Aranesp combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Off Label Use Death 5/11/2005 62 Female 1/12/2006 Consumer United States
Primary
Concomitant
Wound Debridement Other Serious 5/23/2005 55 Female 2/2/2006 United States
Primary
Concomitant
Neuropathy Peripheral 53 Female 2/6/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Alkalosis Other Serious 9/29/2005 60 Female 1/27/2006 France
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2005 60 Male 2/7/2006 United States
Primary
Concomitant
Pain In Jaw Other Serious 12/22/2005 81 Male 196 lb 2/10/2006 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 8/11/2004 84 Female 2/15/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Required Intervention 9/19/2005 69 Male 228 lb 2/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 9/1/2005 81 Male 196 lb 2/17/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2003 52 Female 2/18/2006 United States
Primary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 2/22/2006 United States
Primary
Secondary
Concomitant
Toothache Other Serious 9/1/2005 81 Male 196 lb 2/25/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 9/19/2005 69 Male 228 lb 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 6/1/2005 73 Male 3/1/2006 France
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 3/25/2005 52 Male 154 lb 3/3/2006 Physician United States
Primary
Concomitant
Pain Other Serious Female 3/11/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 53 Male 206 lb 3/15/2006 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Transiently Other Serious 4/15/2005 76 Male 209 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Hypertension Other Serious 1/1/2006 45 Female 112 lb 3/17/2006 Physician Germany
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2006 49 Female 162 lb 3/6/2006 Consumer United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 6/1/2005 85 Female 3/8/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 6/30/2005 59 Female 3/28/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 3/29/2006 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 11/28/2005 49 Female 3/17/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 4/4/2006 United States
Primary
Concomitant
Soft Tissue Infection Other Serious 3/1/2005 72 Male 127 lb 4/7/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2003 52 Female 4/12/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 73 Male 139 lb 4/13/2006 United States
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/24/2006 Female 4/13/2006 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/8/2006 63 Female 220 lb 4/7/2006 Physician United States
Primary
Concomitant
Streptococcal Infection Required Intervention 2/10/2006 57 Female 4/7/2006 Physician United States
Primary
Concomitant
Oligomenorrhoea Other Serious 4/20/2006 Female 143 lb 4/21/2006 United States
Primary
Secondary
Concomitant
Disease Progression Death 3/17/2006 78 Male 4/11/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2003 73 Male 139 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Tooth Impacted Other Serious 10/1/2004 87 Female 4/27/2006 Physician United States
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 6/1/2004 72 Male 127 lb 4/27/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 9/1/2005 75 Female 5/1/2006 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/25/2005 76 Male 195 lb 2/17/2006 Physician United States
Primary
Concomitant
Escherichia Urinary Tract Infection Required Intervention 4/4/2006 84 Female 149 lb 5/1/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 12/2/2005 67 Male 230 lb 5/4/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 2/4/2005 77 Male 183 lb 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 12/2/2005 67 Male 230 lb 5/11/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2004 55 Female 5/11/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2006 54 Male 5/11/2006 United States
Primary
Concomitant
Enterovesical Fistula Required Intervention 4/4/2006 84 Female 149 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/27/2006 59 Female 105 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 6/1/2005 60 Male 5/17/2006 United States
Primary
Concomitant
Swelling Other Serious 6/1/2005 60 Male 5/24/2006 Physician United States
Primary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 6/1/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/30/2005 59 Female 6/4/2006 United States
Primary
Concomitant
Pregnancy Other Serious 4/20/2006 36 Female 143 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/3/2006 53 Female 186 lb 6/14/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2006 Male 7/6/2006 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 76 Female 7/12/2006 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 80 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 38 Female 6/30/2006 United States
Primary
Concomitant
Stomatitis Other Serious 5/1/2006 64 Female 7/24/2006 Other Health Professional United States
Primary
Concomitant
Soft Tissue Infection Other Serious 1/24/2006 54 Male 7/24/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2006 59 Male 7/27/2006 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2004 53 Female 186 lb 7/31/2006 Physician United States
Primary
Concomitant
Tooth Extraction Disability 2/1/2006 76 Female 8/3/2006 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/16/2006 51 Male 170 lb 8/11/2006 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 6/1/2006 Male 159 lb 8/21/2006 Physician France
Primary
Secondary
Concomitant
Wound Debridement Hospitalization 6/1/2005 Male 141 lb 8/25/2006 Physician France
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 5/1/2006 64 Female 8/30/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2005 72 Male 9/1/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2006 59 Male 9/9/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 1/12/2006 71 Female 114 lb 9/9/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 12/7/2005 61 Male 328 lb 9/18/2006 Physician United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Death Death 51 Female 9/20/2006 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2006 59 Male 9/26/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/27/2006 52 Male 129 lb 9/15/2006 Physician United States
