Aricept combined with Digoxin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased Hospitalization 11/29/2005 92 Female 1/3/2006
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
Renal Cyst Hospitalization 9/1/2001 87 Female 93 lb 1/5/2006 Physician Canada
Primary
Concomitant
Renal Haematoma Hospitalization 11/29/2005 92 Female 1/10/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/17/2005 80 Female 1/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Renal Haematoma Hospitalization 11/29/2005 92 Female 1/13/2006 Physician France
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 66 Male 216 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Sudden Death Death 2/4/2003 82 Male 1/17/2006 Physician France
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/1/2005 83 Female 1/19/2006 Physician Czech Republic
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2005 81 Male 120 lb 2/2/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 66 Male 216 lb 2/22/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 11/14/2005 97 Female 1/12/2006 Other Health Professional United States
Primary
Concomitant
Haematoma Life Threatening 6/26/2005 82 Female 1/10/2006 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 1/1/2006 Male 2/27/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 66 Male 216 lb 3/3/2006 Physician United States
Primary
Concomitant
Perforated Ulcer Hospitalization 9/21/2004 81 Male 146 lb 1/21/2005 Consumer United States
Primary
Concomitant
Skin Maceration Hospitalization 12/31/2005 89 Female 168 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Tremor Death 2/1/2006 82 Female 3/21/2006 Physician Japan
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 4/10/2006 82 Female 177 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/4/2002 75 Male 4/19/2006 Physician United States
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 12/4/2002 75 Male 4/20/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/5/2005 86 Male 1/25/2006 Consumer United States
Primary
Concomitant
Tremor Death 2/25/2006 82 Female 4/26/2006 Physician Japan
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/12/2005 67 Male 368 lb 12/27/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 9/21/2004 80 Male 165 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Endophthalmitis Other Serious 12/9/2005 99 Female 4/4/2006 Other Health Professional United States
Primary
Concomitant
Lethargy Other Serious 5/1/2006 78 Male 6/14/2006 Consumer United States
Primary
Concomitant
Headache 1/20/2006 94 Female 5/5/2006 Consumer United States
Primary
Concomitant
Fatigue 1/10/2006 84 Female 5/5/2006 Consumer United States
Primary
Concomitant
Acute Pulmonary Oedema Death 1/23/2006 87 Female 71 lb 6/21/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 7/7/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 7/19/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 79 Female 88 lb 8/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/3/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/3/2006 Physician Japan
Primary
Concomitant
Urinary Incontinence 2/10/2006 Male 125 lb 8/8/2006 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 5/1/2006 78 Male 121 lb 8/7/2006 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 5/29/2006 Female 64 lb 8/14/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 8/16/2006 Physician Japan
Primary
Concomitant
Tremor Hospitalization 11/15/2002 75 Male 8/18/2006 Physician United States
Primary
Concomitant
Water Intoxication Hospitalization 6/22/2006 81 Female 8/17/2006 Physician France
Primary
Secondary
Concomitant
Tremor Required Intervention 1/1/2002 75 Male 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2002 75 Male 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2002 75 Male 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Hospitalization 6/24/2006 85 Female 127 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 5/29/2006 Female 64 lb 10/3/2006 Physician Japan
Primary
Concomitant
Retching 9/1/2005 78 Female 7/31/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2006 71 Female 115 lb 10/24/2006 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected 89 Female 10/30/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 10/4/2006 65 Male 180 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Convulsion Other Serious 1/1/2006 51 Male 306 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Convulsion Required Intervention 12/1/2006 51 Male 306 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 10/2/2006 85 Male 12/18/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/1/2006 Female 150 lb 1/9/2007 Consumer United States
Primary
Secondary
Concomitant
Convulsion Other Serious 12/1/2006 51 Male 306 lb 1/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Gait Disturbance 5/1/2006 81 Female 11/7/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 4/1/2005 77 Male 150 lb 1/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 79 Female 88 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 11/15/2006 94 Female 2/12/2007 Other Health Professional France
Primary
Secondary
Transient Ischaemic Attack Death 12/20/2005 Female 110 lb 3/8/2007 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 11/15/2006 94 Female 3/5/2007 Other Health Professional France
Primary
Secondary
Hepatitis Hospitalization 1/29/2006 71 Female 4/4/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Vomiting Hospitalization 71 Female 4/5/2007 Pharmacist Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/29/2006 71 Female 4/5/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatitis Hospitalization 1/29/2006 71 Female 4/11/2007 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 1/29/2006 71 Female 4/11/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/29/2006 71 Female 3/30/2007 Spain
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/4/2007 77 Male 4/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 4/4/2007 77 Male 5/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 8/24/2006 88 Female 5/25/2007 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 6/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Bradycardia Life Threatening 5/19/2007 93 Male 126 lb 7/9/2007 Physician France
Primary
Concomitant
