Arimidex combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Optic Neuritis Retrobulbar Other Serious 10/1/2005 39 Female 165 lb 2/3/2006 Physician France
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Papillary Muscle Rupture Hospitalization 1/17/2006 48 Female 154 lb 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 2/24/2006 Female 3/24/2006 Physician Japan
Primary
Concomitant
Optic Neuritis Retrobulbar Other Serious 10/1/2005 39 Female 165 lb 3/29/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 2/24/2006 59 Female 4/10/2006 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 4/10/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 1/1/2006 58 Female 143 lb 4/14/2006 Other Health Professional Spain
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 4/26/2006 Physician Germany
Primary
Secondary
Concomitant
Death Death 4/2/2006 82 Female 5/4/2006 Physician Japan
Primary
Secondary
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Vital Capacity Abnormal Disability 2/21/2006 Female 5/22/2006 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 6/20/2006 United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 6/14/2006 Physician Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 6/9/2006 59 Female 134 lb 7/17/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Ventricular Fibrillation Life Threatening 6/9/2006 59 Female 134 lb 7/26/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Cardio-respiratory Arrest Death 4/1/2006 83 Female 132 lb 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 4/1/2006 83 Female 132 lb 8/9/2006 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2004 58 Female 173 lb 10/13/2006 Physician United Kingdom
Primary
Concomitant
Thrombocytopenic Purpura Hospitalization 6/26/2006 58 Female 150 lb 10/24/2006 Other Health Professional France
Primary
Concomitant
Osteonecrosis Hospitalization 2/28/2005 58 Female 173 lb 10/25/2006 Physician United Kingdom
Primary
Concomitant
Tendon Rupture Hospitalization 1/17/2006 48 Female 154 lb 10/25/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/1/2004 56 Female 150 lb 12/4/2006 Other Health Professional France
Primary
Concomitant
Tachycardia Hospitalization 1/17/2006 48 Female 154 lb 11/22/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2006 58 Female 143 lb 1/18/2007 Other Health Professional Spain
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Uterine Cancer Other Serious 1/4/2006 57 Female 2/22/2007 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2007 50 Female 4/11/2007 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 54 Female 4/21/2007 Physician Brazil
Primary
Concomitant
Osteonecrosis Hospitalization 12/1/2004 58 Female 173 lb 6/2/2007 Physician United Kingdom
Primary
Concomitant
Polyarthritis Other Serious 36 Female 7/6/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Polyarthritis Other Serious 61 Female 7/9/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Toothache Other Serious 5/1/2006 65 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 7/1/2007 68 Female 104 lb 9/28/2007 Physician Japan
Primary
Concomitant
Urticaria Female 10/1/2007 United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 10/15/2007 Female 123 lb 12/28/2007 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 12/19/2007 Female 185 lb 1/24/2008 Consumer United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 51 Female 2/5/2008 Physician United Kingdom
Primary
Secondary
Osteonecrosis Other Serious 51 Female 3/6/2008 Other Health Professional United Kingdom
Primary
Interacting
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/17/2008 Physician Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/18/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 3/18/2008 Other Health Professional United Kingdom
Primary
Interacting
Weight Decreased Other Serious 51 Female 3/21/2008 Other Health Professional United Kingdom
Primary
Interacting
Weight Decreased Other Serious 51 Female 4/4/2008 Other Health Professional United Kingdom
Primary
Interacting
Pathological Fracture Other Serious 12/21/2007 58 Female 172 lb 4/8/2008 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 51 Female 4/14/2008 Other Health Professional United Kingdom
Primary
Interacting
Pathological Fracture Other Serious 12/21/2007 58 Female 172 lb 4/18/2008 Physician Germany
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 9/15/2007 62 Female 101 lb 5/7/2008 Other Health Professional Australia
Primary
Secondary
Swelling Other Serious 6/9/2007 Female 126 lb 5/20/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/29/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Tooth Deposit Other Serious 12/1/2005 Female 132 lb 6/5/2008 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 6/9/2007 Female 126 lb 7/31/2008 Physician Denmark
