Ascorbic Acid combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Other Serious 1/1/2005 25 Female 2/22/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 Consumer United States
Primary
Concomitant
Methaemoglobinaemia Life Threatening 6/20/2005 17 Female 117 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/9/2006 Physician United States
Primary
Concomitant
Drug Ineffective 12/1/2005 77 Female 3/12/2006 Consumer United States
Primary
Concomitant
Viral Infection Hospitalization 4/1/2006 75 Female 5/25/2006 Physician United States
Primary
Concomitant
Nausea Other Serious 8/17/2005 33 Female 97 lb 5/31/2006 Japan
Primary
Concomitant
Endophthalmitis Other Serious 4/27/2006 80 Female 6/19/2006 Other Health Professional United States
Primary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 United States
Primary
Concomitant
Tongue Coated 9/1/2004 80 Female 5/19/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 6/1/2005 Male 215 lb 8/8/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious Female 8/25/2006 Consumer United States
Primary
Concomitant
Somnolence 4/24/2006 60 Female 180 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Hepatorenal Failure Death 8/12/2006 4 Male 9/1/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Hepatorenal Failure Death 8/18/2006 4 Male 9/13/2006 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Viral Infection Hospitalization 4/1/2006 75 Female 8/4/2006 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 4/1/2006 75 Female 8/4/2006 Physician United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Feeling Cold 11/22/2004 74 Female 8/22/2006 United States
Primary
Concomitant
Visual Disturbance 4/27/2006 81 Female 10/27/2006 Other Health Professional United States
Primary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 11/2/2006 Physician United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 8/3/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 9/15/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 7/25/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 12/1/2006 Physician United States
Primary
Concomitant
Pain In Extremity 1/1/2006 66 Female 162 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Paranoia 55 Male 1/24/2007 Consumer United States
Primary
Concomitant
Subdural Haematoma Life Threatening 10/18/2006 80 Male 191 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 1/31/2007 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious 1/19/2007 Female 138 lb 1/31/2007 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 9/15/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/27/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/3/2006 65 Male 256 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 71 Female 2/27/2007 United States
Primary
Concomitant
Drug Ineffective 75 Male 3/7/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/9/2006 66 Male 3/10/2007 Physician Canada
Primary
Secondary
Concomitant
Angina Pectoris Other Serious 2/1/2007 73 Female 3/13/2007 Consumer United States
Primary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2002 Female 202 lb 4/4/2007 Physician United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Rectal Prolapse Hospitalization 5/30/2006 79 Female 4/16/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Life Threatening 3/7/2007 59 Female 4/17/2007 Physician United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/1/2007 Physician United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 4/30/2007 63 Female 220 lb 5/16/2007 Consumer United States
Primary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2000 Female 202 lb 6/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Limb Discomfort 77 Female 6/29/2007 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/16/2007 47 Female 168 lb 7/10/2007 Physician United States
Primary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 5/26/2007 83 Female 188 lb 10/1/2007 United States
Primary
Concomitant
Off Label Use 6/30/2007 69 Male 9/6/2007 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 7/25/2006 65 Male 256 lb 10/30/2007 Physician United States
Primary
Concomitant
Haemorrhagic Infarction Hospitalization 5/26/2007 83 Female 188 lb 11/8/2007 United States
Primary
Concomitant
Rash 12/19/2006 Male 11/13/2007 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 1/8/2008 65 Female 223 lb 1/9/2008 Physician United States
Primary
Concomitant
Post Procedural Cellulitis Hospitalization 1/8/2008 65 Female 223 lb 1/21/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 1/31/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 12/31/2007 Male 216 lb 2/8/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 10/19/2007 Male 178 lb 3/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 3/19/2008 66 Female 223 lb 3/20/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/7/2008 Female 3/27/2008 Physician United States
Primary
Concomitant
Oedema Other Serious 60 Male 3/31/2008 Consumer United States
Primary
Secondary
Concomitant
Mouth Haemorrhage Hospitalization 3/19/2008 66 Female 223 lb 3/31/2008 Physician United States
Primary
Concomitant
Renal Cancer Metastatic Hospitalization 5/17/2007 Female 227 lb 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death Female 227 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2007 59 Female 185 lb 4/11/2008 United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 2/22/2008 77 Male 165 lb 4/15/2008 United Kingdom
Primary
Concomitant
