Atorvastatin Calcium combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Burning Sensation Other Serious 10/17/2005 57 Male 218 lb 1/23/2006 Other Health Professional Germany
Primary
Concomitant
Urine Colour Abnormal 12/1/2005 Male 2/7/2006 Physician United Kingdom
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2003 53 Female 2/7/2006 Consumer Canada
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 4/9/2004 83 Female 163 lb 2/9/2006 Physician Germany
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 37 Male 3/6/2006 Consumer France
Primary
Secondary
Loss Of Consciousness Disability 3/17/2005 54 Male 2/24/2006 Other Health Professional Australia
Primary
Concomitant
Hypotension Hospitalization 2/2/2006 70 Male 3/3/2006 United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 2/26/2006 72 Male 224 lb 3/28/2006 Consumer United Kingdom
Primary
Concomitant
Dizziness Other Serious 9/13/2005 64 Male 209 lb 4/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Cold Sweat Other Serious 3/21/2006 57 Male 324 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2005 Female 12/12/2005 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 70 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 5/12/2006 75 Male 170 lb 5/12/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 4/24/2006 70 Male 7/14/2006 United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/10/2005 45 Female 1/27/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Local Swelling Hospitalization 6/27/2006 Male 8/14/2006 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/23/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/6/2004 Male 214 lb 9/7/2006 Australia
Primary
Concomitant
Haemolytic Anaemia Hospitalization 3/20/2006 71 Female 9/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 4/24/2006 70 Male 9/20/2006 United States
Primary
Secondary
Concomitant
Local Swelling Hospitalization 6/27/2006 Male 10/5/2006 Physician Netherlands
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/7/2006 77 Male 236 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 55 Male 159 lb 10/6/2006 Canada
Primary
Concomitant
Psychomotor Retardation Hospitalization 5/24/2005 67 Male 10/25/2006 Consumer Australia
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 63 Female 1/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Iiird Nerve Paresis Disability 11/19/2006 63 Female 157 lb 2/6/2007 Consumer United Kingdom
Primary
Concomitant
Neck Pain Hospitalization 8/29/2003 68 Male 2/8/2007 France
Primary
Concomitant
Somnolence Hospitalization 75 Female 3/20/2007 Norway
Primary
Concomitant
Pancreatitis Chronic Other Serious 63 Female 4/13/2007 Other Health Professional Belgium
Primary
Concomitant
Pyrexia Hospitalization 4/5/2006 Female 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema Life Threatening 6/12/2007 79 Female 7/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
Presyncope Other Serious 6/5/2007 Male 170 lb 7/23/2007 Physician France
Primary
Secondary
Concomitant
Feeling Abnormal Hospitalization 6/16/2007 Male 139 lb 8/9/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 3/4/2006 66 Female 165 lb 8/14/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/1/2007 Female 10/5/2007 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious Female 189 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Pallor Life Threatening 9/19/2007 69 Male 11/6/2007 United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 5/9/2007 58 Female 308 lb 11/20/2007 Consumer United Kingdom
Primary
Concomitant
Eczema Asteatotic Hospitalization 5/23/2007 Female 11/20/2007 United Kingdom
Primary
Concomitant
Renal Failure Life Threatening 7/18/2007 71 Male 11/26/2007 Other Health Professional France
Primary
Secondary
Coronary Artery Occlusion Other Serious 9/24/2007 76 Male 11/19/2007 Australia
Primary
Concomitant
Vertigo Other Serious 8/2/2007 Female 131 lb 11/28/2007 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 10/1/2007 57 Female 271 lb 11/30/2007 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 4/1/2007 Female 12/20/2007 Other Health Professional United States
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/14/2008 68 Male 157 lb 3/6/2008
Primary
Concomitant
Vomiting Life Threatening 1/14/2008 68 Male 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 3/26/2008 63 Female 184 lb 5/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pitting Oedema Other Serious 4/17/2008 71 Male 5/14/2008 Other Health Professional Denmark
Primary
Concomitant
Arthralgia Hospitalization 6/7/2008 78 Male 6/17/2008 Physician Greece
Primary
Concomitant
Polymyalgia Rheumatica Hospitalization 6/7/2008 78 Male 6/27/2008 Physician Greece
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 11/13/2007 60 Male 231 lb 7/30/2008 Physician Switzerland
Primary
Concomitant
Rash Generalised 11/28/2007 Male 208 lb 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 8/1/2008 66 Female 9/19/2008 Physician France
Primary
Concomitant
Liver Disorder Other Serious 5/28/2008 80 Female 10/1/2008 Other Health Professional Spain
Primary
Concomitant
Vertigo Hospitalization 1/1/2003 Female 216 lb 10/14/2008 Other Health Professional Denmark
Primary
Concomitant
Vertigo Hospitalization 1/1/2003 Female 216 lb 10/14/2008 Other Health Professional Denmark
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 10/14/2008 Physician Spain
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 9/1/2008 68 Female 10/17/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 46 Female 390 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 46 Female 390 lb 10/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 5/17/2008 Female 120 lb 10/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pemphigus Disability 3/1/2008 64 Female 10/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 4/16/2006 Male 10/22/2008 Denmark
Primary
Concomitant
Pemphigus Disability 3/1/2008 64 Female 10/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
Skin Necrosis Other Serious 8/16/2008 66 Female 154 lb 11/6/2008 Physician France
Primary
Concomitant
Blood Glucose Increased Other Serious 9/1/2008 57 Male 214 lb 11/17/2008 Pharmacist Australia
