Aricept combined with Zyprexa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Yellow Skin Death 1/1/2004 85 Female 12/24/2005 United States
Primary
Concomitant
Rash 11/2/2005 77 Female 165 lb 2/28/2006 Consumer United States
Primary
Concomitant
Bradycardia Hospitalization 7/1/2005 Male 8/24/2005 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 9/12/2005 75 Female 132 lb 2/22/2006 Physician Denmark
Primary
Concomitant
Sudden Death Death 9/12/2005 75 Female 132 lb 3/4/2006 Physician Denmark
Primary
Concomitant
Renal Failure Hospitalization 3/1/2006 Female 115 lb 3/23/2006 Consumer United States
Primary
Concomitant
Weight Fluctuation Other Serious 5/1/2002 93 Female 3/29/2006 United States
Primary
Secondary
Concomitant
Tachycardia Required Intervention 1/13/2006 73 Female 93 lb 3/29/2006 Physician Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 11/1/2005 79 Female 75 lb 4/19/2006 Physician Japan
Primary
Concomitant
Unresponsive To Verbal Stimuli Hospitalization 4/1/2006 91 Female 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2004 94 Female 4/28/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 2/19/2002 81 Male 161 lb 5/16/2006 Lawyer United States
Primary
Concomitant
Gastric Cancer Hospitalization 11/1/2005 79 Female 75 lb 5/20/2006 Physician Japan
Primary
Concomitant
Sedation Hospitalization 4/1/2006 91 Female 5/22/2006 United States
Primary
Secondary
Concomitant
Gait Disturbance 4/19/2005 89 Female 5/5/2006 Other Health Professional United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2001 Female 8/15/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2001 Female 9/25/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 76 Male 170 lb 8/25/2005 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 11/23/2004 80 Male 3/21/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 5/10/2001 79 Male 5/3/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 Male 179 lb 5/29/2007 Consumer United States
Primary
Secondary
Concomitant
Pallor Hospitalization 11/20/1999 75 Male 6/1/2007 Physician Taiwan, Province Of China
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 6/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Aspiration Death 3/8/2004 86 Male 6/8/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 8/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 8/31/2007 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 9/18/2007 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2002 48 Male 9/18/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/6/2007 84 Male 9/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 4/1/2007 95 Female 9/25/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 9/13/2007 73 Female 10/3/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/3/2003 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/13/2007 73 Female 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 10/1/2007 Female 10/31/2007 Physician United States
Primary
Concomitant
Abasia Other Serious 7/1/2007 94 Female 11/1/2007 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 9/13/2007 Female 106 lb 11/14/2007 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 7/1/2007 Female 11/21/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2003 Female 11/28/2007 Consumer United States
Primary
Secondary
Concomitant
Physical Examination Abnormal Disability 10/17/2005 68 Male 166 lb 11/19/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/19/2007 Female 1/21/2008 Physician France
Primary
Concomitant
Tremor Hospitalization 1/8/2008 78 Male 1/22/2008 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 1/1/2008 Female 2/4/2008 Consumer United States
Primary
Concomitant
Death Death 65 Female 3/3/2008 Physician United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 78 Male 3/17/2008 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 7/11/2007 64 Male 106 lb 5/16/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 70 Female 87 lb 5/27/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 74 Female 129 lb 5/29/2008 Physician Switzerland
Primary
Concomitant
Interacting
Wheelchair User Disability Female 165 lb 5/30/2008 Consumer United States
Primary
Concomitant
Wheelchair User Disability Female 165 lb 6/5/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 70 Female 87 lb 7/3/2008 United States
Primary
Concomitant
