Aspirin combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 10/24/2005 Male 10/25/2005 United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 7/12/2005 78 Female 1/30/2006 Consumer Italy
Primary
Concomitant
Heart Rate Increased Life Threatening 8/20/2005 86 Female 2/8/2006 Japan
Primary
Concomitant
Bradycardia Other Serious 1/4/2006 52 Male 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 11/20/2005 75 Male 3/2/2006 Consumer Japan
Primary
Concomitant
Tremor Hospitalization 1/31/2006 73 Female 3/21/2006 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Pneumonia Life Threatening 11/20/2005 75 Male 4/24/2006 Consumer Japan
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 57 Female 12/1/2005 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/6/2006 84 Female 80 lb 7/17/2006 Physician Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 4/16/2006 60 Male 300 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 6/6/2006 84 Female 80 lb 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 6/14/2006 89 Unknown 8/4/2006 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/22/2005 Male 8/17/2006 Consumer France
Primary
Concomitant
Interacting
Granulocytopenia Required Intervention 11/23/2005 55 Male 2/27/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/26/2006 85 Female 8/24/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Other Serious 7/2/2006 89 9/7/2006 Denmark
Primary
Concomitant
Gynaecomastia Hospitalization 8/22/2006 Male 10/3/2006 United Kingdom
Primary
Secondary
Concomitant
Psychomotor Retardation Hospitalization 5/24/2005 67 Male 10/25/2006 Consumer Australia
Primary
Secondary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 68 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Weight Decreased Other Serious 54 Female 12/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Convulsion Other Serious 72 Female 12/7/2006 Physician United Kingdom
Primary
Concomitant
Convulsion Other Serious 11/4/2006 72 Female 12/12/2006 Physician United Kingdom
Primary
Concomitant
Feeling Abnormal Disability 10/10/2006 72 Male 12/29/2006 Other Health Professional France
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 11/1/2006 43 Female 179 lb 4/9/2007 Physician United Kingdom
Primary
Concomitant
Supraventricular Extrasystoles Other Serious 1/1/2007 56 Male 4/13/2007 Physician Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 5/28/2006 Male 5/7/2007 Physician Australia
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/19/2005 73 Male 135 lb 5/2/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/26/2006 85 Female 5/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chorea Other Serious 5/19/2005 73 Male 135 lb 5/8/2007 Physician United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/19/2005 73 Male 135 lb 5/4/2007 United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/19/2005 73 Male 135 lb 5/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Chorea Other Serious 5/19/2005 73 Male 135 lb 5/12/2007 United Kingdom
Primary
Concomitant
Transplant 3/23/2007 65 Male 5/29/2007 United States
Primary
Concomitant
Gait Disturbance Hospitalization 9/19/2006 52 Female 6/6/2007 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Otorhinolaryngological Surgery Hospitalization 5/24/2007 48 Male 7/6/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Brain Stem Haemorrhage Other Serious 5/27/2007 Male 223 lb 8/7/2007 Australia
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/21/2007 66 Male 10/9/2007 Physician Japan
Primary
Concomitant
Drug Toxicity Other Serious 76 Female 10/19/2007 United Kingdom
Primary
Concomitant
Erythema Multiforme Disability 6/27/2007 78 Female 104 lb 11/26/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Erythema Multiforme Disability 6/27/2007 78 Female 104 lb 11/23/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Somnolence Hospitalization 10/8/2007 Male 1/2/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Interacting
Somnolence Hospitalization 10/8/2007 Male 1/4/2008 Pharmacist United Kingdom
Primary
Concomitant
Interacting
Sleep Disorder Hospitalization 59 Male 1/16/2008 Physician Switzerland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/14/2007 56 Female 154 lb 1/28/2008 Physician Austria
Primary
Concomitant
Epistaxis Hospitalization 11/1/2006 62 Female 11/29/2007 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/27/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 76 Female 2/29/2008 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/1/2006 Male 3/7/2008 Physician Australia
Primary
Secondary
Concomitant
Sinusitis Hospitalization 6/6/2006 Male 3/10/2008 Physician United States
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 2/28/2008 Denmark
Primary
Secondary
Concomitant
Chorea Other Serious 5/19/2005 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Chorea Other Serious 5/19/2005 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/19/2005 73 Male 135 lb 3/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 3/31/2008 Denmark
Primary
Secondary
Concomitant
Duodenal Ulcer Perforation Hospitalization 8/2/2005 69 Female 4/9/2008 Physician Denmark
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 4/1/2008 57 Male 223 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/17/2006 78 Male 199 lb 6/12/2008 Physician United States
Primary
Secondary
Concomitant
Vaginal Discharge 2/1/2008 Female 117 lb 6/12/2008 Consumer United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 76 Male 6/13/2008 France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious Male 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Hospitalization 8/2/2005 69 Female 6/17/2008 Denmark
Primary
Secondary
Concomitant
Metabolic Encephalopathy Hospitalization 76 Male 7/2/2008 France
Primary
Concomitant
Death Death Male 7/9/2008 Physician Germany
Primary
Concomitant
Loss Of Consciousness Other Serious Female 170 lb 7/25/2008 Physician United Kingdom
Primary
Concomitant
Loss Of Consciousness Other Serious Female 170 lb 8/15/2008 Physician United Kingdom
Primary
Concomitant
