Ascorbic Acid combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toe Amputation Hospitalization 9/1/2005 Female 220 lb 1/13/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 12/1/2005 Female 164 lb 1/31/2006 Other Health Professional Canada
Primary
Concomitant
Blood Glucose Increased 11/22/2005 55 Male 220 lb 1/20/2006 Consumer United States
Primary
Concomitant
Weight Decreased 12/27/2005 67 Female 216 lb 1/20/2006 Consumer United States
Primary
Concomitant
Nausea 10/4/2005 70 Female 189 lb 1/20/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/7/2006 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2005 Female 164 lb 4/27/2006 Other Health Professional Canada
Primary
Concomitant
Injection Site Irritation Hospitalization Female 5/2/2006 Consumer United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Hypertrichosis 1/1/2005 71 Male 2/21/2006 United States
Primary
Concomitant
Varicose Vein Operation Hospitalization 1/1/2000 53 Male 351 lb 5/9/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/17/2006 55 Female 190 lb 5/3/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/17/2006 55 Female 190 lb 5/12/2006 Physician United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2003 74 Female 6/5/2006 Consumer United States
Primary
Concomitant
Rash 1/16/2006 59 Male 295 lb 5/1/2006 United States
Primary
Concomitant
Salivary Duct Obstruction Hospitalization 5/15/2006 53 Female 173 lb 6/27/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 6/27/2006 Consumer United States
Primary
Secondary
Concomitant
Injection Site Bruising 8/8/2005 76 Female 200 lb 4/17/2006 Consumer United States
Primary
Concomitant
Weight Decreased 8/2/2005 63 Female 227 lb 4/17/2006 Consumer United States
Primary
Concomitant
Rhinorrhoea 12/28/2005 68 Female 185 lb 4/17/2006 Consumer United States
Primary
Concomitant
Urticaria 2/1/2006 37 Female 206 lb 4/17/2006 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 7/5/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 7/7/2006 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral 4/1/2006 66 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Insomnia 1/1/2006 51 Male 230 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 7/31/2006 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 1/24/2006 Male 8/4/2006 Other Health Professional United States
Primary
Concomitant
Endometrial Cancer Stage Ii Other Serious 5/2/2006 64 Female 8/7/2006 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 7/26/2006 62 Male 290 lb 8/14/2006 Physician United States
Primary
Concomitant
Penile Prosthesis Insertion Other Serious Male 257 lb 8/28/2006 United States
Primary
Concomitant
Weight Decreased Hospitalization 7/10/2006 74 Female 187 lb 9/6/2006 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 9/22/2006 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 1/1/2005 Female 9/26/2006 Consumer United States
Primary
Secondary
Concomitant
Arthropathy Other Serious Female 149 lb 10/9/2006 Consumer Canada
Primary
Concomitant
Vomiting Life Threatening 6/8/2006 Female 11/13/2006 Physician United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 11/2/2006 Physician United States
Primary
Concomitant
Pruritus 7/22/2005 50 Female 244 lb 11/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 87 Male 12/8/2006 Consumer United States
Primary
Concomitant
Pubic Rami Fracture Other Serious 8/1/2006 66 Male 206 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/26/2006 71 Female 150 lb 2/12/2007 Consumer United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Medication Error Other Serious 9/14/2006 4/16/2007 Other Health Professional United States
Primary
Concomitant
Wrong Drug Administered Other Serious 1/1/2006 70 Female 4/23/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/13/2007 79 Female 106 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Furuncle 11/1/2006 60 Female 208 lb 8/16/2007 Physician United States
Primary
Concomitant
Musculoskeletal Pain 57 Female 198 lb 9/20/2007 Consumer United States
Primary
Concomitant
Fluid Retention Other Serious 10/1/2007 Female 255 lb 10/23/2007 United States
Primary
Concomitant
Throat Tightness Hospitalization 10/13/2007 65 Female 11/8/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Death 9/19/2007 55 Male 240 lb 12/5/2007 Consumer United States
