Ara-C combined with Cyclophosphamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Hypertrophy Life Threatening 3/27/2006 Female 116 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/20/2006 70 Female 117 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 5/26/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 3/27/2006 Female 116 lb 6/9/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 4/7/2006 Female 116 lb 8/10/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 7/16/2006 57 Male 198 lb 9/5/2006 United Kingdom
Primary
Concomitant
Pyrexia Other Serious 9/11/2006 35 Male 154 lb 9/19/2006 Physician France
Primary
Secondary
Viral Infection Other Serious 45 Female 9/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/11/2006 35 Male 154 lb 9/19/2006 Physician France
Primary
Secondary
Fungal Infection Death 10/2/2006 Physician United States
Primary
Concomitant
Mucormycosis Death 10/2/2006 Physician United States
Primary
Concomitant
Mucormycosis Death 10/13/2006 Physician United States
Primary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 10/30/2006 Other Health Professional United States
Primary
Concomitant
Hospitalisation Other Serious 1/19/2006 Female 179 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 Female 179 lb 12/12/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 12/6/2006 Other Health Professional Norway
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Pyrexia Other Serious 12/1/2004 49 Male 2/8/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 12/1/2004 49 Male 2/10/2007 Japan
Primary
Concomitant
Somnolence Other Serious 6/6/2005 40 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Musculoskeletal Disorder Hospitalization 6/16/2008 7/28/2008 Physician Italy
Primary
Secondary
Sepsis Other Serious 1/1/2008 Male 7/30/2008 Physician United Kingdom
Primary
Secondary
Musculoskeletal Disorder Hospitalization 6/16/2008 8/4/2008 Physician Italy
Primary
Secondary
Peripheral Sensory Neuropathy Hospitalization 6/1/2008 61 Female 8/8/2008 Physician Italy
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Stem Cell Transplant Disability 39 Female 8/20/2008 Physician United States
Primary
Secondary
Septic Shock Hospitalization 8/26/2008 9/3/2008 Physician Italy
Primary
Secondary
Peripheral Sensory Neuropathy Hospitalization 6/16/2008 61 Female 9/8/2008 Physician Italy
Primary
Secondary
Thrombotic Microangiopathy Other Serious 23 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 10/24/2008 Physician Italy
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 8/1/2006 24 Male 10/28/2008 Consumer Poland
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 11/3/2008 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Other Serious 45 Male 12/2/2008
Primary
Secondary
Orchidectomy Hospitalization 1 Male 12/4/2008 Other Health Professional Japan
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 12/8/2008 Physician Italy
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 10/1/2004 69 Female 12/16/2008 Consumer United Kingdom
Primary
Secondary
Sepsis Life Threatening Male 1/12/2009 Other Health Professional United States
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 12/21/2008 4 Male 44 lb 1/7/2009 Physician Germany
Primary
Secondary
Concomitant
Puncture Site Infection Hospitalization 12/21/2008 4 Male 44 lb 1/22/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 14 Male 64 lb 2/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 2/2/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/1/2008 75 Female 4/3/2009 Physician Italy
Primary
Secondary
Graft Versus Host Disease Other Serious 17 Male 4/15/2009 Other Health Professional India
Primary
Secondary
Concomitant
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/21/2008 4 Male 44 lb 6/26/2009 Physician Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/1/2007 Female 7/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 57 Male 8/6/2009
Primary
Secondary
Concomitant
Visual Impairment Other Serious 42 Female 137 lb 8/10/2009 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 29 Male 10/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 74 Female 10/26/2009 Other Health Professional Japan
Primary
Secondary
Thrombotic Microangiopathy Other Serious 1/1/2005 47 Male 10/30/2009 Japan
Primary
Concomitant
Weight Decreased Other Serious 6/1/2001 61 Male 11/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 42 Male 12/11/2009 Consumer United Kingdom
Primary
Secondary
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 12/8/2009 29 Female 1/13/2010 Physician Italy
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 8/1/2007 14 Male 64 lb 2/5/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/12/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/17/2010 Physician Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 3/19/2010 Physician Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/29/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious Male 3/19/2010 United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/31/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 4/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Hypertension Hospitalization 10/4/2008 67 Female 4/13/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/13/2010 Physician United States
Primary
Secondary
Mesenteric Vein Thrombosis Other Serious 4/10/2008 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 6/16/2008 61 Female 4/13/2010 Physician United States
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/14/2008 4/13/2010 Physician United States
Primary
Secondary
