Aspirin combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting 6/28/2005 64 Female 148 lb 10/14/2005 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 9/13/2005 Female 9/14/2005 Pharmacist United States
Primary
Concomitant
Blood Sodium Decreased Hospitalization 7/12/2005 78 Female 1/30/2006 Consumer Italy
Primary
Concomitant
Vomiting Other Serious 11/30/2005 85 Female 143 lb 12/9/2005 Pharmacist United States
Primary
Concomitant
Road Traffic Accident Hospitalization 7/1/2002 46 Male 220 lb 2/10/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 9/9/2005 74 Female 11/3/2005 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2005 82 Female 120 lb 1/28/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/22/2006 85 Female 153 lb 2/22/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2005 82 Female 120 lb 1/28/2006 Pharmacist United States
Primary
Concomitant
Gait Disturbance 1/18/2006 61 Male 4/7/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 53 Female 4/13/2006 United States
Primary
Concomitant
Hypothyroidism Hospitalization 3/27/2006 Male 144 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/6/2005 22 Male 155 lb 12/26/2005 Pharmacist United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Required Intervention 3/25/2006 73 Male 196 lb 4/3/2006 United States
Primary
Concomitant
Platelet Count Decreased 4/12/2006 54 Female 5/12/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperammonaemia Required Intervention 79 Male 8/29/2005 Other Health Professional United States
Primary
Concomitant
Insomnia 1/1/2005 59 Female 130 lb 4/3/2006 Consumer United States
Primary
Concomitant
Hypotension Other Serious 5/8/2006 80 Male 166 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Death 7/1/2006 Male 308 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Drug Screen Positive Male 5/24/2006 Consumer United States
Primary
Concomitant
Vertigo Other Serious 1/1/1990 Male 165 lb 8/15/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2000 51 Male 228 lb 8/16/2006 Physician United States
Primary
Concomitant
Eczema Other Serious 96 Male 8/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Petit Mal Epilepsy Other Serious 45 Male 8/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2000 51 Male 228 lb 9/6/2006 Physician United States
Primary
Concomitant
Death Death 35 9/18/2006 Physician United States
Primary
Secondary
Drug Interaction Other Serious 55 Male 9/21/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Epilepsy Other Serious 9/11/2006 84 Female 9/21/2006 Physician Japan
Primary
Concomitant
Drug Toxicity Hospitalization 77 Male 9/27/2006 Physician Spain
Primary
Concomitant
Interacting
Wound Secretion Other Serious 9/8/2006 80 Male 152 lb 9/22/2006 Other Health Professional United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Vascular Bypass Graft Other Serious 3/1/2006 45 Male 176 lb 9/26/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2005 81 Male 247 lb 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 9/8/2006 80 Male 335 lb 10/6/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 10/31/2006 60 Female 11/13/2006 Pharmacist Japan
Primary
Concomitant
Drug Toxicity Death 1/1/2005 35 NotSpecified 11/21/2006 Physician United States
Primary
Secondary
Hepatotoxicity Other Serious 6/14/2006 78 Male 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urine Ketone Body Present Other Serious 12/1/2005 Female 12/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 12/27/2006 89 Female 1/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 12/27/2006 89 Female 2/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 1/3/2007 Female 148 lb 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Sedation Other Serious 9/1/2006 46 Male 225 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Ocular Hyperaemia Disability 2/1/2007 80 Male 3/5/2007 Pharmacist Ireland
Primary
Concomitant
Wound Drainage Other Serious 9/8/2006 80 Male 152 lb 3/9/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/15/2007 77 Female 190 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 59 Female 4/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 4/10/2007 United Kingdom
Primary
Secondary
Concomitant
Type Iia Hyperlipidaemia Required Intervention 61 Male 4/17/2007 Physician Canada
Primary
Concomitant
Multiple Drug Overdose Intentional Death 61 Male 5/8/2007 Physician United States
Primary
Secondary
