
|
Male |
|
2/20/2007 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Oedema Peripheral |
Other Serious |
2/1/2007 |
74 |
Male |
175 lb |
2/21/2007 |
Consumer |
United States |
|
Oedema Peripheral |
Other Serious |
2/1/2007 |
74 |
Male |
175 lb |
2/21/2007 |
Consumer |
United States |
|
Deep Vein Thrombosis |
Other Serious |
|
|
Male |
|
2/20/2007 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Deep Vein Thrombosis |
Other Serious |
2/1/2007 |
74 |
Male |
175 lb |
2/23/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Oedema Peripheral |
Other Serious |
2/1/2007 |
74 |
Male |
175 lb |
2/23/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Haemorrhage |
Disability |
6/27/2006 |
62 |
Female |
168 lb |
3/5/2007 |
Physician |
India |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
3/5/2007 |
82 |
Female |
|
3/26/2007 |
Physician |
Germany |
|
Visual Acuity Reduced |
Other Serious |
3/5/2007 |
82 |
Female |
|
3/26/2007 |
Physician |
Germany |
|
Scotoma |
Other Serious |
|
85 |
Male |
|
4/2/2007 |
Consumer |
United States |
|
Visual Disturbance |
Other Serious |
|
85 |
Male |
|
4/2/2007 |
Consumer |
United States |
|
Haemorrhage |
Other Serious |
2/1/2007 |
|
Male |
|
4/11/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haemorrhage |
Other Serious |
2/1/2007 |
|
Male |
|
4/11/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Thrombosis |
Other Serious |
|
|
Male |
|
4/12/2007 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Transient Ischaemic Attack |
Other Serious |
|
78 |
Male |
|
4/4/2007 |
Consumer |
United States |
|
Retinal Haemorrhage |
Other Serious |
|
|
Female |
282 lb |
4/18/2007 |
Consumer |
United States |
|
Cataract |
Other Serious |
11/1/2006 |
|
Male |
|
4/19/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Oedema |
Other Serious |
3/27/2007 |
|
Male |
|
4/19/2007 |
Consumer |
Switzerland |
|
Retinal Oedema |
Other Serious |
3/27/2007 |
|
Male |
|
4/19/2007 |
Consumer |
Switzerland |
|
Thrombosis |
Other Serious |
|
|
Male |
|
4/30/2007 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Intraocular Pressure Increased |
Other Serious |
2/3/2007 |
|
Female |
|
5/1/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Haemorrhage |
Disability |
8/10/2006 |
|
Male |
|
5/3/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Haemorrhage |
Disability |
8/10/2006 |
|
Male |
|
5/3/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
4/12/2007 |
|
Male |
|
5/7/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
Other Serious |
4/12/2007 |
|
Male |
|
5/7/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Drug Ineffective |
|
|
|
Female |
|
2/28/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vitreous Floaters |
|
|
|
Female |
190 lb |
2/28/2007 |
Consumer |
United States |
|
Nausea |
|
10/1/2006 |
86 |
Female |
180 lb |
2/28/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Acuity Reduced |
|
|
|
Female |
|
2/28/2007 |
Consumer |
United States |
|
Visual Disturbance |
Other Serious |
4/19/2007 |
|
Male |
174 lb |
6/8/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Other Serious |
4/19/2007 |
|
Male |
174 lb |
6/8/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Uveitis |
Other Serious |
|
|
Female |
|
6/21/2007 |
Physician |
United States |
|
Visual Disturbance |
Other Serious |
10/1/2006 |
|
Female |
|
7/18/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Other Serious |
10/1/2006 |
|
Female |
|
7/18/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Coagulopathy |
Other Serious |
6/17/2007 |
|
Female |
220 lb |
7/17/2007 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Haemorrhage |
Disability |
8/10/2006 |
|
Male |
|
7/31/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Haemorrhage |
Disability |
8/10/2006 |
|
Male |
|
7/31/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Intraocular Pressure Increased |
Other Serious |
2/3/2007 |
|
Female |
|
8/10/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Pain |
Other Serious |
12/28/2006 |
|
Female |
|
8/20/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Nerve Injury |
Other Serious |
12/28/2006 |
|
Female |
|
8/20/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Drug Ineffective |
Other Serious |
12/2/2006 |
|
Male |
|
8/20/2007 |
Consumer |
United States |
|
Haematoma |
Hospitalization |
|
|
Female |
|
9/5/2007 |
Consumer |
Switzerland |
|
Haematoma |
Hospitalization |
|
|
Female |
|
9/5/2007 |
Consumer |
Switzerland |
|
Cerebrovascular Accident |
Hospitalization |
11/7/2006 |
|
Male |
220 lb |
8/25/2007 |
Consumer |
United States |
|
Cerebellar Infarction |
