Aspirin combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiratory Failure Hospitalization 2/23/2005 Female 121 lb 1/3/2006 Other Health Professional
Primary
Secondary
Concomitant
Interacting
Thrombosis Hospitalization 1/20/2001 Male 1/3/2006 France
Primary
Concomitant
Hyponatraemia Hospitalization 7/13/2001 Female 1/4/2006 Finland
Primary
Concomitant
Skin Ulcer Hospitalization 2/13/2002 Female 1/4/2006 France
Primary
Concomitant
Right Ventricular Failure Hospitalization 8/14/2001 Female 1/4/2006 New Zealand
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 2/20/2002 Female 1/4/2006 Finland
Primary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 12/30/2005 Physician United States
Primary
Concomitant
Coronary Ostial Stenosis Hospitalization 11/21/2005 71 Male 192 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 1/4/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Surgery Hospitalization 4/12/2005 46 Male 192 lb 1/4/2006 United Kingdom
Primary
Secondary
Concomitant
Exercise Test Abnormal Hospitalization 6/7/2005 68 Male 1/5/2006 Physician United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 12/12/2005 Female 176 lb 1/12/2006 Physician China
Primary
Concomitant
Visual Acuity Reduced Other Serious 79 Male 1/12/2006 Consumer United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 2/9/2005 69 Male 4/4/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/19/2005 Male 1/13/2006 Italy
Primary
Secondary
Concomitant
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
Ulnar Nerve Injury Hospitalization 8/4/1999 56 Male 300 lb 1/17/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 62 Female 187 lb 1/17/2006 Lawyer United States
Primary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 12/1/2005 70 Female 126 lb 1/19/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 11/19/2005 73 Male 1/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Rhabdomyolysis Death 11/19/2005 Male 1/19/2006 Italy
Primary
Secondary
Concomitant
Extrasystoles Other Serious 12/1/2005 Male 1/20/2006 Physician Sweden
Primary
Concomitant
Staphylococcal Infection Life Threatening 10/15/2005 64 Male 109 lb 1/18/2006 Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 10/20/2005 64 161 lb 1/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypotension Other Serious 1/1/2001 64 Male 209 lb 1/24/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2000 83 Female 99 lb 1/25/2006 United Kingdom
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 8/10/2004 50 Male 1/25/2006 Physician Brazil
Primary
Concomitant
Unevaluable Event Hospitalization 11/1/2005 86 Female 1/17/2006 Other Health Professional Japan
Primary
Concomitant
Pericardial Effusion Hospitalization 9/5/2005 58 Female 1/18/2006 Physician United Kingdom
Primary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/4/2005 73 Male 1/27/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Rectal Polyp Hospitalization 8/14/2005 64 Female 154 lb 1/20/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2001 80 Female 146 lb 1/30/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 9/23/2005 72 Male 176 lb 1/30/2006 Physician
Primary
Concomitant
Myocardial Infarction Life Threatening 12/1/2005 70 Female 126 lb 1/30/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Death 61 Male 1/23/2006 Philippines
Primary
Concomitant
Hyponatraemia Other Serious 12/21/2005 70 Male 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 1/3/2006 81 Male 176 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 7/30/2004 Male 1/27/2006 Physician Sweden
Primary
Secondary
Concomitant
Obesity Other Serious 10/1/2005 46 Male 2/1/2006 Physician United Kingdom
Primary
Concomitant
Nitritoid Crisis Other Serious 8/22/2002 63 Male 2/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonitis Death 6/1/2005 69 Male 1/30/2006 United Kingdom
Primary
Concomitant
Cerebral Infarction Hospitalization 7/1/2005 62 Male 2/3/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/30/2005 Male 153 lb 1/3/2006 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Hospitalization 11/19/2005 Male 208 lb 1/3/2006 Pharmacist United States
Primary
Concomitant
Pneumonitis Death 6/1/2005 69 Male 2/6/2006 United Kingdom
Primary
Concomitant
Skin Test Positive Life Threatening 8/6/2005 Male 112 lb 2/13/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/8/2002 59 Male 203 lb 2/13/2006 Physician United States
Primary
Concomitant
Dizziness Postural Hospitalization 10/12/2005 Male 144 lb 10/13/2005 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Vasovagal Other Serious 8/22/2002 63 Male 2/8/2006 Other Health Professional
Primary
Concomitant
Weight Increased Hospitalization 7/5/2004 59 Female 2/8/2006 Physician Japan
Primary
Concomitant
Ischaemic Stroke Hospitalization 9/1/2004 77 Female 190 lb 2/16/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 12/9/2004 73 Male 118 lb 2/9/2006 Physician Japan
Primary
Concomitant
Peritonitis Bacterial Hospitalization 1/25/2005 74 118 lb 5/23/2005 Physician Japan
Primary
Concomitant
Procedural Complication Hospitalization 10/6/2004 73 Male 118 lb 5/18/2005 Physician Japan
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Myocardial Infarction Other Serious 5/15/2003 76 Female 77 lb 2/21/2006 Lawyer United Kingdom
Primary
Concomitant
Nightmare Disability 8/1/2005 69 Male 2/20/2006 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2003 89 Female 141 lb 2/22/2006 Physician United States
Primary
Concomitant
Panic Attack Hospitalization Female 2/15/2006 United Kingdom
Primary
Concomitant
Stomach Discomfort Life Threatening 5/20/2005 Male 146 lb 2/23/2006 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 12/6/2005 81 Male 154 lb 2/15/2006 Poland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/16/2006 Poland
Primary
Secondary
Concomitant
Drug Hypersensitivity Life Threatening 8/6/2005 Male 112 lb 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 2/24/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/12/2005 Female 2/28/2006 Consumer United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 5/9/2005 77 Male 220 lb 2/21/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 62 Male 2/22/2006 Physician United Kingdom
Primary
Concomitant
