Aredia combined with Melphalan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 6/18/1999 51 Male 1/25/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2005 60 Female 2/3/2006 Physician Spain
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/29/2006 68 Male 200 lb 2/10/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 1/23/2006 71 Female 2/17/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/1/2003 70 Male 108 lb 3/30/2006 Physician Japan
Primary
Secondary
Concomitant
Viraemia Hospitalization 1/29/2006 68 Male 200 lb 4/5/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 5/8/2006 United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 1/1/2002 70 Female 5/20/2006 United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 9/1/2001 75 Male 5/25/2006 Physician Sweden
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 6/1/2006 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2000 69 Male 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2002 70 Female 6/4/2006 Physician United States
Primary
Secondary
Concomitant
Soft Tissue Disorder Other Serious 1/1/2005 68 Male 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 Male 153 lb 6/24/2006 Physician Germany
Primary
Secondary
Concomitant
Wound Debridement Other Serious 12/1/2003 70 Male 108 lb 6/29/2006 Japan
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/23/2006 71 Female 7/5/2006 Italy
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 Male 153 lb 8/8/2006 Physician Germany
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2002 62 Male 8/16/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 75 Male 8/17/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 3/5/2002 72 Male 190 lb 9/27/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/5/2002 72 Male 190 lb 9/27/2006 Consumer United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/8/2006 43 Female 9/26/2006 Physician United States
Primary
Concomitant
Tooth Injury Other Serious 1/1/2002 65 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2000 69 Male 10/23/2006 United States
Primary
Secondary
Concomitant
Fibrosis Other Serious 8/1/2004 51 Male 10/25/2006 Physician Spain
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 11/14/2006 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 11/22/2006 United States
Primary
Secondary
Concomitant
Tooth Repair Other Serious 11/10/1998 75 Male 12/7/2006 Physician Belgium
Primary
Concomitant
Tooth Injury Other Serious 1/1/2002 65 Female 12/18/2006 Consumer United States
Primary
Secondary
Concomitant
Purulent Discharge Other Serious 5/31/2002 70 Female 161 lb 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 54 Male 1/12/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 9/1/2006 83 Female 1/12/2007 Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 77 Female 1/13/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 54 Male 1/25/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/1/2003 53 Male 167 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/1/2003 53 Male 167 lb 2/20/2007 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 3/2/2007 Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 3/15/2007 Japan
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 84 Male 3/19/2007 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2004 84 Male 4/17/2007 France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2005 73 Male 239 lb 5/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 2/1/2005 73 Male 239 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 47 Female 6/8/2007 Physician Australia
Primary
Secondary
Concomitant
Surgery Hospitalization 11/1/2006 65 Male 6/8/2007 Physician Australia
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 6/15/2007 United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 3/1/2007 67 Female 243 lb 6/15/2007 Physician Germany
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 10/12/2006 78 Male 6/23/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 3/1/2007 67 Female 243 lb 6/26/2007 Physician Germany
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 60 Female 7/20/2007 United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 7/24/2007 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 7/28/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 4/1/2007 77 Female 139 lb 8/4/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Repair Other Serious 1/1/2001 66 Male 132 lb 9/1/2007 Physician Germany
Primary
Concomitant
Stomatitis Other Serious 4/1/2007 77 Female 139 lb 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Surgery Hospitalization 11/1/2006 62 Male 10/19/2007 Physician Australia
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 10/31/2007 Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 11/12/2007 Japan
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 68 Male 201 lb 12/11/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 77 Female 12/18/2007 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 1/29/2008 Japan
Primary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 2/4/2008 Japan
Primary
Concomitant
Tooth Extraction Other Serious 9/4/2007 60 Male 2/6/2008 Physician Japan
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 2/26/2008 United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 67 Male 201 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 3/5/2008 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 8/11/2000 48 Female 192 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 11/25/1998 43 Female 170 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 8/11/2000 48 Female 192 lb 4/3/2008 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 4/8/2008 Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/7/2005 Male 4/18/2008 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 5/16/2006 70 Male 108 lb 4/22/2008 Japan
Primary
Concomitant
Skin Cancer Other Serious 2/25/2008 79 Female 4/22/2008 Physician United States
Primary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 4/30/2008 Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/12/2006 78 Male 128 lb 5/22/2008 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/4/2007 Male 123 lb 7/2/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/23/2008 Male 7/16/2008 Physician Switzerland
Primary
Secondary
Swelling Other Serious 8/2/2001 Male 200 lb 7/31/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/30/2007 71 Male 8/1/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 2/25/2008 79 Female 8/1/2008 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 5/11/2007 Female 9/9/2008 Other Health Professional France
Primary
Secondary
Concomitant
X-ray Dental Other Serious 1/1/1998 Female 9/16/2008 United States
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2004 84 Male 9/18/2008 France
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2000 Female 192 lb 10/28/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 10/29/2008 United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 2/25/2008 79 Female 11/13/2008 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2000 Female 192 lb 11/26/2008 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/18/1998 Female 125 lb 12/9/2008 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 Male 150 lb 1/13/2009 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Abscess Disability 10/1/2004 Female 1/19/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 1/30/2009 United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 11/17/2007 54 Male 2/2/2009 Physician Japan
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 2/5/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 2/19/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/1/2008 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 9/18/1998 Female 125 lb 3/6/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 3/9/2009 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 1/1/2005 Male 201 lb 4/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 5/5/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 Male 5/11/2009 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 5/16/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/1998 Male 5/20/2009 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 1/1/1998 Female 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2003 Male 5/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/20/2003 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 6/8/2009 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 6/11/2009 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious Male 7/1/2009 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 7/17/2009 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 7/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/23/2009 Male 172 lb 9/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 2/1/2003 Male 9/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2002 Male 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 10/15/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 10/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/26/2009 Female 130 lb 11/6/2009 Physician France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/26/2009 Female 130 lb 11/6/2009 Physician France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 11/10/2009 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 11/11/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 2/14/2003 Female 195 lb 11/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 11/12/2009 Physician United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 11/24/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/1999 Male 178 lb 11/25/2009 Consumer United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 12/2/2009 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 11/6/2008 Male 12/10/2009 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/1999 Female 192 lb 12/14/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 12/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2002 Female 195 lb 12/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Male 170 lb 1/20/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data