Antihistamines combined with Fluorouracil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Maculo-papular Other Serious 44 Female 9/17/2008
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 44 Female 9/17/2008
Primary
Secondary
Concomitant
Oral Disorder Other Serious 7/30/2010 76 Female 77 lb 9/20/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Life Threatening 9/6/2010 68 Female 128 lb 10/6/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 63 Male 126 lb 10/7/2010 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 9/6/2010 68 Female 128 lb 10/13/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 8/13/2010 10/27/2010 Other Health Professional Japan
Primary
Concomitant
Necrotising Fasciitis Disability 9/21/2010 60 Male 126 lb 10/27/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 63 Male 126 lb 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 10/29/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Other Serious 7/13/2010 10/29/2010 Other Health Professional Japan
Primary
Concomitant
Hepatic Encephalopathy Death 6/25/2010 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 10/20/2010 11/12/2010 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 9/6/2010 68 Female 128 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 8/13/2010 11/19/2010 Physician Japan
Primary
Concomitant
Weight Decreased Disability 9/21/2010 11/24/2010 Physician Japan
Primary
Concomitant
Weight Decreased Disability 9/21/2010 60 Male 126 lb 11/25/2010 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 11/26/2010 Physician Japan
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/25/2010 11/30/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 11/4/2010 11/30/2010 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 9/23/2010 12/7/2010 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/12/2010 12/8/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/5/2010 12/10/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/30/2010 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/14/2010 12/16/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 9/15/2010 12/20/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 2/1/2009 12/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2010 12/21/2010 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2010 12/28/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Life Threatening 9/15/2010 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 7/2/2010 1/10/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 7/29/2010 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/7/2010 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Obstruction Death 8/5/2010 1/14/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/21/2010 1/18/2011 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 10/21/2010 71 Female 104 lb 1/24/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 8/14/2010 45 Female 119 lb 1/26/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 9/25/2010 64 Male 90 lb 1/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Life Threatening 10/1/2010 18 Male 106 lb 1/28/2011 Physician Japan
Primary
Concomitant
Pyelonephritis Hospitalization 11/4/2010 71 Male 126 lb 1/31/2011 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 10/20/2010 67 Male 139 lb 1/31/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 11/11/2010 51 Female 86 lb 2/1/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 2/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/30/2010 75 Female 117 lb 2/3/2011 Physician Japan
Primary
Concomitant
Paronychia Hospitalization 10/1/2010 18 Male 106 lb 2/4/2011 Physician Japan
Primary
Concomitant
Glossitis Other Serious 7/30/2010 76 Female 77 lb 2/4/2011 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 12/7/2010 67 Male 110 lb 2/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 10/1/2010 18 Male 106 lb 2/8/2011 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/15/2010 27 Male 101 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Acne Other Serious 7/5/2010 53 Male 139 lb 2/8/2011 Physician Japan
Primary
Concomitant
Metastases To Central Nervous System Hospitalization 8/30/2010 49 Male 143 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Hospitalization 7/2/2010 69 Male 154 lb 2/8/2011 Physician Japan
Primary
Concomitant
Infusion Related Reaction Life Threatening 8/9/2010 56 Male 154 lb 2/10/2011 Physician Japan
Primary
Concomitant
Dry Skin Hospitalization 11/4/2010 41 Female 99 lb 2/10/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 9/27/2010 80 Male 139 lb 2/10/2011 Other Health Professional Japan
Primary
Concomitant
Paronychia Death 8/27/2010 62 Male 132 lb 2/11/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/14/2010 68 Male 130 lb 2/11/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 10/18/2010 58 Male 165 lb 2/15/2011 Japan
Primary
Secondary
Concomitant
Duodenal Obstruction Hospitalization 8/5/2010 52 Male 134 lb 2/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/28/2010 72 Male 119 lb 2/21/2011 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 11/11/2010 58 Male 121 lb 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Hypocalcaemia Hospitalization 8/14/2010 45 Female 119 lb 2/23/2011 Pharmacist Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 9/1/2010 62 Male 126 lb 2/23/2011 Physician Japan
Primary
Concomitant
Jaundice Other Serious 9/30/2010 64 Male 176 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/11/2010 51 Female 86 lb 2/28/2011 Physician Japan
Primary
Secondary
Concomitant
Cystitis Hospitalization 10/10/2010 61 Female 121 lb 3/2/2011 Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 8/13/2010 55 Male 126 lb 3/7/2011 Other Health Professional Japan
Primary
Concomitant
Paronychia Other Serious 7/29/2010 63 Male 150 lb 3/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/28/2010 72 Male 119 lb 3/9/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Other Serious 8/31/2010 67 Male 143 lb 3/9/2011 Other Health Professional Japan
Primary
Concomitant
Alopecia Hospitalization 8/2/2010 40 Male 190 lb 3/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 8/30/2010 49 Male 143 lb 3/11/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 11/11/2010 75 Male 128 lb 3/16/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Potassium Decreased Hospitalization 8/30/2010 75 Female 117 lb 3/18/2011 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 2/2/2011 61 Female 176 lb 3/21/2011 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/11/2010 51 Female 86 lb 3/24/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 9/9/2010 81 Female 95 lb 3/28/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 7/29/2010 62 Male 126 lb 3/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/15/2010 47 Male 132 lb 3/29/2011 Physician Japan