Asthenia Hospitalization 3/22/2007 Male 153 lb 5/10/2007 Pharmacist United States
Primary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 5/16/2007 United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 12/1/2006 54 Male 6/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 2/24/2001 Male 6/27/2007 Consumer United States
Primary
Concomitant
Pneumonia Death 71 Male 115 lb 7/6/2007 Physician Japan
Primary
Concomitant
Drug Toxicity Hospitalization 78 Female 7/20/2007 Physician Ireland
Primary
Secondary
Concomitant
Pathological Fracture Hospitalization 7/1/2007 Female 7/20/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/1/2007 Male 180 lb 7/23/2007 Physician United States
Primary
Concomitant
Lipids Abnormal Other Serious 61 Male 7/31/2007 Canada
Primary
Concomitant
Interacting
Pathological Fracture Hospitalization 7/1/2007 Female 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Middle Insomnia 1/1/2007 81 Female 200 lb 7/10/2007 Consumer United States
Primary
Concomitant
Incorrect Dose Administered Hospitalization 78 Female 8/3/2007 Ireland
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 8/21/2007 Ireland
Primary
Secondary
Interacting
Upper Gastrointestinal Haemorrhage Life Threatening 1/10/2007 82 Male 217 lb 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 65 Male 9/4/2007 United Kingdom
Primary
Concomitant
Tremor Other Serious 2/1/2001 Male 135 lb 10/19/2007 Consumer United States
Primary
Concomitant
Somnolence Required Intervention 9/12/2007 51 Male 179 lb 10/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Muscle Spasms 10/3/2006 72 Female 10/25/2007 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 93 Male 10/31/2007 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 20 Male 11/9/2007 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 2/1/2001 Male 135 lb 11/9/2007 Consumer United States
Primary
Concomitant
Sepsis Death 20 Male 11/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/2/2007 76 Female 105 lb 11/8/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/17/2007 81 Female 11/20/2007 Physician Japan
Primary
Concomitant
Somnolence Death 20 Male 11/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 1/1/2006 49 Male 10/22/2007 United States
Primary
Concomitant
Vasoconstriction Other Serious 10/22/2007 81 Female 12/3/2007 Physician Japan
Primary
Secondary
Concomitant
Tumour Haemorrhage Life Threatening 4/15/2007 71 Male 115 lb 12/7/2007 Physician Japan
Primary
Concomitant
Rash Generalised Other Serious 10/23/2007 67 Female 12/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 11/15/2007 70 Female 12/17/2007 Consumer United Kingdom
Primary
Concomitant
Blood Triglycerides Increased 7/1/2007 59 Female 175 lb 12/17/2007 United States
Primary
Concomitant
Incorrect Dose Administered Hospitalization 78 Female 12/27/2007 Ireland
Primary
Concomitant
Loss Of Consciousness Required Intervention 70 Female 1/7/2008 Physician Canada
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/29/2006 70 Female 1/17/2008
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 11/15/2007 Male 165 lb 1/18/2008 Physician United Kingdom
Primary
Concomitant
Vertigo Other Serious 7/2/2007 88 Male 1/23/2008 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 7/2/2007 88 Male 2/7/2008 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Hospitalization 78 Female 2/11/2008 Physician Ireland
Primary
Secondary
Concomitant
Vertigo Other Serious 7/2/2007 88 Male 2/12/2008 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Hospitalization 78 Female 2/13/2008 Physician Ireland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 1/15/2008 79 Female 220 lb 2/19/2008 Consumer United Kingdom
Primary
Concomitant
Pustular Psoriasis Other Serious 11/25/2007 52 Male 2/22/2008 Other Health Professional Singapore
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 1/1/2004 Female 240 lb 2/25/2008 United States
Primary
Secondary
Concomitant
Interacting
Drug Interaction Hospitalization 1/1/2007 70 Female 2/21/2008 Physician Canada
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 11/15/2007 Male 165 lb 3/1/2008 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Renal Failure Acute Life Threatening 1/15/2008 79 Female 220 lb 2/29/2008 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 65 Male 3/10/2008 Pharmacist United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Cardiac Failure Congestive Hospitalization 3/27/2006 Male 144 lb 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/19/2008 77 Female 155 lb 4/1/2008 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 4/10/2008 Physician Germany
