Amphotericin B combined with Vancomycin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 1/19/2006 Physician United States
Primary
Secondary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2005 72 Male 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Drug Administration Error Death 1/1/2004 2 Male 3/16/2006 Physician Poland
Primary
Concomitant
Tracheal Injury Disability 15 Male 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 7/7/2003 51 Male 216 lb 3/17/2006 United States
Primary
Concomitant
Respiratory Distress Life Threatening 2/18/2006 1 Male 17 lb 3/24/2006 France
Primary
Secondary
Concomitant
Renal Failure Disability 15 Male 3/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 66 Male 4/10/2006 Netherlands
Primary
Concomitant
Respiratory Distress Life Threatening 2/18/2006 1 Male 17 lb 4/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/23/2005 50 Male 126 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Life Threatening 66 Male 4/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Septic Shock Life Threatening 66 Male 5/2/2006 Physician Netherlands
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 9 Male 41 lb 5/8/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Graft Versus Host Disease Hospitalization 8/3/2003 28 Male 4/27/2006 Japan
Primary
Concomitant
Graft Versus Host Disease Hospitalization 3/14/2003 32 Male 4/27/2006 Japan
Primary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/7/2006 Portugal
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/13/2006 United States
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/20/2006 Portugal
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/2/2006 Female 32 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/27/2006 Other Health Professional Portugal
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheal Haemorrhage Hospitalization 5/31/2006 69 Male 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 6/9/2006 48 Female 227 lb 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 1/1/2005 23 Male 7/19/2006 Physician United States
Primary
Concomitant
Febrile Neutropenia Other Serious 7/11/2006 71 Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/8/2006 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/12/2006 Other Health Professional Belgium
Primary
Concomitant
Myocardial Infarction Death 7/20/2006 21 Female 132 lb 9/15/2006 Other Health Professional Belgium
Primary
Concomitant
Pneumonia Life Threatening 5/10/2006 80 Female 9/29/2006 Physician Malaysia
Primary
Concomitant
Prescribed Overdose Hospitalization 27 Male 10/2/2006 Physician Germany
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 7/1/2005 56 Male 8/8/2006 Pharmacist United States
Primary
Concomitant
Pneumatosis Intestinalis Other Serious 10 Male 11/21/2006 United States
Primary
Secondary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 12/26/2006 Physician Belgium
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Life Threatening 1/1/2005 Male 110 lb 12/28/2006 Japan
Primary
Concomitant
Serratia Infection Other Serious 56 Female 12/29/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Mycosis Life Threatening 1/1/2005 Male 12/29/2006 Japan
Primary
Concomitant
Osteopenia Hospitalization 8/4/2005 61 Male 3/1/2007 Physician Belgium
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/10/2005 Male 110 lb 3/16/2007 Japan
Primary
Concomitant
Neurotoxicity Other Serious 56 Female 3/22/2007 United States
Primary
Concomitant
Interacting
Pulmonary Mycosis Life Threatening 10/5/2005 Male 3/23/2007 Japan
Primary
Concomitant
Septic Shock Other Serious 5/23/2007 61 Male 148 lb 7/6/2007 Physician Korea, Republic Of
Primary
Concomitant
Cerebellar Syndrome Death 5/21/2007 17 Male 7/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Overdose Death 7/8/2007 24 Male 207 lb 7/19/2007 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 8/3/2007 Other Health Professional United States
Primary
Secondary
Septic Shock Other Serious 21 Male 8/8/2007 Other Health Professional Korea, Republic Of
Primary
Secondary
Cerebellar Syndrome Death 5/21/2007 16 Male 8/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2007 Female 9/6/2007 Physician
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 0 Male 9 lb 9/11/2007 Poland
Primary
Concomitant
Vomiting Other Serious 8 Male 10/2/2007
Primary
Secondary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Serotonin Syndrome Hospitalization 23 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Transaminases Increased Death 1/1/2007 Male 176 lb 10/26/2007 Physician Germany
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/1/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Pathogen Resistance Death 45 Male 11/2/2007 Other Health Professional Austria
Primary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Restlessness 10/29/2007 64 Male 220 lb 11/13/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/29/2007 64 Male 220 lb 11/19/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Cardiopulmonary Failure Death 7/8/2007 69 Female 12/6/2007 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 10/29/2007 64 Male 220 lb 12/7/2007 United States
Primary
Concomitant
Fungal Sepsis Hospitalization 8/12/2007 Male 208 lb 12/21/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 17 Male 1/18/2008 France
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 3 Male 2/14/2008 Consumer United Kingdom
Primary
Concomitant
Thermal Burn Other Serious 10/31/2003 Male 2/22/2008 Physician Germany
Primary
Secondary
Fungal Skin Infection Hospitalization 62 Male 2/28/2008
Primary
Secondary
Concomitant
