Apidra combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
No Adverse Drug Effect 8/1/2006 72 Female 168 lb 10/23/2006 United States
Primary
Secondary
Concomitant
Blood Glucose Increased 8/2/2006 73 Female 200 lb 10/16/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 3/5/2007 Consumer United Kingdom
Primary
Concomitant
No Adverse Drug Effect 8/1/2006 72 Female 168 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 12/13/2006 70 Female 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 7/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 1/1/2006 70 Female 168 lb 7/26/2007 United States
Primary
Secondary
Concomitant
Cardiac Failure Death 4/4/2006 76 Male 192 lb 11/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 1/1/2006 70 Female 168 lb 10/22/2007 Physician United States
Primary
Secondary
Concomitant
Somnolence 61 Female 132 lb 10/22/2007 United States
Primary
Concomitant
Blood Pressure Increased 9/1/2007 64 Male 10/22/2007 United States
Primary
Concomitant
Visual Disturbance 66 Female 10/22/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 53 Female 12/13/2007 South Africa
Primary
Secondary
Concomitant
Oedema Peripheral 8/23/2007 58 Female 10/8/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2006 63 Male 12/26/2007 Consumer United States
Primary
Concomitant
Muscle Spasms Other Serious 12/13/2006 70 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Overdose Other Serious 8/2/2007 48 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2008 59 Male 7/8/2008 Other Health Professional France
Primary
Concomitant
Vision Blurred 1/1/2007 45 Female 200 lb 7/7/2008 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 7/3/2008 56 Male 206 lb 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Disability 1/1/2007 28 Female 243 lb 9/3/2008 Physician Germany
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2008 59 Male 9/12/2008 Other Health Professional France
Primary
Concomitant
Pharmaceutical Product Complaint 61 Female 9/23/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2008 59 Male 10/9/2008 Other Health Professional France
Primary
Concomitant
Muscle Rupture Other Serious 8/28/2008 59 Male 10/9/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/9/2008 69 Female 230 lb 11/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/9/2008 69 Female 230 lb 11/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2008 58 Male 205 lb 1/27/2009 Physician France
Primary
Concomitant
Wrong Drug Administered Other Serious 1/23/2007 61 Male 262 lb 2/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 4/28/2007 61 Male 246 lb 2/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 2/26/2009 57 Female 4/1/2009 Physician Indonesia
Primary
Concomitant
Atrial Fibrillation Other Serious 3/30/2009 62 Male 4/9/2009 Consumer Australia
Primary
Secondary
Concomitant
Sciatica Hospitalization 12/1/2008 Male 345 lb 4/17/2009 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Other Serious 41 Female 6/23/2009 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/21/2009 59 Male 8/12/2009 Consumer United States
Primary
Secondary
Sensory Loss Other Serious 2/11/2009 Female 232 lb 9/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2009 53 Male 154 lb 10/27/2009 Consumer Brazil
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 1/1/2006 55 Male 11/10/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 11/14/2009 63 Male 1/25/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/14/2009 64 Male 1/26/2010 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/14/2009 64 Male 2/1/2010 Physician France
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 10/5/2009 55 Male 239 lb 1/27/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 11/14/2009 63 Male 2/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/14/2009 64 Male 2/5/2010 Physician France
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased 58 Male 181 lb 2/23/2010 Physician United States
Primary
Secondary
Myocardial Infarction Hospitalization 3/2/2010 59 Female 159 lb 3/18/2010 Consumer Colombia
Primary
Concomitant
Anaphylactic Reaction Life Threatening 4/22/2010 70 Female 208 lb 5/21/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Hospitalization 6/10/2009 54 Male 5/21/2010 Physician
Primary
Secondary
Concomitant
Memory Impairment Other Serious 4/1/2010 Female 7/7/2010 Pharmacist Brazil
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/1/2009 78 Female 7/15/2010 Physician Australia
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 6/1/2010 66 Male 218 lb 8/9/2010 Physician United Kingdom
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 5/19/2010 30 Male 11/22/2010 Physician Slovenia
