Aspirin combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vasospasm Life Threatening 11/22/2005 62 Male 128 lb 12/29/2005 Pharmacist Japan
Primary
Concomitant
Vision Blurred Life Threatening 10/10/2005 Female 191 lb 10/11/2005 United States
Primary
Concomitant
Urinary Tract Infection Death 61 Male 1/23/2006 Philippines
Primary
Concomitant
Respiratory Arrest Life Threatening 1/4/2006 80 Male 1/25/2006 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 2/23/2005 64 Male 1/31/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 58 Male 2/3/2006 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram St Segment Depression Life Threatening 11/22/2005 62 Male 128 lb 1/23/2006 Pharmacist Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 11/3/2005 60 Male 185 lb 11/4/2005 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 11/3/2005 60 Male 188 lb 11/4/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2002 77 Female 110 lb 2/14/2006 Lawyer United States
Primary
Concomitant
Hyperhidrosis 10/18/2005 65 Female 2/15/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/1/1999 58 Male 2/15/2006 Consumer United States
Primary
Secondary
Concomitant
Bradycardia Life Threatening 12/15/2005 63 Female 2/8/2006 Physician Japan
Primary
Concomitant
Sensory Disturbance Life Threatening 1/4/2006 80 Male 2/1/2006 Physician Japan
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 2/13/2006 Japan
Primary
Concomitant
Weight Decreased Hospitalization 1/28/2006 75 Female 2/24/2006 Japan
Primary
Concomitant
Haematocrit Decreased Hospitalization 8/1/2004 70 Male 12/21/2005 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/28/2006 75 Female 3/10/2006 Japan
Primary
Concomitant
Cerebrovascular Accident Death 4/18/2004 55 Male 3/22/2006 Consumer Malaysia
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/24/2003 63 Male 150 lb 3/22/2006 Physician Germany
Primary
Concomitant
Tremor Other Serious 2/23/2002 46 Male 3/22/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 2/13/2006 71 Male 3/20/2006 Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/1999 77 Male 231 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2002 77 Female 110 lb 4/25/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Death 3/29/2006 72 Male 4/28/2006 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 2/25/2004 71 Male 201 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 1/1/2003 93 Female 5/10/2006 United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 8/28/2002 76 Male 5/19/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 76 Male 5/19/2006 Other Health Professional Japan
Primary
Concomitant
Interacting
Vomiting Hospitalization 1/1/1999 58 Male 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 1/1/2006 65 Male 5/19/2006 Physician Germany
Primary
Secondary
Concomitant
Sudden Death Other Serious 5/8/2006 89 Male 150 lb 5/26/2006 Physician Canada
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 8/28/2002 76 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Required Intervention 6/27/2005 77 Male 155 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Stomach Discomfort Hospitalization 1/1/2005 87 Male 134 lb 5/31/2006 United States
Primary
Concomitant
Myalgia Hospitalization 1/1/2006 65 Male 152 lb 6/14/2006 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/2/2005 71 Male 216 lb 6/27/2006 Other Health Professional Germany
Primary
Concomitant
Vomiting Life Threatening 4/1/2006 80 Female 6/23/2006 Physician Germany
Primary
Concomitant
Normochromic Normocytic Anaemia Hospitalization 2/13/2006 78 Female 6/26/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Meniscus Lesion Hospitalization 4/1/2005 Male 7/5/2006 Physician Korea, Republic Of
Primary
Concomitant
Thrombosis In Device Hospitalization 60 Male 207 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness 2/14/2006 66 Male 218 lb 4/17/2006 United States
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 2/1/2006 49 Female 253 lb 4/17/2006 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Restrictive Pulmonary Disease Other Serious 5/8/2006 84 Male 146 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 5/8/2006 84 Male 146 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 5/5/2006 56 Male Pharmacist United States
Primary
Concomitant
Hypoglycaemic Seizure Hospitalization 12/28/2005 71 Female 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Other Serious Male 119 lb 7/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 6/23/2006 45 Male 7/17/2006 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 4/26/2006 85 Male 200 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/2/2006 60 Male Pharmacist United States
Primary
Concomitant
Unevaluable Event Hospitalization 5/31/2006 65 Male Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/24/2006 70 Male Pharmacist United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 6/15/2006 88 Male 198 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Other Serious 5/31/2005 Male 119 lb 7/26/2006 Other Health Professional United Kingdom
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Electrocardiogram St Segment Depression Hospitalization 12/31/2005 84 Female 8/1/2006 Consumer Italy
Primary
Concomitant
Myocardial Ischaemia Hospitalization 4/1/2006 62 Male 7/26/2006 Other Health Professional United States
Primary
Concomitant
Pruritus Hospitalization 1/1/2005 Male 8/8/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2005 Male 215 lb 8/8/2006 Consumer United States
Primary
Concomitant
Middle Insomnia 85 Male 165 lb 7/12/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 74 Female 8/9/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 5/19/2005 Male 119 lb 8/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Therapy Non-responder Hospitalization 1/1/2001 67 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Medication Residue 64 Female 181 lb 8/14/2006 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/8/2006 78 Male 176 lb 8/15/2006 Bulgaria
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 68 Male 8/16/2006 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/1/2006 69 Male 150 lb 8/18/2006 United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 5/21/2006 65 Male 185 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 3/29/2006 62 Male 8/24/2006 Malaysia
