Amphotericin B combined with Etoposide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Liver Disease Other Serious 3/28/2006 49 Female 127 lb 4/11/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Pneumonia Respiratory Syncytial Viral Death 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Cardiomyopathy Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Herpes Oesophagitis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Pericarditis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Pericarditis Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Facial Palsy Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 1/1/1999 4/11/2006 Physician United States
Primary
Concomitant
Drug Toxicity Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 1/1/1999 4/11/2006 Physician United States
Primary
Concomitant
Drug Toxicity Required Intervention 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/28/2006 49 Female 127 lb 4/21/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Death 5/7/2006 71 Male 5/31/2006 Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 10 Male 6/9/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Fungal Infection Death 5/7/2006 71 Male 6/6/2006 Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/7/2006 Portugal
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 55 Female 6/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 10 Male 6/15/2006 Germany
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/20/2006 Portugal
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/2/2006 Female 32 lb 6/14/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 55 Female 7/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Trichosporon Infection Hospitalization 4/24/2006 57 Male 245 lb 8/1/2006 United States
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Other Serious 10 Male 11/21/2006 United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 11/10/2005 5 Female 2/8/2007 Spain
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6 Female 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 3/28/2006 Female 127 lb 4/13/2007 Australia
Primary
Secondary
Concomitant
Stridor Death 6 Female 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Death 7 Female 5/24/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 5/30/2007 Physician Italy
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 8/3/2007 Other Health Professional United States
Primary
Secondary
Renal Tubular Disorder Other Serious 7 Female 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Septic Shock Death 6/30/2007 69 Male 8/15/2007 Italy
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/13/2007 53 Male 8/21/2007 Other Health Professional United States
Primary
Secondary
Renal Failure Other Serious 7/13/2007 53 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 7/13/2007 53 Male 8/24/2007 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Life Threatening 7/1/2007 53 Male 8/27/2007 Physician United States
Primary
Secondary
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6 Female 9/24/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 9/27/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2007 59 Male 260 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Protein Total Decreased Other Serious 9/1/2007 Male 194 lb 10/29/2007 Physician Serbia And Montenegro
Primary
Concomitant
Pneumonitis Hospitalization 6 Female 11/28/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiopulmonary Failure Death 7/8/2007 69 Female 12/6/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 17 Male 1/18/2008 France
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 6 Female 4/24/2008 Consumer United States
Primary
Secondary
Concomitant
Sputum Culture Positive Hospitalization 6 Female 4/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Pyrexia Other Serious 5/19/2008 Physician Germany
Primary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 5/22/2008 Consumer United States
Primary
Secondary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
Zygomycosis Hospitalization 1 Male 6/17/2008
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 7/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/31/2008 Male 8/6/2008 Physician Japan
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious Male 8/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenia Other Serious 7 Female 10/6/2008 Other Health Professional Austria
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 4 Female 11/21/2008
Primary
Secondary
Concomitant
Stomatitis Necrotising Other Serious 8/19/1993 Male 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/22/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/23/2008
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/23/2008
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/1/1997 31 Male 8/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Death 53 Female 108 lb 8/31/2009 Other Health Professional Belgium
Primary
Concomitant
Pulmonary Function Test Abnormal Other Serious 47 Male 9/3/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 1/31/2008 Male 9/10/2009 Japan
Primary
Concomitant
Respiratory Disorder Other Serious 6/14/2007 47 Male 9/17/2009 Pharmacist Australia
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 6/12/2009 64 Male 10/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Stenotrophomonas Infection Other Serious 10/5/2006 35 Female 1/25/2010
