Atorvastatin combined with Xarelto

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Upper Gastrointestinal Haemorrhage Other Serious 2/10/2009 83 Male 192 lb 8/3/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 4/1/2011 77 Male 176 lb 7/18/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 4/1/2011 77 Male 176 lb 7/28/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 7/1/2011 71 Female 181 lb 8/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 8/7/2011 90 Male 9/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Toxicity To Various Agents Life Threatening 12/31/2009 75 Female 159 lb 9/9/2011 Physician Switzerland
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 12/31/2009 75 Female 159 lb 9/16/2011 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/10/2011 73 Male 12/13/2011 Physician South Africa
Primary
Concomitant
Pulmonary Embolism Disability 1/19/2012 74 Female 2/17/2012 Physician Germany
Primary
Concomitant
Coagulation Time Prolonged Hospitalization 12/1/2011 74 Male 152 lb 3/1/2012 Physician France
Primary
Concomitant
Interacting
Petechiae Hospitalization 2/20/2012 85 Female 117 lb 3/5/2012 Physician Poland
Primary
Secondary
Concomitant
Chest Pain Death 2/5/2012 75 Male 3/5/2012 Physician Poland
Primary
Concomitant
Pulmonary Embolism Disability 1/19/2012 74 Female 3/7/2012 Physician Germany
Primary
Concomitant
Prostatic Disorder Other Serious 2/1/2012 76 Male 215 lb 3/8/2012 Consumer United States
Primary
Concomitant
Prurigo Other Serious 2/24/2012 60 Male 223 lb 3/8/2012 Physician France
Primary
Concomitant
Diarrhoea Death 2/5/2012 75 Male 3/23/2012 Physician Poland
Primary
Concomitant
Overdose Hospitalization 4/3/2012 69 Male 132 lb 4/19/2012 Other Health Professional Singapore
Primary
Concomitant
Dyspnoea Hospitalization 4/3/2012 69 Male 132 lb 4/19/2012 Other Health Professional Singapore
Primary
Concomitant
Dyspnoea Hospitalization 4/3/2012 69 Male 132 lb 4/19/2012 Other Health Professional Singapore
Primary
Concomitant
Prurigo Other Serious 2/23/2012 60 Male 223 lb 4/20/2012 Physician France
Primary
Concomitant
Drug Interaction Hospitalization 12/1/2011 74 Male 152 lb 4/20/2012 Physician France
Primary
Concomitant
Interacting
Hypotension Life Threatening 12/5/2011 64 Female 145 lb 7/31/2012 Other Health Professional Canada
Primary
Concomitant
Arthralgia 1/1/2012 71 Male 210 lb 8/3/2012 Consumer United States
Primary
Concomitant
Cardioversion Hospitalization 76 Female 8/6/2012 Physician Poland
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/9/2012 Physician Canada
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/27/2012 65 Male 8/15/2012 Physician Canada
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/20/2012 67 Female 134 lb 8/16/2012 Physician Germany
Primary
Concomitant
Drug Eruption Hospitalization 2/23/2012 60 Male 8/16/2012 Other Health Professional France
Primary
Concomitant
Drug Eruption Hospitalization 2/23/2012 60 Male 8/20/2012 Other Health Professional France
Primary
Concomitant
Renal Infarct Other Serious 5/20/2012 70 Male 10/30/2012 Physician De
Primary
Concomitant
Cardioversion Hospitalization 76 Female 5/31/2013 Physician Pl
Primary
Concomitant
Melaena Hospitalization 9/5/2012 77 Female 148 lb 9/20/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Implant Site Haematoma Life Threatening 4/8/2012 82 Male 134 lb 11/19/2012 Other Health Professional Ca
Primary
Concomitant
Melaena Hospitalization 9/5/2012 77 Female 148 lb 9/21/2012 Other Health Professional Us
Primary
Concomitant
Interacting
Retinal Artery Occlusion Disability 9/4/2012 67 Male 220 lb 9/28/2012 Other Health Professional Gb
Primary
Concomitant
Torsade De Pointes Hospitalization 7/13/2012 72 Female 119 lb 7/13/2012 Pharmacist Us
