Avastin combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Grand Mal Convulsion Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Convulsion Other Serious Female 2/21/2006 Physician United States
Primary
Secondary
Pneumothorax Required Intervention 6/1/2005 53 Female 4/11/2006 Physician Sweden
Primary
Secondary
Pneumothorax Required Intervention 6/1/2005 53 Female 4/11/2006 Physician Sweden
Primary
Secondary
Epistaxis 54 Female 3/1/2006 United States
Primary
Secondary
Concomitant
Dermatitis Acneiform 1/9/2006 37 Female 145 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 9/12/2005 64 Female 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 10/20/2005 36 Female 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 1/22/2006 Female 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/22/2006 Female 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumothorax Required Intervention 6/1/2005 53 Female 6/19/2006 Physician Sweden
Primary
Secondary
Pneumothorax Required Intervention 6/1/2005 53 Female 6/19/2006 Physician Sweden
Primary
Secondary
Epistaxis 54 Female 5/31/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Disorder Other Serious 36 Female 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious Female 6/6/2006 Physician United States
Primary
Secondary
Jaundice Required Intervention 10/1/2005 Female 6/6/2006 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 9/12/2005 64 Female 6/6/2006 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 10/20/2005 36 Female 6/6/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 36 Female 9/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 36 Female 9/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Required Intervention 8/31/2006 76 Female 147 lb 11/2/2006 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Other Serious 45 Female 11/21/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious Female 11/27/2006 United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 36 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 36 Female 1/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 2/18/2007 52 Female 112 lb 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 36 Female 3/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 36 Female 3/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Toothache Other Serious 8/2/2006 55 Female 189 lb 3/14/2007 United States
Primary
Concomitant
Cardiotoxicity Other Serious Female 3/8/2007 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Death 2/8/2007 61 Female 106 lb 3/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiotoxicity Other Serious 2/19/2007 64 Female 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 45 Female 5/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization Female 5/24/2007 Physician United States
Primary
Secondary
Dermatitis Acneiform 1/9/2006 37 Female 145 lb 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 2/18/2007 52 Female 112 lb 2/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Diarrhoea 5/29/2007 66 Female 174 lb 7/6/2007 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 7/3/2007 38 Female 7/16/2007 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/3/2007 38 Female 7/17/2007 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/3/2007 38 Female 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/3/2007 38 Female 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/3/2007 38 Female 9/6/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization Female 9/24/2007 Physician United States
Primary
Secondary
Hepatic Cirrhosis Other Serious Female 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious Female 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 11/13/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 11/13/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/29/2007 50 Female 158 lb 11/19/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/29/2007 50 Female 348 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Other Serious Female 245 lb 1/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Other Serious Female 2/28/2008 Consumer United States
Primary
Secondary
Nasal Septum Perforation Other Serious 55 Female 243 lb 2/28/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Hospitalization 7/25/2008 Female 8/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 71 Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Pain In Jaw Other Serious Female 10/10/2008 United States
Primary
Concomitant
Pemphigoid Other Serious 8/25/2008 Female 10/10/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Pain 8/1/2008 62 Female 10/10/2008 Consumer United States
Primary
Concomitant
Gingival Disorder Other Serious Female 12/4/2008 Pharmacist United States
Primary
Secondary
Gastrointestinal Perforation Other Serious Female 2/25/2009 Physician United States
Primary
Secondary
Gastrointestinal Perforation Other Serious 2/12/2009 Female 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 5/20/2009 70 Female 150 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 5/20/2009 70 Female 150 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 61 Female 5/29/2009 Physician Greece
Primary
Secondary
Concomitant
Death Death 7/8/2009 Female 7/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 7/23/2009 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 61 Female 7/31/2009 Consumer Greece