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2007 57 Female 1/7/2011 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/6/2010 64 Female 1/12/2011 Physician France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/6/2010 63 Female 1/17/2011 Other Health Professional France
Primary
Secondary
Hypersensitivity Other Serious 12/28/2010 Male 280 lb 2/3/2011 Other Health Professional United States
Primary
Concomitant
Renal Disorder 71 Female 2/24/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Iron Decreased 4/1/2010 65 Male 2/24/2011 United States
Primary
Secondary
Concomitant
Diarrhoea 4/1/2010 65 Male 2/25/2011 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/20/2011 67 Male 3/15/2011 Physician United States
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/1/2007 57 Female 4/8/2011 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Hospitalization 1/20/2011 67 Male 4/6/2011 Physician United States
Primary
Secondary
Concomitant
Adverse Event Hospitalization Male 231 lb 4/18/2011 Physician Japan
Primary
Concomitant
Death Death 7/25/2010 80 Male 161 lb 4/18/2011 Physician Japan
Primary
Concomitant
Blood Iron Decreased 4/1/2010 65 Male 5/4/2011 Consumer United States
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 11/1/2009 39 Female 197 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 1/1/2005 51 Male 207 lb 5/17/2011 Consumer Brazil
Primary
Concomitant
Drug Ineffective Other Serious 1/1/2005 51 Male 207 lb 5/19/2011 Consumer Brazil
Primary
Concomitant
Coronary Artery Disease Hospitalization 1/1/2007 57 Female 5/20/2011 Other Health Professional United States
Primary
Concomitant
Retinal Haemorrhage Hospitalization 31 Male 231 lb 5/23/2011 Physician Japan
Primary
Concomitant
Hepatitis Required Intervention 1/1/2011 48 Male 180 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Headache Hospitalization 1/1/2007 57 Female 6/14/2011 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/11/2011 64 Female 167 lb 6/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/7/2011 64 Female 6/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/7/2011 64 Female 7/4/2011 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious Female 7/8/2011 United States
Primary
Concomitant
No Adverse Event 31 Male 231 lb 7/11/2011 Physician Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 6/16/2011 61 Female 130 lb 7/15/2011 Physician Japan
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 6/16/2011 61 Female 130 lb 7/25/2011 Consumer Japan
Primary
Concomitant
Pancreatitis Hospitalization 6/7/2011 64 Female 7/26/2011 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/7/2011 64 Female 7/27/2011 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Male 295 lb 8/5/2011 Consumer United States
Primary
Concomitant
Hot Flush 1/1/2011 63 Female 200 lb 8/6/2011 Consumer United States
Primary
Concomitant
Diarrhoea 8/3/2011 69 Male 290 lb 8/22/2011 United States
Primary
Concomitant
Syncope Other Serious 7/28/2011 84 Female 110 lb 8/23/2011 Consumer Brazil
Primary
Secondary
Concomitant
Wrong Drug Administered Hospitalization 6/11/2011 64 Female 167 lb 8/23/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Death 1/1/2007 57 Female 9/22/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/8/2011 75 Male 9/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Macular Oedema Disability 2/17/2011 60 Female 10/5/2011 Physician Japan
Primary
Concomitant
Death Death Male 331 lb 10/24/2011 Pharmacist Australia
Primary
Concomitant
Thyroid Cancer Hospitalization 6/1/2010 51 Male 10/25/2011 Consumer Canada
Primary
Concomitant
Myalgia Other Serious Male 10/28/2011 Consumer United Kingdom
Primary
Concomitant
Thrombosis Hospitalization 8/1/2008 40 Female 280 lb 10/31/2011 Other Health Professional United States
Primary
Concomitant
Neoplasm Progression Other Serious 5/2/2011 75 Female 137 lb 11/2/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 1/1/2011 85 Female 112 lb 11/9/2011 Consumer Brazil
Primary
Concomitant
Interacting
Musculoskeletal Pain 2/1/2011 64 Female 11/11/2011 Consumer United States
Primary
Concomitant
Anti-insulin Antibody Positive Hospitalization 10/1/2010 11/17/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization 8/8/2011 75 Male 11/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 8/8/2011 75 Male 11/29/2011 Consumer United States
Primary
Secondary
Concomitant
Abdominal Pain Upper 8/3/2011 69 Male 290 lb 11/30/2011 United States
Primary
Concomitant
Condition Aggravated Disability 60 Female 220 lb 12/9/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Cardiac Tamponade Hospitalization 8/8/2011 75 Male 12/21/2011 Consumer United States