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 8/22/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2008 Female 9/17/2008 Physician Germany
Primary
Secondary
Tooth Deposit Other Serious 12/1/2005 Female 132 lb 9/17/2008 Physician United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 4/8/2008 50 Female 10/10/2008 Physician France
Primary
Secondary
Rash Hospitalization 11/29/2008 Female 1/6/2009 Consumer United Kingdom
Primary
Concomitant
Rash Hospitalization 11/29/2008 Female 1/26/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 3/1/2008 49 Female 4/1/2009 Physician France
Primary
Secondary
Tooth Extraction Other Serious 9/17/2008 Female 132 lb 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 11/29/2008 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Teeth Brittle Other Serious 3/7/2009 47 Female 331 lb 6/23/2009 Other Health Professional Germany
Primary
Concomitant
Ovarian Cancer Death 5/22/2009 67 Female 6/29/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Tooth Extraction Other Serious 11/1/2007 76 Female 7/10/2009 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Hospitalization 12/21/2004 Female 173 lb 8/6/2009 Physician United Kingdom
Primary
Concomitant
Mucosal Inflammation Other Serious 2/2/2009 62 Female 8/18/2009 Physician France
Primary
Secondary
Abortion Spontaneous Other Serious 36 Female 9/15/2009 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 51 Female 10/1/2009 Other Health Professional United Kingdom
Primary
Interacting
General Physical Health Deterioration Hospitalization 6/15/2007 Female 131 lb 10/8/2009 Physician Germany
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 7/22/2009 10/9/2009 Physician United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 6/15/2007 Female 131 lb 10/27/2009 Physician Germany
Primary
Concomitant
Ejection Fraction Decreased Other Serious 4/9/2009 60 Female 193 lb 9/29/2009 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/2/2008 Female 12/21/2009 Physician United States
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 6/29/2007 Female 126 lb 1/4/2010 Denmark
Primary
Secondary
Concomitant
Peptostreptococcus Infection Other Serious 9/1/2009 Female 2/8/2010 Other Health Professional Denmark
Primary
Concomitant
Acute Myeloid Leukaemia Other Serious 4/11/2007 Female 206 lb 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/2/2008 Female 2/24/2010 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 6/2/2008 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 4/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 5/4/2010 United States
Primary
Concomitant
Lymphoedema Hospitalization 11/22/2009 69 Female 151 lb 5/11/2010 Physician Ireland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 6/11/2010 United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 6/9/2010 57 Female 7/12/2010 Physician France
Primary
Secondary
Alopecia Other Serious 4/1/2006 61 Female 7/15/2010 Physician France
Primary
Secondary
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 8/29/2010 United States
Primary
Concomitant
Death Other Serious 3/28/2010 81 Female 163 lb 11/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Bone Disorder Other Serious 1/1/2010 63 Female 1/10/2011 Pharmacist Canada
Primary
Secondary
Concomitant
Death Death 1/24/2009 68 Female 126 lb 2/4/2011 Denmark
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 9/1/2009 47 Female 2/10/2011 Other Health Professional Denmark
Primary
Concomitant
Bone Disorder Other Serious 1/1/2010 63 Female 2/17/2011 Physician Canada
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 2/18/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Abscess Death 1/24/2009 68 Female 126 lb 2/25/2011 Physician Denmark
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 1/1/2001 44 Female 134 lb 6/6/2011 Other Health Professional United States
Primary
Concomitant
Osteomyelitis Other Serious Female 132 lb 7/25/2011 Physician Japan
Primary
Concomitant
Swelling Hospitalization 4/1/2011 72 Female 132 lb 8/16/2011 Physician Japan
Primary
Concomitant
Bone Density Decreased Other Serious 9/17/2009 62 Female 8/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 4/1/2011 72 Female 132 lb 9/4/2011 Physician Japan
Primary
Concomitant
Arthralgia Hospitalization 9/17/2009 62 Female 9/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 5/1/2009 71 Female 157 lb 9/9/2011 Lawyer United States
Primary
Concomitant
Anal Fissure Other Serious 5/1/2009 71 Female 157 lb 9/9/2011 Lawyer United States
