Aranesp combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Refractory Anaemia Other Serious 10/20/2005 14 Female 79 lb 2/3/2006 Physician France
Primary
Concomitant
Thrombocytopenia Other Serious 3/12/2005 Male 247 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 4/1/2005 Female 126 lb 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Increased Other Serious Male 3/6/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 Male 3/14/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Other Serious 4/1/2005 Female 126 lb 3/21/2006 Physician United States
Primary
Secondary
Concomitant
Parvovirus B19 Serology Positive Other Serious 4/1/2005 Female 126 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 10/14/2005 Female 136 lb 5/30/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 3/1/2006 Male 6/16/2006 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 5/4/2006 Male 6/22/2006 Physician United States
Primary
Concomitant
Tachycardia 2/2/2006 Male 180 lb 8/4/2006 Physician United States
Primary
Concomitant
Headache 12/1/2005 74 Female 8/4/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 7/13/2005 Female 8/4/2006 Other Health Professional United States
Primary
Concomitant
Injection Site Swelling 2/1/2006 81 Female 8/4/2006 Consumer United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 5/4/2006 Male 8/9/2006 Physician United States
Primary
Concomitant
Parvovirus B19 Serology Positive Other Serious 4/1/2005 Female 126 lb 10/2/2006 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 53 Male 10/18/2006 Physician United States
Primary
Concomitant
Dehydration Hospitalization 2/21/2006 72 Male 133 lb 11/29/2006 Consumer United States
Primary
Concomitant
Marrow Hyperplasia Other Serious 9/28/2005 Female 184 lb 12/18/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Male 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension 10/1/2005 78 Male 12/22/2006 Consumer United States
Primary
Concomitant
Malaise Female 12/22/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Male 12/22/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 3/16/2006 Female 12/22/2006 Other Health Professional United States
Primary
Concomitant
Nausea 1/1/2006 Female 12/22/2006 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 2/21/2006 72 Male 133 lb 12/21/2006 Consumer United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 9/28/2005 Female 184 lb 1/22/2007 Other Health Professional United States
Primary
Concomitant
Parvovirus B19 Serology Positive Other Serious 4/1/2005 Female 126 lb 1/23/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 2/27/2006 Male 127 lb 1/24/2007 Physician United States
Primary
Secondary
Concomitant
Marrow Hyperplasia Other Serious 9/28/2005 Female 184 lb 2/1/2007 Other Health Professional United States
Primary
Concomitant
Thrombosis Life Threatening 1/1/2006 Female 127 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Parvovirus B19 Serology Positive Other Serious 4/1/2005 Female 126 lb 2/15/2007 Physician United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 3/23/2007 Physician United States
Primary
Concomitant
Thrombosis Life Threatening 1/1/2006 Female 127 lb 3/27/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Transplant Other Serious 66 Male 240 lb 3/27/2007 Physician United States
Primary
Concomitant
Thrombosis Life Threatening 1/1/2006 Female 127 lb 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Penile Pain Hospitalization 3/18/2007 Male 182 lb 4/6/2007 Physician United States
Primary
Secondary
Concomitant
Penile Pain Hospitalization 3/18/2007 Male 182 lb 4/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious Male 5/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Amnesia Other Serious Male 220 lb 5/31/2007 Physician United States
Primary
Concomitant
Nausea 10/1/2006 Female 171 lb 6/26/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/12/2006 Male 6/26/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 1/1/2006 Male 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased 1/1/2006 83 Male 6/26/2007 Physician United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Myalgia 11/1/2006 Male 6/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 4/30/2007 Female 106 lb 7/3/2007 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/30/2007 Female 106 lb 7/23/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 4/30/2007 Female 106 lb 7/27/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2007 Male 8/3/2007 Physician United States
Primary
Concomitant
Wheezing Required Intervention 2/21/2006 72 Male 133 lb 8/10/2007 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 1/1/2007 Male 9/7/2007 Physician France
Primary
Concomitant
Pain In Extremity Other Serious 9/8/2007 Female 9/28/2007 Consumer United States
Primary
Concomitant
Premature Baby Other Serious 21 Female 11/7/2007 Physician United Kingdom
Primary
Concomitant
Parvovirus B19 Serology Positive Other Serious 4/1/2005 Female 126 lb 11/14/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/22/2005 Male 165 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 5/1/2007 Female 12/15/2007 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Deficiency 8/20/2002 Female 130 lb 12/15/2007 Physician United States
Primary
Concomitant
Incorrect Route Of Drug Administration 4/18/2007 Male 172 lb 12/15/2007 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased 5/1/2007 Female 12/15/2007 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Deficiency 9/17/2004 Male 12/15/2007 Physician United States
Primary
Concomitant
Blood Cholesterol Increased Female 12/15/2007 Consumer United States
Primary
Concomitant
Premature Labour Hospitalization 9/3/2007 Female 106 lb 1/24/2008 Physician Portugal
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 1/1/2007 Male 149 lb 1/25/2008 Physician
Primary
Secondary
Concomitant
Rectal Haemorrhage Life Threatening 11/30/2006 78 Male 1/25/2008 Other Health Professional United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 1/1/2007 Male 149 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/1/2006 Male 1/31/2008 Pharmacist Canada
Primary
Concomitant
Urticaria Other Serious 10/2/2007 Female 185 lb 2/6/2008 Other Health Professional United States
Primary
Concomitant
Hypovolaemia Hospitalization 1/25/2008 55 Male 123 lb 2/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance 12/26/2007 66 Female 126 lb 2/16/2008 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 1/1/2007 Male 149 lb 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 1/25/2008 55 Male 126 lb 2/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance 12/26/2007 66 Female 126 lb 2/27/2008 Other Health Professional United States