Neutropenia Other Serious 6/1/2008 Female 8/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Rhabdomyolysis Death 2/13/2008 Male 9/10/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/20/2008 Male 183 lb 9/16/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 6/23/2008 Male 9/16/2008 Physician France
Primary
Concomitant
Urinary Incontinence Hospitalization 6/8/2007 Female 9/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence Other Serious 7/2/2006 89 10/22/2008 Denmark
Primary
Concomitant
Suicide Attempt Hospitalization 10/27/2008 Female 198 lb 10/29/2008 Physician Germany
Primary
Secondary
Confusional State Other Serious 10/24/2008 75 Female 11/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Confusional State Other Serious 10/24/2008 75 Female 11/17/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 10/27/2008 Female 198 lb 11/18/2008 Physician Germany
Primary
Secondary
Head Injury Hospitalization 4 Male 29 lb 11/26/2008 Italy
Primary
Secondary
Overdose Hospitalization 9/5/2008 51 Male 11/24/2008 Other Health Professional Denmark
Primary
Concomitant
Weight Increased Other Serious Male 12/29/2008 Other Health Professional Ireland
Primary
Concomitant
Myocardial Infarction Life Threatening 1/18/2009 65 Male 223 lb 2/9/2009 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2000 59 Male 2/6/2009 Physician New Zealand
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2000 59 Male 2/10/2009 Physician New Zealand
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/6/2009 Other Health Professional France
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/2/2009 United Kingdom
Primary
Concomitant
Urine Output Decreased Hospitalization 1/15/2009 65 Male 3/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Insomnia Other Serious 7/1/2008 67 Male 132 lb 3/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Liver Injury Hospitalization 63 Female 3/11/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2008 44 Male 3/17/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vomiting Other Serious Male 256 lb 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 25 Male 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Speech Disorder Other Serious 8/26/2008 Male 4/6/2009 Other Health Professional
Primary
Concomitant
Weight Increased Other Serious 11/27/2008 Male 4/8/2009 Other Health Professional Ireland
Primary
Concomitant
Spinal Compression Fracture Hospitalization 2/3/2009 Male 198 lb 4/8/2009 Physician Australia
Primary
Concomitant
Urinary Incontinence Life Threatening 12/1/2008 90 Female 4/22/2009 Other Health Professional France
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/2/2008 43 Male 218 lb 5/22/2009 Pharmacist United States
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 25 Male 6/3/2009 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 3/4/2009 Female 6/19/2009 Physician Germany
Primary
Concomitant
Overdose Hospitalization 1/15/2009 Male 7/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/4/2009 Female 7/27/2009 Physician Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 6/8/2009 52 Female 7/24/2009 Physician United Kingdom
Primary
Concomitant
Skin Burning Sensation 9/28/2008 Male 8/21/2009 United States
Primary
Concomitant
Postictal State Other Serious 7/13/2006 42 Female 9/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Memory Impairment Hospitalization 10/8/2007 Male 9/25/2009 United Kingdom
Primary
Concomitant
Tachycardia Hospitalization Female 10/7/2009 Consumer United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 9/11/2008 62 Male 174 lb 10/6/2009 Consumer United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization Female 10/22/2009 Consumer United Kingdom
Primary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Overdose Hospitalization 1/15/2009 61 Male 10/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Disorder Other Serious 10/24/2008 75 Female 10/23/2009 United Kingdom
Primary
Concomitant
Multiple Drug Overdose Hospitalization 1/13/2009 61 Male 10/29/2009 Physician France
Primary
Secondary
Concomitant
Tremor Other Serious 59 Female 157 lb 10/29/2009 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/7/2008 56 Female 10/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 59 Female 157 lb 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization Female 11/12/2009 Consumer United Kingdom
Primary
Concomitant
Salivary Hypersecretion Hospitalization 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 194 lb 11/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/13/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/19/2009
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/5/2004 Male 12/2/2009 Physician Australia
Primary
Concomitant
Death Death Male 12/1/2009 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2009 Male 12/9/2009 Pharmacist United Kingdom
Primary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 194 lb 12/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 86 Female 12/7/2009 Denmark
Primary
Concomitant
Grand Mal Convulsion Other Serious 68 Female 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Mental Disorder Hospitalization Male 12/18/2009 United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 194 lb 1/4/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 1/13/2010 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 76 Female 1/11/2010 Physician United Kingdom
Primary
Concomitant
Heart Rate Increased Hospitalization 8/13/2009 Female 1/15/2010 Physician United Kingdom
Primary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 1/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 1/21/2010 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 11/8/2001 70 Male 1/15/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 2/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/5/2008 63 Female 2/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/5/2008 63 Female 3/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 Male 3/30/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/25/2010 61 Male 198 lb 4/5/2010
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 4/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2001 45 Male 4/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Other Serious 75 Male 4/9/2010
Primary
Secondary
Concomitant

Drug Data