Avastin combined with Leucovorin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Hospitalization 1/17/2006 73 Male 2/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haematocrit Decreased Hospitalization 8/1/2004 70 Male 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 12/27/2005 Male 255 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 1/1/2004 56 Female 128 lb 3/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 2/28/2006 Male 4/3/2006 Physician Canada
Primary
Secondary
Ventricular Fibrillation Life Threatening 2/14/2006 Male 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2006 55 Male 4/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Death 3/1/2006 Female 4/14/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Oesophagitis Death 3/1/2006 Female 4/24/2006 Consumer Australia
Primary
Secondary
Concomitant
Troponin I Hospitalization 2/21/2006 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Angina Pectoris Hospitalization 2/8/2006 Male 4/26/2006 Other Health Professional United States
Primary
Secondary
Renal Failure Hospitalization 4/7/2006 Female 5/3/2006 Other Health Professional Mexico
Primary
Secondary
Syncope Hospitalization 2/27/2006 Female 5/4/2006 Other Health Professional United States
Primary
Secondary
Troponin I Hospitalization 2/21/2006 Male 5/5/2006 Other Health Professional United States
Primary
Secondary
Thrombosis Hospitalization 4/3/2006 Male 176 lb 5/5/2006 Other Health Professional United States
Primary
Secondary
Oedema Peripheral Hospitalization 8/26/2005 Male 386 lb 5/9/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/12/2006 56 Male 161 lb 5/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 Female 169 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
Hepatitis Toxic Hospitalization 3/22/2006 Female 5/11/2006 Other Health Professional Bulgaria
Primary
Secondary
Ventricular Extrasystoles Hospitalization 2/28/2006 Male 5/11/2006 Physician Canada
Primary
Secondary
Thrombosis Other Serious 2/15/2006 Male 5/16/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 5/14/2006 Male 201 lb 5/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 Female 169 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/12/2006 56 Male 161 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 9/26/2005 60 Male 145 lb 5/29/2006 Other Health Professional United States
Primary
Concomitant
Nausea Life Threatening 5/14/2006 Male 201 lb 5/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/22/2005 61 Female 134 lb 5/30/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/9/2006 Female 5/29/2006 Physician United States
Primary
Secondary
Pleural Effusion Hospitalization 4/19/2006 Male 271 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 4/10/2006 Male 6/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Life Threatening 4/3/2006 6/8/2006 Other Health Professional United States
Primary
Secondary
Cerebrovascular Accident Hospitalization 5/25/2006 Male 166 lb 6/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 5/14/2006 Male 201 lb 6/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 6/28/2005 Female 6/19/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Rash Erythematous Disability 3/7/2006 34 Male 6/14/2006 Pharmacist United States
Primary
Concomitant
Coma Other Serious 75 Male 6/27/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/9/2006 60 Female 101 lb 8/30/2006 United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/9/2006 56 Male 176 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 6/9/2006 56 Male 176 lb 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 7/19/2006 67 Female 110 lb 9/11/2006 Other Health Professional United States
Primary
Secondary
Syncope Hospitalization 8/2/2006 Male 9/18/2006 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Death 6/1/2006 73 Female 9/18/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/30/2006 55 Female 233 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Dermatitis Acneiform 63 Female 254 lb 11/30/2006 Consumer United States
Primary
Concomitant
Fistula Other Serious 2/6/2007 Male 125 lb 9/14/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 9/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Disability 6/5/2006 Female 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 9/19/2007 51 Male 9/26/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased 3/1/2007 37 Female 9/26/2007 Consumer United States