Primary
Concomitant
Red Blood Cell Acanthocytes Present Life Threatening 11/30/2006 78 Male 2/26/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 11/30/2006 78 Male 2/28/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2007 31 Female 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 3/17/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2008 60 Female 3/27/2008 Physician Canada
Primary
Secondary
Concomitant
Nausea Required Intervention 1/19/2008 97 Male 150 lb 4/4/2008 Other Health Professional United States
Primary
Concomitant
Wound Life Threatening 11/30/2006 78 Male 4/15/2008 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 11/30/2006 78 Male 4/15/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/30/2007 47 Female 4/18/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2008 60 Female 5/12/2008 Physician Canada
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Hospitalization 3/3/2006 Female 207 lb 5/20/2008 United States
Primary
Concomitant
Subileus Other Serious 1/1/2008 Male 5/23/2008 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Subileus Other Serious 1/1/2008 Male 5/28/2008 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2002 Female 6/10/2008 Other Health Professional
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 Female 175 lb 6/18/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2007 Male 167 lb 6/23/2008 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency 9/1/2007 Male 162 lb 6/23/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 Female 175 lb 7/10/2008 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 12/1/2005 Male 138 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 12/1/2005 Male 138 lb 7/29/2008 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 6/29/2005 Male 165 lb 8/5/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2008 60 Female 8/13/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/7/2008 60 Female 8/14/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 8/28/2008 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 10/9/2008 Consumer Spain
Primary
Concomitant
Cholecystitis Other Serious 10/6/2008 75 Female 10/29/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 10/30/2008 Consumer Spain
Primary
Concomitant
Drug Ineffective Other Serious 11/4/2008 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 4/1/2008 Male 11/4/2008 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 10/6/2008 75 Female 11/7/2008 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Other Serious 10/6/2008 75 Female 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 12/6/2008 Male 173 lb 12/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 12/23/2008 Physician Spain
Primary
Concomitant
Hallucination Hospitalization 12/6/2008 Male 173 lb 12/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 12/30/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 1/28/2009 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 1/30/2009 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/7/2008 Male 200 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 8/7/2008 Male 2/26/2009 Consumer United States
Primary
Concomitant
Malaise Other Serious 2/6/2009 Female 3/13/2009 Consumer United States
Primary
Concomitant
Lung Cancer Metastatic Death 1/16/2009 Male 120 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/7/2009 Male 200 lb 3/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2008 Female 4/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 2/6/2009 Female 4/28/2009 Consumer United States
Primary
Concomitant
Premature Labour Other Serious 21 Female 4/29/2009 Physician United Kingdom
Primary
Concomitant
Rectal Haemorrhage 9/25/2008 5/4/2009 Physician United States
Primary
Concomitant
Reticulocyte Count Decreased Other Serious Male 5/7/2009 Physician United States
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Other Serious Male 182 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Rectal Haemorrhage 9/25/2008 Female 5/23/2009 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/7/2009 Male 200 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 6/11/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/6/2009 Male 6/11/2009 Consumer United States
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Other Serious Male 182 lb 6/24/2009 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 5/1/2009 Female 6/26/2009 Other Health Professional United States
Primary
Concomitant
Skin Infection Other Serious 6/3/2009 Male 7/1/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/8/2009 Physician Spain
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 5/9/2009 Male 153 lb 7/7/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 7/17/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/1/2008 81 Female 7/24/2009 Physician Spain
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/8/2009 Female 7/27/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/1/2009 Female 7/27/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/6/2009 Male 7/30/2009 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 5/1/2009 Female 7/29/2009 Physician United States
Primary
Concomitant
Tachycardia Other Serious 8/7/2008 Male 8/11/2009 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 5/20/2009 Male 8/13/2009 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 6/8/2009 Male 164 lb 8/13/2009 Physician Germany
Primary
Concomitant
Haemoglobin Decreased Other Serious 8/5/2009 Male 143 lb 8/20/2009 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 6/8/2009 Male 164 lb 8/24/2009 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 5/1/2009 62 Female 172 lb 9/2/2009 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 7/11/2008 Male 161 lb 9/4/2009 Consumer United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 6/8/2009 Male 164 lb 9/9/2009 Physician Germany
Primary
Concomitant
Vision Blurred 4/1/2009 Female 9/16/2009 Consumer United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 6/8/2009 Male 164 lb 9/18/2009 Physician Germany
Primary
Concomitant
Reticulocyte Count Abnormal Hospitalization 7/3/2009 Male 276 lb 9/28/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/19/2009 51 Female 223 lb 10/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data