Avastin combined with Folinic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Hospitalization 2/8/2006 Male 2/21/2006 Physician United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 1/5/2006 Male 5/24/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Death 10/27/2005 Male 7/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/17/2006 57 Male 7/21/2006 Physician Tunisia
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/5/2006 66 Female 8/8/2006 Physician United States
Primary
Secondary
Septic Shock Life Threatening 8/5/2006 Male 8/31/2006 Other Health Professional Brazil
Primary
Secondary
Febrile Neutropenia Life Threatening 7/5/2006 Female 9/4/2006 Physician United States
Primary
Secondary
Sepsis Life Threatening 8/5/2006 Male 10/3/2006 Other Health Professional Brazil
Primary
Secondary
Dyspnoea Death 5/21/2006 Female 11/2/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 10/15/2006 Female 11/2/2006 Physician United States
Primary
Secondary
Concomitant
Ectropion Other Serious 10/10/2006 Female 11/10/2006 Physician United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/20/2006 Male 12/20/2006 Physician United States
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 11/26/2006 Female 12/20/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/16/2006 Female 12/27/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 1/11/2007 Physician United States
Primary
Concomitant
Peritoneal Infection Hospitalization 11/26/2006 Female 1/22/2007 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 2/2/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 2/26/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 3/14/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 12/16/2006 Female 3/16/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/13/2007 Male 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/13/2007 68 Male 137 lb 4/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Life Threatening 62 Female 163 lb 4/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/14/2006 Male 4/12/2007 Physician United States
Primary
Concomitant
Renal Disorder Other Serious Female 4/17/2007 Other Health Professional United States
Primary
Concomitant
Hiccups Other Serious 4/19/2007 Consumer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 2/23/2007 69 Male 4/19/2007 Consumer United Kingdom
Primary
Concomitant
Death Death Female 4/24/2007 Physician United Kingdom
Primary
Concomitant
Colonic Stenosis Hospitalization Male 5/9/2007 Physician United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 3/14/2006 Male 5/14/2007 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 3/1/2007 60 Male 5/17/2007 Physician United Kingdom
Primary
Concomitant
Tremor Hospitalization Female 5/17/2007 Other Health Professional United States
Primary
Secondary
Photodermatosis Other Serious 1/1/2007 Male 5/18/2007 Physician Germany
Primary
Secondary
Colonic Stenosis Hospitalization Male 5/22/2007 Physician United States
Primary
Concomitant
Convulsion Other Serious 4/6/2007 Male 196 lb 5/25/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 4/6/2006 Male 6/6/2007 Physician United Kingdom
Primary
Concomitant
Renal Disorder Other Serious Female 6/8/2007 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious Male 6/12/2007 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious Male 6/19/2007 Physician United Kingdom
Primary
Concomitant
Respiratory Paralysis Hospitalization Male 6/20/2007 Physician United Kingdom
Primary
Concomitant
Death Death Female 151 lb 6/26/2007 Consumer United States
Primary
Concomitant
Jaundice Hospitalization 4/2/2007 59 Female 134 lb 7/3/2007 Consumer United States
Primary
Concomitant
Spinal Cord Ischaemia Hospitalization Male 7/5/2007 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance 1/1/2007 Male 7/30/2007 Physician Germany
Primary
Secondary
Colonic Stenosis Hospitalization Male 7/31/2007 Physician United States
Primary
Concomitant
Death Death 1/1/2007 Male 7/31/2007 Consumer United Kingdom
Primary
Concomitant
Death Death Female 151 lb 8/2/2007 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 7/19/2007 Female 8/2/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 7/19/2007 61 Male 269 lb 8/17/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/28/2007 Female 8/17/2007 United Kingdom
Primary
Secondary
Pyrexia Other Serious Male 8/28/2007 Pharmacist Germany
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 8/29/2007 Physician United Kingdom