Hospitalization |
7/29/2006 |
|
Female |
140 lb |
9/12/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebellar Infarction |
Hospitalization |
7/29/2006 |
|
Female |
140 lb |
9/12/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haematoma |
Hospitalization |
6/12/2007 |
|
Female |
|
10/1/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haematoma |
Hospitalization |
6/12/2007 |
|
Female |
|
10/1/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
|
4/1/2007 |
85 |
Male |
184 lb |
7/5/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Discharge |
|
3/1/2007 |
85 |
Female |
|
7/5/2007 |
Consumer |
United States |
|
Drug Ineffective |
|
|
81 |
Male |
|
7/5/2007 |
Consumer |
United States |
|
Macular Scar |
|
|
|
Male |
|
7/5/2007 |
Consumer |
United States |
|
Eye Pain |
|
|
|
Female |
142 lb |
7/5/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Intraocular Pressure Increased |
Other Serious |
2/3/2007 |
80 |
Female |
|
7/5/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Uveitis |
Other Serious |
|
|
Female |
|
7/5/2007 |
Physician |
United States |
|
Cataract |
Other Serious |
11/1/2006 |
77 |
Male |
|
7/5/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Other Serious |
10/1/2006 |
|
Female |
|
10/8/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Other Serious |
10/1/2006 |
|
Female |
|
10/8/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Headache |
Other Serious |
7/19/2006 |
|
Male |
132 lb |
10/9/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Headache |
Other Serious |
7/19/2006 |
|
Male |
132 lb |
10/9/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Transient Ischaemic Attack |
Other Serious |
6/17/2007 |
|
Female |
220 lb |
10/3/2007 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Rhinorrhoea |
Other Serious |
12/28/2006 |
|
Female |
|
10/15/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Eye Pain |
Other Serious |
12/28/2006 |
|
Female |
|
10/15/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haematoma |
Hospitalization |
6/12/2007 |
|
Female |
|
10/16/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haematoma |
Hospitalization |
6/12/2007 |
|
Female |
|
10/16/2007 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Malaise |
Hospitalization |
5/18/2007 |
|
Male |
175 lb |
10/17/2007 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Malaise |
Hospitalization |
5/18/2007 |
|
Male |
175 lb |
10/17/2007 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Hospitalization |
10/23/2007 |
|
Male |
220 lb |
10/23/2007 |
Consumer |
United States |
|
Vitreous Floaters |
Other Serious |
|
|
Female |
|
10/23/2007 |
Consumer |
United States |
|
Cerebrovascular Accident |
Hospitalization |
|
|
Male |
220 lb |
11/1/2007 |
Consumer |
United States |
|
Cerebrovascular Accident |
Hospitalization |
|
|
Male |
220 lb |
11/8/2007 |
Consumer |
United States |
|
Cerebrovascular Accident |
Hospitalization |
|
|
Male |
220 lb |
11/8/2007 |
Consumer |
United States |
|
Pruritus |
Other Serious |
10/15/2007 |
|
Male |
|
11/12/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pruritus |
Other Serious |
10/15/2007 |
|
Male |
|
11/12/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Detachment |
Other Serious |
7/11/2007 |
|
Female |
131 lb |
11/17/2007 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Retinal Detachment |
Other Serious |
7/11/2007 |
|
Female |
131 lb |
11/17/2007 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Other Serious |
|
|
Female |
132 lb |
11/19/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Hospitalization |
7/31/2007 |
|
Male |
|
11/26/2007 |
Physician |
United States |
|
Cerebrovascular Accident |
Other Serious |
|
|
Female |
132 lb |
11/26/2007 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Hospitalization |
7/31/2007 |
|
Male |
|
11/27/2007 |
Physician |
United States |
|
Cerebellar Infarction |
Hospitalization |
7/29/2006 |
|
Female |
140 lb |
12/11/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Detachment Of Retinal Pigment Epithelium |
Other Serious |
|
75 |
Male |
|
2/16/2008 |
Physician |
United States |
|
Eye Haemorrhage |
Other Serious |
|
75 |
Male |
|
2/16/2008 |
Physician |
United States |
|
Endophthalmitis |
Other Serious |
|
|
|
|
4/15/2008 |
Consumer |
Switzerland |
|
Deafness |
Other Serious |
|
51 |
Male |
|
4/17/2008 |
Consumer |
United States |
|
Deafness |
Other Serious |
|
51 |
Male |
|
4/17/2008 |
Consumer |
United States |
|
Cerebrovascular Accident |
Other Serious |
2/26/2007 |
85 |
Female |
132 lb |
2/28/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Endophthalmitis |