Transient Ischaemic Attack Death 12/20/2005 Female 110 lb 7/17/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 4/4/2007 77 Male 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 10/1/2006 82 Female 130 lb 7/9/2007 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/28/2007 Female 100 lb 7/16/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 Female 8/8/2007 Lawyer United States
Primary
Secondary
Concomitant
Tongue Dry Hospitalization 7/29/2007 85 Female 8/25/2007 France
Primary
Secondary
Concomitant
Tongue Dry Hospitalization 7/29/2007 85 Female 8/28/2007 France
Primary
Secondary
Concomitant
Tongue Dry Hospitalization 7/29/2007 85 Female 8/20/2007 France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 8/31/2007 Lawyer United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 78 Male 8/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 Female 9/18/2007 Lawyer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Required Intervention 6/1/2007 80 Female 176 lb 9/14/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 9/6/2007 84 Male 9/24/2007 Consumer United States
Primary
Concomitant
Malnutrition Hospitalization 7/29/2007 85 Female 9/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 11/3/2003 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 5/1/2007 82 Female 10/10/2007 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 6/21/2003 69 Female 181 lb 11/2/2007 Physician United States
Primary
Concomitant
Skin Laceration Hospitalization 10/28/2007 Male 11/16/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/1/2003 Female 11/28/2007 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 7/19/2005 92 Female 12/5/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2006 80 Male 12/21/2007 Consumer United States
Primary
Concomitant
Sedation Hospitalization 11/7/2007 82 Female 146 lb 3/3/2008 Pharmacist United States
Primary
Secondary
Concomitant
Polyarthritis Other Serious 1/17/2005 84 Female 71 lb 3/20/2008 Physician Japan
Primary
Concomitant
Pelvic Fracture Other Serious 3/1/2008 80 Female 3/19/2008 Consumer Canada
Primary
Concomitant
Polyarthritis Other Serious 1/17/2005 84 Female 71 lb 3/25/2008 Physician Japan
Primary
Concomitant
Syncope Hospitalization 2/26/2008 85 Female 3/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/26/2007 Female 216 lb 4/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 3/15/2008 Male 4/15/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased 2/1/2008 84 Male 138 lb 4/11/2008 United States
Primary
Concomitant
Pacemaker Complication Hospitalization 12/1/2007 Male 197 lb 5/7/2008 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 4/17/2008 79 Male 5/12/2008 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 4/1/2005 77 Male 150 lb 5/20/2007 United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 3/1/2008 80 Female 92 lb 5/19/2008 Physician Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 4/14/2008 70 Male 5/29/2008 United States
Primary
Concomitant
Cerebrovascular Accident Death 12/1/2007 84 Female 100 lb 6/3/2008 United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 3/29/2008 83 Male 6/16/2008 Consumer United States
Primary
Concomitant
Sepsis Death 4/18/2008 79 Male 6/16/2008 United States
Primary
Concomitant
Head Injury Hospitalization 7/1/2007 87 Female 6/19/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious Female 104 lb 6/27/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 1/1/2008 80 Female 104 lb 6/30/2008 Consumer United States
Primary
Concomitant
Completed Suicide 9/23/2007 Male 165 lb 6/27/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 4/16/2008 90 Male 7/17/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2001 73 Female 104 lb 7/24/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 4/24/2008 75 Male 150 lb 7/16/2008 United States
Primary
Concomitant
Syncope Hospitalization 6/16/2008 Male 7/28/2008 Physician Germany
Primary
Concomitant
Malaise Death 6/30/2007 84 Male 188 lb 8/1/2008 United States
Primary
Concomitant
Respiratory Arrest Hospitalization 10/17/2007 78 Female 105 lb 8/12/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Other Serious Female 104 lb 8/20/2008 Consumer United States
Primary
Concomitant
Fall Other Serious 4/1/2008 90 Female 118 lb 8/15/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 80 Female 104 lb 8/25/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 8/1/2007 61 Female 189 lb 8/18/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/28/2008 74 Male 174 lb 8/28/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 80 Female 104 lb 9/15/2008 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 7/21/2008 79 Female 9/10/2008 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness 84 Female 99 lb 10/20/2008 Physician
Primary
Concomitant
Melaena Other Serious 81 Female 10/22/2008 Sweden
Primary
Concomitant
Herpes Zoster Other Serious 10/1/2008 85 Female 120 lb 11/4/2008 Consumer United States
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
White Blood Cell Count Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 9/11/2008 Female 120 lb 12/9/2008 Pharmacist United States
Primary
Concomitant
Herpes Zoster Other Serious 10/1/2008 85 Female 120 lb 12/29/2008 Consumer United States
Primary
Concomitant
Vision Blurred Life Threatening 87 Male 12/22/2008 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 5/18/2008 82 Female 12/30/2008 United States
Primary
Concomitant
Intentional Drug Misuse Death 92 Female 1/8/2009 United States
Primary
Secondary
Convulsion Other Serious 12/7/2006 51 Male 1/13/2009 Pharmacist United States
Primary
Secondary
Concomitant
Palpitations Hospitalization 75 Male 220 lb 1/29/2009 United States
Primary
Concomitant
Skin Burning Sensation 1/21/2009 2/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence 8/1/2008 76 Male 3/4/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/15/2009 Female 3/24/2009 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/16/2009 47 Male 5/13/2009 Physician
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 86 Female 5/7/2009 Consumer United States
Primary
Concomitant
Prostate Cancer Required Intervention 3/28/2009 85 Male 5/12/2009 United States
Primary
Concomitant
Weight Decreased Required Intervention 4/7/2009 88 Male 5/12/2009 United States
Primary
Concomitant
Syncope Death 76 Male 6/21/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 82 Female 6/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 72 Female 7/1/2009 Lawyer United States
Primary
Concomitant

Drug Data