Avastin combined with Famotidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metastases To Central Nervous System Life Threatening 3/1/2006 57 Female 3/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Screaming Hospitalization 3/9/2006 55 Female 220 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Screaming Hospitalization 3/9/2006 55 Female 220 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Disease Progression Death 12/7/2004 Male 116 lb 7/24/2006 Physician United States
Primary
Concomitant
Back Pain 12/14/2006 69 Female 143 lb 2/28/2007 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 3/11/2007 Female 126 lb 4/18/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/11/2007 Female 126 lb 5/8/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/3/2007 40 Male 255 lb 7/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 12/10/2007 40 Male 284 lb 12/14/2007 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 4/10/2007 56 Male 1/18/2008 United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 3/31/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 4/3/2008 Consumer United Kingdom
Primary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 5/23/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/9/2008 Female 6/2/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 Male 157 lb 6/12/2008 Consumer United Kingdom
Primary
Concomitant
Neuropathy Peripheral Hospitalization 5/23/2008 62 Female 6/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 4/13/2008 Female 6/21/2008 Consumer United Kingdom
Primary
Concomitant
Hepatic Function Abnormal Other Serious 6/11/2008 51 Female 135 lb 7/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sneezing Other Serious 3/6/2008 Female 141 lb 8/19/2008 Consumer Japan
Primary
Concomitant
Hepatitis Other Serious 6/11/2008 Female 135 lb 12/19/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Liver Abscess Other Serious 1/16/2009 Male 75 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 4/3/2008 Male 2/12/2009 Consumer Japan
Primary
Concomitant
Liver Abscess Other Serious 1/16/2009 Male 75 lb 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Coma Other Serious 3/12/2009 76 Male 112 lb 4/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 9/27/2008 Female 7/17/2009 Physician United Kingdom
Primary
Concomitant
Renal Neoplasm Hospitalization 9/15/2009 42 Female 10/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Neoplasm Hospitalization 9/15/2009 42 Female 10/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/15/2009 Male 149 lb 10/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Disturbance Hospitalization 9/15/2009 42 Female 10/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Sensory Loss Hospitalization 9/15/2009 42 Female 10/29/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/27/2008 Female 11/2/2009 Physician Japan
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/20/2010 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 2/11/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 2/13/2010 Male 170 lb 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 2/13/2010 Male 170 lb 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/5/2010 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 3/1/2010 Female 128 lb 3/8/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/15/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 3/22/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/22/2009 Male 88 lb 3/24/2010 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 5/25/2007 41 Female 4/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/22/2009 62 Male 88 lb 4/6/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2007 41 Female 4/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 5/25/2007 41 Female 4/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 2/1/2010 74 Male 152 lb 5/7/2010 Physician Japan
Primary
Secondary
Concomitant
Interacting
Weight Decreased Hospitalization 9/22/2009 48 Male 170 lb 5/11/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 2/13/2010 48 Male 170 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/3/2009 67 Male 106 lb 5/21/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2009 48 Male 88 lb 5/27/2010 Physician Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 3/1/2010 62 Female 128 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 2/13/2010 48 Male 170 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Death 5/4/2010 64 Male 115 lb 6/7/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Gastrointestinal Perforation Life Threatening 2/24/2010 67 Female 80 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Duodenal Perforation Life Threatening 2/24/2010 67 Female 80 lb 6/22/2010 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 4/21/2010 66 Male 112 lb 7/1/2010 Physician Japan
Primary
Secondary
Duodenal Perforation Life Threatening 2/24/2010 67 Female 80 lb 7/6/2010 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Other Serious 4/21/2010 66 Male 112 lb 7/7/2010 Physician Japan
Primary
Secondary
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 7/13/2010 United States
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 7/20/2010 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 74 Female 8/13/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 8/17/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/24/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/31/2010 United States
Primary
Concomitant
Sepsis Other Serious 6/26/2010 81 Female 9/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Peptic Ulcer Other Serious 7/31/2010 60 Female 88 lb 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Vena Cava Filter Insertion Hospitalization 2/13/2010 48 Male 170 lb 10/14/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 10/19/2010 Other Health Professional United States
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 11/11/2010 United States
Primary
Concomitant
Walking Aid User Other Serious 7/1/2004 74 Female 11/17/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Weight Increased Other Serious 6/1/2006 47 Female 12/7/2010 Other Health Professional United States
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 12/20/2010 United States
Primary
Concomitant
