Aripiprazole combined with Valproate Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Required Intervention 35 Female 174 lb 12/28/2005 Consumer United States
Primary
Concomitant
Leukopenia Required Intervention 42 Male 2/8/2006 United States
Primary
Concomitant
Unevaluable Event Death 8/10/2005 49 Male 12/14/2005 Pharmacist United States
Primary
Concomitant
Depression Hospitalization 8/3/2005 Female 4/21/2006 Other Health Professional United States
Primary
Secondary
Unevaluable Event Hospitalization 3/31/2006 Male 4/26/2006 Other Health Professional France
Primary
Secondary
Unevaluable Event Hospitalization 3/31/2006 Male 5/5/2006 Other Health Professional France
Primary
Secondary
Suicidal Ideation Hospitalization 4/26/2006 Female 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 1/10/2006 49 Male 230 lb 3/27/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 12/28/2005 21 Male 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 1/16/2006 29 Male 170 lb 4/5/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/17/2005 20 Female 1/27/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/4/2005 17 Male 6/20/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/11/2005 46 Female 2/7/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/27/2005 20 Male 6/1/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/10/2006 31 Male 300 lb 5/17/2006 United States
Primary
Concomitant
Granulocytopenia Required Intervention 8/25/2005 25 Male 5/31/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/9/2005 35 Male 1/17/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 9/19/2005 39 Female 1/16/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 4/26/2006 Female 8/3/2006 Other Health Professional France
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 3/31/2006 Male 8/3/2006 Other Health Professional France
Primary
Secondary
Drug Withdrawal Syndrome Hospitalization 7/30/2006 24 Female 8/21/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Psychiatric Symptom Hospitalization 8/3/2006 41 Female 8/22/2006 Physician Japan
Primary
Concomitant
Granulocytopenia Required Intervention 8/29/2005 14 Male 1/11/2006 Consumer United States
Primary
Concomitant
Granulocytopenia Required Intervention 3/7/2006 52 Male 4/18/2006 Consumer United States
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 9/12/2006 Other Health Professional Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 9/19/2006 Other Health Professional Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/24/2006 30 Female 10/6/2006 Other Health Professional Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 10/19/2006 44 Female 1/4/2007 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal 5/1/2006 51 Male 12/29/2006 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome 10/3/2006 22 Male 2/6/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Major Depression Hospitalization 1/14/2007 41 Female 165 lb 2/21/2007 Other Health Professional South Africa
Primary
Secondary
Concomitant
Hepatitis Fulminant Other Serious 10/19/2006 44 Female 3/15/2007 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 4/16/2007 44 Male 227 lb 5/12/2007 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 7/23/2007 47 Female 8/2/2007 Other Health Professional Japan
Primary
Secondary
Electroencephalogram Abnormal Hospitalization 1/24/2007 11 Female 8/10/2007 Physician Japan
Primary
Concomitant
Electroencephalogram Abnormal Other Serious 1/24/2007 11 Female 8/22/2007 Physician Japan
Primary
Concomitant
Cardio-respiratory Arrest Life Threatening 7/23/2007 47 Female 9/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Electroencephalogram Abnormal Other Serious 1/24/2007 11 Female 9/6/2007 Physician Japan
Primary
Concomitant
Poriomania Other Serious 4/20/2007 34 Female 12/21/2007 Other Health Professional Japan
Primary
Concomitant
Poriomania Other Serious 4/20/2007 34 Female 1/14/2008 Other Health Professional Japan
Primary
Concomitant
Restlessness Hospitalization 12/28/2007 21 Male 1/23/2008 Other Health Professional Japan
Primary
Concomitant
Weight Increased Other Serious 11/1/2007 35 Male 1/29/2008 Physician Australia
Primary
Concomitant
Hyponatraemia Other Serious 8/1/2005 69 Male 3/4/2008 Other Health Professional India
Primary
Concomitant
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
Mania 2/1/2008 Male 6/12/2008 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2006 22 Male 6/19/2008 Physician France
Primary
Secondary
Urticaria 8/30/2007 Female 250 lb 8/27/2008 Consumer United States
Primary
Concomitant
Weight Decreased 5/15/2008 Female 250 lb 8/29/2008 United States
Primary
Concomitant