Primary
Secondary
Concomitant
Inguinal Hernia Other Serious 5/7/2005 69 Male 151 lb 8/31/2006 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 64 Female 9/5/2006 Malaysia
Primary
Secondary
Tachycardia Hospitalization 2/13/2006 78 Female 171 lb 9/6/2006 Germany
Primary
Secondary
Concomitant
Pruritus Other Serious 8/10/2006 52 Female 115 lb 9/6/2006 Germany
Primary
Concomitant
Renal Failure Acute Death Male 9/15/2006 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Hospitalization 6/22/2006 47 Male 203 lb 9/13/2006 United States
Primary
Secondary
Concomitant
Urinary Incontinence Required Intervention 7/26/2006 55 Male 187 lb 9/21/2006 France
Primary
Secondary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Arthralgia Other Serious 5/10/2006 40 Male 192 lb 9/29/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Sepsis Hospitalization 9/15/2006 75 Male 172 lb 10/2/2006 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2005 81 Male 247 lb 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/3/2005 85 Male 150 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Subileus Hospitalization 12/28/2004 85 Female 150 lb 10/4/2006 Other Health Professional Germany
Primary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Periarthritis Disability 7/1/2006 88 Male 9/28/2006 Physician United Kingdom
Primary
Concomitant
Pruritus Other Serious 8/10/2006 52 Female 115 lb 10/3/2006 Physician Germany
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Weight Increased Other Serious 1/1/2006 68 Male 10/16/2006 Consumer Japan
Primary
Concomitant
Sepsis Other Serious 9/15/2006 75 Male 172 lb 10/26/2006 Physician Germany
Primary
Concomitant
Pruritus Other Serious 8/25/2006 69 Male 10/20/2006 Physician Japan
Primary
Secondary
Concomitant
Bronchopneumonia Life Threatening 2/4/2006 57 Female 11/2/2006 Physician Germany
Primary
Concomitant
Pruritus Other Serious 8/25/2006 69 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 9/15/2006 75 Male 172 lb 11/3/2006 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 85 Female 11/29/2006 Other Health Professional Japan
Primary
Concomitant
Myalgia Other Serious 7/12/2006 58 Male 198 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 8/9/2006 76 Female 99 lb 12/4/2006 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/9/2006 63 Male 11/28/2006 Physician Lebanon
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/12/2006 81 Female 11/28/2006 Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Hospitalization 4/26/2005 78 Female 154 lb 12/11/2006 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Death 72 Female 227 lb 12/15/2006 Physician Germany
Primary
Concomitant
Weight Decreased Other Serious 8/9/2006 76 Female 12/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Scotoma Other Serious 1/1/2005 68 Male 12/15/2006 United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint 7/1/2006 80 Male 175 lb 12/28/2006 Consumer United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/20/2004 Female 12/28/2006 Physician Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/23/2006 65 Male 247 lb 10/21/2006 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Death Female 227 lb 1/5/2007 Physician Germany
Primary
Concomitant
Leukocytosis Hospitalization 11/15/2005 55 Female 1/5/2007 Physician Germany
Primary
Concomitant
Skin Cancer Other Serious 72 Male 250 lb 1/8/2007 Consumer United States
Primary
Concomitant
Pseudarthrosis Other Serious 3/1/2005 83 Female 1/12/2007 Other Health Professional Germany
Primary
Concomitant
Neurological Symptom Other Serious 72 Male 250 lb 1/9/2007 Consumer United States
Primary
Concomitant
Gastroenteritis Hospitalization 2/24/2005 78 Female 163 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Pulmonary Hypertension Life Threatening 8/30/2006 70 Female 150 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Shock Other Serious 9/15/2006 Male 172 lb 2/6/2007 Physician Germany
Primary
Concomitant
Splenomegaly Other Serious 58 Male 2/2/2007 Physician Turkey
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/10/2006 Male 215 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 5/10/2005 79 Male 165 lb 2/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 65 Female 190 lb 2/12/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/19/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/21/2007 Physician Poland
Primary
Concomitant
Drug Ineffective 75 Male 3/7/2007 Consumer United States
Primary
Concomitant
Shock Life Threatening 2/8/2007 3/5/2007 Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/18/2006 82 Male 154 lb 3/1/2007 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Other Serious 51 Male 3/21/2007 Australia
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 59 Female 4/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 9/9/2006 Male 294 lb 1/22/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Hospitalization 9/9/2006 Male 294 lb 1/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 8/14/2005 61 Male 4/12/2007 Physician France
Primary
Secondary
Concomitant
Nasopharyngitis 9/1/2006 74 Female 1/12/2007 Consumer United States
Primary
Concomitant
Hypokinesia Other Serious 74 Female 4/13/2007 Physician Japan
Primary
Concomitant
Ventricular Dysfunction Other Serious 74 Female 4/13/2007 Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Death 93 Female 4/11/2007 United Kingdom
Primary
Concomitant
Soft Tissue Disorder Hospitalization 11/11/2006 56 Male 4/19/2007 Physician China
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 11/23/2006 69 Male 251 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2004 52 Female 163 lb 5/4/2007 United States
Primary
Concomitant
Renal Failure Acute Other Serious 3/28/2007 75 Female 4/30/2007 Japan
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 5/14/2007 Physician Poland
Primary
Concomitant
Syncope Other Serious 1/1/2005 65 Female 190 lb 5/16/2007 Physician Poland
Primary
Concomitant
Neoplasm Hospitalization 11/11/2006 56 Male 5/15/2007 China
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 11/8/2006 84 Male 157 lb 2/28/2007 Physician United States
Primary
Concomitant

Drug Data