Avastin combined with Cisplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Dysfunction Hospitalization 51 Female 144 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 51 Female 144 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2005 57 Male 1/27/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/7/2006 47 Male 184 lb 3/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 3/6/2006 52 Male 225 lb 3/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain Hospitalization 3/3/2006 62 Female 185 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/6/2006 52 Male 225 lb 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/7/2006 47 Male 184 lb 3/20/2006 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 10/27/2005 67 Male 3/31/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 1/1/2006 58 Female 4/21/2006 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 1/1/2006 58 Female 5/9/2006 Other Health Professional France
Primary
Concomitant
Tachycardia Death 4/17/2006 79 Male 159 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Catheter Related Complication 12/16/2005 62 Male 3/1/2006 Physician United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 11/28/2005 51 Female 144 lb 1/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 11/28/2005 51 Female 144 lb 1/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/7/2006 47 Male 164 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/30/2005 71 Male 265 lb 6/5/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/16/2006 65 Unknown 6/7/2006 Other Health Professional United States
Primary
Secondary
Post Procedural Urine Leak Hospitalization 6/6/2006 48 Female 6/21/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 6/23/2006 48 Male 192 lb 7/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Anastomotic Leak Hospitalization 6/6/2006 48 Female 7/7/2006 Physician United States
Primary
Concomitant
Mucosal Inflammation Other Serious 12/16/2005 Male 388 lb 7/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphonia 3/31/2006 Female 5/31/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/26/2006 51 7/19/2006 Physician United States
Primary
Secondary
Tachycardia Death 4/17/2006 79 Male 159 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/30/2006 70 Female 8/2/2006 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 4/16/2006 65 8/15/2006 Other Health Professional United States
Primary
Secondary
Platelet Count Decreased Hospitalization 7/25/2006 68 Male 186 lb 8/15/2006 Physician United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/30/2006 70 Female 8/18/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/13/2006 53 Male 8/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/25/2006 66 Unknown 8/17/2006 Physician United States
Primary
Secondary
Staphylococcal Infection Hospitalization 8/7/2006 55 Male 170 lb 8/22/2006 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 8/13/2006 68 Male 180 lb 8/28/2006 Physician United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 6/30/2006 70 Female 8/30/2006 Physician Switzerland
Primary
Secondary
Concomitant
Death Death 8/16/2006 74 Male 108 lb 9/8/2006 Physician Brazil
Primary
Secondary
Radiation Injury Hospitalization 9/21/2006 47 Male 150 lb 10/3/2006 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 9/30/2006 41 Male 10/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 9/12/2006 47 Male 150 lb 10/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/30/2006 41 Male 10/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/7/2006 47 Male 184 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 68 Male 180 lb 11/28/2006 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Required Intervention Male 12/6/2006 Physician Philippines
Primary
Concomitant
Waist Circumference Increased Death 11/22/2006 84 Male 200 lb 12/15/2006 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 12/13/2006 79 Female 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 11/15/2006 84 Male 200 lb 12/28/2006 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 12/13/2006 79 Female 1/9/2007 Physician United States
Primary
Secondary
Concomitant
Ileus Hospitalization 12/22/2006 Male 179 lb 1/11/2007 Consumer United States
Primary
Secondary
Concomitant
Urine Sodium Decreased Hospitalization 12/23/2006 53 Male 179 lb 1/10/2007 Physician Australia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/13/2006 53 Male 1/17/2007 Other Health Professional United States
Primary
Secondary
