Amphotericin B combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 4/15/2005 45 Male 2/10/2006 Physician Germany
Primary
Concomitant
Tracheostomy Other Serious 65 Male 2/15/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Administration Error Death 1/1/2004 2 Male 3/16/2006 Physician Poland
Primary
Concomitant
Therapy Non-responder Hospitalization 66 Female 4/7/2006 Physician Denmark
Primary
Concomitant
Therapy Non-responder Hospitalization 66 Female 4/11/2006 Physician Denmark
Primary
Concomitant
Septic Shock Other Serious 66 Male 4/10/2006 Netherlands
Primary
Concomitant
Respiratory Failure Life Threatening 16 Female 4/25/2006 Physician Czech Republic
Primary
Concomitant
Septic Shock Life Threatening 66 Male 4/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 47 Female 6/6/2006 Physician Malaysia
Primary
Concomitant
Pulmonary Haemorrhage Death 5/1/2006 47 Female 110 lb 7/13/2006 Physician Malaysia
Primary
Concomitant
Therapy Non-responder Hospitalization 66 Female 7/19/2006 Physician Denmark
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 6/2/2006 48 Male 7/12/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 6/2/2006 48 Male 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 66 Female 8/4/2006 Physician Denmark
Primary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/8/2006 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/12/2006 Other Health Professional Belgium
Primary
Concomitant
Myocardial Infarction Death 7/20/2006 21 Female 132 lb 9/15/2006 Other Health Professional Belgium
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/12/2006 France
Primary
Concomitant
Systemic Candida Hospitalization 8/2/2006 67 Male 9/13/2006 Physician France
Primary
Concomitant
Syncope Other Serious 6/2/2006 48 Male 9/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 8/1/2004 10 Female 10/19/2006 Germany
Primary
Concomitant
Renal Failure Other Serious 11/4/2002 40 Female 10/20/2006 Physician France
Primary
Concomitant
Pulmonary Mycosis Life Threatening 1/1/2005 Male 12/29/2006 Japan
Primary
Concomitant
Drug Ineffective Death 46 Female 1/22/2007 Physician Iceland
Primary
Concomitant
Staphylococcal Infection Other Serious 19 Male 2/23/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Disability 62 Female 3/9/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 41 Male 3/15/2007 Physician United States
Primary
Concomitant
Pulmonary Mycosis Life Threatening 10/5/2005 Male 3/23/2007 Japan
Primary
Concomitant
Renal Tubular Disorder Death 7 Female 5/24/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/4/2005 69 Male 5/18/2007 Switzerland
Primary
Secondary
Concomitant
Sepsis Life Threatening 5/8/2007 57 Male 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 30 Female 5/25/2007 Physician Australia
Primary
Secondary
Renal Tubular Disorder Other Serious 7 Female 5/30/2007 Physician Italy
Primary
Secondary
Concomitant
Death Death 30 Female 6/4/2007 Physician Australia
Primary
Secondary
Hypotension Other Serious 1/6/2007 Male 49 lb 6/14/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/7/2006 30 Male 6/19/2007 Korea, Republic Of
Primary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/23/2007 61 Male 148 lb 7/6/2007 Physician Korea, Republic Of
Primary
Concomitant
Cerebellar Syndrome Death 5/21/2007 17 Male 7/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Mucormycosis Death 59 Male 7/23/2007 Japan
Primary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Cerebellar Syndrome Death 5/21/2007 16 Male 8/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Mucormycosis Death 59 Male 126 lb 9/4/2007 Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2007 Female 9/6/2007 Physician
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Venous Occlusion Hospitalization 52 Female 9/28/2007 United States
Primary
Concomitant
Multi-organ Failure Hospitalization 63 Female 9/28/2007 United States
Primary
Concomitant
Multi-organ Failure Hospitalization 30 Male 9/28/2007 United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 15 Female 115 lb 10/19/2007 Physician France
Primary
Concomitant
Drug Resistance Other Serious 51 Male 107 lb 11/6/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 15 Female 11/30/2007 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Lymphoproliferative Disorder Hospitalization 15 Female 12/7/2007
Primary
Secondary
Concomitant
Stomatitis Other Serious 6 Male 12/23/2007 Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 22 Male 1/3/2008 Physician United States
Primary
Concomitant
Stomatitis Other Serious 5/1/2007 6 Male 1/3/2008 Japan
Primary
Concomitant
Subcutaneous Abscess Other Serious 52 Male 1/16/2008
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/26/2006 51 Male 172 lb 2/9/2008 Physician France
Primary
Secondary
Concomitant
Liver Disorder Other Serious 3/1/2008 50 Male 3/28/2008 Pharmacist Japan
Primary
Secondary
Liver Disorder Other Serious 3/1/2008 50 Male 4/11/2008 Pharmacist Japan
Primary
Secondary
Weight Increased Other Serious 9/26/2006 Male 172 lb 5/29/2008 Physician France
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/28/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 7/30/2008 Poland
Primary
Concomitant
Tuberculosis Other Serious 63 Female 7/31/2008
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/1/2008 Poland
Primary
Concomitant
Withdrawal Syndrome Hospitalization 16 Female 106 lb 8/22/2008 Poland
Primary
Concomitant
Pancytopenia Death 9/7/2008 55 Female 9/10/2008 Pharmacist Israel
Primary
Concomitant
Neutropenia Other Serious 7 Female 10/6/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 10/14/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Supraventricular Tachycardia Hospitalization 1/1/2003 41 Male 121 lb 10/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Drug Resistance Other Serious 55 Male 10/21/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 10/22/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 41 Male 10/24/2008 United Kingdom