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 8/26/2008 4/20/2010 Physician United States
Primary
Secondary
Wernicke's Encephalopathy Disability 5/9/2008 4/20/2010 Physician United States
Primary
Secondary
Intestinal Haemorrhage Hospitalization 3/14/2008 4/20/2010 Physician United States
Primary
Secondary
T-cell Lymphoma Hospitalization 11/30/2008 70 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Life Threatening 10/6/2008 55 Male 4/27/2010 Physician United States
Primary
Secondary
Concomitant
T-cell Lymphoma Hospitalization 5/9/2008 4/30/2010 Physician United States
Primary
Secondary
Intracranial Hypotension Hospitalization 2/23/2010 51 Male 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/10/2010 34 Female 6/4/2010 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 5/10/2010 34 Female 6/8/2010 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 5/10/2010 34 Female 6/15/2010 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/18/2010 76 Male 216 lb 8/5/2010 Physician United States
Primary
Concomitant
Interacting
Urinary Bladder Haemorrhage Hospitalization 4/30/2009 55 Male 8/6/2010 Physician Italy
Primary
Secondary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 4/30/2009 55 Male 8/18/2010 Physician Italy
Primary
Secondary
Concomitant
Toothache Hospitalization 3/23/2008 19 Female 143 lb 9/28/2010 Consumer
Primary
Secondary
Concomitant
Paraparesis Hospitalization 9/1/2009 65 Male 10/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 31 Female 10/15/2010 Other Health Professional United States
Primary
Secondary
Somnolence Hospitalization 6/16/2010 61 Male 10/21/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 12/12/2006 64 Female 154 lb 11/9/2010 Physician Germany
Primary
Concomitant
Neurotoxicity Hospitalization 7/1/2007 70 Female 150 lb 11/9/2010 Physician Germany
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Transplant Failure Other Serious 9 Female 2/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease Other Serious Female 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Other Serious 12 2/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/19/2011 9 Female 66 lb 2/16/2011 Physician Netherlands
Primary
Concomitant
Renal Impairment Other Serious 17 Male 2/17/2011 Physician United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2011 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/28/2011 Other Health Professional United Kingdom
Primary
Secondary
Cytomegalovirus Infection Hospitalization 4/30/2009 55 Male 3/1/2011 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 3/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 11/15/2010 9 Female 66 lb 3/7/2011 Physician Netherlands
Primary
Concomitant
Neutropenia Other Serious 17 Male 3/7/2011 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Other Serious 17 Male 3/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 17 Male 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 1/20/2011 60 Female 134 lb 4/5/2011 Physician United Kingdom
Primary
Secondary
Dyspnoea Other Serious 4/14/2011 Physician United Kingdom
Primary
Secondary
Leukaemia Recurrent Death 10/12/2011 2 Male 30 lb 10/16/2012 Physician De
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/9/2012 9/6/2012 Physician Us
Primary
Secondary
Viral Pharyngitis Other Serious 12/2005 Male 9/7/2012 Lawyer Us
Primary
Concomitant
Multi-organ Failure Death 2012 Female 171 lb 11/12/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Skin Infection Hospitalization 2012 10 Female 99 lb 12/20/2012 Consumer Us
Primary
Secondary
Concomitant
Death Death Female 10/3/2012 Physician Us
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 2012 14 Male 169 lb 11/13/2012 Consumer Us
Primary
Secondary
Exposure During Pregnancy Other Serious Female 11/5/2012 Physician Mx
Primary
Secondary
Off Label Use Life Threatening 9/21/2012 2 Male 23 lb 11/20/2012 Consumer De
Primary
Secondary
Off Label Use Other Serious 9/21/2012 2 Male 23 lb 8/16/2013 Other Health Professional De
Primary
Secondary
Urinary Tract Infection Death Female 11/6/2012 Physician Mx
Primary
Secondary
Underweight Congenital Anomaly 11/2/2012 Other Health Professional Mx
Primary
Secondary
Septic Shock Death 67 Female 11/14/2012 Country Not Specified
Primary
Concomitant
Neutropenia Other Serious NotSpecified 1/25/2013 Physician Country Not Specified
Primary
Secondary
Sepsis Hospitalization 11/22/2012 0 Male 16 lb 12/3/2012 Physician Us
Primary
Secondary
Ventricular Tachycardia Hospitalization 4/22/2012 10 Male 77 lb 1/28/2013 Consumer Us
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/22/2012 13 Male 12/21/2012 Physician Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/30/2012 4 Male 2/20/2013 Physician Us
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 12/12/2012 11 Male 2/20/2013 Physician Us
Primary
Secondary
Concomitant
Infection Death NotSpecified 1/30/2013 Physician It
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 12/30/2012 4 Male 2/24/2013 Physician Us
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/22/2013 7 Male 8/28/2013 Other Health Professional Ca
Primary
Secondary
Vomiting Other Serious NotSpecified 4/22/2013 Physician Fr
Primary
Secondary
Treatment Failure Other Serious NotSpecified 5/13/2013 Other Health Professional Us
Primary
Secondary
Enterococcal Bacteraemia Other Serious 60 Male 6/6/2013 Physician Us
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 7/2/2013 Physician Gb
Primary
Secondary
Concomitant
Tonic Clonic Movements Hospitalization 10 Male 7/3/2013 Other Health Professional Cn
Primary
Secondary

Drug Data