Primary
Secondary
Concomitant
Localised Infection Other Serious 10/3/2006 Male 157 lb 1/21/2008 United Kingdom
Primary
Concomitant
Throat Tightness Hospitalization 9/1/2007 65 Female 165 lb 1/28/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 10/22/2007 75 Female 3/25/2008 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/7/2008 Female 3/27/2008 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 2/1/2008 30 Female 284 lb 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Gingival Bleeding Other Serious 2/14/2008 Female 155 lb 6/20/2008 Physician United States
Primary
Concomitant
Oedema Other Serious 1/1/2008 Female 135 lb 7/15/2008 Consumer United States
Primary
Secondary
Concomitant
Anosmia Disability 1/1/2006 82 Female 117 lb 8/5/2008 Physician Canada
Primary
Concomitant
Sensation Of Heaviness Life Threatening 3/11/2008 65 Female 209 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 6/2/2008 60 Female 8/11/2008 United States
Primary
Concomitant
Failure To Thrive Disability 5/1/2007 Female 8/21/2008 Physician United States
Primary
Concomitant
Procedural Pain Hospitalization 7/1/2008 Female 8/20/2008 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 63 Female 297 lb 8/22/2008 United States
Primary
Concomitant
Hepatitis Hospitalization 2/1/2008 30 Female 284 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/21/2008 74 Male 185 lb 10/9/2008 Physician Italy
Primary
Concomitant
Urticaria Other Serious 8/17/2008 Female 197 lb 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 12/26/2008 57 Male 300 lb 12/31/2008 Consumer United States
Primary
Concomitant
Pain 6/21/2008 64 Female 2/4/2009 Consumer United States
Primary
Concomitant
Urticaria Other Serious 1/1/2008 Female 220 lb 2/16/2009 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 12/1/2008 Male 2/24/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 12/3/2008 71 Male 227 lb 2/18/2009 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 1/1/2008 Female 220 lb 2/25/2009 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 7/14/2008 57 Female 220 lb 2/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 3/5/2009 Physician United States
Primary
Concomitant
Urticaria Other Serious 8/17/2008 Female 197 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Hospitalization 8/6/2006 50 Female 226 lb 6/10/2009 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 4/22/2002 Female 169 lb 6/24/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 5/1/2008 Female 187 lb 6/22/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 58 Male 284 lb 7/22/2009 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 7/31/2009 United States
Primary
Secondary
Concomitant
Humerus Fracture Disability 6/7/2009 Female 153 lb 7/31/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Other Serious 9/1/2008 Female 220 lb 7/31/2009 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 12/26/2008 57 Male 300 lb 4/9/2009 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Death 64 Male 217 lb 7/22/2009 United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2008 Male 242 lb 8/19/2009 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 6/23/2009 78 Male 172 lb 8/20/2009 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased 7/15/2008 Male 8/21/2009 United States
Primary
Concomitant
Pruritus Male 8/21/2009 United States
Primary
Concomitant
Urticaria 8/17/2008 Female 197 lb 8/21/2009 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Male 170 lb 8/21/2009 United States
Primary
Concomitant
Flushing 9/1/2008 Male 250 lb 8/21/2009 Consumer United States
Primary
Concomitant
Malaise 1/1/2006 74 Female 167 lb 10/2/2009 Consumer United States
Primary
Secondary
Concomitant
Insomnia 1/1/2008 Male 10/2/2009 Consumer
Primary
Concomitant
Pruritus 7/9/2009 Male 200 lb 11/25/2009 United States
Primary
Concomitant
Flushing Male 214 lb 11/25/2009 United States
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 2/1/2010 68 Female 214 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Femur Fracture Hospitalization 12/6/2009 63 Female 205 lb 4/20/2010 United States
Primary
Secondary
Concomitant
Anosmia Disability 1/1/2006 82 Female 117 lb 6/2/2010 Physician Canada
Primary
Concomitant