Stomatitis Hospitalization 12/21/2006 59 Male 1/19/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/10/2007 Female 137 lb 1/24/2007 Other Health Professional United States
Primary
Secondary
Acute Respiratory Distress Syndrome Required Intervention Male 1/27/2007 Physician Philippines
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/1/2006 68 Male 180 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 70 Female 2/26/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/3/2007 77 Female 163 lb 3/15/2007 Physician United States
Primary
Secondary
Hypertensive Crisis Other Serious 68 Male 3/21/2007 Physician United States
Primary
Concomitant
Hypertensive Crisis Other Serious 68 Male 3/26/2007 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 1/1/2006 59 124 lb 4/5/2007 Physician United States
Primary
Concomitant
X-ray Abnormal Other Serious 9/1/2006 59 Female 124 lb 4/18/2007 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 3/4/2007 Female 160 lb 5/19/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious 70 Female 2/28/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 12/11/2006 53 Female 6/8/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 6/12/2007 United States
Primary
Concomitant
Splenomegaly Other Serious 3/4/2007 Female 160 lb 6/22/2007 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 7/26/2007 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/5/2007 77 Male 178 lb 7/28/2007 United States
Primary
Concomitant
Stomatitis Other Serious 4/15/2007 77 Male 178 lb 8/2/2007 Physician United States
Primary
Concomitant
Cerebral Infarction Other Serious 9/6/2007 Male 201 lb 9/24/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 9/6/2007 Male 201 lb 10/1/2007 Consumer United States
Primary
Secondary
Concomitant
Sudden Onset Of Sleep Death Male 229 lb 11/27/2007 Pharmacist United States
Primary
Concomitant
Haemoglobinaemia Hospitalization 11/23/2007 Male 142 lb 12/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 11/23/2007 Male 142 lb 12/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 71 Male 141 lb 12/18/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/1/2008 64 Male 2/14/2008 Physician France
Primary
Concomitant
Pyrexia Other Serious 1/1/2008 48 Male 2/19/2008 Consumer United States
Primary
Concomitant
Renal Failure Other Serious Female 2/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 9/25/2007 50 Female 1/18/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia 4/7/2007 Female 3/28/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 2/19/2008 Female 4/10/2008 Physician United Kingdom
Primary
Concomitant
Hypertensive Encephalopathy Death 2/22/2007 68 Male 2/28/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 12/5/2006 70 Female 2/28/2008 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 10/10/2007 69 Male 225 lb 2/28/2008 Other Health Professional United States
Primary
Secondary
Haemoptysis Death Female 2/28/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 2/1/2008 Male 5/12/2008 Physician France
Primary
Concomitant
Death Death 2/17/2008 Male 5/23/2008 Other Health Professional France
Primary
Concomitant
Therapeutic Response Delayed Other Serious 1/1/1999 Female 145 lb 7/3/2008 Consumer United States
Primary
Concomitant
Shock Haemorrhagic Death 12/17/2007 52 Female 7/15/2008 Physician United Kingdom
Primary
Concomitant
Atrial Fibrillation Hospitalization 2/6/2008 Male 7/18/2008 Physician United Kingdom
Primary
Secondary
Skin Swelling 12/10/2007 Male 122 lb 7/25/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/15/2008 Female 8/15/2008 Consumer United States
Primary
Concomitant
Penile Ulceration Other Serious Male 8/29/2008 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/15/2008 Female 156 lb 9/2/2008 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Other Serious 7/31/2008 55 Male 9/3/2008 United States
Primary
Concomitant
Nausea Hospitalization 60 Female 9/12/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Delayed Other Serious 1/1/1999 Female 155 lb 9/24/2008 Physician United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 2/18/2008 Male 176 lb 10/2/2008 Physician United Kingdom
Primary
Concomitant
Death Death 9/21/2008 77 Male 86 lb 10/3/2008 Physician United Kingdom
Primary
Secondary
Death Death 7/28/2008 Male 10/3/2008 Physician United Kingdom
Primary
Secondary
Death Death 1/30/2008 Male 10/3/2008 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 3/6/2006 Male 225 lb 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Muscle Disorder Other Serious 28 Female 10/15/2008 Physician Sweden