Urinary Retention 7/1/2007 Female 4/23/2008 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2007 59 Female 185 lb 5/12/2008 United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 5/16/2008 Physician United States
Primary
Concomitant
Scratch Other Serious 1/1/2004 Female 120 lb 5/16/2008 United States
Primary
Concomitant
Scratch Other Serious 1/1/2004 Female 120 lb 5/23/2008 United States
Primary
Concomitant
Premature Labour Other Serious 10/31/2007 Female 157 lb 6/9/2008 United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2007 59 Female 185 lb 6/18/2008 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 7/8/2008 United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 7/11/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization Female 250 lb 7/17/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/19/1999 Female 150 lb 7/31/2008 Physician United States
Primary
Secondary
Concomitant
Vasodilatation Hospitalization 5/28/2008 Female 250 lb 9/2/2008 United States
Primary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 9/23/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 10/2/2008 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 8/27/2008 Female 10/16/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/16/2008 66 Female 230 lb 10/23/2008 Physician United States
Primary
Concomitant
Phlebitis Hospitalization 10/23/2008 66 Female 230 lb 10/24/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/16/2008 66 Female 230 lb 10/29/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 10/16/2008 66 Female 230 lb 11/3/2008 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 11/12/2008 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 11/24/2008 United States
Primary
Concomitant
Vomiting Hospitalization 10/16/2008 66 Female 230 lb 12/1/2008 Physician United States
Primary
Concomitant
Product Quality Issue 9/14/2008 58 Male 12/19/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 65 Female 12/12/2008 Other Health Professional Australia
Primary
Concomitant
Breast Enlargement Other Serious 6/14/2001 1/8/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 43 Female 143 lb 1/14/2009
Primary
Secondary
International Normalised Ratio Increased Other Serious 1/11/2009 Female 1/20/2009 Pharmacist United States
Primary
Concomitant
Breast Enlargement Other Serious 6/14/2001 1/24/2009 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 43 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2008 Male 153 lb 1/26/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Other Serious 1/1/1991 45 Female 270 lb 2/12/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/8/2008 43 Female 142 lb 3/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Rate Increased 11/22/2004 Female 3/16/2009 Consumer
Primary
Concomitant
Stress Other Serious 43 Female 144 lb 3/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 3/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 4/8/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 6/1/2004 Male 178 lb 4/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2009 Female 4/24/2009 Consumer
Primary
Concomitant
Vision Blurred Male 4/3/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2009 Female 5/6/2009 Consumer
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 5/15/2009 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 5/28/2008 Female 250 lb 5/20/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/28/2008 65 Male 5/24/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 6/1/2004 Male 178 lb 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 4/28/2008 65 Male 6/5/2009 United States
Primary
Concomitant
Vomiting 50 Female 200 lb 6/23/2009 United States
Primary
Concomitant
Swollen Tongue Other Serious 5/1/2009 Female 6/18/2009 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 4/8/2009 176 lb 6/25/2009 Physician United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 12/1/2008 Male 236 lb 7/2/2009 Physician United States
Primary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 68 Male 179 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 76 Male 7/15/2009 Lawyer United States
Primary
Concomitant
Swollen Tongue Other Serious 5/16/2009 32 Female 145 lb 7/16/2009 Consumer United States
Primary
Concomitant
Urticaria 1/29/2009 61 Male 320 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 47 Female 201 lb 7/30/2009 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 74 Female 8/18/2009 United States
Primary
Concomitant
Platelet Production Decreased Other Serious 73 Male 375 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 76 Male 165 lb 8/28/2009 United States
Primary
Concomitant
Supraventricular Tachyarrhythmia Hospitalization 57 Male 8/31/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 9/2/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 57 Male 9/9/2009 United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 57 Male 227 lb 9/18/2009 United States
Primary
Concomitant
Vertigo Hospitalization 74 Female 9/23/2009 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 4/28/2009 61 Female 236 lb 10/2/2009 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 1/1/2009 Female 9/29/2009 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 57 Male 227 lb 10/9/2009 United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2008 Female 170 lb 10/23/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 164 lb 10/20/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 72 Male 10/22/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 76 Male 15 lb 10/22/2009 United States
Primary
Concomitant
Vomiting Other Serious 82 Female 10/26/2009 United States
Primary
Concomitant

Drug Data