Primary
Concomitant
Interacting
Squamous Cell Carcinoma Of Skin Death 1/1/2006 50 Male 11/5/2008 Consumer United Kingdom
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 41 Male 11/28/2008 United Kingdom
Primary
Concomitant
Interacting
Endocarditis Death 53 Male 12/8/2008
Primary
Concomitant
Pericardial Effusion Death 53 Male 12/17/2008 France
Primary
Concomitant
Septic Shock Hospitalization 11/18/2008 53 Male 12/17/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 24 Male 12/18/2008
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2003 1/12/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Sinusitis Death 78 Male 1/26/2009 Physician Greece
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 36 Male 2/2/2009 Other Health Professional Netherlands
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 3/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Cerebral Aspergillosis Other Serious 42 Male 3/4/2009
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 5 Female 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Unknown 3/3/2009 Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 64 Male 3/13/2009 Other Health Professional Austria
Primary
Concomitant
Ventricular Failure Hospitalization 1/1/2003 3/13/2009 United Kingdom
Primary
Concomitant
Interacting
Splenomegaly Other Serious 24 163 lb 3/17/2009 Consumer Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/1/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/22/2007 58 Male 130 lb 4/6/2009 Physician Belgium
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/26/2007 58 Male 130 lb 4/7/2009 Physician Belgium
Primary
Secondary
Concomitant
Surgery Other Serious 74 Male 4/8/2009 Other Health Professional United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/15/2009
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Sepsis Other Serious 1/1/2007 41 Female 4/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 1/1/2003 41 Male 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Visual Impairment Hospitalization 38 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Viral Infection Death 1/1/2008 67 Male 143 lb 5/29/2009 Physician Belgium
Primary
Concomitant
Systemic Mycosis Hospitalization 7/1/2006 50 Female 5/29/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Toxoplasmosis Hospitalization 18 Female 6/24/2009 Pharmacist United States
Primary
Secondary
Brain Abscess Other Serious 0 Female 7/1/2009
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/14/2004 Male 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 54 Male 7/7/2009 Other Health Professional France
Primary
Concomitant
Interacting
Platelet Count Decreased Hospitalization 18 Female 7/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 6/7/2006 70 7/8/2009 Physician Korea, Republic Of
Primary
Concomitant
Wrong Drug Administered Hospitalization 16 Male 8/7/2009 Physician Netherlands
Primary
Secondary
Concomitant
Sepsis Other Serious 3/6/2009 60 Male 128 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Other Serious 8/1/2006 31 Male 8/21/2009 Physician China
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 48 Male 8/27/2009
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 48 Male 8/24/2009 Physician Australia
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/26/2009 66 9/4/2009 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/26/2009 66 9/11/2009 Physician Germany
Primary
Secondary
Concomitant
Fungal Infection Death 9/28/2009 Physician Canada
Primary
Concomitant
Venoocclusive Disease Hospitalization 8/11/2009 Male 39 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/29/2009 Female 115 lb 10/1/2009 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Death 1/1/2006 50 Male 10/1/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 8/26/2009 66 10/8/2009 Physician Germany
Primary
Secondary
Concomitant
Abscess Hospitalization 10/22/2008 76 10/15/2009 Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 22 Male 10/29/2009
Primary
Secondary
Zygomycosis Other Serious 58 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Transplant Failure Other Serious 14 Female 11/16/2009 Consumer United Kingdom
Primary
Secondary
Visual Impairment Hospitalization 3/20/2009 57 Female 11/20/2009 Consumer France
Primary
Secondary
Concomitant
Systemic Mycosis Hospitalization 7/1/2006 50 Female 11/24/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/26/2009 66 Female 115 lb 12/11/2009 Physician Germany
Primary
Secondary
Concomitant
Stenotrophomonas Infection Other Serious 10/5/2006 35 Female 1/25/2010
Primary
Secondary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 8/26/2009 66 Female 115 lb 2/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Death 46 Male 3/17/2010 Physician United States
Primary
Secondary
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Drug Resistance Death 9 Female 4/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Drug Resistance Death Female 5/6/2010 Other Health Professional France
Primary
Secondary
Concomitant
Multiple-drug Resistance Death 9 Female 5/6/2010 France
Primary
Secondary
Concomitant
Drug Resistance Death 9 Female 5/14/2010 Other Health Professional France
Primary
Secondary
Concomitant
Hypopyon Hospitalization 48 Female 5/17/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Infection Death 4/21/2010 64 Male 6/21/2010 Other Health Professional United States
Primary
Concomitant
Infection Death 4/21/2010 64 Male 6/28/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 43 Male 104 lb 7/20/2010 Taiwan, Province Of China
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 12/26/2009 66 Male 90 lb 7/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/27/2007 56 Male 172 lb 8/6/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Drug Ineffective 15 Female 8/6/2010 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2008 58 Male 8/11/2010 Physician Greece
Primary
Secondary
Concomitant

Drug Data