Avastin combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Visual Acuity Reduced Other Serious 12/8/2005 79 Female 1/3/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2004 37 Male 225 lb 1/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 59 Male 1/26/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 59 Male 345 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Scab Disability 6/1/2005 71 Male 2/17/2006 Physician United States
Primary
Concomitant
Coagulopathy Required Intervention 2/11/2006 62 Male 191 lb 3/2/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/19/2006 77 Male 215 lb 3/31/2006 United States
Primary
Concomitant
Vomiting Other Serious 2/19/2006 77 Male 215 lb 4/3/2006 United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/6/2006 76 Male 283 lb 4/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/19/2006 77 Male 215 lb 4/7/2006 United States
Primary
Concomitant
Vomiting Other Serious 2/19/2006 77 Male 215 lb 4/12/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/23/2006 70 Female 150 lb 5/5/2006 Physician United States
Primary
Concomitant
Rash Pustular 66 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/26/2004 65 Female 370 lb 5/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 59 Male 346 lb 5/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Sudden Death Death 3/17/2005 56 Male 198 lb 5/25/2006 Physician Canada
Primary
Secondary
Concomitant
Lethargy Required Intervention 1/24/2006 80 Female 157 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Fistula Hospitalization 5/31/2006 57 Female 189 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Required Intervention 5/5/2006 53 Female 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Fistula Hospitalization 5/31/2006 Female 6/27/2006 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Hospitalization 5/31/2006 57 Female 189 lb 6/30/2006 Physician United States
Primary
Secondary
Concomitant
Wound Complication Hospitalization 5/31/2006 Female 7/10/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 60 Female 7/13/2006 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 2/2/2005 71 Female 5/31/2006 Physician United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 5/5/2006 55 Male 5/31/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/1/2005 70 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Hospitalization 79 Male 7/13/2006 Consumer United States
Primary
Concomitant
Skin Ulcer 70 Female 5/31/2006 Physician United States
Primary
Concomitant
Phlebitis Superficial 12/29/2004 71 Female 5/31/2006 Physician United States
Primary
Concomitant
Urticaria 2/1/2006 67 Female 146 lb 8/1/2006 Consumer United States
Primary
Concomitant
Fistula Hospitalization 5/21/2006 Female 114 lb 8/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 4/12/2006 77 Male 205 lb 8/29/2006 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious Male 8/25/2006 Other Health Professional United States
Primary
Concomitant
Trismus Other Serious 6/1/2006 68 Male 150 lb 9/7/2006 United States
Primary
Secondary
Concomitant
Fistula Hospitalization 5/21/2006 Female 114 lb 9/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Trismus Other Serious 6/1/2006 68 Male 150 lb 9/20/2006 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 9/14/2006 52 Female 161 lb 10/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Presyncope Hospitalization 8/10/2006 88 Male 153 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 10/15/2006 Female 11/2/2006 Physician United States
Primary
Secondary
Concomitant
Ectropion Other Serious 10/10/2006 Female 11/10/2006 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 7/1/2005 Male 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 11/8/2006 74 Male 403 lb 11/21/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 10/10/2006 Female 12/11/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/8/2006 74 Male 183 lb 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious Male 12/8/2006 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 11/8/2006 74 Male 12/11/2006 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 62 Male 247 lb 12/14/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
X-ray Gastrointestinal Tract Abnormal Hospitalization 11/8/2006 74 Male 12/19/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/24/2005 70 Male 8/29/2006 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 1/15/2007 Other Health Professional
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 1/22/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Hospitalization 1/2/2007 Female 126 lb 2/5/2007 Other Health Professional
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 1/2/2007 Female 126 lb 2/14/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Hospitalization 1/18/2007 Female 126 lb 2/14/2007 Other Health Professional
Primary
Secondary
Concomitant
Syncope Other Serious 1/18/2007 Female 126 lb 2/19/2007 Other Health Professional
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 1/1/2007 43 Female 184 lb 2/16/2007 Other Health Professional United States
Primary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 2/22/2007 Other Health Professional
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 2/26/2007 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 2/23/2007 Other Health Professional
Primary
Secondary
Concomitant
Disease Progression Death 2/1/2007 Female 161 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious Female 2/20/2007 Pharmacist United States
Primary
Concomitant
Dermatitis Acneiform 70 Male 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/25/2007 55 Female 3/1/2007 Other Health Professional France
Primary
Secondary
Death Death 1/25/2007 55 Female 174 lb 3/8/2007 Consumer France
Primary
Secondary
International Normalised Ratio Increased Hospitalization Unknown 3/8/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 3/8/2007 Pharmacist United States
Primary
Concomitant
Death Death 1/25/2007 55 Female 174 lb 3/21/2007 Other Health Professional France
Primary
Secondary
Haemorrhage Death 1/25/2007 55 Female 174 lb 3/16/2007 Other Health Professional France
Primary
Secondary
Stress Cardiomyopathy Other Serious 11/5/2006 61 Male 160 lb 3/20/2007 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/14/2005 Male 210 lb 3/28/2007 Physician United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/15/2005 82 Female 113 lb 4/6/2007 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 1/25/2007 55 Female 4/18/2007 Other Health Professional France