Thermal Burn Other Serious 10/31/2003 Male 3/12/2008 Physician Germany
Primary
Secondary
Visual Disturbance Other Serious 1/24/2008 Male 121 lb 3/31/2008 Physician Australia
Primary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Fungal Sepsis Hospitalization 8/12/2007 Male 208 lb 4/18/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 Male 165 lb 4/24/2008 Pharmacist United States
Primary
Secondary
Concomitant
Necrotising Colitis Other Serious 2/13/2008 0 Male 3 lb 5/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Streptococcal Infection Life Threatening 44 Male 5/23/2008 Other Health Professional France
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 5/22/2008 Consumer United States
Primary
Secondary
Concomitant
Necrotising Colitis Other Serious 2/13/2008 0 Male 3 lb 6/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 9 Female 7/3/2008
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/3/2007 33 Female 11/6/2008 United Kingdom
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 9/3/2007 33 Female 11/10/2008 Japan
Primary
Secondary
Concomitant
Vertical Infection Transmission Other Serious 8/5/2008 Male 11/24/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 41 Male 11/17/2008 Taiwan, Province Of China
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 11/5/2008 63 Male 11/20/2008 Other Health Professional Spain
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 0 Male 11/25/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 11/5/2008 63 Male 12/4/2008 Other Health Professional Spain
Primary
Concomitant
Liver Disorder Death 9/3/2007 33 Female 12/26/2008 Japan
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 9/3/2007 33 Female 12/31/2008 Japan
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Abscess Hospitalization 10/22/2008 2/2/2009 Germany
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Hospitalization 1/1/2009 Male 157 lb 2/4/2009 Other Health Professional Germany
Primary
Concomitant
Pneumonia Cryptococcal Hospitalization 11/22/2008 Male 220 lb 2/9/2009 United States
Primary
Secondary
Concomitant
Hypotension Other Serious 21 Male 2/20/2009 Other Health Professional Canada
Primary
Concomitant
Drug Interaction Other Serious 2/10/2009 58 Female 282 lb 3/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 7/27/2002 Male 185 lb 2/10/2009 Physician United States
Primary
Concomitant
Sepsis Other Serious 64 Male 3/13/2009 Other Health Professional Austria
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 2/3/2009 44 Female 110 lb 3/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/11/2007 7 Female 67 lb 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 12/12/2008 68 Male 101 lb 5/29/2009 Other Health Professional Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 9/20/2003 Female 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11 Male 6/19/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 5/2/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/2/2005 Male 7/1/2009 Physician United States
Primary
Concomitant
Death Death 6/7/2006 70 7/8/2009 Physician Korea, Republic Of
Primary
Concomitant
Encephalopathy Hospitalization 1/30/2001 49 Female 8/6/2009 Physician New Zealand
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/20/2003 50 Female 8/5/2009 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Function Test Abnormal Other Serious 47 Male 9/3/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/31/2008 Male 9/10/2009 Japan
Primary
Concomitant
Renal Failure Acute Death 12/1/2008 68 Male 101 lb 9/21/2009 Other Health Professional Japan
Primary
Concomitant
Drug Ineffective Hospitalization 53 Female 9/22/2009 Physician Turkey
Primary
Concomitant
Respiratory Disorder Other Serious 6/14/2007 47 Male 9/17/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 8/11/2009 Male 39 lb 9/16/2009 United States
Primary
Secondary
Concomitant
Abscess Hospitalization 10/22/2008 76 10/15/2009 Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 22 Male 10/29/2009
Primary
Secondary
Fungaemia Death 70 Female 12/15/2009 Physician Korea, Republic Of
Primary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2 Male 2/2/2010
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Life Threatening 11/5/2007 Male 150 lb 3/2/2010 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Other Serious 58 Female 3/9/2010 Physician United States
Primary
Concomitant
Ventricular Septal Defect Other Serious 8/5/2008 Male 3/15/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 1/31/2008 Male 3/19/2010 Japan
Primary
Concomitant
Interacting
Ventricular Septal Defect Other Serious 8/5/2008 Male 5/3/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 2/8/2010 67 Male 179 lb 5/5/2010 Germany
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2010 47 Female 130 lb 5/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypopyon Hospitalization 48 Female 5/17/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 0 Female 7 lb 6/2/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 2/8/2010 67 Male 179 lb 6/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/7/2010 47 Female 130 lb 6/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Infection Death 4/21/2010 64 Male 6/21/2010 Other Health Professional United States
Primary
Concomitant
Vaginal Lesion Hospitalization 4/14/2010 3 Female 43 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/4/2010 3 Female 43 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 39 Male 165 lb 6/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Death 4/21/2010 64 Male 6/28/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant

Drug Data