Avastin combined with Elplat

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 10/11/2007 Female 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Death Death 10/11/2007 Female 12/10/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/24/2007 Male 12/18/2007 Physician Japan
Primary
Secondary
Concomitant
Rectal Perforation Life Threatening 12/6/2007 54 Female 1/24/2008 Other Health Professional Japan
Primary
Secondary
Acute Respiratory Distress Syndrome Hospitalization 1/28/2008 Male 2/21/2008 Physician Japan
Primary
Secondary
Disseminated Intravascular Coagulation Other Serious 1/22/2008 Male 2/23/2008 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/22/2008 Male 3/6/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 2/22/2008 70 Male 3/7/2008 Physician Japan
Primary
Secondary
Neutrophil Count Decreased Other Serious 7/30/2007 Male 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 1/25/2008 Male 3/21/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/28/2008 Male 3/28/2008 Physician Japan
Primary
Secondary
Pulmonary Artery Thrombosis Other Serious 2/20/2008 73 Male 133 lb 4/14/2008 Physician Japan
Primary
Secondary
Thrombotic Cerebral Infarction Life Threatening 3/16/2008 54 Male 4/14/2008 Physician Japan
Primary
Secondary
Gastrointestinal Perforation Other Serious 2/13/2008 Female 4/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 1/25/2008 Male 4/18/2008 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 12/6/2007 Female 4/22/2008 Physician Japan
Primary
Secondary
Gastrointestinal Perforation Other Serious 2/13/2008 48 Female 104 lb 4/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/30/2007 Male 4/23/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 3/14/2008 Male 4/23/2008 Physician Japan
Primary
Secondary
Intestinal Fistula Other Serious 12/6/2007 Male 4/24/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 11/27/2007 70 Male 4/24/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 4/14/2008 Male 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Orchitis Other Serious 4/17/2008 Male 5/2/2008 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Abnormal Hospitalization 2/5/2008 Male 5/20/2008 Physician Japan
Primary
Secondary
Concomitant
Ischaemia Other Serious 4/18/2008 76 Male 5/22/2008 Physician Japan
Primary
Secondary
Leukopenia Life Threatening 3/1/2008 Female 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 4/24/2008 Male 6/3/2008 Physician Japan
Primary
Secondary
Small Intestinal Perforation Life Threatening 4/14/2008 Male 6/4/2008 Physician Japan
Primary
Secondary
Concomitant
Bipolar I Disorder Hospitalization 12/5/2007 Female 6/5/2008 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 12/4/2007 Male 6/5/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 5/23/2008 63 Male 132 lb 6/6/2008 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 11/27/2007 Male 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Other Serious 1/22/2008 Male 6/18/2008 Physician Japan
Primary
Secondary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 6/18/2008 Other Health Professional Japan
Primary
Secondary
Pulmonary Thrombosis Death 2/8/2008 Female 124 lb 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 9/2/2007 Female 6/20/2008 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 3/14/2008 Male 7/3/2008 Physician Japan
Primary
Secondary
Neutrophil Count Decreased Hospitalization 7/30/2007 Male 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Intestinal Fistula Life Threatening 9/5/2007 Female 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 4/24/2008 Male 7/12/2008 Physician Japan
Primary
Secondary
Tumour Haemorrhage Other Serious 5/26/2008 28 Male 121 lb 7/15/2008 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Enterocutaneous Fistula Other Serious 6/1/2008 Male 79 lb 7/18/2008 Physician Japan
Primary
Secondary
Concomitant
Prinzmetal Angina Other Serious 12/9/2007 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/21/2008 Male 139 lb 7/24/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/1/2008 Male 132 lb 7/28/2008 Physician Japan
Primary
Secondary
Concomitant
Nausea Life Threatening 6/25/2008 Female 118 lb 7/28/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening 12/15/2007 Female 7/29/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Life Threatening Female 104 lb 8/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 3/13/2008 Female 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 10/18/2007 Male 8/6/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/14/2008 58 Male 8/7/2008 Physician Japan
