Avandia combined with Coumadin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Other Serious 1/1/2000 71 Male 201 lb 1/3/2006 Lawyer United States
Primary
Concomitant
Prostate Cancer Hospitalization 1/1/2000 57 Male 260 lb 1/6/2006 Lawyer United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2005 66 Male 1/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 76 Female 1/19/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 7/1/2005 Male 286 lb 1/25/2006 Consumer United States
Primary
Secondary
Concomitant
Eye Swelling Other Serious 1/1/2006 87 Female 1/31/2006 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2005 Male 2/1/2006 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 10/6/2005 71 Male 2/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2005 71 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Depression 5/1/2005 47 Female 2/8/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 7/1/2005 Male 286 lb 2/15/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/11/2003 46 Female 280 lb 2/16/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 11/1/2002 53 Male 214 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Hypovolaemia Hospitalization 10/6/2005 71 Male 2/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 10/12/2003 Male 286 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/6/2003 70 Male 209 lb 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Medication Error 12/23/2005 United States
Primary
Secondary
Renal Failure Acute Hospitalization 9/6/2003 70 Male 209 lb 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced 73 Male 12/7/2005 Consumer United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 1/1/2005 76 Female 170 lb 3/10/2006 United States
Primary
Concomitant
Peripheral Vascular Disorder Other Serious 1/1/2000 68 Male 201 lb 3/24/2006 Physician United States
Primary
Concomitant
Weight Decreased 10/20/2005 74 Female 142 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 11/17/2005 74 Male 230 lb 1/20/2006 Consumer United States
Primary
Concomitant
Oedema 6/21/2005 50 Female 252 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 9/1/2005 64 Male 217 lb 1/20/2006 Consumer United States
Primary
Concomitant
Overdose Other Serious 10/14/2005 75 Female 4/11/2006 Consumer France
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/6/2002 53 Male 214 lb 4/13/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/6/2003 70 Male 201 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 8/1/2005 64 Male 2/17/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2005 67 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/12/2005 67 Male 2/17/2006 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/1/2001 51 Female 231 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Therapy Non-responder Life Threatening 4/12/2006 71 Female 271 lb 5/26/2006 Canada
Primary
Concomitant
Blood Glucose Increased 3/6/2006 80 Male 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/17/2006 69 Female 247 lb 5/31/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Facial 50 Female 247 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Troponin Hospitalization 69 Female 276 lb 6/16/2006 Physician Canada
Primary
Concomitant
Blood Glucose Increased 3/11/2006 80 Male 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/11/2006 47 Female 133 lb 6/21/2006 Other Health Professional United States
Primary
Concomitant
Swelling 9/11/2003 79 Female 7/21/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 83 Male 7/21/2006 Consumer United States
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Female 7/21/2006 Consumer United States
Primary
Concomitant
Rash 5/29/2005 67 Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Male 7/21/2006 Consumer United States
Primary
Concomitant
Weight Loss Poor 68 Female 281 lb 7/21/2006 Consumer United States
Primary
Concomitant
Glycosylated Haemoglobin Increased 1/5/2006 80 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Female 7/21/2006 Consumer United States
Primary
Concomitant
Weight Increased 39 Female 7/21/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 77 Male 7/21/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral 72 Male 7/21/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Abnormal 6/8/2004 64 Female 223 lb 8/1/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/1/2005 56 Male 249 lb 8/1/2006 Consumer United States
Primary
Concomitant
Pain Of Skin Other Serious 3/19/2004 77 Male 240 lb 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Drug Dispensing Error 8/1/2006 Pharmacist United States
Primary
Secondary
Diabetes Mellitus 3/1/2005 38 Female 265 lb 8/1/2006 Consumer United States
Primary
Concomitant
Weight Decreased 10/1/2005 74 Female 141 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 8/4/2006 Male 230 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/1/2006 Female 326 lb 8/24/2006 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 8/3/2006 74 Male 8/18/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 4/10/2006 63 Female 190 lb 8/29/2006 United States
Primary
Secondary
Concomitant
Injection Site Pruritus 4/18/2006 67 Male 7/21/2006 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 5/1/2006 72 Male 9/5/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 5/1/2006 72 Male 9/29/2006 United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 3/1/2006 50 Male 216 lb 10/13/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 10/15/2006 69 Male 10/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 10/15/2006 69 Male 10/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/1/2006 68 Female 10/20/2006 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 10/15/2006 69 Male 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 6/1/2006 81 Male 11/13/2006 Consumer United States
Primary
Concomitant
Erectile Dysfunction Other Serious 10/15/2006 69 Male 11/21/2006 Physician United States
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 10/15/2006 69 Male 11/29/2006 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 8/1/2006 68 Female 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Disability 8/1/2006 90 Female 12/13/2006 Consumer United States
Primary
Concomitant
Renal Infarct Other Serious 7/6/2006 54 Female 175 lb 12/20/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 12/14/2006 77 Male 12/26/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/28/2006 Consumer United States