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 9/3/2009 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Death 7/8/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Fissures Other Serious 11/1/2006 Female 10/30/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 11/6/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Fissures Other Serious 1/1/2008 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cellulitis Other Serious 54 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cough Other Serious 11/1/2008 47 Female 11/30/2009 Consumer Greece
Primary
Secondary
Concomitant
Myelitis Transverse Other Serious 39 Female 199 lb 12/31/2009 Physician United States
Primary
Secondary
Concomitant
Metastatic Gastric Cancer Death 1/1/2009 1/27/2010 Physician Netherlands
Primary
Secondary
Malignant Neoplasm Progression Other Serious 57 Female 2/19/2010 Consumer Canada
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 47 Female 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Myelitis Transverse Disability 6/1/2009 Female 193 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/11/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/18/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/25/2010 United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 57 Female 3/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Disease Progression Death 1/1/2008 Female 3/31/2010 Physician Netherlands
Primary
Secondary
Wound Dehiscence Other Serious 3/12/2002 Female 201 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Death 1/1/2008 51 Female 4/1/2010 Physician Netherlands
Primary
Secondary
Tumour Marker Increased Other Serious 66 Female 4/5/2010 Consumer United States
Primary
Secondary
Wound Dehiscence Other Serious 4/17/2001 44 Female 201 lb 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/16/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 4/20/2010 United States
Primary
Concomitant
Disease Progression Death 1/1/2008 51 Female 4/28/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 4/17/2001 44 Female 201 lb 5/4/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 2/22/2010 51 Female 5/6/2010 Other Health Professional Spain
Primary
Secondary
Wheezing Other Serious 2/1/1998 66 Female 126 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 2/20/2010 51 Female 5/19/2010 Physician France
Primary
Secondary
Ulcerative Keratitis Other Serious 2/20/2010 51 Female 5/20/2010 Physician France
Primary
Secondary
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/26/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 4/1/2010 Female 6/4/2010 Consumer Spain
Primary
Secondary
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/30/2010 United States
Primary
Secondary
Concomitant
Device Failure Other Serious 12/3/2009 67 Female 112 lb 7/22/2010 Other Health Professional United States
Primary
Secondary
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 8/9/2010 54 Female 130 lb 8/10/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Hepatic Lesion Other Serious Female 8/23/2010 Physician United States
Primary
Secondary
Pyrexia Hospitalization 8/13/2010 43 Female 167 lb 8/23/2010 Other Health Professional United States
Primary
Concomitant
Effusion Hospitalization 4/1/2010 63 Female 123 lb 8/27/2010 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Hepatic Lesion Life Threatening 1/1/2010 48 Female 120 lb 9/16/2010 Physician United States
Primary
Secondary
Pyrexia Hospitalization 8/31/2010 43 Female 165 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Lesion Life Threatening 1/1/2010 48 Female 178 lb 9/27/2010 Physician United States
Primary
Secondary
Septic Shock Life Threatening Female 10/6/2010 Physician France
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 8/1/2010 46 Female 124 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 11/1/2010 Consumer United States
Primary
Secondary
Disease Progression Other Serious 11/16/2010 Consumer Finland
Primary
Secondary
Visual Impairment Other Serious Female 154 lb 12/13/2010 Physician Germany
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Female 12/15/2010 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 11/9/2010 60 Female 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Cystitis Other Serious 50 Female 194 lb 2/24/2011 Consumer United States
Primary
Secondary
Metastases To Meninges Other Serious 1/1/2004 3/25/2011 Physician United States
Primary
Concomitant
Jaw Disorder Other Serious 8/1/2010 72 Female 4/6/2011 Physician Germany
Primary
Concomitant
Palmar Erythema Hospitalization 4/18/2011 52 Male 141 lb 5/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Death 6/26/2010 46 Female 130 lb 5/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Disease Progression Other Serious 61 Female 6/10/2011 Physician Australia
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 1/1/2010 Female 6/13/2011 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 7/8/2011 39 Female 7/20/2011 Consumer United Kingdom
Primary
Secondary
Hydrocephalus Other Serious Female 8/1/2011 Pharmacist Germany
Primary
Secondary
Cachexia Other Serious 3/1/2011 51 Female 8/5/2011 Physician United States
Primary
Concomitant
Dizziness Other Serious 3/1/2011 51 Female 8/19/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 8/19/2011 65 Female 216 lb 8/22/2011 Other Health Professional United States
Primary
Concomitant

Drug Data