Primary
Concomitant
Epilepsy Hospitalization 4/7/2007 51 Male 9/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Other Serious 63 Male 10/5/2007 Pharmacist United States
Primary
Concomitant
Acute Abdomen Hospitalization 45 Male 10/8/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/17/2007 53 Male 10/9/2007 Physician United States
Primary
Secondary
Death Death 10/12/2007 Consumer United Kingdom
Primary
Secondary
Pyrexia Hospitalization 9/3/2007 64 Male 161 lb 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/8/2006 Male 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Feeling Abnormal Hospitalization 8/15/2007 Male 198 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Hospitalization 8/15/2007 Male 198 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 8/7/2007 53 Male 10/19/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 8/26/2005 Male 386 lb 10/23/2007 Other Health Professional United States
Primary
Secondary
Septic Shock Death 9/28/2007 Male 10/24/2007 Consumer United Kingdom
Primary
Concomitant
Testicular Pain Disability 8/28/2007 Male 158 lb 10/25/2007 Consumer United Kingdom
Primary
Concomitant
Hepatic Failure Hospitalization 8/26/2005 Male 386 lb 10/29/2007 Other Health Professional United States
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Hospitalization 10/23/2007 63 Female 10/31/2007 Other Health Professional United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/1/2007 Male 200 lb 11/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 10/1/2007 63 Female 11/6/2007 Other Health Professional United States
Primary
Concomitant
Intestinal Obstruction Death 10/1/2007 Male 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Death Death 9/19/2007 51 Male 11/9/2007 Physician United States
Primary
Secondary
Cardiac Arrest 10/8/2007 58 Female 140 lb 12/12/2007 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Other Serious Male 158 lb 12/28/2007 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/1/2007 Male 200 lb 1/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Death 4/11/2007 76 Female 1/8/2008 Physician United States
Primary
Concomitant
Death Hospitalization 10/8/2007 58 Female 1/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/3/2008 74 Female 115 lb 1/11/2008 Other Health Professional United States
Primary
Secondary
Sepsis Other Serious 1/3/2008 74 Female 115 lb 1/22/2008 Other Health Professional United States
Primary
Secondary
Pigmentation Disorder 10/1/2007 69 Female 3/28/2008 Physician United States
Primary
Secondary
Concomitant
Vena Cava Thrombosis Hospitalization 10/13/2009 Female 125 lb 10/27/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Eosinophilia Other Serious 74 Male 11/17/2010 Physician United States
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Other Serious 60 Male 11/29/2010 Physician Japan
Primary
Secondary
Thrombocytopenia Hospitalization 5/23/2010 71 Male 12/10/2010 Physician France
Primary
Secondary
Concomitant
Chest Pain Hospitalization 4/11/2009 69 Female 12/14/2010 Consumer United States
Primary
Secondary
Blood Pressure Increased Other Serious 54 Male 1/18/2011 Other Health Professional Canada
Primary
Concomitant
Fibrin D Dimer Increased Hospitalization 8/23/2010 80 Female 159 lb 1/20/2011 Physician Poland
Primary
Concomitant
Anaemia Other Serious 10/9/2001 65 Female 169 lb 1/27/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypoxia Life Threatening 1/19/2011 80 Female 141 lb 1/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fibrin D Dimer Increased Hospitalization 8/23/2010 80 Female 159 lb 2/28/2011 Other Health Professional Poland
Primary
Concomitant
Death Hospitalization 21 Female 4/1/2011 Consumer United States
Primary
Secondary
Convulsion Hospitalization 3/18/2011 21 Female 4/6/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 2/21/2011 79 Female 131 lb 4/7/2011 Physician Ecuador
Primary
Concomitant
Neoplasm Malignant Death 51 Male 187 lb 4/13/2011 Other Health Professional United States
Primary
Secondary
Hypersensitivity Hospitalization 11/8/2010 63 Male 4/13/2011 Other Health Professional United States
Primary
Concomitant
Disease Progression Death Male 10/16/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious Male 148 lb 9/14/2012 Other Health Professional Us
Primary
Concomitant
Hypotension Hospitalization 6/19/2012 81 Male 130 lb 9/20/2012 Physician De
Primary
Secondary
Concomitant