Pulse Absent Required Intervention 4/26/2010 47 Male 187 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Pruritus 6/1/2010 79 Male 150 lb 8/16/2010 Consumer United States
Primary
Concomitant
Urinary Casts Other Serious 8/3/2010 73 Female 124 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Flushing 1/1/2004 52 Male 290 lb 8/27/2010 United States
Primary
Concomitant
Flushing 8/1/2009 75 Male 177 lb 8/27/2010 United States
Primary
Concomitant
Flushing 8/8/2009 56 Male 220 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 10/12/2009 Female 8/28/2010 United States
Primary
Concomitant
Flushing 11/1/2009 36 Male 277 lb 8/28/2010 United States
Primary
Concomitant
Blood Glucose Increased Male 216 lb 8/28/2010 United States
Primary
Concomitant
Flushing 12/28/2009 Male 8/28/2010 United States
Primary
Concomitant
Heart Rate Increased 2/1/2010 63 Male 8/28/2010 United States
Primary
Concomitant
Flushing Male 203 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 165 lb 8/28/2010 United States
Primary
Concomitant
Skin Burning Sensation Male 249 lb 8/28/2010 United States
Primary
Concomitant
Flushing 9/1/2008 60 Male 240 lb 8/28/2010 United States
Primary
Concomitant
Flushing Female 220 lb 8/28/2010 United States
Primary
Concomitant
Flushing 4/1/2010 69 Male 8/29/2010 United States
Primary
Concomitant
Blood Glucose Increased 4/1/2010 73 Male 245 lb 8/29/2010 United States
Primary
Concomitant
Headache 5/12/2010 56 Female 205 lb 8/29/2010 United States
Primary
Concomitant
Abdominal Pain Upper 6/29/2010 63 Male 210 lb 8/29/2010 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 5/20/2006 67 Female 146 lb 9/1/2010 Consumer Brazil
Primary
Concomitant
Psoriasis Other Serious 4/1/2009 66 Female 196 lb 9/1/2010 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/2001 67 Female 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles 1/1/1998 37 Female 9/20/2010 United States
Primary
Concomitant
Haemorrhage Other Serious 1/1/2010 50 Male 208 lb 9/29/2010 Consumer United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization Male 240 lb 10/5/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/25/2010 10/8/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/8/2010 United States
Primary
Concomitant
Extrasystoles Other Serious 6/3/2010 77 Male 10/22/2010 Physician United States
Primary
Concomitant
Coronary Artery Disease Life Threatening 8/30/2010 67 Male 10/22/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/28/2005 44 Male 437 lb 10/26/2010 United States
Primary
Concomitant
Urinary Tract Infection 73 Female 10/13/2010 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 70 Female 194 lb 11/2/2010 United States
Primary
Concomitant
Enuresis Other Serious 4/1/2008 47 Female 200 lb 11/8/2010 Consumer United States
Primary
Concomitant
Irritable Bowel Syndrome Other Serious 1/1/2006 58 Male 11/11/2010 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 8/30/2010 67 Male 11/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased 7/15/2010 63 Male 249 lb 11/17/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/24/2010 66 Female 11/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Pruritic 1/1/2008 65 Male 154 lb 11/30/2010 Consumer United States
Primary
Secondary
Concomitant
Ageusia 9/3/2010 69 Male 240 lb 11/3/2010 United States
Primary
Concomitant
Death Death 11/16/2010 65 Female 10/24/2010 Other Health Professional United States
Primary
Concomitant
Osteoporosis Other Serious 5/20/2006 67 Female 146 lb 12/16/2010 Consumer Brazil
Primary
Concomitant
Prostatomegaly Other Serious 1/1/2010 73 Male 244 lb 12/3/2010 United States
Primary
Secondary
Concomitant
Psoriasis 2/24/2010 12/19/2010 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2009 70 Female 194 lb 12/22/2010 Physician United States
Primary
Concomitant
Insomnia 12/23/2010 66 Male 170 lb 12/30/2010 Consumer United States
Primary
Concomitant
Erythema 67 Male 1/7/2011 Consumer United States
Primary
Concomitant
Jaundice Hospitalization 11/29/2010 71 Female 1/6/2011 Other Health Professional
Primary
Secondary
Concomitant
Osteoma Hospitalization 12/6/2009 63 Female 205 lb 1/4/2011 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/3/2007 32 Female 135 lb 11/4/2010 Lawyer United States
Primary
Concomitant

Drug Data