Aricept combined with Toprol-XL

Reports:

---

Reaction	Outcome	Event Date	Age	Sex	Weight	Reported	Reporter	Country	Treatment
									Role	Name
Soft Tissue Disorder	Other Serious	5/4/2005	50	Male	280 lb	1/18/2006		United States	Primary Concomitant
Upper Respiratory Tract Infection	Hospitalization	7/1/2001	78	Male	150 lb	1/24/2006	Physician	United States	Primary Concomitant
Nausea	Hospitalization	11/24/2005		Female	140 lb	1/10/2006	Pharmacist	United States	Primary Concomitant
Myocardial Infarction	Hospitalization	8/10/2004	76	Female	134 lb	2/17/2006	Physician	United States	Primary Concomitant
Gastrointestinal Haemorrhage	Other Serious	11/14/2005	97	Female		1/12/2006	Other Health Professional	United States	Primary Concomitant
Portal Vein Thrombosis	Other Serious	5/4/2005	50	Male	280 lb	3/6/2006	Physician	United States	Primary Concomitant
Pneumonia	Hospitalization	3/6/2003	80	Male	147 lb	3/13/2006		United States	Primary Concomitant
Renal Failure	Hospitalization	3/1/2006		Female	115 lb	3/23/2006	Consumer	United States	Primary Concomitant
International Normalised Ratio Increased	Life Threatening	4/11/2006	88	Female	77 lb	4/11/2006	Pharmacist	United States	Primary Secondary Concomitant
Pain In Extremity	Hospitalization		79	Female		4/14/2006	Consumer	United States	Primary Concomitant
Dizziness		12/1/2005	85	Male		1/25/2006	Consumer	United States	Primary Concomitant
Pyrexia	Hospitalization	4/9/2004	87	Female	132 lb	4/28/2006	Physician	United States	Primary Secondary Concomitant
Renal Failure	Hospitalization	1/1/2000	90	Female	157 lb	4/28/2006	Physician	United States	Primary Concomitant
Weight Decreased	Other Serious	11/1/2005		Male		4/26/2006	Consumer	United States	Primary Secondary Concomitant
Syncope	Hospitalization	11/1/2005	79	Female		5/10/2006	Consumer	United States	Primary Concomitant
Pyrexia	Hospitalization	4/9/2004	87	Female	132 lb	5/17/2006	Physician	United States	Primary Secondary Concomitant
Pyrexia	Hospitalization	4/9/2004	87	Female	132 lb	5/23/2006	Physician	United States	Primary Secondary Concomitant
Pneumonia	Hospitalization	3/6/2003	75	Male	147 lb	5/17/2006	Physician	United States	Primary Concomitant
Ventricular Extrasystoles	Hospitalization	6/29/2004	85	Female	119 lb	5/9/2006	Physician	United States	Primary Concomitant
Pyrexia	Hospitalization	4/9/2004	87	Female	132 lb	6/12/2006	Physician	United States	Primary Secondary Concomitant
Cough		2/3/2006	76	Male		5/5/2006	Consumer	United States	Primary Concomitant
Pyrexia	Hospitalization	4/1/2004	87	Female	132 lb	6/27/2006	Physician	United States	Primary Secondary Concomitant
Temporal Arteritis	Other Serious	1/1/2005	89	Female	128 lb	7/10/2006	Physician	United States	Primary Concomitant
Vomiting	Disability		86	Female		7/27/2006	Physician	United States	Primary Concomitant
Weight Decreased	Other Serious		89	Female	128 lb	7/28/2006	Physician	United States	Primary Concomitant
International Normalised Ratio Increased			78	Female	174 lb	8/1/2006	Consumer	United States	Primary Concomitant
Wrist Fracture	Other Serious	5/1/2006	78	Male	121 lb	8/7/2006	Consumer	United States	Primary Concomitant
Dementia Alzheimer's Type	Other Serious		83	Male	180 lb	8/9/2006		United States	Primary Concomitant
Tremor	Required Intervention	1/1/2002	75	Male		8/21/2006	Physician	United States	Primary Secondary Concomitant
Drug Ineffective		2/7/2006	69	Female	181 lb	9/6/2006	Consumer	United States	Primary Concomitant
Tremor	Other Serious	1/1/2002	75	Male		9/1/2006	Other Health Professional	United States	Primary Secondary Concomitant
Tremor	Other Serious	1/1/2002	75	Male		9/1/2006	Other Health Professional	United States	Primary Secondary Concomitant
Weight Increased	Other Serious	1/1/2006	55	Female		9/25/2006		United States	Primary Secondary Concomitant
Dizziness		5/1/2006	87	Male		7/31/2006	Consumer	United States	Primary Secondary Concomitant
Tremor		5/12/2006	63	Male		7/31/2006	Physician	United States	Primary Concomitant