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/21/2009 65 Female 2/18/2010 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 4/21/2009 65 Female 2/22/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 3/12/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 1/31/2008 Male 3/19/2010 Japan
Primary
Concomitant
Interacting
Fusarium Infection Other Serious 8 Male 5/17/2010 Physician Italy
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2009 61 Female 6/15/2010 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 5/4/2010 26 Male 187 lb 7/2/2010 Physician South Africa
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 8/6/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Life Threatening 11/8/2007 20 Male 118 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 59 Female 132 lb 9/1/2010 Physician Germany
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 33 Male 9/20/2010 Physician Argentina
Primary
Secondary
Sepsis Other Serious 5/4/2010 26 Male 187 lb 9/21/2010 Physician South Africa
Primary
Secondary
Concomitant
Hepatitis B Surface Antigen Positive Required Intervention 57 Female 9/17/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 15 Male 9/23/2010 Consumer Germany
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 11/3/2010 Physician Japan
Primary
Concomitant
Vaginal Haemorrhage Required Intervention 9/13/2010 18 Female 121 lb 11/29/2010 Pharmacist Canada
Primary
Concomitant
Pneumonia Fungal Other Serious 5/18/2010 5 Female 57 lb 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Required Intervention 9/13/2010 18 Female 121 lb 12/17/2010 Pharmacist Canada
Primary
Concomitant
Bone Marrow Failure Death 5/18/2010 5 Female 57 lb 1/5/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Rectal Haemorrhage Other Serious 5/10/2007 67 Female 140 lb 1/4/2011 Physician Netherlands
Primary
Secondary
Concomitant
Adult T-cell Lymphoma/leukaemia Death Female 126 lb 1/13/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Death 9/21/2009 62 Female 126 lb 1/26/2011 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 50 Male 2/4/2011 Other Health Professional Netherlands
Primary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Bone Marrow Failure Other Serious 3/10/2010 62 Male 280 lb 2/18/2011 Physician Germany
Primary
Concomitant
Bone Marrow Failure Other Serious 3/10/2010 62 Male 280 lb 4/6/2011 Other Health Professional Germany
Primary
Concomitant
Fungal Skin Infection Hospitalization 5/18/2010 5 Female 57 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/18/2009 15 Female 126 lb 4/20/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 63 Female 4/21/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Ineffective Death 63 Female 4/21/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 8/6/2006 63 Female 4/25/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Death 54 Male 4/29/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Death 54 Male 5/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/18/2009 15 Female 126 lb 6/1/2011 Consumer United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/18/2009 15 Female 126 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Nodule Other Serious 63 Male 6/15/2011 Other Health Professional United States
Primary
Secondary
Bone Marrow Failure Death 3/10/2010 62 Male 280 lb 6/16/2011 Other Health Professional Germany
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 3/25/2011 10 Male 144 lb 7/8/2011 Physician Argentina
Primary
Secondary
Concomitant
Headache Death 2/19/2009 23 Female 7/27/2011 Consumer Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/19/2009 23 Female 8/2/2011 Physician Japan
Primary
Concomitant
Bone Pain Death 7/17/1992 8/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Histiocytosis Haematophagic Other Serious 3/25/2011 10 Male 74 lb 9/8/2011 Physician Argentina
Primary
Secondary
Concomitant
Lung Infection Pseudomonal Death 9/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 9/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 44 Male 9/24/2011 Other Health Professional Australia
Primary
Secondary
Fungal Infection Death 54 Male 10/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 3 Female 10/7/2011 Physician Greece
Primary
Concomitant
Neutropenia Other Serious 1/1/2009 51 Male 11/10/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 10/18/2011 42 Male 163 lb 11/10/2011 Consumer United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2011 Physician Japan
Primary
Concomitant
Blood Bilirubin Increased Death 12/7/1996 74 Female 154 lb 12/23/2011 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 2/19/2009 23 Female 3/5/2012 Physician Japan
Primary
Concomitant
Convulsion Life Threatening 5/22/2011 6 Male 40 lb 3/12/2012 Physician Japan
Primary
Concomitant
Pericardial Effusion Other Serious 2/19/2009 23 Female 3/13/2012 Physician Japan
Primary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/5/2012 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Death 2/18/2009 10 Female 44 lb 4/5/2012 Consumer Japan
Primary
Secondary
Concomitant
Hyperthermia Life Threatening 3/27/2012 65 Female 134 lb 4/13/2012 Physician Spain
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 4/19/2012 Physician Germany
Primary
Secondary
Concomitant
Bronchitis Hospitalization 4/4/2011 55 Male 212 lb 5/30/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data