Primary
Concomitant
Actinic Keratosis Other Serious 11/1/2005 56 Female 123 lb 9/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 9/1/2009 72 Female 10/17/2011 Physician Japan
Primary
Secondary
Oedema Peripheral Other Serious 11/1/2005 56 Female 123 lb 10/28/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious Female 11/17/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Cirrhosis Death 43 Female 11/20/2011 Other Health Professional Israel
Primary
Secondary
Hepatic Failure Death 51 Female 11/18/2011 Israel
Primary
Secondary
Concomitant
Cardiac Cirrhosis Death 43 Female 11/18/2011 Israel
Primary
Secondary
Concomitant
Liver Scan Abnormal Death 43 Female 12/1/2011 Other Health Professional Israel
Primary
Secondary
Acute Myeloid Leukaemia Death 9/1/2009 72 Female 12/5/2011 Physician Japan
Primary
Secondary
Hypoaesthesia Other Serious 11/30/2011 46 Female 2/3/2012 Physician United Kingdom
Primary
Concomitant
Alopecia Disability Female 2/21/2012 Physician France
Primary
Secondary
Cardiac Failure Hospitalization 11/1/2010 60 Female 2/29/2012 Other Health Professional France
Primary
Secondary
Pulmonary Hypertension Hospitalization 11/1/2010 59 Female 3/5/2012 Physician France
Primary
Secondary
Alopecia Disability Female 3/23/2012 Physician France
Primary
Secondary
Alopecia Other Serious 3/1/2012 67 Female 3/28/2012 Consumer Australia
Primary
Concomitant
Alopecia Disability 5/29/2008 59 Female 4/10/2012 Physician France
Primary
Secondary
Pyrexia Hospitalization 1/8/2010 62 Female 4/25/2012 Physician France
Primary
Concomitant
Escherichia Bacteraemia Other Serious 8/1/2002 59 Female 200 lb 5/4/2012 Physician United States
Primary
Secondary
Concomitant
Alopecia Other Serious 3/1/2012 67 Female 5/7/2012 Physician Australia
Primary
Concomitant
Oral Candidiasis Hospitalization 8/1/2002 59 Female 200 lb 5/15/2012 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 8/1/2002 59 Female 200 lb 5/30/2012 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 8/1/2002 59 Female 200 lb 6/6/2012 Lawyer United States
Primary
Secondary
Concomitant
Hypocalcaemia Other Serious 8/1/2002 59 Female 200 lb 6/7/2012 Lawyer United States
Primary
Secondary
Concomitant
Metastases To Pleura Other Serious 5/1/2007 71 Female 6/28/2012 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Other Serious 7/1/2011 75 Female 6/28/2012 Other Health Professional France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 6/6/2011 75 Female 6/29/2012 Physician France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Other Serious 1/1/2009 72 Female 7/2/2012 Other Health Professional France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Other Serious Female 7/2/2012 Other Health Professional France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/1/2011 75 Female 7/3/2012 Physician France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Other Serious 7/1/2011 75 Female 7/5/2012 Physician France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 1/1/2009 72 Female 7/9/2012 Other Health Professional France
Primary
Secondary
Concomitant
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/1/2011 75 Female 7/10/2012 Consumer France
Primary
Secondary
Tongue Neoplasm Malignant Stage Unspecified Hospitalization 7/1/2011 75 Female 7/10/2012 Other Health Professional France
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 7/1/2011 75 Female 7/11/2012 Physician France
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 8/1/2002 59 Female 200 lb 7/24/2012 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 11/1/2010 60 Female 7/25/2012 Other Health Professional France
Primary
Secondary
Bone Lesion Other Serious 3/1/2012 77 Female 7/27/2012 Other Health Professional France
Primary
Concomitant
Acute Promyelocytic Leukaemia Hospitalization 11/1/2011 51 Female 108 lb 8/15/2012 Physician Japan
Primary
Concomitant
Hepatomegaly Hospitalization 8/1/2002 59 Female 200 lb 8/21/2012 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 11/2010 60 Female 9/27/2012 Other Health Professional Fr
Primary
Secondary
Pancytopenia Hospitalization 11/2011 51 Female 108 lb 9/10/2012 Physician Jp
Primary
Concomitant
Disease Progression Other Serious 9/4/2012 Physician Country Not Specified
Primary
Concomitant
Disease Progression Other Serious 9/4/2012 Physician Country Not Specified
Primary
Concomitant
Disease Progression Other Serious 9/4/2012 Physician Country Not Specified
Primary
Concomitant
Disease Progression Other Serious 9/4/2012 Physician Country Not Specified
Primary
Concomitant
Wound Death 8/2002 Female 200 lb 10/16/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data