Dystonia Hospitalization 1/1/2003 76 Female 7/23/2008 France
Primary
Secondary
Concomitant
Pericarditis Hospitalization 7/2/2008 Female 210 lb 7/15/2008 Physician United States
Primary
Concomitant
Pleurothotonus Hospitalization 8/1/2003 76 Female 7/25/2008 Germany
Primary
Secondary
Concomitant
Pleurothotonus Hospitalization 1/1/2003 76 Female 7/30/2008 Physician France
Primary
Concomitant
Dystonia Hospitalization 1/1/2003 76 Female 8/4/2008 France
Primary
Secondary
Concomitant
Vascular Dementia Other Serious 12/15/2004 79 Male 8/18/2008 Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 7/31/2008 Female 9/29/2008 Consumer United States
Primary
Concomitant
Agranulocytosis Hospitalization 10/1/2008 Female 11/3/2008 Other Health Professional France
Primary
Secondary
Agranulocytosis Hospitalization 10/1/2008 Female 11/6/2008 Other Health Professional France
Primary
Secondary
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Parkinsonism Hospitalization 7/1/2008 73 Female 130 lb 11/4/2008 Physician Canada
Primary
Concomitant
Agranulocytosis Hospitalization Female 11/14/2008 Other Health Professional France
Primary
Secondary
Unresponsive To Stimuli Other Serious 8/2/2008 74 Male 11/21/2008 Physician Germany
Primary
Concomitant
Interacting
Agranulocytosis Hospitalization Female 11/30/2008 Other Health Professional France
Primary
Secondary
Agranulocytosis Hospitalization 10/1/2008 Female 11/28/2008 Physician France
Primary
Concomitant
Lipase Increased Life Threatening 6/10/2008 Male 214 lb 12/17/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/5/2008 91 Female 12/17/2008 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 12/20/2008 81 Female 1/5/2009 Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/5/2008 Female 130 lb 1/5/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/26/2008 Male 173 lb 1/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Hospitalization 11/13/2007 Female 1/23/2009 Consumer United States
Primary
Concomitant
Joint Contracture Other Serious 1/1/2003 Female 1/23/2009 Consumer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/13/2007 Female 1/27/2009 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 11/13/2007 Female 2/10/2009 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 11/13/2007 Female 2/4/2009 Consumer United States
Primary
Concomitant
Palpitations Hospitalization 12/20/2008 81 Female 3/27/2009 Japan
Primary
Concomitant
Hospitalisation Hospitalization 3/29/2009 Male 3/31/2009 Physician United States
Primary
Concomitant
Vaginal Cyst Other Serious 9/4/1998 76 Female 167 lb 4/21/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 7/24/2008 80 Male 8/4/2008 Other Health Professional United States
Primary
Concomitant
Physical Assault Other Serious 1/1/2008 Male 6/9/2009 Physician United States
Primary
Concomitant
Off Label Use Other Serious 2/23/2009 78 Male 6/12/2009 Physician United States
Primary
Concomitant
Surgery Hospitalization 82 Female 6/22/2009 United States
Primary
Concomitant
Social Problem Death 81 Female 7/14/2009 United States
Primary
Concomitant
Social Avoidant Behaviour Death 80 Female 7/20/2009 United States
Primary
Concomitant
Physical Assault Other Serious 1/1/2008 Male 152 lb 7/23/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Other Serious 12/8/2004 86 Female 100 lb 7/29/2009 United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Urine Output Increased Other Serious Female 140 lb 8/21/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/3/2003 71 Female 87 lb 9/7/2009 United States
Primary
Concomitant
Social Problem Hospitalization 78 Female 160 lb 9/2/2009 United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 78 Female 160 lb 9/3/2009 United States
Primary
Concomitant
Injury Other Serious 1/1/2008 Male 152 lb 9/15/2009 Physician United States
Primary
Concomitant
Hyperglycaemia Disability Female 166 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 49 Male 176 lb 9/23/2009 United States
Primary
Concomitant
Cardiac Arrest Death 10/1/2009 58 Male 10/7/2009 Physician Thailand
Primary
Concomitant
Off Label Use Other Serious 9/29/2009 Male 10/9/2009 Physician Thailand
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2002 55 Male 10/29/2009 United States
Primary
Concomitant