Primary
Concomitant
Face Oedema Life Threatening 7/3/2007 38 Male 8/29/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Oedema Other Serious 8/2/2007 44 Female 8/29/2007 Physician Finland
Primary
Concomitant
Venous Stasis Other Serious 80 Female 9/4/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 9/4/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 4/3/2007 Male 165 lb 9/21/2007 Physician United Kingdom
Primary
Concomitant
Urinary Fistula Hospitalization 4/1/2006 Male 172 lb 9/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Obstruction Other Serious Male 9/24/2007 Physician United States
Primary
Concomitant
Face Oedema Life Threatening 7/3/2007 38 Male 9/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 52 Male 10/2/2007 Physician United States
Primary
Concomitant
Tachycardia Death Male 218 lb 10/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Small Intestinal Obstruction Other Serious 7/19/2007 Female 10/5/2007 Physician United States
Primary
Secondary
Anaemia Hospitalization 8/13/2007 Female 106 lb 10/9/2007 Consumer France
Primary
Secondary
Concomitant
Proteinuria Hospitalization 9/7/2007 72 Male 10/11/2007 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Hospitalization 51 Male 10/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tachycardia Death Male 218 lb 10/18/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/19/2006 Male 10/26/2007 Consumer United Kingdom
Primary
Secondary
Small Intestinal Obstruction Hospitalization Female 10/26/2007 Consumer United States
Primary
Concomitant
Skin Ulcer Life Threatening 7/26/2007 Female 11/2/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/19/2006 Male 11/2/2007 Consumer United Kingdom
Primary
Secondary
Skin Fissures Other Serious 8/13/2007 Male 11/13/2007 Consumer United Kingdom
Primary
Concomitant
Gingivitis Ulcerative Other Serious Female 11/14/2007 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 71 Male 11/14/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 11/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Male 11/19/2007 Physician Germany
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/1/2007 43 Female 11/20/2007 Physician Brazil
Primary
Concomitant
Epilepsy Other Serious 37 Male 11/20/2007 Physician United Kingdom
Primary
Concomitant
Skin Toxicity Other Serious 57 Female 11/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious Male 11/21/2007 Physician United Kingdom
Primary
Secondary
Myocardial Infarction Hospitalization 9/17/2007 52 Male 11/21/2007 Physician United States
Primary
Secondary
Pneumonia Life Threatening 8/7/2007 Male 201 lb 11/30/2007 Physician Germany
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious Male 11/30/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/17/2004 73 Female 143 lb 11/20/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 8/7/2007 Male 201 lb 12/5/2007 Physician Germany
Primary
Secondary
Concomitant
Hepatic Necrosis Death 65 Male 12/5/2007 Physician United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Hospitalization Female 12/12/2007 Consumer United States
Primary
Concomitant
Lymphangiosis Carcinomatosa Other Serious 10/1/2007 Male 12/17/2007 Physician United Kingdom
Primary
Secondary
Anaphylactic Reaction Other Serious Female 12/20/2007 Pharmacist United Kingdom
Primary
Concomitant
Small Intestinal Obstruction Life Threatening 12/16/2006 Female 12/21/2007 Physician United States
Primary
Concomitant
Skin Necrosis Other Serious Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Convulsion Life Threatening 9/21/2007 Male 172 lb 1/8/2008 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 9/1/2007 Male 200 lb 1/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 12/16/2006 Female 1/8/2008 Physician United States
Primary
Concomitant
Metastases To Liver Other Serious 12/1/2007 Male 1/9/2008 Physician United Kingdom
Primary
Secondary
Bone Disorder Other Serious 12/3/2007 Male 216 lb 1/15/2008 Other Health Professional Germany
Primary
Concomitant
Tumour Lysis Syndrome Death 62 Male 1/15/2008 Physician Germany
Primary
Concomitant
Dermatitis Exfoliative Other Serious 11/8/2007 Female 110 lb 1/18/2008 Pharmacist United Kingdom
Primary
Concomitant
Urinary Fistula Hospitalization 4/1/2006 Male 172 lb 1/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Life Threatening 1/1/2007 77 Male 185 lb 1/24/2008 Physician United Kingdom
Primary
Concomitant