Stomach Discomfort 6/1/2008 Male 248 lb 8/29/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2007 22 Male 9/24/2008 Consumer United States
Primary
Concomitant
Muscular Weakness Disability 10/1/2008 43 Female 11/24/2008 Other Health Professional United Kingdom
Primary
Concomitant
Flushing Female 11/26/2008 United States
Primary
Concomitant
Acute Hepatic Failure Life Threatening 9/29/2008 8 Male 55 lb 12/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain 10/1/2008 Male 321 lb 12/12/2008 Physician United States
Primary
Concomitant
Confusional State Other Serious 63 Female 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 28 Male 1/27/2009 Other Health Professional United States
Primary
Secondary
Troponin Increased Other Serious 28 Male 2 lb 1/23/2009 Physician United States
Primary
Secondary
Vomiting Other Serious 7/7/2008 Male 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Disorder Other Serious 28 Male 2/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 28 Male 2/6/2009 France
Primary
Secondary
Tremor Female 3/4/2009 Consumer United States
Primary
Concomitant
Insomnia Male 141 lb 3/12/2009 Consumer United States
Primary
Secondary
Concomitant
Left Ventricular Hypertrophy Other Serious 25 Male 3/21/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 28 Male 3/23/2009 United States
Primary
Concomitant
Tachypnoea Other Serious 28 Male 3/26/2009 France
Primary
Secondary
Pulmonary Oedema Other Serious 28 Male 3/27/2009 United Kingdom
Primary
Secondary
Drug Interaction Hospitalization 1/13/2009 Female 5/26/2009 Physician Germany
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/15/2009 14 Male 7/31/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Somnolence Other Serious 3/1/2007 42 Male 8/3/2009 Physician India
Primary
Secondary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 9/9/2009 Physician France
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 10/1/2008 Male 321 lb 9/12/2009 Physician United States
Primary
Concomitant
Myopia Other Serious 21 Female 10/13/2009 Other Health Professional Turkey
Primary
Concomitant
Somnolence Other Serious 3/1/2007 42 Male 11/5/2009 Physician India
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 11/17/2009 Physician United Kingdom
Primary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 194 lb 11/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Mania Hospitalization 19 Female 11/24/2009 Other Health Professional Turkey
Primary
Concomitant
Mania Hospitalization 19 Female 11/26/2009 Other Health Professional Turkey
Primary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 194 lb 12/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 1/13/2010 Physician France
Primary
Secondary
Concomitant
Convulsion Hospitalization 2/14/2009 49 Female 1/21/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 3/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/29/2009 Male 3/15/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Hospitalization Male 4/12/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Hospitalization Male 4/14/2010 Pharmacist United Kingdom
Primary
Concomitant
Weight Increased Hospitalization Male 4/29/2010 Pharmacist United Kingdom
Primary
Concomitant
Metabolic Syndrome Other Serious 10/1/2008 40 Male 5/24/2010 France
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 4/13/2010 63 Male 5/28/2010 Physician United Kingdom
Primary
Concomitant
Tachycardia Other Serious 5/25/2010 27 Male 7/13/2010 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Increased Life Threatening 3/5/2010 38 Female 8/6/2010 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 28 Male 198 lb 9/9/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2003 12 Female 9/17/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 29 Male 198 lb 9/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 8/22/2010 47 Female 11/29/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Overdose Other Serious 8/22/2010 47 Female 12/13/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 4/14/2010 25 Male 12/16/2010 Other Health Professional Australia
Primary
Concomitant
Arrhythmia Life Threatening 11/25/2010 32 Male 1/10/2011 Physician United Kingdom
Primary
Concomitant
Malaise Hospitalization 11/25/2010 32 Male 1/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Hypertrophy Hospitalization 11/25/2010 32 Male 1/18/2011 Physician United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 11/25/2010 32 Male 1/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Prolactin Increased Other Serious 32 Female 1/28/2011 Physician Japan
Primary
Concomitant
Dyslalia Other Serious 11/5/2009 32 Female 2/16/2011 Physician Japan
Primary
Concomitant