Somnolence		6/22/2006	86	Female		7/31/2006	Consumer	United States	Primary Concomitant
Respiratory Rate Increased		11/1/2005	87	Female		7/31/2006	Consumer	United States	Primary Concomitant
Weight Decreased	Other Serious		89	Female	128 lb	10/13/2006	Physician	United States	Primary Concomitant
Lung Neoplasm Malignant		6/1/2006	80	Male		8/22/2006		United States	Primary Concomitant
Ventricular Extrasystoles	Other Serious	8/23/2006	77	Female		10/19/2006	Physician	United States	Primary Secondary Concomitant
Drug Ineffective	Other Serious	6/1/2004		Female	163 lb	10/23/2006		United States	Primary Concomitant
Hypoglycaemia	Other Serious	6/1/2004		Female	163 lb	11/16/2006	Other Health Professional	United States	Primary Concomitant
Insomnia	Other Serious		89	Female	107 lb	12/11/2006	Physician	United States	Primary Concomitant
Nocturia			87	Female		9/12/2006		United States	Primary Concomitant
Weight Decreased	Other Serious	5/1/2006		Female	150 lb	1/9/2007	Consumer	United States	Primary Secondary Concomitant
Ventricular Extrasystoles	Other Serious	8/23/2006	77	Female		1/5/2007	Physician	United States	Primary Secondary Concomitant
Gait Disturbance		5/1/2006	81	Female		11/7/2006	Consumer	United States	Primary Concomitant
Respiratory Rate Increased		11/1/2005	87	Female		11/7/2006	Consumer	United States	Primary Concomitant
Weight Decreased	Hospitalization	1/1/2005	93	Female	104 lb	11/7/2006	Consumer	United States	Primary Concomitant
Urinary Tract Infection	Hospitalization	4/1/2006	90	Female		11/7/2006	Consumer	United States	Primary Concomitant
Lung Neoplasm Malignant		6/1/2006	80	Male		11/21/2006		United States	Primary Concomitant
Restlessness	Other Serious		94	Male		8/19/2005		United States	Primary Concomitant
Wound	Life Threatening	12/20/2006	95	Male	195 lb	3/1/2007	Pharmacist	United States	Primary Concomitant
Pollakiuria		8/1/2006	82	Male		12/6/2006	Consumer	United States	Primary Concomitant
Extrapyramidal Disorder	Hospitalization	9/1/2004	87	Female	170 lb	8/25/2005	Other Health Professional	United States	Primary Concomitant
Respiration Abnormal	Death	4/8/2007	71	Male		4/19/2007		United States	Primary Concomitant
Syncope	Hospitalization	5/1/2006	92	Male	153 lb	2/22/2007	Consumer	United States	Primary Concomitant
Vomiting	Hospitalization	4/2/2007	72	Male	173 lb	5/30/2007	Physician	United States	Primary Concomitant
Lung Neoplasm Malignant	Other Serious	4/20/2007		Female	134 lb	6/7/2007	Consumer	United States	Primary Concomitant
Extravasation	Required Intervention	2/1/2007	55	NotSpecified	260 lb	4/5/2007	Pharmacist	United States	Primary Concomitant
Tardive Dyskinesia	Hospitalization	12/1/2006	85	Female		7/31/2007	Physician	United States	Primary Concomitant
Parkinson's Disease	Hospitalization	5/28/2006	78	Male		8/3/2007	Pharmacist	United States	Primary Secondary Concomitant
Platelet Count Decreased	Hospitalization	5/12/2006	89	Female		8/8/2007	Pharmacist	United States	Primary Concomitant
Sedation	Other Serious		86	Female	150 lb	9/17/2007	Consumer	United States	Primary Concomitant
Hepatic Cancer Metastatic	Other Serious	5/9/2005		Male	311 lb	9/18/2007	Physician	United States	Primary Concomitant
Swollen Tongue	Hospitalization	9/17/2007	86	Female	121 lb	9/18/2007	Pharmacist	United States	Primary Concomitant
Loss Of Consciousness	Other Serious	9/2/2007	76	Female		9/25/2007	Consumer	United States	Primary Concomitant
Loss Of Consciousness	Other Serious	9/2/2007		Female		10/30/2007	Physician	United States	Primary Concomitant
Skin Laceration	Hospitalization	10/28/2007		Male		11/16/2007	Consumer	United States	Primary Concomitant
Somnolence	Hospitalization	9/14/2007	86	Female	121 lb	12/11/2007	Other Health Professional	United States	Primary Secondary Concomitant
Hyperhidrosis	Hospitalization	11/1/2007		Male		12/19/2007	Consumer	United States	Primary Concomitant
Weight Decreased	Hospitalization	1/1/2005	93	Female	104 lb	11/20/2007	Consumer	United States	Primary Concomitant
Palpitations	Hospitalization	1/1/2007		Male		1/14/2008	Consumer	United States	Primary Concomitant