Primary
Secondary
Concomitant
Self-medication Hospitalization 8/18/2006 77 Male 224 lb 9/27/2006 Physician United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2006 Female 10/26/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2006 62 Female 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/4/2006 59 Male 154 lb 11/10/2006 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 10/23/2006 72 Female 100 lb 12/12/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 79 Female 11/30/2006 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 11/1/2006 93 Male 12/4/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/23/2006 Female 100 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Other Serious 1/1/2006 63 Female 12/5/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 1/8/2006 63 Female 220 lb 12/13/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Life Threatening 8/27/2006 62 Female 12/19/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 140 lb 1/5/2007 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/20/2004 54 Female 140 lb 1/5/2007 United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 1/1/2004 69 Female 142 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2004 62 Female 8/29/2006 Physician United States
Primary
Concomitant
Ureteric Obstruction Other Serious 5/5/2004 83 Male 8/29/2006 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/19/2006 Male 167 lb 1/4/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Male 144 lb 12/29/2006 Physician United States
Primary
Concomitant
Tooth Extraction Disability 9/17/2004 74 Female 104 lb 1/11/2007 France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Male 144 lb 1/8/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 10/23/2006 73 Female 100 lb 1/18/2007 United States
Primary
Secondary
Dyspnoea Required Intervention 7/7/2005 48 Female 226 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 3/14/2006 71 Male 1/10/2007 Physician United States
Primary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 121 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/28/2002 Female 2/5/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/28/2002 Female 2/5/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 2/10/2007 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/23/2007 Male 147 lb 2/28/2007 Physician United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/23/2007 53 Male 2/23/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/12/2007 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/23/2007 53 Male 147 lb 3/7/2007 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 3/1/2007 Male 156 lb 3/27/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/28/2007 62 NotSpecified 259 lb 3/6/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 11/23/2001 52 Female 178 lb 3/28/2007 Lawyer United States
Primary
Concomitant
Toothache Other Serious 12/1/2005 71 Male 3/28/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2002 53 Female 4/5/2007 Lawyer United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 127 lb 4/11/2007 United States
Primary
Concomitant
Thrombophlebitis Hospitalization 2/1/2007 53 Male 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 3/1/2007 Male 156 lb 4/17/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/1/2007 53 Male 4/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/28/2007 62 259 lb 4/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 11/9/2006 Male 95 lb 4/27/2007 Physician France
Primary
Concomitant
Transfusion Required Intervention 8/5/2006 65 Female 91 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Lacrimation Increased 1/1/2006 Male 2/16/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/28/2007 62 259 lb 5/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 3/19/2005 79 Male 3/30/2005 Physician United States
Primary
Secondary
Concomitant
Disturbance In Attention Hospitalization 2/8/2005 79 Male 179 lb 2/9/2005 Physician United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 5/5/2005 52 Male 162 lb 5/5/2005 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/1/2007 58 Male 6/5/2007 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 5/30/2007 73 Female 6/12/2007 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased 1/1/2007 Male 6/26/2007 Consumer United States
Primary
Concomitant
Weight Decreased Required Intervention 3/8/2007 73 Male 177 lb 6/20/2007 Physician United States
Primary
Concomitant
Rash Other Serious 8/18/2006 88 Male 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/23/2006 72 Female 100 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 7/12/2007 Lawyer United States
Primary
Concomitant
Osteonecrosis Other Serious 5/16/2007 69 Male 7/12/2007 Italy
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 7/5/2006 70 Male 8/3/2007 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 8/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 8/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2007 74 Female 9/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death 5/1/2007 68 Male 8/23/2007 Physician France
Primary
Concomitant
Sepsis Life Threatening 7/4/2006 Male 154 lb 9/21/2007 Germany
Primary
Concomitant
Prostate Cancer Metastatic Hospitalization 9/12/2007 Male 194 lb 9/21/2007 Physician United States
Primary
Concomitant
Sepsis Life Threatening 7/4/2006 Male 154 lb 9/27/2007 Germany
Primary
Concomitant
Oral Herpes 1/1/2007 59 Female 122 lb 10/11/2007 Other Health Professional United States
Primary
Concomitant
Ulcer Other Serious 6/1/2003 79 Male 200 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/11/2004 84 Female 11/16/2007 United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 9/22/2007 Male 11/21/2007 Greece
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/22/2005 Male 165 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency 8/20/2002 Female 130 lb 12/15/2007 Physician United States
Primary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 121 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Death Death 54 Female 12/24/2007 Other Health Professional United States
Primary
Concomitant

Drug Data