Aspirin combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 4/22/2005 Female 162 lb 3/7/2006 Physician United States
Primary
Concomitant
Hypothyroidism Hospitalization 3/27/2006 Male 144 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 1/19/2006 58 Male Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/13/2006 78 Male Pharmacist United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 3/24/2006 52 Male 292 lb 3/27/2006 Pharmacist United States
Primary
Concomitant
Wheelchair User Disability 45 Male 243 lb 5/22/2006 United Kingdom
Primary
Concomitant
Urine Ketone Body Present Required Intervention 5/20/2003 28 Female 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 5/28/2006 Female 159 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/24/2006 56 Male 238 lb 9/8/2006 Physician United States
Primary
Concomitant
Tinnitus Hospitalization 8/24/2006 56 Male 238 lb 9/11/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/25/2006
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 67 Male 10/6/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/26/2006 69 Male 221 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Other Serious 3/31/2004 56 Female 225 lb 10/12/2006 Physician United States
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Microcytic Anaemia Other Serious 6/23/2006 17 Female 132 lb 10/23/2006 Physician United States
Primary
Secondary
Cholelithiasis Hospitalization 5/29/2006 Female 159 lb 11/20/2006 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 1/11/2007 47 Female 1/16/2007 Pharmacist United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2006 Female 111 lb 1/19/2007 Physician United States
Primary
Concomitant
Hepatitis Life Threatening 12/13/2004 Female 1/16/2007 Canada
Primary
Secondary
Concomitant
Wheezing Required Intervention 25 Male 3/19/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence 1/1/2006 86 Male 7/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Paraesthesia Disability 67 Female 9/5/2007 Physician
Primary
Concomitant
Visual Disturbance Disability 2/19/2007 67 Female 181 lb 9/12/2007 Physician
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 51 Male 167 lb 9/13/2007 Consumer United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/29/2007 52 Female 321 lb 9/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 12/8/2007 50 Female 178 lb 12/26/2007 United States
Primary
Concomitant
Weight Decreased Life Threatening 6/1/2002 49 Female 127 lb 1/14/2008 Consumer United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 11/1/2006 62 Female 11/29/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 6/1/2002 49 Female 127 lb 2/25/2008 Consumer United Kingdom
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 4/1/2008 57 Male 223 lb 5/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sciatica Female 157 lb 6/12/2008 United States
Primary
Concomitant
Pain 5/11/2008 Female 250 lb 6/13/2008 United States
Primary
Concomitant
Nasal Congestion 8/27/2008 61 Male 10/14/2008 Consumer United States
Primary
Concomitant
Poisoning Life Threatening 10/1/2004 67 Male 10/28/2008 Physician Mexico
Primary
Concomitant
Head Injury Hospitalization 4 Male 29 lb 11/26/2008 Italy
Primary
Secondary
Completed Suicide Death 39 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/8/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 39 Female 1/16/2009 United States
Primary
Secondary
Rash Disability 6/1/2008 73 Female 1/13/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 39 Female 1/23/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 39 Female 1/23/2009 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 1/28/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 39 Female 1/26/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 1/1/2008 Female 2/4/2009 Consumer Brazil
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2007 39 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 4/22/2005 Female 162 lb 2/9/2009 Physician United States
Primary
Concomitant
Respiratory Arrest Death 39 Female 3/5/2009 Physician United States
Primary
Secondary
Sudden Cardiac Death Other Serious 11/1/2008 34 Male 247 lb 3/9/2009 Physician South Africa
Primary
Concomitant
Product Substitution Issue Other Serious 4/15/2009 65 Female 155 lb 4/16/2009 Other Health Professional United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2001 42 Male 240 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 2/28/2006 45 Male 228 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Kidney Duplex Congenital Anomaly Female 6 lb 7/24/2009 Physician Australia
Primary
Secondary
Concomitant
Kidney Duplex Congenital Anomaly Female 6 lb 7/27/2009 Physician Australia
Primary
Secondary
Concomitant
Headache 8/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2009 61 Male 8/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 8/28/2009 84 Male 163 lb 9/17/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 6/1/2009 48 Female 9/18/2009 Pharmacist United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/20/2004 46 Male 234 lb 10/5/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2009 Female 213 lb 10/12/2009 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2009 51 Female 135 lb 10/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2009 Female 213 lb 10/13/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/22/2008 57 Male 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 6/1/2002 49 Female 127 lb 10/19/2009 United Kingdom
Primary
Concomitant
Weight Decreased Life Threatening 6/1/2002 49 Female 127 lb 10/27/2009 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 11/4/2009 Physician Czech Republic
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 8/1/2009 51 Female 135 lb 11/9/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 38 Male 11/10/2009 Pharmacist United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 11/23/2009 Physician Czech Republic
Primary
Concomitant
Arthralgia 1/1/2008 61 Female 185 lb 12/2/2009 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 12/7/2009 Physician Czech Republic
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2009 Female 230 lb 12/18/2009 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 12/23/2009 Physician Czech Republic
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/2/2009 34 Female 254 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2002 Female 127 lb 1/18/2010 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 1/29/2010 Physician Czech Republic
