Ascorbic Acid combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Arthralgia 48 236 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/2/2006 Male 199 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Endophthalmitis Other Serious 4/27/2006 80 Female 6/19/2006 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 8/1/2004 74 Female 114 lb 6/29/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Prothrombin Level Abnormal 65 Female 141 lb 8/1/2006 Consumer United States
Primary
Concomitant
Somnolence 4/24/2006 60 Female 180 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2006 66 Male 252 lb 9/12/2006 United States
Primary
Concomitant
Pain Hospitalization 8/28/2006 52 Male 178 lb 9/19/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/15/2006 66 Male 315 lb 10/4/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 10/9/2006 Physician Canada
Primary
Concomitant
Weight Decreased Hospitalization 5/25/2006 66 Male 252 lb 10/5/2006 Physician United States
Primary
Concomitant
Visual Disturbance 4/27/2006 81 Female 10/27/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 115 lb 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 6/15/2006 66 Male 315 lb 10/23/2006 United States
Primary
Concomitant
Suicide Attempt Hospitalization 9/1/2006 62 Female 183 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Surgery Other Serious Female 12/4/2006 Physician Canada
Primary
Concomitant
Hypersensitivity Other Serious 1/1/1986 Male 212 lb 12/1/2006 Consumer Canada
Primary
Concomitant
Drug Ineffective 7/1/2006 83 Male 9/12/2006 United States
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 10/10/2006 79 Female 141 lb 12/21/2006 United States
Primary
Secondary
Concomitant
Logorrhoea 8/3/2006 70 Male 78 lb 10/11/2006 Consumer United States
Primary
Secondary
Concomitant
Nausea 47 Male 226 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Paranoia 55 Male 1/24/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 6/16/2005 76 Male 386 lb 2/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/6/2006 88 Female 202 lb 1/5/2007 Pharmacist United States
Primary
Concomitant
Occult Blood Positive Hospitalization 9/29/2006 75 Male 216 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased 7/1/2006 66 Male 252 lb 2/15/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 1/25/2007 74 Male 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/9/2006 66 Male 3/10/2007 Physician Canada
Primary
Secondary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Hypoaesthesia 9/15/2005 20 Female 115 lb 1/23/2007 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased 8/1/2005 66 Female 209 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 3/9/2007 68 Male 161 lb 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Cerebral Arteriosclerosis Hospitalization 3/9/2007 Male 161 lb 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Death Death 4/5/2007 75 Male 5/3/2007 United States
Primary
Concomitant
Dysuria Other Serious 1/1/2006 Female 161 lb 5/16/2007 Consumer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 8/1/2002 68 Male 201 lb 5/16/2007 Other Health Professional United States
Primary
Concomitant
Flat Affect Hospitalization 5/4/2006 77 Female 12/13/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 5/18/2007 72 Female 201 lb 5/23/2007 Consumer United States
Primary
Concomitant
Palpitations Other Serious 83 Male 3/19/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/14/2006 75 Male 216 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Tendon Injury Hospitalization 3/12/2007 60 Male 6/19/2007 Consumer United States
Primary
Concomitant
Multiple Myeloma Death 4/5/2007 75 Male 6/11/2007 Physician United States
Primary
Concomitant
Cerebral Arteriosclerosis Hospitalization 3/9/2007 Male 161 lb 7/24/2007 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/1/2005 Male 172 lb 7/25/2007 Australia
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/1/2006 Female 161 lb 7/25/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 8/6/2007 Consumer United States
Primary
Concomitant
Tinnitus 3/1/2007 85 Male 172 lb 7/10/2007 Consumer United States
Primary
Concomitant
Hypocalcaemia Hospitalization 2/15/2007 48 Male 163 lb 8/6/2007 Other Health Professional United States
Primary
Concomitant
Insomnia 3/30/2007 79 Female 210 lb 7/10/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 8/21/2007 69 Female 160 lb 8/29/2007 Pharmacist United States
Primary
Concomitant
Swollen Tongue Hospitalization 9/17/2007 75 Female 10/1/2007 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 8/1/2002 68 Male 201 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Palpitations Other Serious 83 Male 9/12/2007 Physician United States
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 12/1/2005 55 Female 10/8/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 69 Male 10/24/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 72 Female 123 lb 11/1/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/16/2007 United States
Primary
Concomitant
Retinal Exudates Other Serious 9/13/2007 43 Female 97 lb 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/27/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/30/2007 United States
Primary
Concomitant
Retinal Exudates Other Serious 9/1/2007 43 Female 97 lb 11/30/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/7/2007 United States
Primary
Concomitant
Femoral Hernia Hospitalization 12/16/2003 Female 170 lb 12/10/2007 United Kingdom
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/14/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/17/2007 United States
Primary
Concomitant
Myalgia Other Serious 1/1/2005 72 Male 190 lb 12/17/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 12/27/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Male 206 lb 12/28/2007 Physician United States
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 12/12/2007 32 Female 1/2/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection 5/3/2007 71 Female 10/9/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 1/9/2008 United States
