Amlodipine combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypoaesthesia Oral Other Serious 43 Male 1/6/2006 Canada
Primary
Concomitant
Ventricular Fibrillation Death 5/21/2005 41 Female 2/27/2006
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 1/23/2006 74 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 5/21/2005 40 Female 2/23/2006 Norway
Primary
Secondary
Concomitant
Myopathy Other Serious 43 Male 3/6/2006 Canada
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 6/2/2006 Consumer United Kingdom
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/17/2006 Other Health Professional Japan
Primary
Concomitant
Tardive Dyskinesia Other Serious 2/1/2006 53 Male 154 lb 7/26/2006 Other Health Professional Japan
Primary
Concomitant
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 9/11/2006 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Drug Toxicity Death 43 Female 183 lb 10/4/2006 United Kingdom
Primary
Concomitant
Drug Toxicity Death 43 Female 183 lb 10/9/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/29/2005 72 Male 12/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vaginal Infection Other Serious 3/1/2006 Female 133 lb 1/23/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 3/5/2007 Consumer United Kingdom
Primary
Concomitant
Haematoma Hospitalization 10/1/2006 86 Female 3/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Nightmare Other Serious 10/25/2006 Female 108 lb 3/19/2007 Physician France
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 12/11/2006 Female 243 lb 7/6/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 255 lb 7/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/18/2007 56 Male 8/1/2007 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 8/21/2007 Consumer Germany
Primary
Concomitant
Platelet Count Increased Other Serious 7/9/2007 50 Male 320 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 181 lb 9/7/2007 Physician Germany
Primary
Concomitant
Overdose Life Threatening 52 Male 9/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 Male 181 lb 10/4/2007 Physician Germany
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Steatosis 47 Female 10/9/2007 Physician United Kingdom
Primary
Concomitant
Pain In Extremity Other Serious 5/1/2007 68 Male 198 lb 10/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Parathyroidectomy Hospitalization 11/1/2006 40 Female 121 lb 10/23/2007 Consumer Colombia
Primary
Concomitant
Cerebrovascular Disorder Other Serious 8/29/2007 84 Female 11/12/2007 Physician United Kingdom
Primary
Concomitant
Death Death 8/29/2007 84 Female 11/20/2007 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Hospitalization 52 Male 12/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 52 Male 12/14/2007 United Kingdom
Primary
Secondary
Overdose Life Threatening 52 Male 12/11/2007 Physician United Kingdom
Primary
Secondary
Overdose Hospitalization 52 Male 176 lb 12/26/2007 United Kingdom
Primary
Secondary
Overdose Hospitalization 52 Male 176 lb 1/31/2008 United Kingdom
Primary
Secondary
Cerebrovascular Accident Other Serious 11/21/2006 2/14/2008 Physician Canada
Primary
Concomitant
Overdose Life Threatening 52 Male 176 lb 3/14/2008 United Kingdom
Primary
Secondary
Red Blood Cell Count Decreased Other Serious 11/12/2005 94 Female 5/1/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 11/12/2005 94 Female 5/5/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Septic Shock Hospitalization 5/15/2007 Female 132 lb 5/5/2008 Consumer Netherlands
Primary
Concomitant
Hyponatraemia Hospitalization 6/16/2008 58 Female 7/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 12/12/2007 Female 7/15/2008 Other Health Professional
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 4/1/2008 90 Male 7/29/2008 Consumer France
Primary
Secondary
Concomitant
Death Death 8/29/2007 84 Female 8/4/2008 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Life Threatening 52 Male 176 lb 8/14/2008 United Kingdom
Primary
Secondary
No Adverse Event 52 Male 8/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Pain In Extremity Hospitalization 68 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spider Naevus Hospitalization 7/2/2008 70 Female 9/3/2008 Physician United Kingdom