Weight Increased	Hospitalization		59	Male		1/22/2008	Consumer	United States	Primary Secondary Concomitant
Palpitations	Hospitalization	1/1/2007		Male		1/23/2008	Consumer	United States	Primary Concomitant
Urinary Incontinence	Other Serious		84	Female		5/15/2008	Consumer	United States	Primary Secondary Concomitant
Catatonia	Other Serious		84	Female		5/29/2008	Consumer	United States	Primary Secondary Concomitant
Cerebrovascular Accident	Other Serious		61	Male		5/20/2008	Physician	United States	Primary Secondary Concomitant
Cerebrovascular Accident	Death	12/1/2007	84	Female	100 lb	6/3/2008		United States	Primary Concomitant
Jaundice	Hospitalization	4/8/2008		Female		6/18/2008	Physician	United States	Primary Concomitant
Vomiting	Hospitalization	7/15/2008	68	Male	135 lb	7/28/2008	Other Health Professional	United States	Primary Concomitant
Eye Pruritus		6/1/2008	61	Female		8/5/2008	Consumer	United States	Primary Concomitant
Photophobia		6/1/2008	61	Female	176 lb	8/26/2008	Physician	United States	Primary Concomitant
Colitis	Hospitalization	8/31/2008		Male	170 lb	10/1/2008	Physician	United States	Primary Concomitant
Colitis	Hospitalization	8/31/2008		Male	170 lb	10/8/2008	Physician	United States	Primary Concomitant
Loss Of Consciousness			84	Female	99 lb	10/20/2008	Physician		Primary Concomitant
Ischaemic Stroke	Hospitalization	4/22/2006		Male		10/23/2008	Physician	United States	Primary Secondary Concomitant
Urinary Incontinence	Other Serious		84	Female		9/29/2008		United States	Primary Secondary Concomitant
Ischaemic Stroke	Hospitalization	4/22/2006		Male		11/3/2008	Physician	United States	Primary Secondary Concomitant
Herpes Zoster	Other Serious	10/1/2008	85	Female	120 lb	11/4/2008	Consumer	United States	Primary Concomitant
Visual Impairment	Hospitalization		86	Female		10/29/2008		United States	Primary Concomitant
Pain	Other Serious	10/1/2006		Male	165 lb	11/12/2008	Consumer	United States	Primary Concomitant
Sensation Of Heaviness		9/29/2008	69	Female		10/20/2008	Other Health Professional	United States	Primary Concomitant
Herpes Zoster	Other Serious	10/1/2008	85	Female	120 lb	12/29/2008	Consumer	United States	Primary Concomitant
Syncope	Other Serious	11/21/2008	78	Female		12/24/2008	Other Health Professional	United States	Primary Concomitant
Unresponsive To Stimuli	Hospitalization	5/18/2008	82	Female		12/30/2008		United States	Primary Concomitant
Tremor	Hospitalization	11/6/2008		Female	164 lb	1/16/2009	Consumer	United States	Primary Concomitant
Tremor	Hospitalization	11/6/2008		Female	164 lb	1/23/2009	Consumer	United States	Primary Concomitant
Drug Interaction	Hospitalization	11/26/2007	75	Male	209 lb	2/19/2009	Physician	United States	Primary Interacting
Cerebrovascular Accident	Hospitalization	11/1/2007	79	Female	160 lb	3/6/2009	Consumer	United States	Primary Concomitant
Vomiting	Other Serious	3/15/2009		Female		3/24/2009	Consumer	United States	Primary Concomitant
Lethargy	Death	3/22/2009	88	Female	200 lb	3/25/2009	Physician	United States	Primary Concomitant
Presyncope	Other Serious	11/21/2008	78	Female		5/22/2009	Other Health Professional	United States	Primary Concomitant
Surgery	Hospitalization		82	Female		6/22/2009		United States	Primary Concomitant
Speech Disorder	Disability	5/11/2009		Male	213 lb	6/12/2009	Physician	United States	Primary Secondary Concomitant
Sudden Cardiac Death	Death	6/14/2009	60	Male	176 lb	7/2/2009	Other Health Professional	United States	Primary Concomitant
Cerebrovascular Accident	Hospitalization	11/1/2007	79	Female	160 lb	7/16/2009	Other Health Professional	United States	Primary Concomitant
Social Problem	Death		81	Female		7/14/2009		United States	Primary Concomitant
Social Avoidant Behaviour	Death		80	Female		7/20/2009		United States	Primary Concomitant
Pancreatitis	Other Serious	12/8/2004	86	Female	100 lb	7/29/2009		United States	Primary Concomitant
