Atorvastatin Calcium combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Other Serious 9/5/2005 Male 185 lb 1/27/2006 United States
Primary
Concomitant
Hyponatraemia Other Serious 12/21/2005 70 Male 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 7/7/2005 82 Male 1/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nitritoid Crisis Other Serious 8/22/2002 63 Male 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/8/2006 Other Health Professional
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Nightmare Disability 8/1/2005 69 Male 2/20/2006 Pharmacist United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthma Other Serious 1/15/2006 54 Female 179 lb 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 11/17/2003 61 Male 159 lb 2/23/2006 Physician Poland
Primary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2003 Male 3/3/2006 Consumer Australia
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Hospitalization 2/2/2006 73 Female 2/13/2006 Consumer France
Primary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 3/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Contusion Hospitalization 3/17/2004 53 Female 190 lb 12/27/2005 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Swelling Face Other Serious 3/20/2005 72 Male 278 lb 12/21/2005 Consumer United States
Primary
Concomitant
Troponin T Increased Hospitalization 3/2/2005 77 Male 134 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoptysis Other Serious 2/26/2006 72 Male 224 lb 3/28/2006 Consumer United Kingdom
Primary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 3/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 1/1/2002 47 Male 3/31/2006 Physician Poland
Primary
Concomitant
Skin Exfoliation Other Serious 3/2/2006 61 Male 4/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 68 Male 154 lb 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Hospitalization 2/1/2003 55 Male 4/27/2006 Physician Norway
Primary
Secondary
Concomitant
Retinal Artery Embolism Hospitalization 4/27/2004 74 Female 4/28/2006 Norway
Primary
Concomitant
Pharyngeal Oedema Hospitalization 12/29/2005 66 Male 4/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Facial Palsy Disability 3/11/2005 64 Male 4/26/2006 Ireland
Primary
Concomitant
Urinary Tract Infection Death 1/25/2006 72 Female 150 lb 5/1/2006 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Vomiting Other Serious 1/7/2004 50 Female 5/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Anosmia Other Serious 1/29/2006 50 Male 35 lb 5/17/2006 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2004 72 Male 187 lb 5/11/2006 Physician India
Primary
Concomitant
Myocardial Infarction Hospitalization 8/1/2005 70 Female 122 lb 1/13/2006 Physician United States
Primary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 5/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Other Serious 4/17/2006 71 Female 141 lb 6/1/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 6/9/2006 Physician United Kingdom
Primary
Concomitant
Haematochezia Hospitalization 4/9/2005 Male 134 lb 6/28/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 9/5/2005 Male 185 lb 6/30/2006 United States
Primary
Concomitant
Epilepsy Hospitalization 5/19/2006 58 Female 6/28/2006 Physician Austria
Primary
Concomitant
Tongue Biting Hospitalization 5/19/2006 58 Female 6/28/2006 Physician Austria
Primary
Concomitant
Haematochezia Hospitalization 4/7/2005 Male 134 lb 7/17/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Hypertension Hospitalization 4/6/2006 66 Male 7/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Biting Hospitalization 5/19/2006 58 Female 7/27/2006 Physician Australia
Primary
Concomitant
Drug Hypersensitivity Hospitalization 4/6/2006 66 Male 7/28/2006 Other Health Professional United Kingdom
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Subdural Haemorrhage Death 7/23/2004 Female 143 lb 8/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious Female 8/3/2006 Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Female 8/9/2006 Canada
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 6/12/2006 55 Female 8/9/2006 United States
Primary
Concomitant
Angina Pectoris Other Serious 71 Male 8/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypersensitivity Hospitalization 3/31/2006 66 Male 8/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/16/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 7/4/2006 73 Female 8/23/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 5/29/2006 86 Female 8/25/2006 United Kingdom
Primary
Secondary
Concomitant
Palpitations Other Serious 1/13/2006 61 Male 258 lb 8/25/2006 Physician United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 71 Male 8/25/2006 United Kingdom
Primary
Concomitant
Condition Aggravated Other Serious 71 Male 9/1/2006 United Kingdom
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/11/2006 Other Health Professional Netherlands
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 9/11/2006 Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 9/22/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/29/2006 Other Health Professional Netherlands
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 8/10/2006 77 Male 10/18/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 Male 10/11/2006 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 70 Male 10/20/2006 Brazil
Primary
Secondary
Concomitant
Pollakiuria Other Serious 7/1/2006 65 Female 88 lb 10/17/2006 Physician United Kingdom
Primary
Concomitant