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 9/29/2012 83 Female 12/23/2012 Physician Sg
Primary
Concomitant
Ischaemic Stroke Hospitalization 9/27/2012 76 Male 161 lb 12/10/2012 Physician Ru
Primary
Secondary
Nausea Hospitalization 8/2/2012 Female 152 lb 11/2/2012 Pharmacist Us
Primary
Concomitant
Vomiting Hospitalization 3/29/2012 79 Male 154 lb 11/9/2012 Other Health Professional Gb
Primary
Concomitant
Drug Ineffective Other Serious 10/23/2012 65 Female 265 lb 1/21/2013 Physician De
Primary
Secondary
Concomitant
Weight Increased Other Serious 2012 74 Female 134 lb 12/17/2012 Physician Us
Primary
Concomitant
Diarrhoea 7/2/2012 79 Male 11/28/2012 Pharmacist Us
Primary
Concomitant
Procedural Haemorrhage 7/13/2012 79 Male 11/28/2012 Pharmacist Us
Primary
Concomitant
Mouth Haemorrhage 7/4/2012 79 Male 11/28/2012 Pharmacist Us
Primary
Concomitant
Thrombocytopenia Death 10/19/2012 76 Male 12/11/2012 Physician At
Primary
Concomitant
Haemorrhage Other Serious 10/18/2012 74 Female 280 lb 12/10/2012 Physician Gb
Primary
Concomitant
Ischaemic Stroke Disability 10/27/2012 31 Male 196 lb 1/2/2013 Physician Ch
Primary
Concomitant
Hypertension Hospitalization 44 Male 12/20/2012 Physician Ph
Primary
Concomitant
Swelling Other Serious 74 Male 220 lb 12/28/2012 Other Health Professional Gb
Primary
Concomitant
Haematochezia Other Serious 1/4/2013 79 Male 212 lb 1/22/2013 Consumer Us
Primary
Concomitant
Haematuria Other Serious 11/5/2012 69 Male 189 lb 1/28/2013 Other Health Professional Us
Primary
Concomitant
Syncope Hospitalization 1/14/2013 85 Female 240 lb 1/16/2013 Pharmacist Us
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/3/2013 88 Female 112 lb 1/29/2013 Physician Gb
Primary
Concomitant
Tachyarrhythmia Other Serious 11/14/2012 73 Female 152 lb 1/29/2013 Physician De
Primary
Concomitant
Ischaemic Stroke Hospitalization 12/2012 Female 1/22/2013 Physician Cl
Primary
Concomitant
Nausea 12/2012 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Gastrointestinal Haemorrhage Death 76 Male 3/27/2013 Other Health Professional Us
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 6/2012 78 Male 2/11/2013 Other Health Professional Us
Primary
Secondary
Interacting
Rhabdomyolysis Hospitalization 2/8/2013 71 Female 203 lb 4/16/2013 Pharmacist Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/2013 87 Female 4/10/2013 Consumer Us
Primary
Concomitant
Oedema Other Serious Female 3/12/2013 Physician Ca
Primary
Secondary
Concomitant
Potentiating Drug Interaction Death 3/4/2013 79 Male 3/28/2013 Physician Ch
Primary
Concomitant
Interacting
Transient Ischaemic Attack Other Serious 1/2013 73 Female 130 lb 3/15/2013 Other Health Professional Us
Primary
Concomitant
Syncope Hospitalization 1/14/2013 86 Female 240 lb 4/9/2013 Pharmacist Us
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 12/1/2012 57 Female 123 lb 4/1/2013 Pharmacist Gb
Primary
Concomitant
Ulcer Haemorrhage Hospitalization 1/14/2013 85 Female 240 lb 4/10/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Interacting
Melaena Life Threatening 4/1/2013 77 Male 167 lb 4/8/2013 Pharmacist Us
Primary
Concomitant
Weight Decreased Other Serious 3/29/2013 66 Female 8/19/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Nervous System Disorder Life Threatening 3/3/2013 77 Male 10/30/2013 Physician Gb
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/11/2013 90 Female 4/25/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Shock Hospitalization 4/22/2013 55 Female 139 lb 5/15/2013 Physician Fr
Primary
Concomitant
Haemoglobin Decreased Hospitalization 4/11/2013 90 Female 7/23/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 4/11/2013 90 Female 4/29/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 4/11/2013 90 Female 5/3/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 4/2013 90 Female 120 lb 5/30/2013 Other Health Professional Us