Primary
Secondary
Gastrointestinal Perforation Life Threatening 12/15/2007 Female 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 4/24/2008 Male 8/7/2008 Physician Japan
Primary
Secondary
Small Intestinal Perforation Life Threatening 8/1/2008 62 Male 8/14/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 8/4/2008 62 Male 115 lb 8/14/2008 Physician Japan
Primary
Secondary
Shock Other Serious 4/24/2008 Male 8/18/2008 Physician Japan
Primary
Secondary
Nausea Life Threatening 6/25/2008 Female 118 lb 8/18/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 8/1/2008 Male 115 lb 8/20/2008 Physician Japan
Primary
Secondary
Upper Gastrointestinal Haemorrhage Other Serious 10/29/2007 Female 124 lb 8/20/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 5/26/2008 28 Male 121 lb 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 8/10/2008 81 Male 154 lb 8/26/2008 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Life Threatening 7/1/2008 Male 115 lb 8/26/2008 Physician Japan
Primary
Secondary
Bone Marrow Failure Life Threatening 1/4/2008 Female 133 lb 8/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/1/2008 Male 132 lb 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Intervertebral Discitis Hospitalization 4/2/2008 Male 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 8/4/2008 Male 9/8/2008 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 8/6/2008 Male 9/8/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 1/22/2008 Male 148 lb 9/9/2008 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 8/27/2008 Female 100 lb 9/15/2008 Physician Japan
Primary
Secondary
Haemorrhage Subcutaneous Hospitalization 1/9/2008 Male 9/16/2008 Physician Japan
Primary
Secondary
Ileal Perforation Life Threatening 8/1/2008 Male 115 lb 9/16/2008 Physician Japan
Primary
Secondary
Anaphylactic Shock Other Serious 9/1/2008 67 Female 9/17/2008 Physician United Kingdom
Primary
Secondary
Interstitial Lung Disease Hospitalization 4/16/2008 Male 9/22/2008 Physician Japan
Primary
Secondary
Ileal Perforation Death 8/1/2008 Male 121 lb 9/24/2008 Physician Japan
Primary
Secondary
Small Intestinal Perforation Death 7/1/2008 62 Male 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Mucosal Haemorrhage Hospitalization 12/9/2007 Male 157 lb 9/30/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 9/5/2008 Male 10/1/2008 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/22/2008 60 Male 10/6/2008 Physician Japan
Primary
Secondary
Ileal Perforation Death 8/1/2008 Male 121 lb 10/6/2008 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/23/2008 Male 10/17/2008 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Death 9/24/2008 Male 120 lb 10/17/2008 Physician Japan
Primary
Secondary
Generalised Erythema Other Serious 6/20/2008 10/24/2008 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 7/30/2007 Male 10/29/2008 Physician Japan
Primary
Secondary
Concomitant
Enterocutaneous Fistula Other Serious 6/1/2008 Male 79 lb 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 7/26/2007 Female 118 lb 10/31/2008 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Perforation Life Threatening 11/27/2007 Male 132 lb 11/3/2008 Physician Japan
Primary
Secondary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 11/3/2008 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 6/16/2008 Female 11/4/2008 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 10/15/2008 Male 132 lb 11/4/2008 Consumer Japan
Primary
Concomitant
Disease Progression Death 6/12/2008 Female 100 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 1/1/2008 Male 154 lb 11/6/2008 Physician Japan
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 5/1/2008 Male 154 lb 11/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 5/8/2008 Female 157 lb 11/10/2008 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 11/6/2008 59 Male 11/19/2008 Physician United Kingdom
Primary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 11/19/2008 Physician Japan
Primary
Secondary
Anaphylactic Shock Hospitalization 9/1/2008 Female 11/20/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 11/1/2008 63 Female 11/21/2008 Physician United Kingdom
Primary
Secondary
Nausea Life Threatening 6/25/2008 Female 107 lb 11/25/2008 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 11/11/2008 Female 108 lb 11/25/2008 Physician United Kingdom
Primary
Concomitant
Small Intestinal Perforation Death 7/1/2008 Male 12/2/2008 Physician Japan
Primary
Secondary
Concomitant
