Avastin combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lymphopenia Life Threatening 3/15/2005 56 Female 2/15/2006 Physician United States
Primary
Secondary
Small Intestinal Perforation Hospitalization 10/28/2005 48 Female 3/13/2006 Physician United States
Primary
Secondary
Myocardial Infarction Other Serious 9/12/2005 64 Female 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 4/25/2006 55 6/7/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia 8/1/2005 68 Female 5/31/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Female 178 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/25/2006 45 Female 8/4/2006 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/9/2006 56 Female 8/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/9/2006 56 Female 8/14/2006 United States
Primary
Secondary
Concomitant
Purulent Discharge Hospitalization 7/10/2006 65 Female 375 lb 8/17/2006 Physician United States
Primary
Secondary
Myocardial Infarction Other Serious 9/12/2005 64 Female 6/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 4/20/2006 52 Female 9/14/2006 Other Health Professional United States
Primary
Secondary
Wound Complication Required Intervention 7/17/2006 49 Unknown 9/18/2006 Physician United States
Primary
Secondary
Viral Infection Hospitalization 9/21/2006 38 Female 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/19/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/10/2007 43 Female 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 2/28/2007 66 Female 3/15/2007 Physician United States
Primary
Concomitant
Thrombosis Life Threatening 1/17/2007 71 Female 3/14/2007 Other Health Professional United States
Primary
Secondary
Thrombosis Life Threatening 1/17/2007 71 Female 3/14/2007 Other Health Professional United States
Primary
Secondary
Ejection Fraction Decreased Hospitalization 7/10/2007 51 Female 7/31/2007 Physician United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Life Threatening 7/10/2007 Female 8/16/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Hypertension Death 49 Male 11/10/2007 Physician Switzerland
Primary
Concomitant
Pancreatitis Other Serious 57 Female 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Hypertension Death 49 Male 12/22/2007 Physician Switzerland
Primary
Concomitant
Hypersensitivity Other Serious 3/20/2008 48 Male 302 lb 4/15/2008 Consumer Canada
Primary
Concomitant
Hypersensitivity Other Serious 3/20/2008 48 Male 302 lb 4/22/2008 Consumer Canada
Primary
Concomitant
Febrile Neutropenia Death 5/1/2008 Physician Australia
Primary
Concomitant
Febrile Neutropenia Other Serious 5/1/2008 Physician Australia
Primary
Concomitant
Respiratory Disorder Other Serious 3/20/2008 48 Male 302 lb 5/29/2008 Consumer Canada
Primary
Concomitant
Trismus Other Serious 1/1/2008 Female 7/14/2008 Other Health Professional France
Primary
Concomitant
Gastrointestinal Perforation Death 6/7/2008 Female 9/15/2008 Physician Switzerland
Primary
Concomitant
Pancreatitis Hospitalization 8/13/2008 Female 10/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2008 Female 200 lb 10/8/2008 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 9/1/2008 Female 200 lb 10/10/2008 Pharmacist United States
Primary
Concomitant
Muscle Disorder Other Serious 28 Female 10/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 4/9/2008 Male 10/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Acute Myelomonocytic Leukaemia Death 4/9/2008 Male 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Hypertension Death 65 Female 12/19/2008 United States
Primary
Concomitant
Febrile Neutropenia Other Serious 7/13/2007 Female 121 lb 1/6/2009 Physician Ireland
Primary
Concomitant
Febrile Neutropenia Other Serious 7/13/2007 Female 121 lb 1/26/2009 Physician Ireland
Primary
Concomitant
Proctitis Hospitalization 1/30/2009 74 Female 2/18/2009 Other Health Professional United States
Primary
Secondary
Proctitis Hospitalization 1/30/2009 74 Female 2/18/2009 Other Health Professional United States
Primary
Secondary
Thrombocytopenia Other Serious 1/31/2009 Female 2/27/2009 Consumer United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/2/2009 Female 4/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Other Serious Female 4/24/2009 Consumer United Kingdom
Primary
Secondary
Transaminases Increased Other Serious Female 5/5/2009 Consumer United Kingdom
Primary
Secondary
