Avandia combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Analysis Abnormal Other Serious 10/30/2005 Female 194 lb 1/4/2006 United States
Primary
Concomitant
Thirst Other Serious 12/1/2004 58 Female 1/5/2006 United States
Primary
Concomitant
Device Malfunction Other Serious 10/13/2005 58 Female 1/6/2006 Consumer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2003 59 Male 1/10/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2004 55 Male 1/10/2006 Consumer United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 6/1/2005 44 Female 197 lb 1/10/2006 Physician Ireland
Primary
Concomitant
Device Failure Other Serious 10/13/2005 58 Female 1/10/2006 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Disability 1/1/2002 69 Male 1/11/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Disability 78 Male 1/12/2006 Consumer United States
Primary
Concomitant
Venous Occlusion Other Serious 1/26/2002 61 Female 185 lb 1/13/2006 Lawyer United States
Primary
Concomitant
Hypoglycaemia Hospitalization 2/29/2004 68 Female 6/30/2005 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 1/1/2004 53 Female 220 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/12/2006 58 Male 300 lb 1/12/2006 Pharmacist United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/26/2002 61 Female 185 lb 1/23/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/15/2005 31 Female 210 lb 1/20/2006 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 1/1/2005 Male 1/27/2006 Physician Canada
Primary
Concomitant
Swelling Other Serious Male 1/30/2006 Physician Canada
Primary
Secondary
Concomitant
Creatinine Renal Clearance Increased Other Serious Male 2/1/2006 Physician Canada
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/1/2005 51 Male 2/2/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2006 77 Male 2/3/2006 Physician United States
Primary
Concomitant
Intraocular Pressure Test Other Serious Male 2/6/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 6/14/2002 58 Male 260 lb 2/14/2006 Lawyer United States
Primary
Concomitant
Swelling Other Serious 1/1/2001 62 Male 2/15/2006 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation Hospitalization 80 Male 2/16/2006 Consumer United States
Primary
Concomitant
Dysgeusia 12/3/2005 76 Female 130 lb 1/5/2006 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious 1/1/2003 75 Female 201 lb 2/23/2006 Physician United States
Primary
Concomitant
Uterine Leiomyoma Hospitalization 1/24/2006 49 Female 2/15/2006 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 2/3/2006 53 Female 345 lb 2/15/2006 Physician United States
Primary
Secondary
Concomitant
No Adverse Effect Hospitalization 1/1/2006 Male 201 lb 3/1/2006 Consumer United States
Primary
Secondary
Concomitant
Erectile Dysfunction 8/10/2005 48 Male 12/30/2005 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2004 78 Male 3/6/2006 Consumer United Kingdom
Primary
Concomitant
Night Blindness Other Serious 79 Female 3/6/2006 Consumer United Kingdom
Primary
Concomitant
Oesophageal Carcinoma Other Serious 56 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 60 Female 3/7/2006 Physician Australia
Primary
Concomitant
Weight Increased Life Threatening 60 Female 3/7/2006 Physician Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/21/2006 80 Female 3/10/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 1/1/2001 61 Male 2/27/2006 Physician Canada
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 55 Female 3/13/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/29/2006 70 Female 250 lb 3/8/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 1/21/2005 60 Male 363 lb 3/14/2006 Physician Canada
Primary
Concomitant
Pneumonia Hospitalization 10/30/2005 59 Male 212 lb 3/15/2006 Physician Belgium
Primary
Concomitant
Vomiting 1/1/2005 71 Female 193 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 9/1/2005 74 Male 177 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 11/18/2005 59 Female 140 lb 1/20/2006 Consumer United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Visual Field Defect 12/1/2005 51 Male 185 lb 1/20/2006 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/23/2006 80 Female 3/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/27/2005 76 Female 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased 11/5/2005 64 Male 260 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/13/2006 Male 3/13/2006 Consumer United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 3/1/2003 47 Male 3/21/2006 Consumer United States
Primary
Concomitant
Vitreous Floaters Other Serious 11/1/2005 80 Female 100 lb 3/21/2006 Physician Canada
Primary
Concomitant
Cataract Other Serious 63 Female 3/21/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Other Serious Female 3/22/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2005 51 Male 210 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 9/13/2005 57 Female 250 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/3/2005 66 Female 214 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 9/30/2005 61 Female 154 lb 1/20/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 53 Female 220 lb 3/24/2006 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/13/2006 57 Male 239 lb 3/28/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2002 57 Female 3/28/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 3/2/2004 45 Male 196 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Nausea 11/8/2005 58 Male 252 lb 1/20/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 1/1/2005 59 Male 1/20/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 9/1/2005 59 Female 218 lb 1/20/2006 Consumer United States
Primary
Concomitant
Portal Hypertensive Gastropathy Hospitalization 1/1/2006 62 Female 3/29/2006 Consumer Denmark
Primary
Concomitant
Overdose Hospitalization 3/1/2003 60 Male 231 lb 3/30/2006 Lawyer United States
Primary
Concomitant
Vomiting 11/14/2005 66 Female 1/20/2006 Consumer United States
Primary
Concomitant
Energy Increased 10/17/2005 67 Female 200 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting 11/24/2005 61 Female 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Nausea 11/11/2005 72 Female 136 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/1/2005 68 Male 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/1/2005 58 Male 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/19/2005 59 Male 314 lb 1/20/2006 Consumer United States