Pneumonia Hospitalization 12/3/2010 66 Female 101 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 4/6/2010 79 Male 148 lb 1/24/2011 Other Health Professional Japan
Primary
Concomitant
Metabolic Syndrome Hospitalization 6/1/2006 47 Female 1/26/2011 Physician United States
Primary
Concomitant
Hypoaesthesia Hospitalization 10/18/2010 68 Female 106 lb 2/18/2011 Other Health Professional Japan
Primary
Concomitant
Abdominal Distension Death 5/16/2010 58 Male 170 lb 2/21/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Distension Death 5/16/2010 58 Male 170 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/1/2009 64 Female 3/2/2011 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/1/2009 64 Female 3/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Life Threatening 2/17/2011 61 Female 121 lb 3/15/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/1/2009 64 Female 3/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/1/2009 64 Female 3/18/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/1/2009 64 Female 3/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Acute Sinusitis Hospitalization 6/1/2006 47 Female 4/6/2011 Lawyer United States
Primary
Concomitant
Laryngeal Oedema Life Threatening 2/17/2011 61 Female 121 lb 4/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 60 Female 121 lb 5/5/2011 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 6/11/2010 65 Female 101 lb 5/20/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 12/16/2010 68 112 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 5/1/2011 65 Male 179 lb 6/2/2011 Physician Japan
Primary
Concomitant
Decreased Appetite Other Serious 9/17/2007 61 Male 134 lb 6/13/2011 Physician Japan
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 6/1/2006 47 Female 6/23/2011 Other Health Professional United States
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 6/18/2010 66 Male 108 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/1/2009 64 Female 7/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoxic-ischaemic Encephalopathy Other Serious 6/1/2011 64 Male 134 lb 7/15/2011 Other Health Professional Japan
Primary
Concomitant
Hiccups Life Threatening 1/21/2011 73 Male 123 lb 7/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 10/3/2003 46 Female 128 lb 7/20/2011 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 11/27/2010 66 Male 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Other Serious 3/29/2011 60 Male 110 lb 7/29/2011 Other Health Professional Japan
Primary
Concomitant
Aortic Dissection Life Threatening 12/16/2010 73 Male 123 lb 8/4/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Other Serious 12/18/2009 56 Female 117 lb 8/17/2011 Physician Japan
Primary
Secondary
Concomitant
Hypertension Death 1/1/2011 63 Male 115 lb 8/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertension Death 1/1/2011 63 Male 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Arthralgia Life Threatening 12/16/2010 73 Male 123 lb 8/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 6/25/2011 75 Male 169 lb 8/29/2011 Physician United States
Primary
Secondary
Concomitant
Convulsion Death 6/10/2011 68 Male 210 lb 8/31/2011 Consumer Canada
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 6/25/2011 75 Male 169 lb 9/1/2011 Other Health Professional United States
Primary
Concomitant
Palpitations Death 12/1/2010 69 Male 9/14/2011 Physician Japan
Primary
Secondary
Concomitant
Palpitations Hospitalization 12/1/2010 69 Male 9/22/2011 Consumer Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 11/27/2010 67 Male 10/4/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 12/1/2010 69 Male 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Hyperammonaemia Other Serious 8/26/2011 72 Female 10/21/2011 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 6/1/2009 64 Female 119 lb 11/1/2011 Japan
Primary
Secondary
Concomitant
Peptic Ulcer Other Serious 7/31/2010 60 Female 88 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 10/31/2011 89 Female 108 lb 11/16/2011 Physician Japan
Primary
Secondary
Concomitant
Mesenteric Vein Thrombosis Hospitalization 9/26/2008 46 Male 108 lb 11/23/2011 Physician Japan
Primary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 11/24/2011 United States
Primary
Secondary
Concomitant
Palpitations Death 12/1/2010 69 Male 11/30/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 11/11/2011 72 Male 265 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Insomnia Other Serious 6/15/2010 67 Male 128 lb 12/8/2011 Physician Japan
Primary
Concomitant
Cardiac Arrest Death 11/11/2011 72 Male 225 lb 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/28/2011 66 Male 381 lb 12/15/2011 Japan
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 11/2/2011 67 Male 157 lb 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death 10/21/2010 61 Male 104 lb 1/2/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Radiculopathy Other Serious 7/1/2004 74 Female 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 6/18/2010 66 Male 108 lb 1/6/2012 Japan
Primary
Secondary
Concomitant
Death Hospitalization 1/3/2011 79 Female 140 lb 1/12/2012 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/21/2011 76 Female 84 lb 1/17/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Hospitalization 1/3/2011 79 Female 140 lb 1/17/2012 United States
Primary
Secondary
Concomitant
Cholangitis Hospitalization 1/8/2012 55 Female 229 lb 1/17/2012 United States
Primary
Secondary
Concomitant
Device Related Sepsis Other Serious 7/8/2011 72 Female 123 lb 1/25/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 10/29/2010 47 Female 93 lb 2/2/2012 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 12/16/2011 68 Female 123 lb 2/6/2012 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 12/21/2011 84 Male 95 lb 2/6/2012 Physician Japan
Primary
Secondary
Concomitant
Pruritus Generalised Hospitalization 9/17/2011 61 Male 2/9/2012 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious 10/1/2011 68 Female 123 lb 2/23/2012 Physician Japan
Primary
Secondary
Concomitant
Hypertension Death 1/1/2011 63 Male 115 lb 2/27/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 7/26/2011 63 Male 115 lb 3/5/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileal Perforation Other Serious 12/13/2010 45 Male 172 lb 3/13/2012 Japan
Primary
Secondary
Concomitant

Drug Data