Primary
Secondary
Death Life Threatening 1/25/2007 55 Female 174 lb 4/20/2007 Consumer France
Primary
Secondary
Death Death 1/25/2007 55 Female 174 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Cardiotoxicity Other Serious 2/19/2007 64 Female 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 2/7/2007 52 Male 4/27/2007 Other Health Professional United States
Primary
Concomitant
Death Life Threatening 1/25/2007 55 Female 174 lb 4/27/2007 Other Health Professional France
Primary
Secondary
International Normalised Ratio Increased Other Serious 2/12/2007 59 Male 4/30/2007 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/8/2007 Female 149 lb 5/1/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 9/19/2006 Female 139 lb 5/29/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/29/2006 54 Female 2/28/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 2/9/2007 Female 7/6/2007 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious 5/1/2007 Female 121 lb 8/15/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Hospitalization 6/19/2007 79 Female 177 lb 10/12/2007 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Hospitalization 6/19/2007 79 Female 177 lb 10/25/2007 Other Health Professional United States
Primary
Concomitant
Fall Other Serious 5/1/2007 Female 121 lb 11/13/2007 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 6/18/2006 Male 11/19/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 115 lb 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 3/3/2008 Female 192 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 10/29/2006 54 Female 2/28/2008 Physician United States
Primary
Concomitant
Haematochezia Hospitalization 3/25/2007 75 Female 131 lb 2/28/2008 Physician United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 66 Female 228 lb 2/28/2008 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 78 Male 2/28/2008 Consumer United States
Primary
Concomitant
Herpes Simplex Hospitalization 3/3/2008 Female 192 lb 5/1/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 4/2/2008 60 Male 5/7/2008 Pharmacist United States
Primary
Concomitant
Retinal Tear Other Serious 9/24/2007 Male 220 lb 5/13/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 62 Female 5/29/2008 Consumer United States
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 5/24/2008 Male 185 lb 6/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/7/2006 Female 115 lb 6/19/2008 Physician United States
Primary
Secondary
Concomitant
Road Traffic Accident Life Threatening 5/24/2008 Male 185 lb 6/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Hospitalization 6/2/2008 74 Female 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2008 Male 224 lb 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2008 Male 224 lb 8/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2008 Male 224 lb 9/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/25/2008 Female 150 lb 9/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Superior Vena Caval Occlusion Hospitalization 2/7/2008 50 Female 128 lb 9/25/2008 Physician United States
Primary
Secondary
Concomitant
Wound Complication Hospitalization 5/31/2006 Male 189 lb 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/30/2008 Female 187 lb 10/24/2008 Consumer United States
Primary
Concomitant
Pain In Jaw Other Serious 4/2/2008 60 Male 9/26/2008 Pharmacist United States
Primary
Concomitant
Disease Progression Other Serious 9/30/2008 Female 187 lb 11/14/2008 Consumer United States
Primary
Concomitant
Vision Blurred Disability 8/1/2008 Male 224 lb 11/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 4/2/2008 Male 12/19/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/16/2007 Female 161 lb 12/26/2008 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/30/2008 Female 187 lb 12/29/2008 Consumer United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 12/30/2008 Male 161 lb 1/14/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/30/2008 63 Male 161 lb 1/16/2009 Pharmacist United States
Primary
Concomitant
Malaise Death 1/28/2009 Female 2/2/2009 Consumer United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 1/1/2009 Female 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Tongue Ulceration 8/5/2008 42 Female 236 lb 3/25/2009 Consumer United States
Primary
Concomitant
Peritonitis Life Threatening 1/18/2007 Female 126 lb 4/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/29/2009 58 Female 280 lb 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 1/2/2007 Female 126 lb 7/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/9/2009 Male 160 lb 8/17/2009 Physician United States
Primary
Concomitant
Renal Haemorrhage Other Serious Male 9/9/2009 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 6/22/2009 Male 141 lb 9/17/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/1/2009 Female 9/25/2009 Consumer United States
Primary
Concomitant
Renal Haemorrhage Hospitalization 57 Male 10/8/2009 Consumer United States
Primary
Secondary
Concomitant
Odynophagia Hospitalization 10/26/2008 Male 154 lb 10/8/2009 Physician United States
Primary
Concomitant
Peripheral Sensorimotor Neuropathy Hospitalization 68 Female 11/11/2009 Physician United States
Primary
Secondary
Concomitant
Skin Hypopigmentation Other Serious 10/30/2009 Male 120 lb 11/19/2009 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Death 1/1/2009 Female 12/1/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2003 Male 12/18/2009 Physician United States
Primary
Concomitant
Skin Hypopigmentation Other Serious 10/30/2009 Male 122 lb 12/28/2009 Consumer United States
Primary
Concomitant
Skin Hypopigmentation 10/30/2009 Male 122 lb 1/8/2010 Consumer United States
Primary
Concomitant
Uterine Cervical Squamous Metaplasia Other Serious 6/26/2006 49 Female 129 lb 1/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 Male 159 lb 1/19/2010 Physician United States
Primary
Concomitant
Urinary Retention Other Serious 1/11/2007 Male 1/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2009 Female 1/28/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2009 Female 2/8/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2009 Female 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2003 Male 159 lb 2/15/2010 Physician United States
Primary
Concomitant
Uterine Cervical Squamous Metaplasia Other Serious 6/26/2006 49 Female 129 lb 2/17/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2006 Female 129 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant

Drug Data