Schizophrenia Other Serious 8/22/2010 47 Female 2/7/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Sedation Other Serious Male 3/15/2011 United Kingdom
Primary
Concomitant
Physical Assault Other Serious 12/1/2010 26 Male 3/17/2011 Physician New Zealand
Primary
Concomitant
Tachycardia Other Serious 5/25/2010 27 Male 4/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Drop Attacks Other Serious 6/1/2008 28 Male 198 lb 5/13/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Male 5/20/2011 Physician United Kingdom
Primary
Concomitant
Drop Attacks Death 6/1/2008 28 Male 198 lb 5/20/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 4/28/2011 47 Female 261 lb 6/2/2011 Other Health Professional United Kingdom
Primary
Concomitant
Schizophrenia Death 6/1/2008 28 Male 198 lb 6/3/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 6/1/2008 28 Male 198 lb 6/3/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 10/1/2005 37 Female 6/14/2011 Physician Australia
Primary
Concomitant
Fractured Sacrum Other Serious 7/11/2005 55 Male 6/14/2011 Physician United Kingdom
Primary
Concomitant
Bipolar Ii Disorder Hospitalization 63 Female 6/16/2011 Other Health Professional Japan
Primary
Concomitant
Neutropenia Other Serious 4/15/2011 28 Male 7/5/2011 Pharmacist
Primary
Concomitant
Pyrexia Other Serious 9/14/2010 69 Male 143 lb 7/25/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/15/2011 28 Male 7/22/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dilatation Ventricular Hospitalization 1/1/2009 20 Female 8/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2009 20 Female 8/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Salivary Hypersecretion Other Serious 7/21/2011 23 Male 190 lb 8/22/2011 Physician United Kingdom
Primary
Concomitant
Sinus Tachycardia Hospitalization 1/1/2009 20 Female 9/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 1/1/2009 20 Female 9/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Delirium Hospitalization Male 9/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 6/20/2011 71 Male 10/1/2011 Pharmacist United States
Primary
Concomitant
Monocyte Count Increased Other Serious 9/10/2010 45 Female 10/5/2011 Physician Japan
Primary
Concomitant
Delirium Other Serious Male 10/5/2011 Other Health Professional Japan
Primary
Secondary
Neutrophil Count Decreased Other Serious 9/2/2011 25 Female 10/7/2011 Physician Ireland
Primary
Concomitant
Neutrophil Count Decreased Other Serious 9/2/2011 25 Female 10/17/2011 Other Health Professional Ireland
Primary
Concomitant
Lymphocyte Count Increased Disability 5/12/2011 45 Male 10/17/2011 Physician United Kingdom
Primary
Concomitant
Akathisia Other Serious Male 10/17/2011 Other Health Professional Japan
Primary
Secondary
Hyponatraemia Hospitalization 56 Female 10/24/2011 Other Health Professional Australia
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/15/2011 28 Male 10/24/2011 Pharmacist
Primary
Secondary
Concomitant
Local Swelling Other Serious 7/21/2011 23 Male 203 lb 11/8/2011 Physician United Kingdom
Primary
Concomitant
Anogenital Warts Other Serious 9/2/2011 25 Female 11/21/2011 Other Health Professional Ireland
Primary
Concomitant
Chronic Lymphocytic Leukaemia Disability 5/12/2011 45 Male 11/28/2011 Physician United Kingdom
Primary
Concomitant
Psychotic Disorder Hospitalization 5/6/2010 19 Male 11/30/2011 Other Health Professional South Africa
Primary
Secondary
Concomitant
Dysphagia Hospitalization 10/15/2011 50 Female 201 lb 12/5/2011 Other Health Professional Ireland
Primary
Concomitant
Catatonia Hospitalization 61 Female 12/23/2011 Other Health Professional Australia
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 61 Female 12/23/2011 Other Health Professional Australia
Primary
Concomitant
Antipsychotic Drug Level Below Therapeutic Other Serious Male 12/27/2011 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious Female 12/29/2011 Physician United Kingdom
Primary
Concomitant
Salivary Gland Pain Other Serious 8/31/2011 25 Female 12/29/2011 Physician Ireland
Primary
Concomitant
Confusional State Other Serious Female 1/4/2012 Physician United Kingdom
Primary
Concomitant
Pharyngitis Other Serious 10/12/2011 37 Male 238 lb 1/6/2012 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 8/1/2010 56 Male 198 lb 1/12/2012 Pharmacist Ireland
Primary
Concomitant
Drug Interaction Other Serious 8/1/2010 56 Male 198 lb 1/17/2012 Physician Ireland
Primary
Secondary
Concomitant
Epididymal Infection Disability 8/1/2010 56 Male 198 lb 1/17/2012 Physician Ireland
Primary
Secondary
Concomitant
Salivary Gland Pain Other Serious 8/31/2011 25 Female 1/17/2012 Physician Ireland
Primary
Concomitant
Catatonia Hospitalization 61 Female 1/18/2012 Other Health Professional Australia
Primary
Concomitant

Drug Data