Aspirin combined with Clozapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Necrosis Other Serious 10/9/2005 51 Male 1/9/2006 France
Primary
Secondary
Concomitant
Diabetes Mellitus Insulin-dependent Hospitalization 11/4/2005 39 Male 1/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 9/17/2005 68 Female 2/20/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 9/17/2005 68 Female 2/24/2006 Physician Canada
Primary
Secondary
Concomitant
Troponin Increased Death 2/6/2006 58 Male 198 lb 3/3/2006 United Kingdom
Primary
Concomitant
Agranulocytosis Other Serious 2/24/2005 51 Male 3/22/2005 Pharmacist United States
Primary
Concomitant
Unevaluable Event Death 5/25/2005 83 Female 7/26/2005 Pharmacist United States
Primary
Concomitant
Neutrophil Count Decreased 2/27/2006 Male 175 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 61 Male 4/6/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/5/2006 69 Male 4/11/2006 Physician Slovenia
Primary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 5/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Posturing Life Threatening 3/21/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/9/2006 48 Male 207 lb 5/24/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 4/7/2006 81 Female 5/23/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/28/2005 39 Male 6/16/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/8/2006 61 Female 4/10/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/3/2006 46 Male 5/9/2006 United States
Primary
Concomitant
Leukopenia Required Intervention 11/2/2005 43 Male 196 lb 6/16/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 11/23/2005 55 Male 2/27/2006 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 2/10/2006 54 Female 6/1/2006 United States
Primary
Concomitant
Small Cell Carcinoma Death 7/26/2006 45 Female 8/31/2006 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/22/2006 46 Male 9/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Death 8/6/2006 81 Female 112 lb 9/11/2006 United States
Primary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 9/21/2006 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2006 46 Male 10/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2006 46 Male 10/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2006 46 Male 11/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Required Intervention 35 Male 11/7/2006 United States
Primary
Concomitant
Postictal State Other Serious 7/13/2006 42 Female 1/3/2007 United Kingdom
Primary
Concomitant
Hepatitis Life Threatening 12/13/2004 Female 1/16/2007 Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 9/11/2006 63 Male 2/22/2007 Physician Germany
Primary
Concomitant
Hysterectomy Other Serious 11/1/2006 43 Female 3/10/2007 United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Death 60 Female 5/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Speech Disorder Hospitalization 6/17/2007 75 Male 141 lb 7/2/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 6/17/2007 75 Male 141 lb 8/7/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/3/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/22/2006 46 Male 10/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 10/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Psychotic Disorder Death 6/1/2007 Male 195 lb 10/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 2/22/2006 46 Male 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/19/2007 77 Female 157 lb 10/19/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 2/22/2006 10/31/2007 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2007 33 Male 173 lb 3/4/2008 United States
Primary
Secondary
Concomitant
Paranoia Hospitalization 1/15/2008 58 Female 262 lb 4/7/2008 Physician Switzerland
Primary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/19/2008 Other Health Professional United States
Primary
Concomitant
Metastases To Breast Other Serious 3/1/2008 Female 6/27/2008 Other Health Professional United States
Primary
Concomitant
Overdose Hospitalization 6/6/2007 Male 148 lb 7/3/2008 Physician Germany
Primary
Concomitant
Drug Level Increased Hospitalization 1/1/2007 Male 141 lb 7/30/2008 Physician Germany
Primary
Secondary
Concomitant
Stress Other Serious 8/26/2008 Male 208 lb 9/10/2008 Physician United States
Primary
Concomitant
Wrong Drug Administered Hospitalization 63 Male 9/22/2008 Consumer Israel
Primary
Secondary
Concomitant
Pyrexia Hospitalization 33 Male 9/26/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 8/9/2008 Male 309 lb 10/27/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Stress Other Serious 8/26/2008 Male 208 lb 9/10/2008 Physician United States
Primary
Concomitant
Overdose Hospitalization 9/5/2008 51 Male 11/24/2008 Other Health Professional Denmark
Primary
Concomitant
Rash 9/1/2008 Male 12/16/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/3/2008 49 Male 212 lb 12/19/2008 Pharmacist United States
Primary
Concomitant
Eosinophilia 4/11/2009 59 Male 171 lb 4/23/2009 Pharmacist United States
Primary
Secondary
Vomiting Other Serious 44 Female 5/15/2009 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/24/2008 69 Female 6/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Duodenal Ulcer Haemorrhage Life Threatening 5/24/2008 69 Female 115 lb 6/18/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 44 Female 6/19/2009
Primary
Secondary
Concomitant
Peptic Ulcer Life Threatening 5/24/2008 69 Female 115 lb 6/17/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 7/1/2009 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 5/12/2007 41 Female 6/29/2009 Sweden
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/4/2006 59 Male 348 lb 7/31/2009 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 5/12/2007 42 Female 8/13/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hysterectomy Other Serious 11/1/2006 Female 8/25/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/1/2006 Female 9/10/2009 Physician United States
Primary
Concomitant
Somnolence Other Serious 3/29/2009 29 Male 9/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 10/14/2009 Other Health Professional France
Primary
Secondary
Concomitant
Syncope Other Serious 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Hospitalization 7/31/2009 52 Male 11/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 7/31/2009 52 Male 11/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Hospitalization 7/31/2009 52 Male 11/13/2009 United Kingdom