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 8/8/2008 Male 161 lb 10/15/2008 Other Health Professional France
Primary
Concomitant
Respiratory Failure Life Threatening 8/12/2008 Female 146 lb 11/12/2008 Other Health Professional Germany
Primary
Concomitant
Unresponsive To Stimuli Death 4/26/2008 75 Male 183 lb 2/2/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulse Absent Other Serious 38 Male 3/13/2009
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 69 Male 4/29/2009 Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 69 Male 4/30/2009 Physician Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/1/2009 91 Female 6/11/2009 Pharmacist United Kingdom
Primary
Concomitant
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/1/2009 Pharmacist United Kingdom
Primary
Concomitant
Suicide Attempt Hospitalization 5/1/2009 91 Female 170 lb 7/7/2009 Pharmacist United Kingdom
Primary
Concomitant
Tracheostomy Life Threatening 7/27/2007 Female 258 lb 7/30/2009 Physician United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2007 68 Male 7/28/2009 United Kingdom
Primary
Concomitant
Overdose Other Serious 52 Male 7/31/2009 United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/24/2009 Female 8/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastrointestinal Stoma Complication Hospitalization 6/27/2009 Male 8/19/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/24/2009 Female 8/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 81 Female 8/26/2009 United Kingdom
Primary
Concomitant
Basal Cell Carcinoma Other Serious 6/21/2007 Female 176 lb 9/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 43 Female 9/16/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/11/2009 Female 171 lb 10/1/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 9/14/2009 Female 154 lb 10/5/2009 Physician Ireland
Primary
Secondary
Concomitant
Infection Hospitalization 9/14/2009 Female 154 lb 10/22/2009 Physician Ireland
Primary
Secondary
Concomitant
Sinus Arrhythmia Hospitalization 6/9/2008 Male 11/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/11/2009 Female 171 lb 11/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Death Death 8/29/2007 84 Female 11/30/2009 Physician United Kingdom
Primary
Concomitant
Infection Hospitalization 9/14/2009 Female 154 lb 12/4/2009 Physician Ireland
Primary
Secondary
Concomitant
Thirst Other Serious 3/13/2009 83 Male 205 lb 12/14/2009 Other Health Professional Canada
Primary
Concomitant
Hyponatraemia Disability 11/28/2009 79 Female 12/14/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 11/28/2009 79 Female 12/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious Male 12/24/2009 Pharmacist
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/26/2008 75 Male 183 lb 12/17/2009 Pharmacist Germany
Primary
Concomitant
Volvulus Hospitalization 12/11/2009 Male 159 lb 12/28/2009 Physician United Kingdom
Primary
Concomitant
Volvulus Hospitalization 12/11/2009 Male 159 lb 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Volvulus Hospitalization 12/11/2009 Male 159 lb 1/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 12/12/2007 Female 2/11/2010
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2008 78 Male 196 lb 2/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2009 Female 104 lb 3/4/2010 Physician Japan
Primary
Concomitant
Pain Disability 3/7/2010 69 Female 3/23/2010 Consumer Canada
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 12/15/2008 Male 3/29/2010 Physician Ireland
Primary
Secondary
Concomitant
Tongue Biting Other Serious 2/1/2010 48 Female 4/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Twitching Other Serious 78 Male 5/6/2010 Consumer Sweden
Primary
Concomitant
Pulmonary Embolism Other Serious Male 5/10/2010 Pharmacist
Primary
Concomitant
Muscle Twitching Other Serious 8/14/2009 78 Male 6/18/2010 Physician Sweden
Primary
Concomitant
Myocardial Ischaemia Death 9/27/2009 87 Female 6/23/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Myocardial Ischaemia Death Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Death Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 6/18/2010 87 Female 7/8/2010 Physician Norway
Primary
Concomitant
Interacting
Sedation Other Serious 6/18/2010 87 Female 7/9/2010 Physician Norway