Primary
Concomitant
Glomerular Filtration Rate Decreased Hospitalization 1/2013 69 Male 254 lb 5/10/2013 Consumer Us
Primary
Secondary
Concomitant
Ischaemic Stroke Death 4/4/2013 89 Female 5/14/2013 Other Health Professional Fr
Primary
Concomitant
Oedema Mouth Other Serious 4/2013 50 Female 5/15/2013 Pharmacist Gb
Primary
Concomitant
Pulmonary Embolism Hospitalization 60 Male 135 lb 10/4/2013 Physician Ca
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 5/1/2013 56 Male 6/12/2013 Physician Us
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 5/1/2013 56 Male 5/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 4/4/2013 80 Male 6/4/2013 Other Health Professional Gb
Primary
Concomitant
Renal Impairment Hospitalization 5/10/2013 83 Male 8/28/2013 Physician Fr
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 4/13/2013 83 Male 176 lb 7/26/2013 Physician Es
Primary
Concomitant
Splenic Rupture Life Threatening 4/21/2013 63 Male 6/14/2013 Physician Gb
Primary
Concomitant
Paraesthesia Other Serious 2/9/2013 71 Female 6/27/2013 Physician Se
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Hospitalization 4/2/2013 80 NotSpecified 6/28/2013 Physician De
Primary
Concomitant
Gastrointestinal Disorder Other Serious 5/16/2013 67 Male 242 lb 7/1/2013 Physician Gb
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 4/2/2013 NotSpecified 7/1/2013 Other Health Professional De
Primary
Concomitant
Hepatocellular Injury Hospitalization 5/20/2013 72 Male 192 lb 7/15/2013 Pharmacist De
Primary
Concomitant
Sepsis Hospitalization 6/7/2013 77 Female 139 lb 8/14/2013 Physician De
Primary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 4/2/2013 80 NotSpecified 7/5/2013 Physician De
Primary
Concomitant
Thrombocytopenia Other Serious 71 Female 7/12/2013 Physician Br
Primary
Concomitant
Hepatitis Acute Hospitalization 11/2/2012 81 Male 7/10/2013 Physician Es
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/28/2013 81 Female 128 lb 7/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 2013 Female 130 lb 8/29/2013 Consumer Us
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 5/27/2013 76 Female 150 lb 7/15/2013 Other Health Professional Jp
Primary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 7/3/2013 77 Female 167 lb 8/20/2013 Pharmacist Us
Primary
Concomitant
Rectal Haemorrhage Hospitalization 6/24/2013 63 Male 227 lb 7/18/2013 Physician Gb
Primary
Concomitant
Pain In Extremity Other Serious 3/2013 71 Female 130 lb 7/24/2013 Consumer Us
Primary
Secondary
Concomitant
Occult Blood Positive Hospitalization 5/27/2013 76 Female 150 lb 7/24/2013 Pharmacist Jp
Primary
Concomitant
Interacting
Off Label Use Other Serious 7/31/2013 69 Male 11/4/2013 Physician Ie
Primary
Concomitant
Cerebrovascular Accident Hospitalization 7/20/2013 87 Female 115 lb 8/22/2013 Physician Ch
Primary
Concomitant
Skin Discolouration Other Serious 6/19/2013 75 Male 9/19/2013 Pharmacist Ie
Primary
Concomitant
Ischaemic Stroke Disability 5/10/2013 58 Female 244 lb 9/27/2013 Pharmacist Us
Primary
Concomitant
Spontaneous Haemorrhage Life Threatening 8/2/2013 71 Female 145 lb 8/6/2013 Pharmacist Us
Primary
Concomitant
Uterine Haemorrhage Other Serious 4/20/2013 72 Female 172 lb 8/12/2013 Physician De
Primary
Concomitant
Headache Other Serious 52 Male 268 lb 8/15/2013 Other Health Professional Gb
Primary
Concomitant
Subdural Haemorrhage Hospitalization 80 Male 134 lb 8/16/2013 Physician Gb
Primary
Concomitant
Nausea Disability 6/11/2013 63 Male 168 lb 8/28/2013 Physician Gb
Primary
Concomitant
Vomiting Hospitalization 7/30/2013 66 Male 9/4/2013 Physician Fi
Primary
Concomitant