Palpitations Other Serious 12/13/2005 60 Male 258 lb 10/24/2006 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 8/11/2006 64 Male 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tibia Fracture Hospitalization 1/20/2006 56 Male 194 lb 11/9/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 11/2/2006 48 Female 11/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dizziness Disability 3/1/2005 79 Female 11/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Other Serious 3/15/1999 72 Male 169 lb 11/17/2006 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/1/2005 Male 11/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sciatica Hospitalization 3/28/2006 75 Male 120 lb 11/27/2006 United States
Primary
Concomitant
Memory Impairment Disability 1/1/2006 53 Female 12/11/2006 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 11/5/2006 80 Female 132 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/1998 Female 12/12/2006 Consumer Canada
Primary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/9/2002 65 Male 254 lb 3/3/2005 United States
Primary
Concomitant
Chest Pain Other Serious 12/22/2006 1/30/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 63 Female 3/5/2007 United Kingdom
Primary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 63 Female 3/9/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 63 Female 3/20/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 1/1/2007 63 Female 3/13/2007 United Kingdom
Primary
Secondary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 63 Female 3/15/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/1/2006 46 Male 344 lb 3/27/2007 Physician United Kingdom
Primary
Concomitant
Mouth Ulceration Disability 2/1/2007 4/4/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/15/2007 84 Female 3/30/2007 Physician United States
Primary
Concomitant
Myositis Disability 12/1/2006 81 Female 4/6/2007 Consumer United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 4/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Disability 2/12/2002 Male 4/20/2007 United Kingdom
Primary
Concomitant
Skin Hypertrophy Other Serious 60 Male 5/10/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 3/1/2006 Female 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 1/1/2007 77 154 lb 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 1/24/2007 69 Female 5/18/2007 Consumer United Kingdom
Primary
Concomitant
Convulsion Hospitalization 5/22/2007 78 Male 6/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 6/14/2007 73 Female 168 lb 8/15/2007 Physician United Kingdom
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 8/16/2007 Physician Philippines
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/14/2007 73 Female 168 lb 8/22/2007 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/23/2007 Physician Spain
Primary
Secondary
Concomitant
Death Hospitalization 7/30/2007 Male 8/24/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2005 42 Male 8/30/2007 Physician Spain
Primary
Secondary
Concomitant
Feeling Drunk Other Serious 8/2/2007 61 Male 206 lb 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious Female 189 lb 10/12/2007 Physician United Kingdom
Primary
Concomitant
Blood Glucose Fluctuation Other Serious 8/28/2007 60 Male 220 lb 10/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 72 Male 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 72 Male 11/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 10/20/2007 Male 11/20/2007 United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Life Threatening 10/20/2007 Male 11/20/2007 United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 7/15/2007 83 Male 11/21/2007 Physician United Kingdom
Primary
Concomitant
Troponin Increased Life Threatening 10/20/2007 67 Male 154 lb 11/26/2007 United Kingdom
Primary
Secondary
Concomitant
Nausea Other Serious 2/27/2007 62 Male 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 10/20/2007 67 Male 154 lb 11/26/2007 United Kingdom
Primary
Secondary
Concomitant
Syncope Vasovagal Disability 5/10/2001 63 Male 12/14/2007 United Kingdom
Primary
Secondary
Concomitant
Nitritoid Reaction Other Serious 8/22/2002 63 Male 12/13/2007 United Kingdom
Primary
Secondary
Concomitant
Hip Fracture Hospitalization 1/1/2007 Male 12/26/2007 Consumer Australia
Primary
Concomitant
Rhabdomyolysis Other Serious 42 Male 12/20/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Skin Ulcer Death 10/19/2007 71 Male 154 lb 12/27/2007 Physician Greece
Primary
Concomitant
Syncope Vasovagal Disability 5/10/2001 63 Male 12/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 2/8/2008 Sweden
Primary
Concomitant
Tremor Hospitalization 1/1/2007 81 Male 2/12/2008 Other Health Professional France
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 50 Male 2/15/2008 Physician Philippines
Primary
Secondary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/15/2003 Male 267 lb 2/21/2008 Australia
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 1/14/2008 72 Female 143 lb 2/22/2008 Consumer Turkey
Primary
Concomitant
Tinnitus Hospitalization 7/1/2007 Female 2/15/2008 United Kingdom
Primary
Concomitant
Troponin Increased Hospitalization 2/20/2008 62 Female 3/6/2008 Sweden
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/11/2008 Other Health Professional Netherlands
Primary
Concomitant
Sinus Congestion 1/17/2008 Female 3/15/2008 United States
Primary
Concomitant
Troponin Increased Hospitalization 2/20/2008 62 Female 3/19/2008 Sweden
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 3/28/2008 Sweden
Primary
Concomitant
Muscular Weakness Disability 87 Male 180 lb 3/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/27/2008 Other Health Professional Netherlands
Primary
Concomitant
Dyspepsia Other Serious 1/1/2006 77 Female 154 lb 4/8/2008 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/9/2007 Male 4/28/2008 Physician United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 82 Female 5/2/2008 United Kingdom
Primary
Secondary
Concomitant

Drug Data