Primary
Concomitant
Rash Hospitalization 7/14/2006 81 Male 212 lb 12/28/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 12/7/2006 73 Female 185 lb 12/19/2006 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 8/14/2006 Female 199 lb 1/10/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased Required Intervention 7/7/2006 Female 10/25/2006 Consumer United States
Primary
Concomitant
Atrial Fibrillation 7/1/2006 50 Male 10/16/2006 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Life Threatening 4/12/2006 72 Female 271 lb 1/26/2007 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/4/2006 3/26/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Life Threatening 4/12/2006 72 Female 271 lb 1/29/2007 Physician Canada
Primary
Concomitant
Injection Site Bruising Other Serious 1/1/2006 77 Female 2/1/2007 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 69 Female 2/13/2007 Consumer United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 1/1/1997 77 Female 188 lb 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 5/1/2006 69 Male 250 lb 10/16/2006 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/8/2007 Male 160 lb 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 12/7/2006 73 Female 185 lb 2/8/2007 Consumer United States
Primary
Concomitant
Injection Site Bruising Other Serious 1/1/2006 77 Female 2/23/2007 Consumer United States
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 12/1/2006 Female 3/14/2007 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 4/1/2005 79 Female 162 lb 2/23/2006 United States
Primary
Concomitant
Blood Creatinine Increased Required Intervention 79 Female 8/19/2005 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/13/2006 Male 3/30/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 64 Male 246 lb 1/12/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 7/12/2006 Male 4/17/2007 Physician
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 87 Female 5/3/2007 Consumer United States
Primary
Concomitant
Flatulence 10/1/2006 61 Male 2/16/2007 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 12/16/2005 75 Female 165 lb 2/21/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Hospitalization 2/26/2006 58 Male 5/22/2007 Lawyer United States
Primary
Concomitant
Injection Site Bruising Other Serious 1/1/2006 77 Female 5/21/2007 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 10/1/2006 68 Male 5/31/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 3/1/2007 78 Female 6/7/2007 Consumer United States
Primary
Concomitant
Dysgeusia 82 Male 5/17/2007 Pharmacist United States
Primary
Concomitant
Vertigo Other Serious 12/15/2006 Male 188 lb 6/18/2007 Physician United States
Primary
Concomitant
Pericardial Effusion Other Serious 10/1/2006 68 Male 6/18/2007 Consumer United States
Primary
Concomitant
Weight Decreased 3/7/2007 69 Female 210 lb 4/10/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2005 82 Male 6/19/2007 Consumer United States
Primary
Concomitant
Muscle Rigidity Hospitalization 6/12/2007 55 Female 218 lb 6/15/2007 Pharmacist United States
Primary
Concomitant
Weight Loss Poor Hospitalization 69 Female 271 lb 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 6/14/2007 36 Male 6/21/2007 Consumer United States
Primary
Concomitant
Brain Neoplasm Death Male 300 lb 6/22/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Vomiting Other Serious 5/11/2007 60 Male 6/28/2007 Consumer United States
Primary
Concomitant
Swelling Other Serious Female 7/5/2007 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 41 Male 7/6/2007 Consumer United States
Primary
Concomitant
Medication Error 7/23/2007 Pharmacist United States
Primary
Secondary
Blood Glucose Increased Male 7/23/2007 Consumer United States
Primary
Concomitant
Nausea Male 7/23/2007 Consumer United States
Primary
Concomitant
Orthopnoea Life Threatening 6/26/2006 73 Male 190 lb 7/23/2007 Physician Canada
Primary
Concomitant
Drug Ineffective 74 Male 7/23/2007 Consumer United States
Primary
Concomitant
Weight Increased 73 Male 7/23/2007 Consumer United States
Primary
Concomitant
Insulin Resistance Hospitalization 56 Male 7/23/2007 Consumer United States
Primary
Concomitant
Skin Warm 9/19/2006 74 Female 7/23/2007 Consumer United States
Primary
Concomitant
Sinus Operation 3/1/2006 Male 7/23/2007 Consumer United States
Primary
Concomitant
Blood Cholesterol Increased 12/1/2006 63 Male 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Disability 58 Male 327 lb 7/23/2007 Consumer United States
Primary
Concomitant
Weight Increased 86 Female 7/23/2007 Consumer United States
Primary
Concomitant
Arrhythmia 6/1/2006 65 Male 7/23/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 6/25/2006 Female 8/15/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/21/2007 84 Male 8/15/2007 Consumer United States
Primary
Concomitant
Muscle Haemorrhage Hospitalization 12/30/2006 Male 214 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 68 Female 160 lb 8/20/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Discomfort 3/19/2007 73 Male 7/11/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/21/2007 84 Male 9/13/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/21/2007 84 Male 9/21/2007 Consumer United States
Primary
Concomitant
Medication Residue 4/17/2007 67 Female 8/16/2007 United States
Primary
Concomitant
Pitting Oedema Hospitalization 6/21/2007 84 Male 9/26/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 2/13/2007 Female 8/16/2007 Physician United States
Primary
Concomitant
Eye Irritation 5/31/2007 82 Female 7/5/2007 Consumer United States
Primary
Concomitant
Eye Pain 5/31/2007 81 Female 7/5/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 262 lb 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Urostomy Complication Hospitalization 11/3/2004 60 Male 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Renal Infarct Other Serious 7/6/2006 54 Female 175 lb 10/16/2007 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered Hospitalization 10/16/2007 Male 289 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Life Threatening 8/16/2007 65 Male 293 lb 11/8/2007 Physician Canada
Primary
Concomitant
Visual Disturbance 80 Female 11/12/2007 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Decreased Male 11/13/2007 Consumer United States
Primary
Concomitant
Coronary Artery Bypass Other Serious 68 Male 11/15/2007 Consumer Canada
Primary
Concomitant

Drug Data