Primary
Concomitant
Paronychia Death 8/27/2010 62 Male 132 lb 3/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 9/30/2010 64 Male 176 lb 3/31/2011 Other Health Professional Japan
Primary
Concomitant
Skin Fissures Hospitalization 11/4/2010 41 Female 99 lb 4/1/2011 Physician Japan
Primary
Secondary
Concomitant
Cheilitis Hospitalization 8/13/2010 55 Male 126 lb 4/1/2011 Other Health Professional Japan
Primary
Concomitant
Colorectal Cancer Hospitalization 10/1/2010 18 Male 106 lb 4/5/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Hospitalization 9/9/2010 81 Female 95 lb 4/6/2011 Physician Japan
Primary
Secondary
Concomitant
Paronychia Life Threatening 10/1/2010 18 Male 106 lb 4/6/2011 Other Health Professional Japan
Primary
Concomitant
Jaundice Death 7/1/2010 46 Male 146 lb 4/8/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 12/8/2010 56 Male 128 lb 4/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastases To Central Nervous System Hospitalization 8/30/2010 49 Male 143 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 12/8/2010 56 Male 128 lb 4/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/10/2010 61 Female 121 lb 4/11/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 11/11/2010 75 Male 128 lb 4/11/2011 Physician Japan
Primary
Secondary
Concomitant
Jaundice Death 7/1/2010 46 Male 146 lb 4/11/2011 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 10/23/2010 60 Male 132 lb 4/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Death 11/2/2010 56 Male 240 lb 4/13/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Death 10/18/2010 58 Male 165 lb 4/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 8/31/2010 40 Male 190 lb 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Diarrhoea Death 11/1/2010 71 Male 146 lb 4/20/2011 Physician Germany
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 7/29/2010 63 Male 150 lb 4/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Life Threatening 9/14/2010 78 Male 137 lb 4/25/2011 Physician Japan
Primary
Concomitant
Dermatitis Death 10/14/2010 68 Male 130 lb 4/25/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Sodium Increased Other Serious 7/29/2010 62 Male 126 lb 4/27/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/28/2010 72 Male 119 lb 4/27/2011 Physician Japan
Primary
Concomitant
Conjunctivitis Other Serious 8/31/2010 67 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Colorectal Cancer Death 9/30/2010 64 Male 176 lb 4/29/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/8/2010 56 Male 128 lb 5/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/29/2010 73 Male 119 lb 5/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 9/15/2010 76 Male 101 lb 5/5/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 11/11/2010 75 Male 128 lb 5/6/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/10/2010 61 Male 123 lb 5/11/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Fissures Hospitalization 11/4/2010 41 Female 99 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/11/2010 78 Male 130 lb 5/17/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/7/2010 62 Male 95 lb 5/19/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Death 11/2/2010 56 Male 240 lb 5/19/2011 Other Health Professional Japan
Primary
Concomitant
Insomnia Hospitalization 10/21/2010 71 Female 104 lb 5/25/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Death 10/18/2010 58 Male 165 lb 5/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 9/10/2010 61 Male 123 lb 5/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dry Skin Life Threatening 7/15/2010 59 Male 181 lb 6/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death 8/5/2010 70 Male 119 lb 6/3/2011 Other Health Professional Japan
Primary
Concomitant
Pain Other Serious 8/18/2010 66 Male 159 lb 6/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 8/30/2010 75 Female 117 lb 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 12/11/2010 59 Male 137 lb 6/15/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/28/2010 72 Male 119 lb 6/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/28/2010 72 Male 119 lb 6/16/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 9/1/2010 66 Female 110 lb 6/20/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dry Skin Life Threatening 11/4/2010 41 Female 99 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 12/7/2010 55 Female 104 lb 6/29/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 7/15/2010 59 Male 181 lb 6/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/28/2010 72 Male 119 lb 7/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 8/18/2010 66 Male 159 lb 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Death 10/28/2010 72 Male 119 lb 7/4/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Death 11/2/2010 56 Male 240 lb 7/9/2011 Physician Japan
Primary
Concomitant
Dry Skin Hospitalization 11/4/2010 41 Female 99 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 10/28/2010 72 Male 119 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 10/24/2010 75 Female 121 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Death 10/10/2010 61 Female 121 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 9/7/2010 62 Male 95 lb 7/25/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Hospitalization 10/11/2010 78 Male 130 lb 7/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Malaise Other Serious 7/15/2010 68 Male 141 lb 7/27/2011 Other Health Professional Japan
Primary
Concomitant
Dermatitis Death 9/27/2010 80 Male 139 lb 8/2/2011 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 10/27/2010 77 Male 150 lb 8/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Hospitalization 9/14/2010 78 Male 137 lb 8/8/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Glossitis Other Serious 7/30/2010 76 Female 77 lb 8/8/2011 Other Health Professional Japan
Primary
Concomitant
Decreased Appetite Other Serious 10/1/2010 51 Male 163 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 11/11/2010 51 Female 86 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 10/28/2010 72 Male 119 lb 8/12/2011 Physician Japan
Primary
Secondary
Concomitant
Nausea Death 10/10/2010 61 Female 121 lb 8/22/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Colorectal Cancer Other Serious 7/15/2010 68 Male 141 lb 8/22/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 9/27/2010 61 Male 99 lb 8/22/2011 Physician Japan
Primary
Secondary
Concomitant
Colorectal Cancer Death 12/7/2010 55 Female 104 lb 8/30/2011 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data