Primary
Concomitant
Hyponatraemia Hospitalization 7/31/2009 52 Male 11/19/2009
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/24/2008 69 Female 115 lb 12/1/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Interacting
Duodenal Ulcer Haemorrhage Life Threatening 5/24/2008 69 Female 115 lb 12/9/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Duodenal Ulcer Haemorrhage Life Threatening 5/24/2008 69 Female 115 lb 12/9/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
Duodenal Ulcer Haemorrhage Life Threatening 5/24/2008 69 Female 115 lb 12/9/2009 Other Health Professional Germany
Primary
Concomitant
Interacting
White Blood Cell Count Increased Life Threatening 5/24/2008 69 Female 115 lb 12/8/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 47 Male 257 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 69 Female 1/7/2010
Primary
Secondary
Concomitant
Somnolence Other Serious 3/25/2009 29 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/23/2010 Male 2/11/2010 Physician United States
Primary
Concomitant
Sedation 12/23/2008 24 Male 190 lb 1/20/2009 Other Health Professional United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 3/18/2010 46 Male 185 lb 3/19/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/4/2010 77 Female 4/23/2010 Germany
Primary
Concomitant
Muscle Injury Other Serious 68 Female 137 lb 6/14/2010 Physician Canada
Primary
Concomitant
Myoclonic Epilepsy Other Serious 5/26/2009 61 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 47 Male 126 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Other Serious 49 Male 290 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Aspiration Death 6/11/2009 67 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 43 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Leukopenia Other Serious 6/22/2009 52 Male 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 22 Female 195 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 8/3/2009 28 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/15/2009 60 Female 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 85 Female 119 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 9/25/2009 55 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 67 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 9/27/2009 34 Male 240 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 47 Female 148 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Death Death 82 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/10/2009 38 Male 242 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/15/2009 60 Female 6/24/2010 Other Health Professional United States
Primary
Concomitant
Death Death 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Granulocytopenia Other Serious 1/4/2010 60 Female 6/24/2010 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/13/2010 66 Female 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 2/22/2010 53 Male 125 lb 6/24/2010 Pharmacist United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 2/24/2010 39 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 50 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 51 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 3/5/2010 51 Male 240 lb 6/24/2010 Physician United States
Primary
Concomitant
Leukopenia Other Serious 3/18/2010 58 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Death 4/1/2010 48 Male 323 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Surgery Other Serious 12/1/2009 55 Female 159 lb 8/18/2010 Consumer Canada
Primary
Concomitant
Surgery Other Serious 12/1/2009 55 Female 159 lb 8/27/2010 Consumer Canada
Primary
Concomitant
Tremor 4/21/2010 61 Female 175 lb 5/18/2010 Pharmacist United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 1/1/2009 74 Male 9/16/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Fracture Displacement Hospitalization 8/1/2010 52 Male 262 lb 9/24/2010 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/25/2010 67 Female 185 lb 11/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pathological Fracture Hospitalization 8/1/2010 52 Male 262 lb 11/11/2010 Physician United States
Primary
Concomitant
Skin Haemorrhage Other Serious 9/26/2010 48 Female 115 lb 9/27/2010 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 10/7/2008 78 Male 173 lb 12/15/2010 Physician
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 10/7/2008 78 Male 173 lb 12/22/2010 Physician
Primary
Concomitant
Hydrocephalus Other Serious 1/1/2010 47 Male 240 lb 3/18/2011 Consumer United States
Primary
Secondary
Concomitant
Myocarditis Hospitalization 1/18/2011 25 Male 206 lb 3/17/2011 Pharmacist United States
Primary
Concomitant
Cardiolipin Antibody Positive Other Serious 63 Female 3/29/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 63 Female 3/29/2011 Physician United States
Primary
Concomitant
Atelectasis Hospitalization 1/1/2011 25 Male 206 lb 4/1/2011 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 1/1/2009 69 Male 236 lb 4/11/2011 Consumer United States
Primary
Secondary
Concomitant
Skin Irritation Disability 10/1/2009 68 Male 235 lb 4/13/2011 Consumer United States
Primary
Concomitant
Vomiting Disability 10/1/2009 70 Male 235 lb 4/18/2011 Consumer United States
Primary
Secondary
Concomitant
Circulatory Collapse Other Serious 3/30/2011 81 Male 256 lb 5/5/2011 Other Health Professional Netherlands
Primary
Concomitant
Myoclonus Other Serious 6/1/2008 29 Male 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Gastritis Hospitalization 2/28/2011 56 Male 165 lb 6/6/2011 Other Health Professional Ireland
Primary
Concomitant
Haemoptysis Death 3/26/2004 73 Male 6/4/2011 Pharmacist United States
Primary
Concomitant
Constipation Hospitalization 2/22/2011 72 Male 6/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Metastatic Neoplasm Death 12/1/2003 56 Male 6/8/2011 Other Health Professional New Zealand
Primary
Concomitant
Death Death 12/7/2005 66 Female 6/6/2011 Physician New Zealand
Primary
Concomitant
Renal Failure Acute Other Serious 8/18/2005 68 Male 6/4/2011 Pharmacist United Kingdom
Primary
Concomitant
Pneumonia Hospitalization 10/1/2005 68 Male 6/2/2011 Physician United Kingdom
Primary
Concomitant
Hernia Hospitalization Male 6/4/2011 Consumer Ireland
Primary
Concomitant
Circulatory Collapse Other Serious 1/12/2007 43 Male 5/30/2011 Physician United Kingdom
Primary
Concomitant

Drug Data