Somnolence Hospitalization 9/1/2009 Male 11/2/2009 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 78 Male 12/1/2009 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/7/2009 89 Male 151 lb 12/14/2009 Pharmacist United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 9/29/2009 58 Male 1/21/2010 Physician Thailand
Primary
Concomitant
Tremor Other Serious 11/23/2004 Male 1/21/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 11/1/2004 Male 65 lb 1/22/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 11/23/2004 Male 2/22/2010 Consumer United States
Primary
Concomitant
Intentional Drug Misuse 10/19/2006 85 Female 3/16/2010 Physician United States
Primary
Concomitant
Off Label Use Death 1/1/2008 73 Female 140 lb 4/30/2010 Physician United States
Primary
Secondary
Concomitant
Sedation Other Serious Female 136 lb 5/6/2010 Physician United States
Primary
Secondary
Concomitant
Sedation Other Serious 9/1/2008 65 Female 5/28/2010 Physician Canada
Primary
Concomitant
Weight Increased Hospitalization 12/29/1997 46 Female 214 lb 6/1/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/3/2003 71 Female 87 lb 6/23/2010 United States
Primary
Concomitant
Nausea 10/29/2007 62 Male 189 lb 7/17/2010 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 6/13/2009 79 Male 180 lb 7/12/2010 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 85 Female 7/26/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 11/26/2008 86 Male 172 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization Female 8/6/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 42 Female 278 lb 8/11/2010 United States
Primary
Concomitant
Tremor Hospitalization Female 8/17/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 42 Female 335 lb 8/31/2010 United States
Primary
Concomitant
Vitamin B12 Decreased Required Intervention 74 Male 220 lb United States
Primary
Secondary
Tremor Hospitalization Female 8/31/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious Female 9/17/2010 United States
Primary
Concomitant
Hyperglycaemia Disability Female 166 lb 9/20/2010 United States
Primary
Concomitant
Pancreatitis Other Serious Male 200 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2004 67 Female 165 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 8/24/2006 59 Male 192 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2005 52 Male 255 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 7/31/2010 90 Male 9/30/2010 Physician France
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization Female 132 lb 10/8/2010 Physician United States
Primary
Concomitant
Tooth Infection Other Serious 1/1/2006 81 Male 140 lb 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 1/1/2000 75 Male 140 lb 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/5/2003 72 Male 205 lb 10/29/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious Female 10/28/2010 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 10/10/2010 76 Female 11/16/2010 Physician Japan
Primary
Concomitant
Tremor Hospitalization 1/1/2000 76 Male 140 lb 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Impairment Other Serious Female 12/8/2010 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization Female 12/24/2010 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 11/5/2010 87 Male 161 lb 1/21/2011 Physician United States
Primary
Concomitant
Contusion Death 84 Male 1/27/2011 United States
Primary
Concomitant
Pneumonia Hospitalization 1/2/2011 73 Male 3/2/2011 Physician United States
Primary
Concomitant
Rib Fracture Other Serious Male 3/10/2011 United States
Primary
Concomitant
Cardio-respiratory Arrest Death 84 Male 3/25/2011 United States
Primary
Concomitant
Flat Affect 2/1/2011 77 Female 4/15/2011 Consumer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 1/1/2000 76 Female 5/4/2011 Physician Canada
Primary
Concomitant
Altered State Of Consciousness Hospitalization 12/7/2010 Female 116 lb 5/17/2011 Physician Switzerland
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 12/7/2010 64 Female 116 lb 5/18/2011 Physician Switzerland
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 12/7/2010 64 Female 116 lb 5/20/2011 Physician Switzerland
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 12/7/2010 64 Female 116 lb 5/23/2011 Physician Switzerland
Primary
Secondary
Concomitant
Convulsion Life Threatening 1/22/2010 61 Male 138 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/11/2011 81 Male 5/27/2011 Physician Japan
Primary
Concomitant

Drug Data