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 3/2/2010 Physician Czech Republic
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 4/28/2010 United States
Primary
Concomitant
Tremor Other Serious 63 Female 4/21/2010 United States
Primary
Secondary
Wheezing Hospitalization 11/1/2009 39 Female 6/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 5/8/2010 76 Female 6/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 7/1/2010 United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 1/1/2007 57 Male 232 lb 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 7/19/2010 United States
Primary
Concomitant
Convulsion Life Threatening 2/20/2010 62 Female 7/8/2010 United States
Primary
Concomitant
Mouth Ulceration Other Serious 5/8/2010 76 Female 8/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 51 Female 106 lb 8/20/2010 United States
Primary
Secondary
Concomitant
Rash 6/1/2010 64 Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 10/5/2009 43 Female 165 lb 9/20/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 10/1/2002 41 Female 225 lb 9/20/2010 United States
Primary
Concomitant
Oedema Peripheral 8/1/2010 54 Female 229 lb 9/23/2010 Consumer United States
Primary
Concomitant
Trigeminal Neuralgia Other Serious 1/1/2007 57 Female 232 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 49 Female 10/4/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 49 Female 10/13/2010
Primary
Secondary
Ureteric Obstruction Other Serious 49 Female 10/11/2010 Physician United States
Primary
Concomitant
Ventricular Tachycardia Required Intervention 7/1/2010 56 Female 197 lb 10/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Fungal Infection 64 Female 10/13/2010 Consumer United States
Primary
Concomitant
Torsade De Pointes Life Threatening 6/13/2010 78 Female 11/10/2010 Physician Spain
Primary
Concomitant
Ureteric Obstruction Other Serious 49 Female 11/15/2010 Physician United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 6/1/2010 64 Male 10/29/2010 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 46 Female 200 lb 12/1/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Dose Omission Other Serious Male 12/20/2010 Consumer Germany
Primary
Secondary
Cough 9/1/2010 53 Female 175 lb 12/28/2010 Consumer United States
Primary
Concomitant
Fatigue Other Serious 10/1/2009 62 Female 241 lb 1/4/2011 Consumer United States
Primary
Concomitant
Arthritis Other Serious 1/1/2007 54 Female 220 lb 12/29/2010 Consumer United States
Primary
Secondary
Concomitant
Restless Legs Syndrome Other Serious Male 1/7/2011 Lawyer United States
Primary
Concomitant
Constipation Other Serious 1/1/2010 54 Female 175 lb 1/21/2011 Physician United States
Primary
Concomitant
Hyperammonaemic Encephalopathy Hospitalization 7/17/2010 79 Male 1/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Secretion Life Threatening 62 Female 297 lb 2/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Secretion Discharge Required Intervention 62 Female 2/14/2011 United States
Primary
Secondary
Concomitant
Premature Separation Of Placenta Other Serious Female 3/9/2011 Pharmacist United States
Primary
Concomitant
Anxiety Disorder Other Serious 1/1/2007 48 Female 124 lb 3/24/2011 Physician United States
Primary
Concomitant
Interacting
Leukoencephalopathy Other Serious 71 Male 3/23/2011 Physician Germany
Primary
Secondary
Concomitant
Persecutory Delusion Life Threatening 58 Male 3/29/2011 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 2/10/2011 42 Male 4/11/2011 Physician Germany
Primary
Concomitant
Hypercalcaemia Other Serious 2/15/2011 48 Male 4/6/2011 Consumer Germany
Primary
Concomitant
Restless Legs Syndrome Other Serious 1/1/2007 49 Female 124 lb 4/6/2011 United States
Primary
Secondary
Concomitant
Hallucination, Auditory Life Threatening Male 4/6/2011 Physician Japan
Primary
Secondary
Concomitant
Psychotic Disorder Due To A General Medical Condition Life Threatening 1/1/2011 58 Male 4/11/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/18/2011 70 Male 4/26/2011 Physician Japan
Primary
Concomitant
Hypotension Other Serious 8/1/2010 45 Female 236 lb 5/3/2011 Consumer United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/18/2011 72 Male 5/3/2011 Physician Japan
Primary
Concomitant
Amnestic Disorder Other Serious 71 Male 5/3/2011 Physician Germany
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/1/2011 33 Female 271 lb 5/13/2011 Physician United States
Primary
Concomitant
Long Qt Syndrome Other Serious 62 Female 297 lb 5/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/1/2007 37 Female 181 lb 5/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 62 Female 5/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 62 Female 5/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/20/2011 72 Male 5/31/2011 Physician Japan
Primary
Concomitant
Cardiac Arrest Life Threatening 62 Female 298 lb 6/2/2011 Physician United States
Primary
Secondary
Cardiac Arrest Other Serious 62 Female 6/3/2011 United States
Primary
Secondary
Concomitant
Epilepsy Other Serious 4/20/2011 72 Male 6/16/2011 Physician Japan
Primary
Concomitant
Speech Disorder 2/7/2011 70 Female 197 lb 6/17/2011 Consumer United States
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 62 Female 298 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Depression Hospitalization 4/1/2009 37 Female 181 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Platelet Disorder Other Serious 7/30/2010 24 Female 7/8/2011 United States
Primary
Secondary
Concomitant
Mobility Decreased Other Serious 2/7/2011 70 Female 197 lb 7/11/2011 Consumer United States
Primary
Secondary
Concomitant
Grunting Other Serious 2/7/2011 70 Female 197 lb 7/15/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue 7/1/2011 60 Female 180 lb 7/26/2011 Consumer United States
Primary
Concomitant
Balance Disorder Other Serious 2/7/2011 70 Female 197 lb 7/28/2011 Physician United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 7/24/2011 70 Female 200 lb 8/5/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Female 156 lb 8/6/2011 Consumer United States
Primary
Concomitant
Weight Increased Male 242 lb 8/6/2011 Consumer United States
Primary
Concomitant
Ill-defined Disorder Female 160 lb 8/6/2011 Consumer United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 10/5/2009 43 Female 165 lb 8/8/2011 United States
Primary
Concomitant
Vomiting Hospitalization 1/14/2011 20 Male 165 lb 8/11/2011 Consumer United States
Primary
Concomitant

Drug Data