Temporal Arteritis Hospitalization 3/1/2009 Female 5/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 7/13/2007 Female 121 lb 7/2/2009 Physician Ireland
Primary
Concomitant
Headache Hospitalization 6/19/2009 56 Female 6/26/2009 Pharmacist United States
Primary
Concomitant
Major Depression Hospitalization 8/4/2009 Female 8/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Major Depression Hospitalization 8/4/2009 Female 8/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Enteritis Hospitalization 8/14/2009 Female 8/26/2009 Consumer United Kingdom
Primary
Secondary
Enteritis Hospitalization 8/14/2009 Female 9/10/2009 Consumer United Kingdom
Primary
Secondary
Oesophagitis Hospitalization 8/14/2009 Female 10/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 10/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 10/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/8/2009 Female 11/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 11/2/2009 Female 11/10/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 8/14/2009 Female 11/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 10/8/2009 Female 11/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/14/2009 Male 1/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Proctitis Hospitalization 1/30/2009 74 Female 2/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 11/2/2009 Female 3/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 3/6/2010 55 Female 82 lb 3/31/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombosis In Device Death 1/1/2009 46 Female 4/8/2010 Consumer Netherlands
Primary
Secondary
Lung Adenocarcinoma Metastatic Death 3/31/2010 47 Female 4/9/2010 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/16/2010 United States
Primary
Concomitant
Neutropenic Sepsis Other Serious 11/2/2009 Female 4/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 4/22/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2008 51 Female 4/30/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 7/19/2010 United States
Primary
Concomitant
Vomiting Other Serious 6/30/2010 66 Male 117 lb 7/22/2010 Physician United States
Primary
Secondary
Tooth Abscess Hospitalization 10/1/2009 61 Female 8/12/2010 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 6/30/2010 66 Male 117 lb 8/13/2010 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 10/3/2003 46 Female 128 lb 8/16/2010 United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/24/2010 United States
Primary
Concomitant
Troponin Increased Other Serious 8/25/2010 Physician United States
Primary
Secondary
Vaginal Haemorrhage Other Serious 10/3/2003 46 Female 128 lb 8/31/2010 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/25/2010 69 Female 130 lb 8/31/2010 Other Health Professional United States
Primary
Secondary
Proteinuria Other Serious 7/1/2008 65 Female 9/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 5/31/2010 39 Female 9/24/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 11/14/2010 49 Female 11/22/2010 United States
Primary
Secondary
Oropharyngeal Pain Hospitalization 11/14/2010 49 Female 162 lb 11/15/2010 United States
Primary
Secondary
Concomitant
Radiation Injury Other Serious 2/22/2011 49 Female 155 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Staphylococcal Skin Infection Other Serious 10/3/2003 46 Female 128 lb 3/9/2011 Other Health Professional United States
Primary
Concomitant
Hypercalcaemia Hospitalization 10/3/2003 46 Female 128 lb 4/5/2011 United States
Primary
Concomitant
Jaw Disorder Other Serious 8/1/2010 72 Female 4/6/2011 Physician Germany
Primary
Concomitant
Visual Impairment Other Serious Male 4/28/2011 Consumer United States
Primary
Secondary
Concomitant
Lymphoma Other Serious 1/1/2009 63 Male 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/5/2009 77 Male 179 lb 5/6/2011 Consumer United Kingdom
Primary
Secondary
Ascites Hospitalization 4/10/2008 67 Male 197 lb 5/18/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 9/12/2009 63 Female 92 lb 5/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Pollakiuria Other Serious 7/1/2007 30 Female 6/6/2011 Other Health Professional Portugal
Primary
Secondary
Abdominal Pain Upper Hospitalization 7/6/2007 41 Female 6/14/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 9/1/2009 60 Female 7/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Ankle Fracture Hospitalization 10/3/2003 46 Female 128 lb 7/20/2011 Physician United States