Primary
Concomitant
Interacting
Interstitial Lung Disease Hospitalization 6/18/2010 62 Male 7/15/2010 Physician Canada
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 6/18/2010 62 Male 8/20/2010 Physician Canada
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 8/14/2010 88 Female 9/7/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 8/14/2010 88 Female 9/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Life Threatening 8/14/2010 88 Female 9/8/2010 United Kingdom
Primary
Concomitant
Tachypnoea Life Threatening 8/14/2010 9/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 8/14/2010 88 Female 9/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Biting Other Serious 2/1/2010 48 Female 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Twitching Other Serious 8/14/2009 77 Male 9/16/2010 Physician Sweden
Primary
Concomitant
Sedation Other Serious 6/18/2010 87 Female 9/16/2010 Physician Norway
Primary
Concomitant
Interacting
Rales Other Serious 8/14/2010 88 Female 9/15/2010 Other Health Professional
Primary
Secondary
Concomitant
Tongue Biting Other Serious 2/1/2010 48 Female 4/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Muscle Twitching Other Serious 8/14/2009 78 Male 6/18/2010 Physician Sweden
Primary
Concomitant
Sedation Other Serious 6/18/2010 87 Female 7/9/2010 Physician Norway
Primary
Concomitant
Interacting
Opportunistic Infection Hospitalization 3/14/2010 66 Male 155 lb 2/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Male 4/27/2011 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 44 Male 4/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2010 69 Female 5/5/2011 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/15/2010 69 Female 5/20/2011 Physician United Kingdom
Primary
Concomitant
Vision Blurred Hospitalization 3/17/2011 60 Female 6/2/2011 Physician France
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 1/1/2010 86 Male 106 lb 6/23/2011 Japan
Primary
Concomitant
Leukopenia Hospitalization 5/26/2011 42 Female 7/7/2011 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2010 86 Male 106 lb 7/12/2011 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 7/1/2010 80 Male 123 lb 7/22/2011 Pharmacist Japan
Primary
Concomitant
Death Death 49 7/28/2011 Physician Denmark
Primary
Secondary
Hallucination, Visual Other Serious 8/1/2010 84 Female 8/2/2011 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 7/1/2010 80 Male 123 lb 8/4/2011 Pharmacist Japan
Primary
Concomitant
Fall Hospitalization 6/15/2011 85 Male 8/8/2011 Physician France
Primary
Concomitant
Toxicity To Various Agents Death 49 8/15/2011 Other Health Professional Denmark
Primary
Secondary
Ankle Fracture Hospitalization 3/26/2011 63 Female 187 lb 8/31/2011 Consumer United States
Primary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 137 lb 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/15/2010 69 Female 9/2/2011 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 86 Male 106 lb 9/9/2011 Other Health Professional Japan
Primary
Concomitant
Nausea Disability 11/9/2009 82 Female 137 lb 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 83 Female 10/10/2011 Consumer Sweden
Primary
Concomitant
Renal Failure Death 11/8/2010 99 Female 10/27/2011 Physician United Kingdom
Primary
Concomitant
Rash Erythematous Hospitalization 1/1/2010 86 Male 106 lb 10/25/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 12/13/2010 77 Male 223 lb 11/30/2011 United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 12/27/2010 75 Male 196 lb 11/30/2011 United Kingdom
Primary
Concomitant
Cardiac Arrest Hospitalization 12/27/2010 75 Male 196 lb 12/15/2011 Physician United Kingdom
Primary
Concomitant
Herpes Simplex Hospitalization 12/30/2011 46 Female 126 lb 1/10/2012 Physician Canada
Primary
Concomitant
Pancreatitis Hospitalization 11/19/2011 48 Male 176 lb 1/19/2012 Other Health Professional Canada
Primary
Concomitant
Hypoglycaemia Hospitalization 12/27/2010 75 Male 196 lb 1/20/2012 Physician United Kingdom
Primary
Concomitant
Antipsychotic Drug Level Above Therapeutic Other Serious 1/1/2010 55 Female 1/23/2012 Physician United Kingdom
Primary
Concomitant
Rash Hospitalization 12/30/2011 46 Female 126 lb 1/13/2012 Physician Canada
Primary
Concomitant

Drug Data