Primary
Concomitant
Thrombosis Hospitalization 11/2/2007 Female 190 lb 1/14/2008 Consumer United States
Primary
Secondary
Concomitant
Pruritus 1/1/2004 Male 165 lb 1/15/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 1/31/2008 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
Neuropathy Peripheral Death 1/1/2006 Male 175 lb 2/6/2008 Physician United States
Primary
Concomitant
Death Death 1/1/2007 71 Female 2/11/2008 Consumer United States
Primary
Concomitant
Flatulence 10/28/2007 83 Male 165 lb 10/30/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 2/28/2008 United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 3/6/2008 United States
Primary
Concomitant
Bronchiectasis Hospitalization 3/1/2006 36 Female 130 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oxygen Saturation Abnormal Hospitalization 7/8/2007 Female 313 lb 3/19/2008 Physician United States
Primary
Concomitant
Thirst 2/7/2008 72 Male 300 lb 3/24/2008 Consumer United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 4/23/2008 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 5/1/2007 70 Male 220 lb 4/29/2008 United States
Primary
Secondary
Concomitant
Gingival Bleeding Other Serious 2/14/2008 Female 155 lb 5/14/2008 Consumer United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 5/16/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2003 Female 163 lb 6/3/2008 United States
Primary
Concomitant
Rash 3/31/2008 Female 331 lb 6/12/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/21/2008 77 Male 176 lb 6/13/2008 Consumer United States
Primary
Secondary
Concomitant
Pemphigoid Other Serious Female 6/17/2008 Physician Canada
Primary
Concomitant
Gingival Bleeding Other Serious 2/14/2008 Female 155 lb 6/20/2008 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/1/2007 77 Male 205 lb 6/20/2008 Pharmacist United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 82 Female 236 lb 6/25/2008 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/3/2008 58 Male 108 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 200 lb 7/1/2008 Consumer United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 7/11/2008 Physician United States
Primary
Concomitant
Skin Discolouration Male 159 lb 7/29/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Male 200 lb 7/30/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection 3/1/2008 70 Female 7/7/2008 Consumer United States
Primary
Concomitant
Paraesthesia Hospitalization 4/1/2008 Male 190 lb 8/12/2008 Consumer United States
Primary
Concomitant
Rash Female 145 lb 8/27/2008 Consumer United States
Primary
Secondary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Pruritus Female 8/27/2008 United States
Primary
Concomitant
Thrombosis Hospitalization 11/2/2007 Female 190 lb 8/28/2008 Consumer United States
Primary
Secondary
Concomitant
Melaena Other Serious 8/18/2008 71 Male 8/29/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 7/1/2007 Female 9/5/2008 United States
Primary
Concomitant
Pyrexia Other Serious 10/1/2007 Female 9/17/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Other Serious 8/18/2008 71 Male 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Infarction Other Serious 9/3/2008 51 Male 187 lb 9/25/2008 Physician United States
Primary
Concomitant
Respiratory Tract Haemorrhage Other Serious 8/18/2008 71 Male 10/6/2008 Physician Japan
Primary
Secondary
Concomitant
Pain Hospitalization 8/6/2006 50 Female 226 lb 10/13/2008 Consumer United States
Primary
Concomitant
Stomatitis Other Serious 5/1/2007 28 Female 11/4/2008 Consumer United States
Primary
Secondary
Concomitant
Pruritus 7/31/2008 Male 11/26/2008 United States
Primary
Concomitant
Pain 9/1/2008 Male 11/26/2008 United States
Primary
Concomitant
Muscle Spasms 79 Male 220 lb 12/17/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/15/2008 Male 12/30/2008 Physician Switzerland
Primary
Concomitant
International Normalised Ratio Increased Other Serious 43 Female 143 lb 1/14/2009
Primary
Secondary
International Normalised Ratio Increased Other Serious 43 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/25/2008 40 Female 131 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/31/2008 42 Female 1/9/2009 Pharmacist United States
Primary
Concomitant
Sensory Loss Other Serious 2/2/2009 Female 134 lb 2/12/2009 Consumer United States
Primary
Concomitant
Procedural Pain Hospitalization 11/1/2007 Female 2/5/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 8/6/2006 50 Female 226 lb 2/16/2009 Pharmacist United States
Primary
Concomitant
Productive Cough Other Serious 1/1/2006 78 Female 2/18/2009 Consumer United States
Primary
Secondary
Concomitant
Neck Pain 11/10/2008 Female 2/24/2009 United States
Primary
Concomitant
Tremor Female 2/24/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/8/2008 43 Female 142 lb 3/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 12/15/2007 32 Female 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stress Other Serious 43 Female 144 lb 3/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Loss Other Serious 2/2/2009 Female 134 lb 3/20/2009 Consumer United States
Primary
Concomitant
Heart Injury Hospitalization 1/1/2005 83 Male 175 lb 3/20/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/16/2009 70 Female 100 lb 3/19/2009 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/16/2009 70 Female 100 lb 3/19/2009 United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 2/28/2009 Male 206 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Balance Disorder 11/25/2008 84 Male 3/23/2009 Consumer United States
Primary
Concomitant
Oral Candidiasis Hospitalization 1/5/2009 81 Male 123 lb 3/31/2009 Pharmacist United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 2/13/2008 28 Female 115 lb 4/3/2009 Physician Japan
Primary
Concomitant
Syncope Hospitalization 5/31/2004 Female 95 lb 4/10/2009 Other Health Professional United States
Primary
Concomitant

Drug Data