Other Serious |
|
|
|
|
4/29/2008 |
Consumer |
Switzerland |
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/1/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/1/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/6/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/6/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/14/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Visual Disturbance |
Hospitalization |
|
|
Male |
265 lb |
5/14/2008 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cardiac Failure |
Death |
4/6/2008 |
85 |
Male |
|
5/20/2008 |
Physician |
Switzerland |
|
Cardiac Failure |
Death |
4/6/2008 |
85 |
Male |
|
5/20/2008 |
Physician |
Switzerland |
|
Cerebrovascular Accident |
Hospitalization |
11/8/2006 |
|
Male |
220 lb |
5/21/2008 |
Consumer |
United States |
|
Cerebrovascular Accident |
Hospitalization |
11/8/2006 |
|
Male |
220 lb |
5/21/2008 |
Consumer |
United States |
|
Deafness |
Other Serious |
|
|
Male |
|
6/3/2008 |
Consumer |
United States |
|
Deafness |
Other Serious |
|
|
Male |
|
6/3/2008 |
Consumer |
United States |
|
Visual Disturbance |
Other Serious |
1/1/2008 |
87 |
Male |
|
6/27/2008 |
Physician |
United States |
|
Myocardial Infarction |
Life Threatening |
|
|
Male |
|
7/18/2008 |
Other Health Professional |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Myocardial Infarction |
Life Threatening |
|
|
Male |
|
7/18/2008 |
Other Health Professional |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Deafness |
Other Serious |
|
|
Male |
|
7/29/2008 |
Consumer |
United States |
|
Deafness |
Other Serious |
|
|
Male |
|
7/29/2008 |
Consumer |
United States |
|
Drug Ineffective |
Other Serious |
|
51 |
|
|
8/7/2008 |
Consumer |
Switzerland |
|
Macular Oedema |
Other Serious |
|
80 |
Female |
|
9/3/2008 |
Other Health Professional |
Switzerland |
|
Vitreous Haemorrhage |
Other Serious |
|
|
|
|
10/1/2008 |
Physician |
Austria |
Primary |
|
Secondary |
|
Concomitant |
|
|
Oedema Peripheral |
Other Serious |
2/1/2007 |
|
Male |
175 lb |
10/2/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
10/3/2008 |
Physician |
Switzerland |
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
10/3/2008 |
Physician |
Switzerland |
|
Cerebrovascular Accident |
Other Serious |
11/13/2006 |
|
Female |
|
10/9/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Other Serious |
11/13/2006 |
|
Female |
|
10/9/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Other Serious |
11/13/2006 |
|
Female |
|
10/10/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Other Serious |
11/13/2006 |
|
Female |
|
10/10/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Swelling |
Other Serious |
8/12/2008 |
68 |
Female |
|
10/23/2008 |
Physician |
United States |
|
Myodesopsia |
Other Serious |
|
|
Female |
|
11/6/2008 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Stress |
Other Serious |
|
|
Female |
|
11/6/2008 |
Consumer |
Switzerland |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
11/11/2008 |
Physician |
Switzerland |
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
11/11/2008 |
Physician |
Switzerland |
|
Osteoarthritis |
Other Serious |
|
74 |
Female |
|
11/11/2008 |
Consumer |
United States |
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
11/25/2008 |
Physician |
Switzerland |
|
Cerebrovascular Accident |
Hospitalization |
9/1/2008 |
|
Female |
|
11/25/2008 |
Physician |
Switzerland |
|
Visual Acuity Reduced |
Other Serious |
|
|
Male |
|
2/12/2009 |
Consumer |
Switzerland |
|
Visual Acuity Reduced |
Other Serious |
|
|
Male |
|
2/12/2009 |
Consumer |
Switzerland |
|
No Therapeutic Response |
Other Serious |
|
|
Male |
|
2/10/2009 |
Consumer |
Canada |
|
Optic Atrophy |
Other Serious |
|
81 |
Female |
|
2/18/2009 |
Physician |
United States |
|
Scotoma |
Other Serious |
|
|
Male |
|
2/16/2009 |
Consumer |
Canada |
|
Myocardial Infarction |
Life Threatening |
12/9/2008 |
85 |
Male |
|
2/20/2009 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Myocardial Infarction |
Life Threatening |
12/9/2008 |
85 |
Male |
|
2/20/2009 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Glaucoma |
Disability |
2/3/2009 |
|
Female |
115 lb |
2/26/2009 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Glaucoma |
Disability |
2/3/2009 |
|
Female |
115 lb |
2/26/2009 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Osteoarthritis |
Other Serious |
|
74 |
Female |
|
3/2/2009 |
Consumer |
United States |
|
Intraocular Pressure Increased |
Other Serious |
|
|
|
|
4/23/2009 |
|
United States |
|