Aranesp combined with Metoprolol

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Asthenia Hospitalization 7/9/2005 68 Female 196 lb 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 62 Female 205 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Hospitalization 2/1/2006 Male 2/24/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Hospitalization 6/1/2004 Female 126 lb 3/6/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/10/2006 Male 154 lb 3/6/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/23/2005 Male 111 lb 3/7/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 2/10/2006 Male 154 lb 3/21/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/23/2005 Male 111 lb 3/27/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Male 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 6/19/2005 41 Male 4/10/2006 Physician Denmark
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Male 4/13/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 6/1/2004 Female 126 lb 4/14/2006 Physician United States
Primary
Concomitant
Tongue Injury Hospitalization 6/19/2005 41 Male 4/18/2006 Physician Denmark
Primary
Concomitant
Therapeutic Response Decreased Other Serious 10/1/2002 Female 141 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 4/1/2006 Male 5/31/2006 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious 5/30/2006 89 Male 176 lb 7/10/2006 Physician United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 7/17/2006 Female 8/1/2006 Physician Australia
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 7/14/2006 Female 214 lb 8/2/2006 Physician United States
Primary
Concomitant
Bladder Spasm Hospitalization 8/1/2006 79 Male 10/2/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/20/2006 62 Female 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Male 167 lb 9/24/2007 Pharmacist United States
Primary
Concomitant
Muscular Weakness Hospitalization 7/9/2005 68 Female 196 lb 9/25/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 10/16/2007 Physician Australia
Primary
Concomitant
Liver Function Test Abnormal Other Serious 70 Male 10/18/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Reticulocyte Count Decreased Other Serious 5/3/2007 Male 190 lb 10/29/2007 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 9/23/2005 Male 111 lb 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased 1/1/2007 Female 12/15/2007 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization Female 1/3/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 61 Male 6/13/2008 Consumer Canada
Primary
Concomitant
Toxic Encephalopathy Life Threatening 5/18/2008 92 Male 171 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/23/2005 Male 111 lb 6/23/2008 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity 4/20/2008 Female 6/23/2008 Consumer
Primary
Concomitant
Skin Haemorrhage 1/1/2008 Male 6/23/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 2/1/2008 65 Female 6/23/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 9/23/2005 Male 111 lb 7/16/2008 Physician United States
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 6/1/2008 Female 165 lb 8/4/2008 United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 8/5/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/1/2008 63 Male 9/26/2008 Physician Canada
Primary
Secondary
Concomitant
Iron Deficiency Other Serious 1/1/2007 Male 110 lb 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Diplopia 6/19/2008 Female 12/16/2008 Consumer United States
Primary
Concomitant
Pyrexia 7/3/2008 Female 12/16/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2007 Male 110 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious Male 12/31/2008 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Male 1/26/2009 Physician United States
Primary
Concomitant
Myocardial Ischaemia Disability 12/30/2008 Female 2/2/2009 Other Health Professional Italy
Primary
Concomitant
Vitamin B12 Deficiency Other Serious 6/1/2007 Male 219 lb 2/11/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 78 Female 340 lb 2/24/2009 Lawyer United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 2/12/2009 Male 177 lb 2/27/2009 Physician Germany
Primary
Secondary
Concomitant
Skin Turgor Decreased Other Serious Female 143 lb 3/9/2009 Lawyer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 1/31/2007 67 Female 181 lb 3/23/2009 Lawyer United States
Primary
Concomitant
Parathyroid Tumour Benign Other Serious 12/16/2008 53 Male 4/2/2009 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/1/2006 Female 109 lb 4/6/2009 Physician United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 12/30/2006 71 Male 4/13/2009 Other Health Professional United States
Primary
Concomitant
Parathyroid Tumour Benign Other Serious 12/16/2008 53 Male 4/28/2009 Physician Germany
Primary
Secondary
Concomitant
Skin Warm Death 10/7/2007 56 Female 5/15/2009 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/16/2009 Male 152 lb 5/18/2009 Physician Switzerland
Primary
Concomitant
Skin Warm Death 10/7/2007 56 Female 5/18/2009 Lawyer United States
Primary
Secondary
Concomitant
Stent Occlusion Other Serious 1/1/2008 Female 145 lb 5/19/2009 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 4/16/2009 Male 152 lb 5/19/2009 Physician Switzerland
Primary
Concomitant
Syncope Hospitalization 2/23/2009 45 Male 5/21/2009 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 58 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 2/12/2009 Male 177 lb 7/9/2009 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 7/17/2009 Physician United States
Primary
Concomitant
Haptoglobin Decreased Hospitalization 1/1/2009 Male 207 lb 8/11/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2009 Male 207 lb 8/28/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/1/2009 Male 207 lb 9/25/2009 Consumer United States
Primary
Concomitant
Reticulocyte Count Abnormal Hospitalization 7/3/2009 Male 276 lb 9/28/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 9/28/2009 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 10/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Pyrexia Hospitalization 9/4/2009 Female 163 lb 10/5/2009 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/19/2009 51 Female 223 lb 10/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/1/2009 Male 207 lb 10/16/2009 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 4/1/2006 65 Male 209 lb 10/22/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2009 83 Female 128 lb 11/2/2009 Consumer United States