Malnutrition Hospitalization 12/1/2007 82 Female 1/25/2008 Physician United Kingdom
Primary
Secondary
Epilepsy Other Serious 37 Male 1/26/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 1/3/2008 Female 1/28/2008 Physician United States
Primary
Secondary
Death Death 1/1/2007 77 Male 185 lb 2/1/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 5/1/2007 82 Female 2/1/2008 Physician Taiwan, Province Of China
Primary
Secondary
Jaundice Hospitalization 8/30/2007 Male 176 lb 2/4/2008 Physician United Kingdom
Primary
Concomitant
Sepsis Life Threatening 1/3/2008 Female 2/5/2008 Physician United States
Primary
Secondary
Muscular Weakness Other Serious 48 Female 2/6/2008 Consumer United States
Primary
Concomitant
Fibromuscular Dysplasia Other Serious 12/1/2007 72 Male 2/6/2008 Consumer United States
Primary
Concomitant
Metastases To Liver Hospitalization 12/1/2007 Male 134 lb 2/7/2008 Physician United Kingdom
Primary
Secondary
Septic Shock Other Serious 8/6/2007 Male 154 lb 2/14/2008 Pharmacist Germany
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/16/2007 56 Female 2/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 2/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 12/1/2007 Male 2/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/3/2008 Female 2/26/2008 Physician United States
Primary
Secondary
Scotoma Other Serious Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Necrosis Other Serious 68 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Hypokalaemia Hospitalization 9/1/2007 Female 3/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 3/18/2006 Male 186 lb 3/11/2008 Other Health Professional Canada
Primary
Concomitant
Haemorrhage Other Serious Male 3/11/2008 Consumer United Kingdom
Primary
Concomitant
Pruritus Other Serious 2/11/2008 63 Male 3/20/2008 Physician United Kingdom
Primary
Concomitant
Scotoma Other Serious 1/1/2008 61 Male 3/24/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Scar 50 Female 3/28/2008 Consumer United States
Primary
Concomitant
Anaphylactic Reaction Hospitalization 3/26/2008 Male 4/4/2008 Consumer United Kingdom
Primary
Concomitant
Transaminases Increased Hospitalization 8/30/2007 Male 176 lb 4/18/2008 Physician France
Primary
Secondary
Concomitant
Hypotension Hospitalization 3/26/2008 Male 150 lb 4/24/2008 Consumer United Kingdom
Primary
Concomitant
Dermatitis Allergic Disability 2/28/2008 Male 4/24/2008 Consumer United Kingdom
Primary
Concomitant
Prothrombin Time Shortened Hospitalization 9/1/2007 Female 4/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 9/1/2007 Female 5/7/2008 Other Health Professional France
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 8/30/2007 Male 176 lb 5/13/2008 Physician France
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/22/2008 Female 5/13/2008 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Perforation Death 9/2/2007 Male 216 lb 5/14/2008 Consumer Ireland
Primary
Concomitant
Peritonitis Life Threatening 11/26/2007 Female 139 lb 5/14/2008 Physician United Kingdom
Primary
Concomitant
Pneumonitis Other Serious Male 5/29/2008 Consumer United States
Primary
Secondary
Sigmoiditis Hospitalization Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Scotoma Other Serious 1/1/2008 61 Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Psoriasis Hospitalization 5/18/2008 61 Male 6/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Skin Haemorrhage Hospitalization 5/18/2008 61 Male 6/5/2008 Physician Israel
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 55 Male 6/9/2008 Physician United Kingdom
Primary
Concomitant
Retinal Haemorrhage Other Serious 75 Male 6/19/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 5/14/2008 Female 7/11/2008 Physician United Kingdom
Primary
Secondary
Small Intestinal Obstruction Hospitalization 1/1/2008 50 Male 7/11/2008 Physician United Kingdom
Primary
Concomitant
Prothrombin Level Decreased Other Serious Female 7/14/2008 Physician United Kingdom
Primary
Concomitant
Ureteric Rupture Life Threatening 5/18/2008 Male 7/18/2008 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 6/11/2008 Male 7/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 6/18/2008 Female 7/25/2008 Consumer Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening Male 185 lb 7/30/2008 Physician United Kingdom
Primary
Concomitant
Jaundice Hospitalization 7/15/2008 Male 8/1/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant

Drug Data