Primary
Concomitant
Haemorrhoids Hospitalization 6/24/2008 58 Female 8/26/2011 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 7/2/2011 64 Female 8/26/2011 Physician United States
Primary
Secondary
Neoplasm Malignant Hospitalization 7/15/2011 49 Female 8/26/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 2/11/2011 55 Female 8/30/2011 Physician United States
Primary
Secondary
Nausea Hospitalization 7/18/2011 38 Female 130 lb 9/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Peritoneum Other Serious 11/1/2009 61 Female 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia 8/4/2009 60 Female 127 lb 10/16/2011 Thailand
Primary
Secondary
Hyperglycaemia Other Serious 3/29/2011 46 Female 227 lb 10/28/2011 Moldova, Republic Of
Primary
Secondary
Anaemia Hospitalization 6/14/2011 50 Female 170 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Anaemia Hospitalization 6/30/2011 39 Female 190 lb 10/31/2011 United States
Primary
Secondary
Otitis Media Hospitalization 7/8/2009 60 Female 176 lb 11/1/2011 Germany
Primary
Secondary
Myalgia Other Serious Female 11/2/2011 United States
Primary
Secondary
Glucose Tolerance Impaired Life Threatening 8/2/2011 59 Female 137 lb 11/3/2011 United States
Primary
Secondary
Diarrhoea Hospitalization 7/8/2011 44 Female 263 lb 11/4/2011 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/30/2011 39 Female 190 lb 11/9/2011 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 6/14/2011 50 Female 170 lb 11/11/2011 United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/7/2010 9 Male 42 lb 11/11/2011 Physician France
Primary
Secondary
Concomitant
Impaired Healing Hospitalization 11/1/2010 49 Female 183 lb 11/14/2011 Physician Austria
Primary
Secondary
Concomitant
Cardiac Disorder Life Threatening 7/8/2011 44 Female 263 lb 11/17/2011 United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 11/17/2011 63 Female 11/28/2011 Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2011 63 Female 12/7/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/20/2011 38 Female 163 lb 12/7/2011 Germany
Primary
Secondary
Concomitant
Breast Cancer Recurrent Other Serious Female 12/23/2011 Physician Ireland
Primary
Secondary
Tachyarrhythmia Hospitalization 8/18/2008 78 Male 198 lb 12/27/2011 Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/20/2011 38 Female 163 lb 12/27/2011 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 7/20/2011 38 Female 163 lb 12/27/2011 Physician Germany
Primary
Secondary
Concomitant
Deep Vein Thrombosis Life Threatening 3/20/2008 67 Male 197 lb 12/29/2011 Australia
Primary
Secondary
Concomitant
Lymphadenopathy Hospitalization 4/7/2011 49 Female 188 lb 1/5/2012 Physician Colombia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2011 63 Female 1/12/2012 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 12/2/2010 40 Female 146 lb 1/13/2012 Germany
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 1/27/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Neutropenia Hospitalization 5/21/2009 57 Female 174 lb 2/13/2012 Australia
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2008 78 Male 198 lb 2/15/2012 Germany
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 1/17/2012 53 Female 227 lb 2/23/2012 Physician Norway
Primary
Secondary
Concomitant
Vascular Access Complication Hospitalization 1/24/2012 28 Female 172 lb 2/23/2012 United States
Primary
Secondary
Abdominal Pain Upper Hospitalization 7/20/2011 38 Female 163 lb 2/24/2012 Germany
Primary
Secondary
Concomitant
Ocular Surface Disease Hospitalization 10/15/2010 58 Female 132 lb 2/28/2012 United States
Primary
Secondary
Post Procedural Haematoma Hospitalization 10/22/2010 7 Male 66 lb 3/7/2012 Physician France
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 1/7/2012 66 Female 119 lb 3/12/2012 Physician Japan
Primary
Secondary
Concomitant
Abscess Jaw Other Serious 65 Female 3/13/2012 Physician Belgium
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 2/21/2012 36 Female 122 lb 3/28/2012 Physician United Kingdom
Primary
Secondary
Rash Hospitalization 1/7/2012 66 Female 119 lb 3/29/2012 Physician Japan
Primary
Secondary
Concomitant
Device Related Infection Hospitalization 1/24/2012 28 Female 172 lb 4/2/2012 United States
Primary
Secondary
Febrile Neutropenia Death 8/30/2009 60 Male 130 lb 4/4/2012 Physician France
Primary
Secondary
Concomitant

Drug Data