Primary
Concomitant
Decreased Appetite 11/20/2005 57 Male 214 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 83 Female 160 lb 1/20/2006 Consumer United States
Primary
Concomitant
Medication Error 11/15/2005 54 Female 1/20/2006 Consumer United States
Primary
Concomitant
Decreased Appetite 1/1/2005 63 Male 243 lb 1/20/2006 Consumer United States
Primary
Concomitant
Abdominal Pain 11/16/2005 39 Female 265 lb 1/20/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 10/27/2005 75 Male 270 lb 1/20/2006 Consumer United States
Primary
Concomitant
Sinus Congestion 9/15/2005 59 Female 180 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/21/2005 68 Female 128 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/1/2005 67 Female 181 lb 1/20/2006 United States
Primary
Concomitant
Blood Glucose Increased 10/19/2005 43 Male 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Drug Effect Decreased 10/15/2005 56 Male 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 7/24/2005 56 Female 181 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 11/16/2005 55 Female 305 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 10/16/2005 65 Female 156 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/29/2005 46 Male 212 lb 1/20/2006 Consumer United States
Primary
Concomitant
Decreased Appetite 10/28/2005 59 Female 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/2/2005 57 Female 231 lb 1/20/2006 Consumer United States
Primary
Concomitant
Faeces Discoloured 11/7/2005 54 Female 255 lb 1/20/2006 Consumer United States
Primary
Concomitant
Visual Disturbance 11/1/2005 66 Male 170 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/26/2005 65 Male 243 lb 1/20/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 8/30/2004 70 Male 4/5/2006 Physician Australia
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 12/9/2003 61 Female 4/5/2006 Consumer France
Primary
Secondary
Weight Decreased 10/28/2005 59 Male 169 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting 11/11/2005 46 Female 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 11/19/2005 54 Female 238 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Urticaria 11/14/2005 55 Female 182 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Increased 11/11/2005 59 Female 274 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2003 67 Female 190 lb 4/6/2006 Physician United States
Primary
Concomitant
No Adverse Effect Hospitalization 1/1/2006 Male 201 lb 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Decreased 10/10/2005 61 Female 228 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/8/2005 76 Female 1/20/2006 Consumer United States
Primary
Concomitant
Alopecia 10/1/2005 48 Female 270 lb 1/20/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 11/1/2005 67 Male 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Pain 11/1/2005 35 Female 245 lb 1/20/2006 Consumer United States
Primary
Concomitant
Retching 10/14/2005 44 Female 238 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 7/1/2005 48 Male 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 9/1/2005 53 Male 275 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 11/17/2005 71 Female 160 lb 1/20/2006 Consumer United States
Primary
Concomitant
Pyrexia 11/11/2005 56 Female 200 lb 1/20/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 85 Female 4/7/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 9/1/2005 64 Female 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 10/2/2005 66 Male 1/20/2006 Consumer United States
Primary
Concomitant
Medication Error 10/2/2005 64 Female 225 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 12/1/2005 50 Male 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2005 67 Male 190 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting 9/1/2005 Female 1/20/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 12/22/2005 50 Female 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 12/1/2005 61 Female 138 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vomiting 12/1/2005 84 Female 196 lb 1/20/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 11/9/2005 71 Male 1/20/2006 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 3/16/2006 Female 250 lb 4/10/2006 Consumer
Primary
Concomitant
Vomiting 12/14/2005 65 Male 217 lb 1/20/2006 Consumer United States
Primary
Concomitant
Tremor 1/1/2005 80 Male 207 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2005 52 Female 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 9/17/2005 54 Female 229 lb 1/20/2006 Consumer United States
Primary
Concomitant
Medication Error 10/8/2005 64 Female 285 lb 1/20/2006 Other Health Professional United States
Primary
Concomitant
Medication Error 12/1/2005 52 Female 193 lb 1/20/2006 Consumer United States
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 71 Male 4/11/2006 Physician Belgium
Primary
Concomitant
Oesophageal Carcinoma Other Serious 2/1/2006 56 Male 244 lb 3/28/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2005 64 Male 203 lb 1/20/2006 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 12/1/2005 53 Female 175 lb 1/20/2006 Consumer United States
Primary
Concomitant
Retching 12/1/2005 59 Female 260 lb 1/20/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia 12/12/2005 57 Male 315 lb 1/20/2006 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/10/2006 39 Female 4/12/2006 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 71 Male 4/13/2006 Physician Belgium
Primary
Concomitant
Myocardial Infarction Other Serious 5/1/2005 53 Male 2/2/2006 United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2005 60 Female 203 lb 4/14/2006 Physician Australia
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 10/13/2005 58 Female 4/14/2006 Consumer United States
Primary
Secondary
Concomitant
Arterial Occlusive Disease Other Serious 1/1/2004 66 Female 4/6/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 85 Female 4/17/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Pain Hospitalization 1/1/1998 Male 140 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Required Intervention 3/14/2006 54 Male 160 lb 4/13/2006 Other Health Professional United States
Primary
Concomitant
Vitreous Haemorrhage Other Serious 1/26/2002 61 Female 185 lb 4/19/2006 Physician United States
Primary
Concomitant
Spinal Compression Fracture Other Serious 8/1/2005 64 Male 2/17/2006 Physician United States
Primary
Concomitant

Drug Data