Hallucination Hospitalization 11/15/2008 Female 93 lb 12/2/2008 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 5/23/2008 Male 141 lb 12/3/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Disease Progression Life Threatening 9/5/2008 Male 12/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Spinal Cord Infarction Hospitalization 11/27/2008 12/12/2008 Physician Japan
Primary
Secondary
Sudden Death Death 10/31/2008 67 Male 12/15/2008 Physician Japan
Primary
Secondary
Varices Oesophageal Other Serious 8/20/2008 Male 12/16/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Peritonitis Other Serious 5/7/2008 70 Female 12/17/2008 Physician Japan
Primary
Secondary
Spinal Cord Infarction Hospitalization 11/27/2008 12/19/2008 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/7/2008 Female 130 lb 12/22/2008 Physician Japan
Primary
Concomitant
Anaphylactic Shock Hospitalization 9/1/2008 Female 12/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 6/4/2008 Female 12/24/2008 Consumer Japan
Primary
Secondary
Pyrexia Other Serious 12/17/2008 59 Female 12/30/2008 Consumer United Kingdom
Primary
Concomitant
Ulcer Disability 6/4/2008 Female 1/2/2009 Physician Japan
Primary
Secondary
Acute Myocardial Infarction Hospitalization 12/11/2008 Male 1/2/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Hospitalization 12/8/2008 49 Male 1/7/2009 Physician Japan
Primary
Secondary
Hepatic Enzyme Increased Hospitalization 8/18/2008 Female 1/7/2009 Pharmacist United Kingdom
Primary
Secondary
Arrhythmia Death 10/31/2008 67 Male 1/8/2009 Physician Japan
Primary
Secondary
Neuropathy Peripheral Hospitalization 10/23/2008 Male 123 lb 1/14/2009 Consumer Japan
Primary
Secondary
Concomitant
Intestinal Perforation Other Serious 61 Female 1/15/2009 Consumer Japan
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/5/2008 Female 1/16/2009 Consumer United Kingdom
Primary
Concomitant
Shock Other Serious 11/6/2008 59 Male 1/23/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/20/2008 Male 110 lb 1/24/2009 Consumer Japan
Primary
Secondary
Concomitant
Shock Hospitalization 12/8/2008 49 Male 1/28/2009 Physician Japan
Primary
Secondary
Concomitant
Gastric Haemorrhage Hospitalization 12/9/2008 69 Male 1/28/2009 Consumer Japan
Primary
Secondary
Interstitial Lung Disease Hospitalization 12/3/2008 74 Male 110 lb 1/29/2009 Consumer Japan
Primary
Concomitant
Rectal Perforation Life Threatening 6/16/2008 Male 2/3/2009 Physician Japan
Primary
Secondary
Concomitant
Hiccups Disability 7/11/2008 Male 143 lb 2/6/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Artery Thrombosis Other Serious 2/20/2008 73 Male 133 lb 2/11/2009 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 11/12/2007 Male 146 lb 2/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoaesthesia Oral Life Threatening 1/15/2008 Male 110 lb 2/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/24/2009 71 Male 2/11/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Ileal Perforation Disability 12/6/2007 Male 117 lb 2/12/2009 Physician Japan
Primary
Secondary
Jejunal Perforation Life Threatening 3/13/2008 Female 105 lb 2/12/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 4/3/2008 Male 2/12/2009 Consumer Japan
Primary
Concomitant
Spinal Cord Infarction Disability 11/25/2008 Male 144 lb 2/12/2009 Physician Japan
Primary
Concomitant
Sepsis Other Serious 11/9/2008 Male 2/13/2009 Consumer Japan
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 1/1/2008 Female 174 lb 2/14/2009 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/3/2009 Male 128 lb 2/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 1/5/2009 Male 2/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Life Threatening 9/5/2008 Male 2/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Perforation Hospitalization 1/20/2009 60 Male 2/20/2009 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Death 1/1/2008 Male 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Life Threatening 1/18/2009 72 Female 2/20/2009 Physician Japan
Primary
Secondary
Shock Other Serious Male 146 lb 2/24/2009 Consumer United Kingdom
Primary
Concomitant
Gastrointestinal Perforation Death 2/2/2009 66 Male 2/25/2009 Physician Japan
Primary
Secondary
Peritonitis Death 12/21/2008 Male 171 lb 2/25/2009 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 11/9/2008 Male 2/26/2009 Consumer Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 12/8/2008 Male 101 lb 2/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 1/24/2009 Male 3/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant

Drug Data