Primary
Secondary
Concomitant
Penile Ulceration Other Serious 7/24/2008 Male 10/22/2008 Physician United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 7/8/2008 75 Male 165 lb 10/27/2008
Primary
Secondary
Concomitant
Penile Ulceration Other Serious 7/24/2008 Male 11/7/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 10/30/2008 65 Male 172 lb 11/7/2008 Consumer United States
Primary
Secondary
Rash Erythematous 9/4/2008 Female 11/14/2008 Consumer United States
Primary
Concomitant
Leukoencephalopathy Hospitalization 7/8/2008 Male 11/25/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 7/31/2008 55 Male 12/5/2008 Pharmacist United States
Primary
Concomitant
Pupil Fixed Death 12/1/2008 69 Male 197 lb 12/9/2008 Other Health Professional United States
Primary
Secondary
Pain In Jaw Other Serious 4/2/2008 Male 12/19/2008 Pharmacist United States
Primary
Concomitant
Motor Dysfunction Hospitalization 8/27/2008 Female 12/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Motor Dysfunction Hospitalization 1/24/2008 Male 1/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 9/9/2008 60 Female 245 lb 1/14/2009 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/16/2008 Female 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Metastases To Bone Other Serious Male 1/15/2009 Physician United Kingdom
Primary
Concomitant
Motor Dysfunction Hospitalization 8/27/2008 Female 1/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 Male 1/23/2009 Physician France
Primary
Concomitant
Monoparesis Hospitalization 10/27/2008 Male 1/28/2009 Physician United Kingdom
Primary
Secondary
Vasogenic Cerebral Oedema Hospitalization 12/7/2008 61 Female 138 lb 2/2/2009 United States
Primary
Secondary
Thrombotic Microangiopathy Death 9/18/2008 Male 2/4/2009 Physician United Kingdom
Primary
Secondary
Encephalopathy Disability 2/6/2009 Physician United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 12/16/2008 Female 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Nasal Septum Perforation Disability 2/13/2009 41 Female 167 lb 3/4/2009 Pharmacist United States
Primary
Concomitant
Rash Hospitalization Male 3/24/2009 Physician United Kingdom
Primary
Secondary
Polyneuropathy Hospitalization 4/10/2008 67 Male 3/25/2009 Physician United Kingdom
Primary
Secondary
Flushing Other Serious 3/5/2009 58 Male 4/10/2009 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 4/21/2009 Consumer United Kingdom
Primary
Secondary
Chills Hospitalization 1/1/2009 Male 5/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Death 1/1/2008 59 Male 5/6/2009 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 1/1/2008 Male 5/14/2009 Physician France
Primary
Concomitant
Xerophthalmia Other Serious 5/19/2009 Consumer United Kingdom
Primary
Secondary
Polyneuropathy Hospitalization 4/10/2008 67 Male 5/26/2009 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 62 Male 6/12/2009 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2008 Female 136 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 11/1/2008 67 Female 7/2/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 3/5/2009 58 Male 7/23/2009 Consumer United Kingdom
Primary
Concomitant
Thrombophlebitis Hospitalization 12/26/2008 57 8/6/2009 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 7/5/2009 72 Male 164 lb 8/7/2009 Other Health Professional Israel
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 12/26/2008 Male 8/7/2009 Consumer France
Primary
Secondary
Tooth Extraction Other Serious 12/11/2006 Female 9/1/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/11/2006 Female 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 9/28/2008 Female 9/16/2009 Consumer United States
Primary
Concomitant
Status Epilepticus Life Threatening 9/28/2008 Female 9/18/2009 Consumer United States
Primary
Concomitant
Congestive Cardiomyopathy Death Male 9/22/2009 Consumer United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 6/30/2009 Male 9/29/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Status Epilepticus Life Threatening 9/28/2008 Female 9/29/2009 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 6/30/2009 Male 10/1/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death Male 10/1/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Embolism Life Threatening 9/15/2009 Female 186 lb 9/29/2009 Other Health Professional United States
Primary
Secondary

Drug Data