Amphotericin B combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 4/25/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 7/8/2005 61 Female 5/23/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Acute Febrile Neutrophilic Dermatosis Hospitalization 24 Female 10/11/2006 Physician Turkey
Primary
Concomitant
Sepsis Hospitalization 8/4/2005 61 Male 11/24/2006 Physician Belgium
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 5/1/2006 41 Male 11/29/2006 Physician France
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 5/1/2006 41 Male 12/12/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/1/2005 49 Female 6/6/2007 Belgium
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 5/1/2006 41 Male 7/10/2007 Physician France
Primary
Secondary
Concomitant
Vasculitis Death 6/22/2007 50 Female 7/5/2007 Physician Belgium
Primary
Secondary
Concomitant
Overdose Death 7/8/2007 24 Male 207 lb 7/19/2007 Pharmacist United States
Primary
Concomitant
Neurological Symptom Hospitalization 58 Male 9/27/2007 Other Health Professional France
Primary
Secondary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/8/2007 Other Health Professional Malaysia
Primary
Concomitant
Sepsis Death 5/1/2004 42 Female 10/12/2007 Other Health Professional Malaysia
Primary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 34 Male 161 lb 11/9/2007 Physician Germany
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Creatinine Renal Clearance Decreased Other Serious 53 Female 1/16/2008 Physician Japan
Primary
Concomitant
Troponin I Increased Death 11/1/2007 52 Female 143 lb 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 12 Female 3/1/2008 Physician United States
Primary
Concomitant
Lung Infection Other Serious 12/7/2007 67 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/7/2007 67 Male 4/1/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/7/2007 67 Male 4/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin I Increased Death 11/1/2007 52 Female 143 lb 5/17/2008 Physician Germany
Primary
Secondary
Concomitant
Varices Oesophageal Other Serious 5/1/2006 41 Male 5/23/2008 France
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/6/2008
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 45 Male 6/18/2008
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/24/2008 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/25/2008 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/28/2008 Physician China
Primary
Concomitant
Respiratory Failure Life Threatening 6/24/2008 66 Male 7/30/2008 Physician China
Primary
Secondary
Concomitant
Zygomycosis Other Serious 43 Male 9/19/2008 Other Health Professional Canada
Primary
Secondary
Subcutaneous Nodule Other Serious 49 Female 1/26/2009
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/18/2009 12 Female 110 lb 3/3/2009 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 2/18/2009 12 Female 110 lb 3/11/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 2/11/2009 35 Male 174 lb 3/18/2009 Physician Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 2/11/2009 35 Male 174 lb 3/20/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 2/11/2009 35 Male 174 lb 3/30/2009 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 11/12/1999 15 Male 4/3/2009 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 3/7/2009 60 Male 128 lb 5/11/2009 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 38 Female 5/21/2009 Physician United States
Primary
Secondary
Concomitant
Renal Artery Stenosis Hospitalization 10/24/2003 Male 161 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 5/20/2003 Male 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2003 Male 132 lb 6/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 Male 198 lb 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/16/2006 Female 6/23/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 11 Male 6/19/2009 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 9/16/2004 49 Male 6/30/2009 Physician Czech Republic
Primary
Secondary
Concomitant
Hepatic Failure Death 2/23/2009 52 Male 117 lb 6/29/2009 Physician Japan
Primary
Concomitant
Suture Rupture Life Threatening 8/26/2004 33 Male 7/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 2/1/2009 50 Female 117 lb 7/30/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/1/1997 31 Male 8/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 3/6/2009 60 Male 128 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Other Serious 8/1/2006 31 Male 8/21/2009 Physician China
Primary
Secondary
Concomitant
Wound Dehiscence Death 57 Male 10/15/2009 Physician Italy
Primary
Secondary
Concomitant
Transmission Of An Infectious Agent Via A Medicinal Product Death 57 Female 10/15/2009 Physician Italy
Primary
Secondary
Concomitant
Hemiplegia Other Serious 8/11/2009 16 Male 11/6/2009 Other Health Professional France
Primary
Secondary
Concomitant
Septic Embolus Other Serious 24 Female 1/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 2 Female 2/5/2010
Primary
Secondary
Concomitant
Sepsis Death 24 Female 2/8/2010 United Kingdom
Primary
Secondary
Hepatic Failure Life Threatening 2/23/2009 52 Male 126 lb 2/16/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization Female 125 lb 4/28/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Cytomegaloviral Life Threatening 2/14/2009 52 Male 126 lb 4/20/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 43 Male 104 lb 7/20/2010 Taiwan, Province Of China
Primary
Secondary
Concomitant
Zygomycosis Life Threatening 2/2/2009 60 Male 130 lb 7/22/2010 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 8/30/2010 Physician Italy
Primary
Concomitant
Unevaluable Event Other Serious Male 8/30/2010 Physician Italy
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/22/2009 22 Female 77 lb 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 9 Female 9/30/2010 Physician Italy
Primary
Concomitant
Toxoplasmosis Death 42 Female 10/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 5/11/2009 70 Female 86 lb 10/15/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 2/8/2010 38 Male 146 lb 11/8/2010 Physician Japan
Primary
Concomitant
Haemorrhagic Stroke Death 46 Male 12/3/2010 Other Health Professional Greece
Primary
Concomitant
Enterococcal Sepsis Death 11 Female 12/17/2010 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Death 11 Female 12/21/2010 United States
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 16 1/28/2011 Physician Israel
Primary
Secondary
Concomitant