Primary
Secondary
Concomitant
Product Quality Issue 69 Female 12/20/2011 Consumer United States
Primary
Concomitant
Pruritus Other Serious 60 Female 220 lb 12/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 1/1/2011 71 Female 159 lb 12/30/2011 Consumer Brazil
Primary
Secondary
Concomitant
Pain Hospitalization 8/1/2008 40 Female 280 lb 1/3/2012 Consumer United States
Primary
Concomitant
Unevaluable Event 10/4/2011 53 Male 1/29/2012 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 8/1/2008 40 Female 280 lb 2/7/2012 Lawyer United States
Primary
Concomitant
Injection Site Abscess Hospitalization 1/6/2012 Male 2/6/2012 Consumer Germany
Primary
Concomitant
Adverse Event Hospitalization 79 Male 352 lb 2/9/2012 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2011 53 Male 2/10/2012 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Hospitalization 1/6/2012 47 Male 2/1/2012 Other Health Professional Germany
Primary
Concomitant
Bursitis Hospitalization 1/4/2012 72 Male 2/21/2012 Physician Germany
Primary
Concomitant
Blood Glucose Increased 1/4/2011 63 Female 2/24/2012 Consumer France
Primary
Secondary
Concomitant
Blood Glucose Increased 1/1/2011 Male 2/24/2012 Consumer United States
Primary
Secondary
Blood Glucose Increased 1/1/2011 66 Male 2/24/2012 Consumer United States
Primary
Secondary
Weight Increased 5/14/2011 45 Female 140 lb 2/27/2012 Consumer United States
Primary
Concomitant
Bursitis Hospitalization 1/4/2012 71 Male 198 lb 2/29/2012 Physician Germany
Primary
Concomitant
Renal Impairment Other Serious 1/27/2012 42 Male 3/7/2012 Consumer Germany
Primary
Concomitant
Blood Glucose Increased Other Serious 1/1/2011 53 Male 3/8/2012 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/27/2012 42 Male 3/12/2012 Physician Germany
Primary
Concomitant
Death Death 7/25/2010 80 Male 161 lb 3/29/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 1/1/2011 65 Female 174 lb 3/29/2012 Physician Germany
Primary
Concomitant
Lactic Acidosis Death 8/11/2011 80 Female 4/3/2012 Other Health Professional Germany
Primary
Concomitant
Bradycardia Hospitalization 8/12/2011 62 Male 4/4/2012 Physician United States
Primary
Concomitant
Confusional State Other Serious 5/29/2009 72 Female 245 lb 4/2/2012 Lawyer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 3/1/2012 80 Male 160 lb 4/16/2012 Consumer United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 8/12/2011 62 Male 4/17/2012 Physician United States
Primary
Concomitant
Mallory-weiss Syndrome Hospitalization 3/25/2012 71 Female 4/20/2012 Other Health Professional United States
Primary
Secondary
Rales Other Serious 54 Male 274 lb 4/30/2012 Consumer United States
Primary
Concomitant
Dizziness 4/20/2011 Female 5/1/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Decreased 4/1/2011 83 Female 5/1/2012 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased 6/8/2011 55 Male 260 lb 5/1/2012 Consumer United States
Primary
Secondary
Concomitant
Dizziness 55 Female 181 lb 5/1/2012 Pharmacist United States
Primary
Concomitant
Pain 1/1/2011 58 Female 5/1/2012 Consumer United States
Primary
Secondary
Concomitant
Headache Hospitalization 4/3/2012 28 Female 165 lb 4/27/2012 Consumer United States
Primary
Concomitant
Foot Fracture Other Serious 8/29/2011 50 Female 5/4/2012 Other Health Professional Germany
Primary
Concomitant
Blood Glucose Increased Other Serious 3/11/2012 80 Male 160 lb 5/10/2012 Consumer United States
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Hospitalization 8/12/2011 62 Male 5/15/2012 Physician United States
Primary
Concomitant
Insomnia Other Serious 8/3/2011 69 Male 290 lb 5/22/2012 United States
Primary
Concomitant
Angina Pectoris Hospitalization 8/12/2011 62 Male 5/24/2012 Physician United States
Primary
Concomitant
Malaise Disability 3/27/2012 74 Female 5/25/2012 Consumer United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 4/3/2012 28 Female 165 lb 6/13/2012 Consumer United States
Primary
Concomitant
Emphysema Other Serious 12/9/2011 66 Male 7/4/2012 Consumer Japan
Primary
Concomitant
Generalised Oedema 4/10/2012 74 Female 143 lb 7/12/2012 Physician Germany
Primary
Concomitant
Pancreatic Carcinoma Stage Iv Hospitalization 12/9/2011 66 Male 8/16/2012 Physician Japan
Primary
Concomitant
Mallory-weiss Syndrome Hospitalization 3/25/2012 71 Female 10/18/2012 Consumer Us
Primary
Secondary
Tendon Rupture Other Serious 5/1/2012 63 Male 1/25/2013 Consumer Fr
Primary
Secondary
Urinary Tract Infection Hospitalization 3/15/2013 57 Female 220 lb 6/4/2013 Physician Us
Primary
Secondary
Concomitant
Drug Hypersensitivity 53 Female 6/8/2013 Consumer Us
Primary
Secondary

Drug Data