Aredia combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 1/18/2006 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 48 Female 208 lb 2/23/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 12/11/2001 52 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 Female 2/24/2006 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2003 63 Female 112 lb 2/28/2006 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/28/2002 78 Female 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 48 Female 208 lb 4/12/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2003 63 Female 112 lb 5/5/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 12/11/2001 52 Female 5/6/2006 United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 3/13/2006 52 Female 5/19/2006 France
Primary
Secondary
Pitting Oedema Hospitalization 3/13/2006 52 Female 5/17/2006 France
Primary
Secondary
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 3/13/2006 62 Female 5/24/2006 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 3/13/2006 62 6/19/2006 Physician Japan
Primary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2006 60 Female 8/12/2006 Physician Japan
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 9/11/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/1/2005 62 Female 9/9/2006 Japan
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 9/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/8/2004 50 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2006 62 Female 9/21/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 9/1/2006 25 Female 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/1/2005 62 Female 10/31/2006 Japan
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Other Serious 10/13/2006 60 Female 130 lb 11/6/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 11/20/2006 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 11/21/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Hospitalization 4/1/2006 69 Female 12/16/2006 France
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 1/8/2007 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 1/9/2007 Consumer United States
Primary
Secondary
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 8/1/2003 63 Female 112 lb 1/15/2007 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 49 Female 1/16/2007 United States
Primary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2003 62 Female 1/26/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/6/2007 Lawyer United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 1/5/2007 60 Female 2/6/2007 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 5/1/2003 56 Female 2/12/2007 Italy
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/14/2007 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 2/23/2007 Japan
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 3/8/2007 Japan
Primary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2003 63 Female 3/15/2007 Physician Japan
Primary
Concomitant
Wheezing Other Serious 1/1/2002 63 Female 112 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 7/1/2001 59 Female 11/6/2006 Consumer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 2/13/2007 79 Female 4/4/2007 Physician Germany
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 4/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Periodontitis Hospitalization 12/18/2006 70 Female 5/13/2007 Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 79 Female 6/4/2007 Physician Germany
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 6/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 6/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/6/2007 Japan
Primary
Concomitant
Lip Oedema 5/5/2007 52 Female 7/6/2007 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/11/2007 Japan
Primary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 5/10/2007 46 Female 119 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/14/2007 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Sequestrectomy Other Serious 5/10/2007 46 Female 119 lb 9/1/2007 Physician Japan
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 2/5/2007 60 Female 9/8/2007 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 3/1/2007 52 Female 9/19/2007 Physician United States
Primary
Secondary
Tooth Extraction Hospitalization 1/31/2006 63 Female 10/2/2007 Japan
Primary
Concomitant
Periodontitis Hospitalization 12/18/2006 70 Female 10/19/2007 Japan
Primary
Secondary
Concomitant
Purulence Other Serious 7/19/2007 66 Female 10/27/2007 Physician Japan
Primary
Secondary
Purulence Other Serious 7/19/2007 66 Female 10/27/2007 Physician Japan
Primary
Secondary
Tooth Extraction Other Serious 12/1/2003 46 Female 166 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 11/2/2007 Japan
Primary
Concomitant
Purulence Other Serious 7/19/2007 66 Female 11/9/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 6/1/2005 69 Female 128 lb 11/20/2007 Japan
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2007 60 Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 12/8/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2007 60 Female 12/8/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 12/11/2007 Physician
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/14/2007 Physician
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 57 Female 161 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/29/2007 Physician
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 57 Female 161 lb 1/18/2008 Physician Japan
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 2/6/2008 Physician
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 2/7/2008 Consumer United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/1/2000 66 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 3/3/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/20/2006 55 Female 3/29/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 4/12/2008 United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/1/2000 66 Female 167 lb 4/22/2008 United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 1/5/2007 60 Female 5/21/2008 Physician Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 1/5/2007 60 Female 5/22/2008 Physician Japan
Primary
Secondary
Concomitant
Vocal Cord Paralysis Other Serious 1/1/2000 Female 167 lb 6/2/2008 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/25/2007 67 Female 6/3/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/25/2007 Female 82 lb 7/2/2008 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 71 Female 117 lb 7/10/2008 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2007 Female 117 lb 7/14/2008 Other Health Professional Japan
Primary
Secondary
Toothache Other Serious 2/5/1998 Female 167 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 8/18/2008 Lawyer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/1/2008 Female 9/4/2008 Pharmacist Germany
Primary
Secondary
Concomitant
Vasospasm Other Serious 10/16/1995 Female 167 lb 9/10/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 9/23/2008 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/1/2008 Female 10/13/2008 Pharmacist Germany
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/20/2008 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/28/2008 Japan
Primary
Concomitant
Trismus Other Serious 9/1/1999 11/22/2008 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/31/2006 Female 12/2/2008 Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/18/2003 Female 12/19/2008 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/19/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Mastoid Disorder Other Serious 12/1/2007 Female 12/19/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 12/19/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 1/13/2009 Consumer United States
Primary
Secondary
Bone Disorder Other Serious 2/11/2000 Female 1/14/2009 Physician United States
Primary
Secondary
Concomitant
Loose Tooth Other Serious 8/1/2003 Female 1/15/2009 Physician United States
Primary
Secondary
Concomitant
Postmenopause Other Serious 5/2/2005 Female 1/15/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious Female 1/19/2009 Physician United States
Primary
Secondary
Concomitant
Post Procedural Complication Required Intervention 8/1/2004 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Loose Tooth Required Intervention 8/1/2003 Female 7/1/2008 Physician United States
Primary
Secondary
Concomitant
Jaw Disorder Required Intervention 11/1/2004 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Mastoid Disorder Other Serious 12/1/2007 Female 1/23/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 2/4/2009 Consumer United States
Primary
Secondary
Weight Increased Other Serious 3/3/2000 Female 208 lb 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2005 Female 180 lb 2/27/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2005 Female 180 lb 3/13/2009 Physician United States
Primary
Concomitant
Swelling Disability 1/20/2006 Female 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/3/2000 Female 208 lb 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Postmenopause Other Serious 5/2/2005 Female 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Patellofemoral Pain Syndrome Other Serious Female 4/27/2009 Physician United States
Primary
Secondary
Concomitant
Mastoid Disorder Other Serious 12/1/2007 Female 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Pain Other Serious Female 4/30/2009 Physician United States
Primary
Concomitant

Drug Data