Primary
Concomitant
Vasculitis Hospitalization 10/1/2008 55 Female 11/24/2008 Physician France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 12/19/2008 Physician France
Primary
Concomitant
Renal Failure Acute Life Threatening 12/10/2008 56 Male 1/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Lacunar Infarction Hospitalization 9/25/2008 2/12/2009 Physician Spain
Primary
Concomitant
Renal Failure Hospitalization 12/1/2008 65 Male 2/18/2009 Physician France
Primary
Concomitant
Renal Failure Hospitalization 11/1/2008 65 Male 2/27/2009 Physician France
Primary
Concomitant
Skin Necrosis Other Serious 8/16/2008 66 Female 154 lb 3/5/2009 Physician France
Primary
Concomitant
Hypoglycaemia Other Serious 7/25/2008 73 Male 3/16/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Haemorrhagic Transformation Stroke Hospitalization 9/7/2006 58 Female 3/18/2009 Korea, Republic Of
Primary
Concomitant
Brain Stem Infarction Hospitalization 9/10/2006 46 Female 3/17/2009 Korea, Republic Of
Primary
Concomitant
Unintended Pregnancy Other Serious 2/1/2009 Female 216 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Unintended Pregnancy Other Serious 2/1/2009 Female 216 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 8/26/2008 61 Female 4/13/2009 Physician Spain
Primary
Secondary
Concomitant
Unintended Pregnancy Other Serious Female 216 lb 4/30/2009 Other Health Professional United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 10/1/2008 55 Female 5/12/2009 Physician France
Primary
Concomitant
Rash Papular 10/16/2008 55 Female 234 lb 5/21/2009 Other Health Professional France
Primary
Concomitant
Myopathy Other Serious 10/3/2008 66 Male 161 lb 5/22/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 10/16/2008 55 Female 234 lb 5/27/2009 Physician France
Primary
Concomitant
Arthralgia Disability 2/1/2009 61 Male 249 lb 6/3/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myopathy Other Serious 10/3/2008 66 Male 161 lb 6/9/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Headache Hospitalization 2/25/2009 58 Male 6/15/2009 Physician Italy
Primary
Concomitant
Urticaria Life Threatening 6/11/2009 Female 225 lb 6/25/2009 Physician United Kingdom
Primary
Concomitant
Vertigo Life Threatening 6/2/2009 84 Male 165 lb 7/21/2009 Other Health Professional Austria
Primary
Concomitant
Skin Burning Sensation 8/1/2008 Female 275 lb 8/21/2009 Physician United States
Primary
Concomitant
Dizziness Male 8/21/2009 United States
Primary
Concomitant
Myalgia Hospitalization 3/1/2009 64 9/14/2009 Physician Switzerland
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 9/1/2009 9/21/2009 Physician Greece
Primary
Concomitant
Skin Ulcer Life Threatening 72 Male 9/30/2009 United Kingdom
Primary
Concomitant
Cardiogenic Shock Life Threatening 9/18/2009 52 Male 152 lb 10/12/2009 Physician Canada
Primary
Concomitant
Penile Oedema Other Serious 6/1/2009 56 Male 10/16/2009 Pharmacist Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 10/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 8/16/2008 66 Female 154 lb 11/3/2009 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 11/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/29/2009 72 Female 11/12/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 11/20/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 75 Male 12/15/2009 Physician Belgium
Primary
Concomitant
Hyperhidrosis Other Serious 6/1/2008 55 Male 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnambulism Death 11/1/2009 48 Male 12/14/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2009 73 Female 2/3/2010 Physician Spain
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Death 9/1/2008 73 Female 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2009 Male 273 lb 2/22/2010 Physician United Kingdom
Primary
Concomitant
Circulatory Collapse Other Serious 9/16/2009 Male 150 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 63 Male 151 lb 3/2/2010
Primary
Concomitant
Myocardial Infarction Hospitalization 3/2/2010 59 Female 3/9/2010 Consumer Colombia
Primary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment 1/18/2010 72 Female 265 lb 3/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Cord Disorder Hospitalization 60 Male 176 lb 3/26/2010 Consumer Brazil
Primary
Secondary
Concomitant
Therapy Cessation Hospitalization 3/1/2010 Female 3/26/2010 Pharmacist Australia
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 1/4/2010 Male 231 lb 3/26/2010 Consumer United Kingdom
Primary
Concomitant
Embolic Stroke Hospitalization 79 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Life Threatening 1/12/2010 78 Male 4/2/2010 Other Health Professional Spain
Primary
Secondary
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 4/27/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/25/2009 66 Male 201 lb 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Fall Other Serious 12/1/2008 75 Female 150 lb 5/11/2010 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 5/21/2010 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 4/1/2009 73 Female 5/27/2010 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 6/17/2010 Physician Japan
Primary
Secondary
Concomitant
Pulse Absent Other Serious 4/19/2010 69 Female 6/10/2010 United States
Primary
Secondary
Lacunar Infarction Hospitalization 10/15/2008 64 Male 192 lb 7/5/2010 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 4/28/2010 85 Female 126 lb 7/26/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Hospitalization 7/8/2010 79 Male 8/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2009 75 Female 143 lb 9/14/2010 Other Health Professional France
Primary
Secondary
Renal Disorder Other Serious 10/16/2009 55 Male 179 lb 9/29/2010 Physician Poland
Primary
Concomitant
Metastases To Liver Hospitalization 11/8/2010 70 Male 291 lb 12/2/2010 Physician United Kingdom
Primary
Concomitant
Large Intestine Carcinoma Hospitalization 10/1/2010 76 Male 148 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection 1/1/2010 12/22/2010 Physician United States
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2010 Male 148 lb 1/26/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data