Asthma Other Serious 1/15/2006 54 Female 179 lb 3/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 8/1/2001 76 Female 99 lb 3/2/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/1/2003 89 Female 141 lb 3/3/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 12/19/2005 77 Female 115 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 5/9/2005 77 Male 220 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/1999 73 Female 165 lb 3/6/2006 Lawyer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/8/2006 70 Female 3/10/2006 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 75 Female 3/6/2006 Pharmacist Japan
Primary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/7/2006 United Kingdom
Primary
Concomitant
Vertebral Artery Stenosis Other Serious 2/1/2001 60 Female 3/14/2006 Physician United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 3/16/2006 Physician United States
Primary
Concomitant
Rash Pruritic Other Serious 1/30/2005 75 Female 165 lb 12/21/2005 Consumer United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/4/2003 Female 3/17/2006 Physician United States
Primary
Concomitant
Oedema Due To Cardiac Disease Hospitalization 7/1/2005 60 Female 119 lb 3/10/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 12/13/2005 74 Male 84 lb 3/10/2006 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 3/21/2006 Physician United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/1/2006 70 Female 3/15/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Troponin T Increased Hospitalization 3/2/2005 77 Male 134 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Cancer Life Threatening 5/9/2005 77 Male 220 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Oedema Peripheral Disability 2/16/2006 67 Female 3/3/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 2/15/2006 59 Male 220 lb 3/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/15/2006 Singapore
Primary
Concomitant
Coronary Artery Disease Death 12/1/2003 72 Male 3/28/2006 Physician United States
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/22/2006 Physician Singapore
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/21/2006 Physician Singapore
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 6/1/2000 66 Female 157 lb 3/31/2006 Physician United States
Primary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 3/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Osteoarthritis Hospitalization 1/1/2003 60 Female 150 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Tinnitus Hospitalization 2/1/2001 60 Female 161 lb 4/4/2006 Physician United States
Primary
Concomitant
Visual Disturbance 10/7/2005 Male 201 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Hospitalization 11/29/2005 89 Male 3/29/2006 Japan
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/9/2005 76 Female 183 lb 4/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Exfoliation Other Serious 3/2/2006 61 Male 4/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Other Serious 3/11/2006 72 Male 4/12/2006 Consumer United States
Primary
Concomitant
Myalgia Other Serious 1/16/2006 66 Male 4/12/2006 Physician Japan
Primary
Concomitant
Coronary Artery Disease Hospitalization 1/22/2005 76 Male 185 lb 4/6/2006 Czech Republic
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 2/1/2001 60 Female 161 lb 4/14/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 4/17/2006 Physician United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/4/2003 72 Female 4/18/2006 Physician United States
Primary
Concomitant
Vertigo Hospitalization 2/1/2006 92 Male 4/11/2006 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 3/1/2006 68 Male 154 lb 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 2/26/2006 64 Female 195 lb 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/24/2004 67 Male 165 lb 4/24/2006 Physician United States
Primary
Concomitant
Weight Increased 9/14/2005 63 Female 225 lb 4/14/2006 Physician United States
Primary
Concomitant
Hallucination, Visual Hospitalization 10/28/2005 79 Male 148 lb 4/18/2006 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2004 60 Male 4/25/2006 Brazil
Primary
Concomitant
Pharyngeal Oedema Hospitalization 12/29/2005 66 Male 4/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Spinal Column Stenosis Hospitalization 10/31/2003 59 Female 190 lb 5/2/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/29/2000 60 Female 181 lb 5/3/2006 Physician United States
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 4/26/2006 Physician Japan
Primary
Secondary
Concomitant
Alopecia 1/1/2006 85 Female 2/17/2006 Consumer United States
Primary
Concomitant
Rhinitis Allergic Hospitalization 4/1/2003 49 Male 218 lb 5/5/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 2/27/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2005 Male 5/8/2006 Physician Sweden
Primary
Concomitant
Wound Infection Bacterial Other Serious 4/13/2006 69 Female 165 lb 5/5/2006 United States
Primary
Secondary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Sick Sinus Syndrome Other Serious 1/1/2001 64 Male 209 lb 5/11/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 4/1/2006 67 Female 5/11/2006 Consumer United States
Primary
Concomitant
Arthralgia Other Serious 4/3/2006 49 Female 181 lb 5/11/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 2/20/2006 65 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/22/2005 87 Male 5/1/2006 Physician United Kingdom
Primary
Concomitant
Myopathy Hospitalization 1/19/2006 79 Female 5/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anosmia Other Serious 1/29/2006 50 Male 35 lb 5/17/2006 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2004 72 Male 187 lb 5/11/2006 Physician India
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/1/2006 72 Female 121 lb 5/19/2006 Physician Japan
Primary
Concomitant
Myopathy Hospitalization 1/19/2006 79 Female 5/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 76 Male 154 lb 5/22/2006 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/6/2006 77 Male 154 lb 5/23/2006 Physician United Kingdom
Primary
Concomitant
Liver Disorder Life Threatening 4/4/2006 55 Male 5/23/2006 Physician France
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/5/2006 80 Female 5/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/1/2005 70 Female 126 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Life Threatening 12/22/2005 87 Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 1/6/2006 76 Male 172 lb 5/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fall Other Serious 2/1/2006 92 Male 5/23/2006 Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 12/13/2005 74 Male 84 lb 5/23/2006 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 4/1/2006 80 Male 5/26/2006 Physician Japan
Primary
Concomitant

Drug Data