Primary
Secondary
Concomitant
Skin Induration Other Serious 8/1/2004 48 Male 161 lb 11/9/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/19/2009 Female 162 lb 11/11/2009 Physician Australia
Primary
Concomitant
Vomiting Hospitalization 10/19/2009 Female 162 lb 11/16/2009 Physician Australia
Primary
Concomitant
Blood Glucose Fluctuation Hospitalization 71 Male 11/23/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/1/2009 Male 207 lb 11/30/2009 Consumer United States
Primary
Concomitant
Transplant Failure Other Serious 5/8/2009 Male 155 lb 12/1/2009 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Other Serious Female 188 lb 12/1/2009 Other Health Professional Ireland
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 58 Male 12/1/2009 Physician United States
Primary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/4/2009 Physician Germany
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 11/22/2009 Male 12/4/2009 Physician United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2005 59 Male 12/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 11/4/2009 46 Female 161 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2005 59 Male 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 8/25/2009 68 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Peritonitis Other Serious 5/5/2009 35 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 1/1/2009 Male 155 lb 12/14/2009 Physician Germany
Primary
Concomitant
Peritonitis Bacterial Other Serious 1/5/2009 69 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Skin Tightness Other Serious 1/1/2005 59 Male 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Aplastic Anaemia Life Threatening 9/28/2009 Male 1/14/2010 Physician Netherlands
Primary
Concomitant
Vomiting Other Serious Female 1/15/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious Female 1/20/2010 United States
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 11/12/2009 Male 1/25/2010 United States
Primary
Concomitant
Intermittent Claudication Other Serious 7/10/2009 64 Male 164 lb 1/29/2010 Physician Netherlands
Primary
Concomitant
Neutropenia Hospitalization 11/4/2009 Female 1/29/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 3/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 7/1/2002 Female 142 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 3/1/2008 Male 3/26/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious Female 188 lb 3/26/2010 Other Health Professional Ireland
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 Male 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/1/2008 Female 176 lb 3/29/2010 Consumer Netherlands
Primary
Concomitant
Death Death Female 106 lb 3/30/2010 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 3/31/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 4/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 Male 4/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2005 Male 4/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 9/1/2007 77 Male 183 lb 5/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/25/2009 59 Male 106 lb 5/6/2010 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious Female 188 lb 5/6/2010 Other Health Professional Ireland
Primary
Concomitant
Vomiting Other Serious 10/25/2009 59 Male 108 lb 5/25/2010 United States
Primary
Secondary
Concomitant
Osteopenia Other Serious 2/1/2010 47 Female 128 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 300 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 9/1/2009 83 Male 168 lb 6/17/2010 Physician Germany
Primary
Concomitant
Vomiting Other Serious 1/1/2008 74 Female 6/17/2010 Other Health Professional United States
Primary
Concomitant
Osteopenia Other Serious 2/1/2010 47 Female 128 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/19/2009 51 Female 223 lb 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 6/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Angiodysplasia Haemorrhagic Other Serious 1/1/2009 82 Male 168 lb 6/30/2010 Physician Germany
Primary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 7/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Soft Tissue Inflammation Other Serious Female 7/8/2010 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2008 86 Male 126 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 81 Male 7/20/2010 Other Health Professional Australia
Primary
Concomitant
Skin Plaque Other Serious Female 231 lb 7/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Viith Nerve Paralysis Other Serious 9/1/2007 77 Male 183 lb 7/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 7/22/2010 United States
Primary
Concomitant
Soft Tissue Inflammation Other Serious Female 7/26/2010 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 2/1/2010 86 Male 145 lb 8/2/2010 Physician United States
Primary
Secondary
Concomitant
Yawning Other Serious 1/1/1998 80 Female 8/2/2010 Lawyer United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 8/28/2006 66 Female 8/3/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 2/3/2009 72 Male 203 lb 8/5/2010 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 8/6/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2002 63 Male 140 lb 8/26/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Analysis Abnormal Other Serious 8/28/2006 66 Female 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/23/2009 63 Female 9/21/2010 Physician United States
Primary
Concomitant
Urine Analysis Abnormal Other Serious 8/28/2006 66 Female 10/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 1/1/2009 79 Male 124 lb 10/5/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 46 Male 218 lb 10/15/2010 Lawyer United States
Primary
Concomitant
Renal Impairment Hospitalization 2/15/2009 63 Female 148 lb 10/18/2010 Physician Sweden
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 7/1/2002 59 Female 142 lb 10/20/2010 United States
Primary
Secondary
Concomitant
Tendon Pain Other Serious 1/1/2000 49 Female 121 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant