Aredia combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 56 Male 10/27/2005 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/6/2005 53 Female 121 lb 1/24/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/15/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/7/2005 52 Female 3/17/2006 Physician Japan
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 3/24/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 4/10/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Vital Capacity Abnormal Disability 2/21/2006 Female 5/22/2006 Physician Japan
Primary
Concomitant
Wound Drainage Other Serious 1/1/2001 52 Male 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 5/31/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 6/20/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 9/28/1999 57 Female 8/8/2006 Germany
Primary
Secondary
Concomitant
Herpes Zoster Ophthalmic Hospitalization 11/7/2006 54 Male 220 lb 11/14/2006 Physician Canada
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2005 70 Male 12/7/2006 Physician Belgium
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 9/28/2006 43 Male 205 lb 12/6/2006 Other Health Professional France
Primary
Concomitant
Herpes Zoster Disseminated Hospitalization 11/7/2006 54 Male 220 lb 12/8/2006 Physician Canada
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/22/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 1/18/2007 United States
Primary
Secondary
Concomitant
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 62 Female 200 lb 3/10/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 54 Female 4/21/2007 Physician Brazil
Primary
Concomitant
Pyrexia Hospitalization 9/20/2006 52 Female 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 9/20/2006 52 Female 5/27/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/22/2007 9 Female 58 lb 6/14/2007 Physician Germany
Primary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/7/2007 66 Female 257 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/6/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/11/2007 Japan
Primary
Concomitant
Osteonecrosis Other Serious 63 Female 7/13/2007 Japan
Primary
Concomitant
Swelling Other Serious 12/1/2004 60 Male 210 lb 7/14/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2004 63 Female 7/17/2007 Japan
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 63 Female 7/20/2007 Japan
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2006 Female 8/10/2007 Switzerland
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2006 Female 8/10/2007 Switzerland
Primary
Concomitant
Toothache Other Serious 5/1/2006 65 Female 9/18/2007 Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/31/2005 71 Female 134 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 7/31/2005 71 Female 134 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/17/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/20/2007 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/22/2007 9 Female 58 lb 11/21/2007 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 12/19/2007 Japan
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 2/7/2008 Consumer United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/14/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 8/2/2001 Male 200 lb 7/31/2008 United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 7/31/2005 72 Female 134 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/2/2007 72 Female 5/30/2007 Physician United States
Primary
Secondary
Concomitant
Tracheobronchitis Hospitalization 1/24/2007 63 Female 3/19/2007 Physician United States
Primary
Secondary
Concomitant
Appendicitis Hospitalization 8/9/2007 50 Male 253 lb 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenia Required Intervention 6/20/2005 57 Male 188 lb 4/28/2008 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 Male 150 lb 1/13/2009 United States
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 71 Female 4/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 9/17/2008 Female 132 lb 4/20/2009 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 5/13/2009 Lawyer United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2005 Female 12/2/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2005 Female 12/24/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 12/31/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 12/1/2006 Male 2/1/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 2/5/2010 Physician United States
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 Male 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 8/11/2008 Male 219 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 Female 148 lb 3/25/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 Male 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 5/1/2007 Male 219 lb 3/31/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 4/12/2010 Physician United States
Primary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 4/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 5/4/2010 United States
Primary
Concomitant
Tooth Extraction Other Serious 7/16/2008 68 Female 110 lb 5/5/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 10/13/2009 70 Female 5/5/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/19/2010 65 Female 99 lb 5/17/2010 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 5/4/2010 65 Female 99 lb 5/25/2010 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 12/12/2001 65 Male 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 6/11/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 60 Female 148 lb 6/30/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2008 63 Female 97 lb 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 7/19/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/1/2007 60 Female 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 8/4/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 8/5/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 8/6/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 8/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 8/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 8/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 8/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 44 Female 134 lb 8/29/2010 United States
Primary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 60 Female 148 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2001 49 Male 150 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1995 57 Male 9/17/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 60 Female 148 lb 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 9/22/2010 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 12/12/2001 65 Male 9/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/14/1999 48 Male 9/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2001 50 Female 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/1/2007 68 Male 219 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/14/1999 48 Male 10/29/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 60 Female 148 lb 11/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/9/1997 37 Female 193 lb 11/19/2010 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 12/12/2001 65 Male 11/24/2010 United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 12/29/2000 60 Female 148 lb 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/1/2010 62 1/3/2011 Physician Australia
Primary
Concomitant
Renal Cyst Other Serious 5/9/1997 37 Female 193 lb 1/7/2011 Physician United States
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 12/29/2000 60 Female 148 lb 1/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 1/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Arthritis Other Serious Male 2/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Generalised Oedema Hospitalization 5/9/1997 37 Female 193 lb 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 3/1/2011 United States
Primary
Secondary
Concomitant
Onychomycosis Other Serious 1/22/2005 63 Female 113 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 1/1/1995 57 Male 3/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Back Pain Other Serious 5/9/1997 37 Female 193 lb 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Cyst Other Serious Male 4/8/2011 United States
Primary
Secondary
Concomitant
Haematoma Other Serious 1/22/2005 63 Female 113 lb 4/18/2011 United States
Primary
Secondary
Concomitant
Cerebral Atrophy Other Serious 1/22/2005 63 Female 113 lb 5/2/2011 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/9/1997 37 Female 193 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 12/29/2000 60 Female 148 lb 5/13/2011 Physician United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 1/1/2001 44 Female 134 lb 6/6/2011 Other Health Professional United States
Primary
Concomitant
Amyloidosis Hospitalization 1/1/2008 66 Female 119 lb 6/14/2011 Physician Switzerland
Primary
Secondary
Cardiomyopathy Hospitalization 1/1/2008 66 Female 119 lb 6/16/2011 Physician Switzerland
Primary
Secondary
Cardiomyopathy Other Serious 1/1/2008 6/17/2011 Other Health Professional Switzerland
Primary
Secondary
Herpes Zoster Other Serious 10/2/2002 47 Female 128 lb 6/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Abdominal Discomfort Other Serious 5/9/1997 37 Female 193 lb 7/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 3/14/1999 48 Male 7/7/2011 Lawyer United States
Primary
Secondary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 7/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/22/2005 63 Female 113 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 5/1/2007 68 Male 219 lb 7/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myopia Other Serious 10/2/2002 47 Female 128 lb 7/25/2011 United States
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 5/9/1997 37 Female 193 lb 7/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/22/2005 63 Female 113 lb 8/16/2011 Pharmacist United States
Primary
Secondary
Concomitant
Os Trigonum Syndrome Other Serious 5/9/1997 37 Female 193 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Density Decreased Other Serious 9/17/2009 62 Female 8/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 10/2/2002 47 Female 128 lb 9/2/2011 United States
Primary
Secondary
Concomitant
Exostosis Other Serious 1/22/2005 63 Female 113 lb 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Arthralgia Hospitalization 9/17/2009 62 Female 9/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Actinic Keratosis Other Serious 11/1/2005 56 Female 123 lb 9/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 6/14/2004 58 Female 155 lb 9/24/2011 Physician United States
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 1/1/2001 55 Female 91 lb 9/26/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data