Anaphylactic Shock Hospitalization 2/11/2009 35 Male 174 lb 1/17/2011 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 16 2/7/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Failure Death 2/11/2011 57 Female 4/20/2011 Physician Germany
Primary
Concomitant
Dyspnoea Other Serious 6/22/2009 22 Female 77 lb 4/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Aspergillosis Other Serious 49 Male 5/23/2011 Physician Japan
Primary
Concomitant
Subcutaneous Nodule Other Serious 63 Male 6/15/2011 Other Health Professional United States
Primary
Secondary
Renal Haemorrhage Other Serious 1/1/2007 63 Female 6/30/2011 Other Health Professional Japan
Primary
Concomitant
Acute Respiratory Failure Death 58 Male 7/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enterobacter Pneumonia Death Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death Female 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Artery Embolism Death 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death Female 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Other Serious Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Death Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Death Female 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death Female 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious Female 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious Male 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Death Female 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Death Female 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Sinusitis Other Serious Female 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Diarrhoea Other Serious Male 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious Male 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Death Male 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death Male 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Graft Versus Host Disease Death Female 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Enterobacter Pneumonia Death Male 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death Female 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Haematuria Other Serious 1/1/2011 21 Female 119 lb 9/23/2011 Pharmacist Brazil
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Life Threatening 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 10/21/2009 22 Female 104 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 10/21/2009 22 Female 104 lb 10/11/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 7/4/2011 41 Male 117 lb 10/14/2011 Physician Japan
Primary
Concomitant
Nephropathy Toxic Life Threatening 34 Male 10/31/2011 Other Health Professional Korea, Republic Of
Primary
Secondary
Viral Haemorrhagic Cystitis Death 6/24/2010 29 Female 99 lb 12/8/2011 Other Health Professional Japan
Primary
Concomitant
Pseudomonal Sepsis Death 10/21/2009 22 Female 104 lb 2/21/2012 Physician Japan
Primary
Secondary
Concomitant
Arthropathy Hospitalization 1/1/2011 65 Female 141 lb 2/24/2012 Physician Germany
Primary
Concomitant
Myocarditis Death 76 Male 2/28/2012 Physician Japan
Primary
Concomitant
Leukopenia Hospitalization 1/1/2011 65 Female 141 lb 3/1/2012 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Death 6/24/2010 29 Female 99 lb 3/2/2012 Other Health Professional Japan
Primary
Concomitant
Condition Aggravated Other Serious 76 Male 3/9/2012 Other Health Professional China
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 5/13/2010 Male 20 lb 3/13/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 2/17/2011 65 Female 141 lb 3/20/2012 Other Health Professional Germany
Primary
Concomitant
Zygomycosis Other Serious 76 Male 4/3/2012 Other Health Professional China
Primary
Secondary
Concomitant
Renal Impairment Other Serious 4/6/2011 12 Male 97 lb 5/15/2012 Physician Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 9/18/2011 1 Male 24 lb 5/15/2012 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 11/1/2010 6 Female 42 lb 5/17/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 8/19/2010 13 Male 97 lb 5/18/2012 Physician Japan
Primary
Concomitant
Serum Ferritin Increased Death 11/1/2010 6 Female 42 lb 5/22/2012 Physician Japan
Primary
Concomitant
Arthropathy Hospitalization 2/17/2011 65 Female 141 lb 6/26/2012 Physician Germany
Primary
Concomitant
Sepsis Life Threatening 6/24/2010 29 Female 99 lb 6/29/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Candidiasis Hospitalization 5/1/2012 63 Female 7/13/2012 Other Health Professional France
Primary
Secondary
Concomitant
Engraftment Syndrome Hospitalization 11/1/2010 6 Female 42 lb 7/19/2012 Physician Japan
Primary
Concomitant
Aplasia Other Serious 6/4/2012 64 Female 7/27/2012 Other Health Professional France
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2012 Male 13 lb 7/27/2012 Physician Guatemala
Primary
Concomitant
Encephalopathy Hospitalization 6/4/2012 63 Female 7/17/2012 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/10/2011 20 Male 157 lb 8/8/2012 Greece
Primary
Concomitant
Interacting
Cytomegalovirus Test Positive Other Serious 6/24/2010 29 Female 99 lb 8/13/2012 Physician Japan
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 6/4/2012 63 Female 7/27/2012 Physician France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 10/1/2010 8/20/2012 Physician Austria
Primary
Concomitant
Suture Rupture Hospitalization 8/26/2004 33 Male 201 lb 12/18/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Pseudomonal Sepsis Other Serious 10/21/2009 23 Female 104 lb 4/15/2013 Physician Jp
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 4/6/2011 13 Male 97 lb 12/27/2012 Physician Jp
Primary
Secondary
Concomitant
Urticaria Hospitalization 9/18/2011 1 Male 24 lb 11/21/2012 Physician Jp
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 11/1/2010 6 Female 42 lb 5/13/2013 Physician Jp
Primary
Concomitant
Venoocclusive Disease Hospitalization 8/19/2010 13 Male 97 lb 11/22/2012 Physician Jp
Primary
Concomitant
Pruritus Hospitalization 11/2009 65 Female 10/27/2012 Other Health Professional De
Primary
Secondary
Interacting
Urinary Tract Infection Hospitalization 1/16/2006 66 Female 12/13/2012 Physician Cz
Primary
Secondary
Concomitant
Refractory Cytopenia With Unilineage Dysplasia Death 5/1/2011 74 Male 12/28/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Nocardiosis Hospitalization 6/2008 67 Male 3/22/2013 Other Health Professional Jp
Primary
Secondary
Concomitant
Visual Impairment Death 8/24/2013 32 Female 112 lb 9/27/2013 Other Health Professional Cn
Primary
Concomitant

Drug Data