Therapy Cessation	Hospitalization	5/28/2009	75	Male		7/31/2009	Other Health Professional	United States	Primary Concomitant
Vomiting	Hospitalization		85	Female		8/3/2009		United States	Primary Concomitant
Incorrect Dose Administered	Other Serious		92	Female		8/20/2009	Pharmacist	United States	Primary Concomitant
Ischaemic Stroke	Hospitalization	4/22/2006		Male		8/28/2009	Physician	United States	Primary Secondary Concomitant
Weight Decreased	Hospitalization		80	Female		8/31/2009		United States	Primary Concomitant
Social Problem	Hospitalization		78	Female	160 lb	9/2/2009		United States	Primary Concomitant
Ventricular Fibrillation	Required Intervention		78	Female	160 lb	9/3/2009		United States	Primary Concomitant
Type 2 Diabetes Mellitus	Other Serious	1/1/2001	72	Female	181 lb	10/5/2009		United States	Primary Concomitant
Unresponsive To Stimuli	Hospitalization		79	Male		10/10/2009		United States	Primary Concomitant
Weight Increased	Hospitalization		72	Male		11/9/2009	Lawyer	United States	Primary Concomitant
Unresponsive To Stimuli	Hospitalization		79	Male		11/9/2009		United States	Primary Concomitant
Vomiting	Death	9/2/2008	69	Male	115 lb	11/20/2009		United States	Primary Concomitant
Unresponsive To Stimuli	Hospitalization		79	Male		11/18/2009		United States	Primary Concomitant
Unevaluable Event	Hospitalization		63	Male		11/16/2009		United States	Primary Concomitant
Weight Increased	Hospitalization		72	Male		11/17/2009	Lawyer	United States	Primary Concomitant
Platelet Count Decreased	Other Serious	9/9/2009		Female		12/1/2009	Physician	United States	Primary Concomitant
Vomiting	Hospitalization		63	Male		11/24/2009		United States	Primary Concomitant
Palpitations	Hospitalization	1/1/2007		Male		11/30/2009	Consumer	United States	Primary Concomitant
Vomiting	Hospitalization		63	Male		12/1/2009	Lawyer	United States	Primary Concomitant
Peritonitis Bacterial	Hospitalization		75	Male		11/3/2009	Other Health Professional	United States	Primary Concomitant
Neoplasm Malignant	Other Serious	5/26/2009		Female	169 lb	12/20/2009	Consumer	United States	Primary Concomitant Interacting
Vomiting	Hospitalization		63	Male		1/12/2010		United States	Primary Concomitant
Vomiting	Death	9/2/2008	69	Male	115 lb	1/29/2010		United States	Primary Secondary Concomitant
Weight Increased	Hospitalization		72	Male		1/22/2010	Lawyer	United States	Primary Concomitant
Wheezing	Hospitalization		79	Male		2/5/2010		United States	Primary Concomitant
Vomiting	Death	9/2/2008	69	Male	115 lb	3/9/2010		United States	Primary Secondary Concomitant
Walking Aid User	Other Serious	10/3/2006		Male		3/31/2010	Other Health Professional	United States	Primary Secondary Concomitant
Walking Aid User	Other Serious	10/3/2006	73	Male		4/30/2010	Other Health Professional	United States	Primary Secondary Concomitant
Walking Aid User	Other Serious	10/3/2006	73	Male		5/18/2010	Other Health Professional	United States	Primary Secondary Concomitant
Walking Aid User	Other Serious	10/3/2006	73	Male		6/1/2010	Other Health Professional	United States	Primary Secondary Concomitant
Myositis	Hospitalization	1/1/2010	78	Female		6/16/2010	Other Health Professional	United States	Primary Concomitant
Walking Aid User	Other Serious	10/3/2006	73	Male		6/25/2010		United States	Primary Secondary Concomitant
Respiratory Rate Increased	Other Serious		84	Male		7/8/2010	Lawyer	United States	Primary Secondary Concomitant
Walking Aid User	Other Serious	10/3/2006	73	Male		7/8/2010		United States	Primary Secondary Concomitant
Nervousness		10/17/2006	67	Male	163 lb	7/8/2010	Consumer	United States	Primary Concomitant
Headache		4/1/2007	84	Female	100 lb	7/12/2010	Consumer	United States	Primary Concomitant
Road Traffic Accident	Other Serious	5/7/2010	70	Female		7/14/2010	Consumer	United States	Primary Concomitant
Sensory Loss	Other Serious	11/18/2004	74	Female	121 lb	7/30/2010	Physician	United States	Primary Concomitant
Transient Ischaemic Attack	Other Serious	11/18/2004	74	Female	121 lb	8/2/2010	Physician	United States	Primary