Cerebellar Infarction Hospitalization 8/19/2013 82 Male 115 lb 9/30/2013 Physician Jp
Primary
Concomitant
Vomiting Other Serious 6/2013 77 Male 9/5/2013 Other Health Professional De
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/2013 63 Male 186 lb 9/6/2013 Consumer Us
Primary
Secondary
Concomitant
Haematuria Hospitalization 7/12/2013 69 Male 9/6/2013 Physician Ch
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/3/2013 66 Male 201 lb 9/5/2013 Pharmacist Us
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 8/25/2013 84 Male 154 lb 10/9/2013 Physician Br
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/4/2013 76 Male 154 lb 11/28/2013 Physician At
Primary
Concomitant
Excoriation 8/2013 83 Male 9/10/2013 Consumer Us
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/2013 63 Male 186 lb 9/16/2013 Consumer Us
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/2012 82 Male 11/29/2013 Physician De
Primary
Concomitant
Visual Impairment Disability 8/16/2013 79 Male 165 lb 9/23/2013 Pharmacist Gb
Primary
Concomitant
Iron Deficiency Anaemia Other Serious 6/5/2013 81 Female 157 lb 10/16/2013 Physician Gb
Primary
Concomitant
Spontaneous Haematoma Hospitalization 2013 82 Female 12/24/2013 Physician Br
Primary
Concomitant
Oedema Peripheral Other Serious 8/8/2013 64 Female 179 lb 9/27/2013 Physician De
Primary
Concomitant
Rash Generalised Other Serious 6/15/2013 76 Male 9/30/2013 Other Health Professional Se
Primary
Concomitant
Haemorrhage Intracranial Life Threatening 9/14/2013 0 Male 211 lb 9/26/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 8/12/2013 79 Male 10/1/2013 Pharmacist Ch
Primary
Concomitant
Respiratory Distress Death 9/24/2013 67 Male 223 lb 9/30/2013 Pharmacist Us
Primary
Concomitant
Thrombocytopenia Other Serious 9/2013 88 NotSpecified 10/15/2013 Pharmacist Ca
Primary
Concomitant
Splenic Haemorrhage Death Female 184 lb 11/14/2013 Physician Us
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/6/2013 Female 12/31/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Urticaria Other Serious Female 10/11/2013 Consumer Gb
Primary
Secondary
Concomitant
Urticaria Other Serious Female 10/14/2013 Consumer Gb
Primary
Secondary
Concomitant
Visual Field Defect Disability 9/21/2013 68 Male 10/17/2013 Other Health Professional Fi
Primary
Concomitant
Nausea Life Threatening 10/5/2013 66 Female 104 lb 10/22/2013 Physician Gb
Primary
Concomitant
Wheezing Other Serious 2/2/2012 79 Female 10/24/2013 Consumer Ca
Primary
Concomitant
Cerebral Haemorrhage Death 10/13/2013 81 Female 115 lb 10/31/2013 Other Health Professional Us
Primary
Concomitant
Platelet Count Decreased Other Serious 10/15/2013 78 Male 205 lb 12/2/2013 Physician De
Primary
Concomitant
Intracranial Pressure Increased Death 8/27/2013 61 Male 210 lb 10/26/2013 Consumer Us
Primary
Concomitant
Respiratory Distress Hospitalization 9/2013 76 Male 10/31/2013 Physician Fr
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 9/25/2013 76 Male 11/1/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Weight Loss Poor Other Serious 2/2013 82 Female 200 lb 12/5/2013 Consumer Us
Primary
Secondary
Concomitant
Aortic Aneurysm Rupture Hospitalization 10/21/2013 70 Male 240 lb 11/6/2013 Physician At
Primary
Concomitant
Renal Failure Hospitalization 10/25/2013 82 Male 11/21/2013 Physician Gb
Primary
Concomitant
Syncope Life Threatening 80 Male 12/20/2013 Other Health Professional Ca
Primary
Concomitant
Ischaemic Stroke Hospitalization 8/16/2013 87 Female 163 lb 12/9/2013 Physician Nl
Primary
Concomitant
Pericarditis Life Threatening 5/22/2013 74 Male 209 lb 12/17/2013 Pharmacist Us
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 7/3/2013 77 Female 167 lb 11/26/2013 Other Health Professional Us
Primary
Secondary
Concomitant

Drug Data