Primary
Secondary
Loss Of Consciousness Hospitalization 5/29/2006 70 Female 4/9/2008 Physician Canada
Primary
Concomitant
Drug Level Decreased Life Threatening 4/1/2008 61 Male 170 lb 4/9/2008 Pharmacist United States
Primary
Concomitant
Tearfulness Other Serious 7/3/2002 57 Female 5/5/2008 Physician United Kingdom
Primary
Concomitant
Skin Papilloma Other Serious 1/26/2007 30 Female 4/28/2008 Physician France
Primary
Concomitant
Nausea 5/10/2008 Female 137 lb 5/22/2008 United States
Primary
Concomitant
Neutropenia Disability 4/1/2008 56 Male 130 lb 5/27/2008 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 Female 6/4/2008 Lawyer United States
Primary
Secondary
Concomitant
Cellulitis 4/10/2008 Female 248 lb 6/12/2008 United States
Primary
Concomitant
Muscular Weakness 4/27/2008 Female 238 lb 6/13/2008 United States
Primary
Concomitant
Transaminases Increased Other Serious 10/10/2003 Female 6/13/2008 France
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 4/21/2008 60 Male 5/2/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Death 5/10/2008 Female 104 lb 6/19/2008 Physician United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 3/14/2008 64 Female 6/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Musculoskeletal Discomfort Disability 6/2/2008 81 Female 176 lb 7/8/2008 Other Health Professional United Kingdom
Primary
Concomitant
Heart Rate Increased 9/1/2007 65 Female 7/24/2008 Consumer United States
Primary
Concomitant
Tearfulness Other Serious 7/3/2002 57 Female 7/28/2008 Physician United Kingdom
Primary
Concomitant
Vomiting Life Threatening 46 Female 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/31/2008 65 Female 143 lb 7/7/2008 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 6/4/2008 64 Male 9/3/2008 Pharmacist United States
Primary
Concomitant
Tearfulness Other Serious 7/3/2002 57 Female 9/12/2008 Physician United Kingdom
Primary
Concomitant
Stomach Discomfort Other Serious 2/1/2001 Male 130 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Postnasal Drip Other Serious 1/1/2006 Male 10/22/2008 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 2/24/2001 60 Male 130 lb 11/26/2008 Consumer United States
Primary
Concomitant
Interacting
Stevens-johnson Syndrome Other Serious 12/1/2005 48 Female 12/17/2008 Physician Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Death 7/1/2005 39 Female 2/3/2009 Other Health Professional Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2000 59 Male 2/6/2009 Physician New Zealand
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 11/1/2000 59 Male 2/10/2009 Physician New Zealand
Primary
Concomitant
Epilepsy Hospitalization 1/13/2009 2/18/2009 Physician Switzerland
Primary
Secondary
Concomitant
Dizziness Hospitalization 2/11/2009 80 Male 141 lb 3/2/2009 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 69 Male 3/24/2009 Other Health Professional United States
Primary
Secondary
Pleural Effusion Other Serious 2/3/2009 25 Male 3/27/2009 Other Health Professional Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/2/2005 4/2/2009 Physician Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 1/19/2009 77 Male 183 lb 3/31/2009 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/2/2005 Female 4/7/2009 Physician Germany
Primary
Secondary
Concomitant
Petit Mal Epilepsy Other Serious 3/1/2006 45 Male 176 lb 4/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 50 Male 4/23/2009 Physician United States
Primary
Concomitant
Laceration Hospitalization 3/17/2009 72 Male 194 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 25 Male 6/3/2009 Other Health Professional Japan
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1995 40 Male 193 lb 6/11/2009 United States
Primary
Concomitant
Post Procedural Complication Hospitalization 3/1/2009 53 Male 6/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Required Intervention 4/16/2009 49 Female 130 lb 4/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 50 Male 6/25/2009 Pharmacist United States
Primary
Concomitant
Gastrointestinal Ulcer Haemorrhage Hospitalization Female 195 lb 7/21/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2009 53 Male 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/9/2009 81 Female 210 lb 7/31/2009 Consumer United States
Primary
Concomitant

Drug Data