Mental Disorder Due To A General Medical Condition Hospitalization 8/1/2012 58 Male 141 lb 8/28/2012 Physician De
Primary
Secondary
Death Death Male 8/28/2012 Physician Br
Primary
Concomitant
Death Death Male 8/29/2012 Physician Br
Primary
Concomitant
Death Death Female 8/29/2012 Physician Br
Primary
Concomitant
Death Death Female 8/29/2012 Physician Br
Primary
Concomitant
Death Death Male 8/30/2012 Physician Br
Primary
Concomitant
Death Death Male 8/30/2012 Physician Br
Primary
Concomitant
Death Death Female 8/30/2012 Physician Br
Primary
Concomitant
Death Death Female 8/31/2012 Physician Br
Primary
Concomitant
Death Death Male 8/31/2012 Physician Br
Primary
Concomitant
Death Death Male 8/31/2012 Physician Br
Primary
Concomitant
Death Death Female 8/31/2012 Physician Br
Primary
Concomitant
Death Death Female 8/31/2012 Physician Br
Primary
Concomitant
Death Death Male 8/31/2012 Physician Br
Primary
Concomitant
Ischaemic Stroke Other Serious 74 Male 10/26/2012 Physician Fr
Primary
Secondary
Concomitant
Death Death Female 9/4/2012 Physician Br
Primary
Concomitant
Death Death Male 9/4/2012 Physician Br
Primary
Concomitant
Neuropathy Peripheral Other Serious 65 Female 9/10/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 9/10/2012 Physician Us
Primary
Concomitant
Hypotension Hospitalization 8/30/2012 62 Female 102 lb Registered Nurse Us
Primary
Secondary
Death Death Female 9/17/2012 Physician Us
Primary
Concomitant
Vomiting Death Male 9/26/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious 8/9/2012 44 Female 99 lb 9/20/2012 Physician Ru
Primary
Secondary
Concomitant
Renal Failure Hospitalization Male 11/15/2012 Physician Us
Primary
Concomitant
Disease Progression Death Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Spontaneous Haematoma Death 7/4/2012 43 Female 123 lb 9/24/2012 Physician Kr
Primary
Secondary
Concomitant
Drug Intolerance Other Serious 1/22/2010 49 Female 12/24/2012 Pharmacist Us
Primary
Secondary
Concomitant
Metastases To Lung Other Serious 1/2003 Female 9/25/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious Female 12/4/2012 Physician Us
Primary
Secondary
Concomitant
Thrombocytopenia Death Male 9/26/2012 Physician Us
Primary
Secondary
Concomitant
Rash Other Serious Female 9/26/2012 Physician Us
Primary
Secondary
Death Death Female 9/26/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 4/4/2005 54 Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death Male 9/27/2012 Physician Us
Primary
Secondary
Pulmonary Mass Death 5/2004 Male 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 9/27/2012 Physician Us
Primary
Concomitant
Venous Thrombosis Hospitalization Male 10/1/2012 Physician Fr
Primary
Secondary
Urosepsis Hospitalization 8/4/2011 81 Male 10/1/2012 Physician Tw
Primary
Secondary
Death Death Male 183 lb 10/22/2012 Other Health Professional Us
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Death 8/9/2012 81 Male 10/5/2012 Physician Fr
Primary
Secondary
Concomitant
Stomatitis Other Serious Male 10/8/2012 Physician Us
Primary
Secondary
Concomitant
Disease Progression Other Serious 6/4/2012 60 Female 183 lb 10/10/2012 Physician Ru
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/13/2012 69 Male 154 lb 10/10/2012 Physician Ru
Primary
Concomitant
Nephrotic Syndrome Other Serious 1/2012 63 Male 10/11/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/4/2012 217 lb 10/9/2012 Other Health Professional Us
Primary
Secondary
Pulmonary Embolism Hospitalization 9/26/2012 67 Male 10/12/2012 Pharmacist Us
Primary
Concomitant
Pyrexia Hospitalization 10/4/2012 Male 217 lb 10/8/2012 Other Health Professional Us
Primary
Secondary
Posterior Reversible Encephalopathy Syndrome Hospitalization 9/18/2012 50 Male 153 lb 11/21/2012 Pharmacist Ca
Primary
Concomitant
Pyrexia Other Serious 2/2/2012 61 Female 110 lb 11/7/2012 Physician Lt
Primary
Concomitant
Vomiting Other Serious 10/16/2012 69 Female 194 lb 11/6/2012 Pharmacist Us
Primary
Concomitant
Speech Disorder Other Serious 5/2012 Male 172 lb 11/27/2012 Physician De
Primary
Concomitant
Renal Failure Other Serious 12/8/2010 63 Male 170 lb 12/26/2012 Pharmacist Us
Primary
Secondary
Renal Failure Other Serious Male 12/3/2012 Pharmacist Us
Primary
Concomitant
Angioedema Other Serious Female 12/24/2012 Physician Us
Primary
Concomitant
Wound Dehiscence Death 1/2/2008 35 Female 9/20/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data