Amlodipine combined with Sunitinib Malate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombotic Microangiopathy Other Serious 56 Male 12/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Male 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 56 Male 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 8/30/2008 49 Male 198 lb 10/10/2008 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 10/10/2008 Female 256 lb 12/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 9/13/2008 57 Male 198 lb 12/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 11/3/2008 1/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2008 1/5/2009 Other Health Professional United Kingdom
Primary
Concomitant
Infection Hospitalization 1/15/2007 Female 273 lb 1/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/19/2008 1/26/2009 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 1/28/2009 Physician France
Primary
Concomitant
Gastritis Hospitalization 1/10/2009 2/5/2009 Physician India
Primary
Concomitant
Renal Failure Acute Hospitalization 10/22/2008 2/9/2009 Physician France
Primary
Concomitant
Nausea Hospitalization 8/25/2006 3/11/2009 Other Health Professional Australia
Primary
Concomitant
Platelet Count Increased Other Serious 1/11/2009 3/13/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 3/18/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 3/18/2009 Physician Japan
Primary
Concomitant
Renal Failure Disability 5/21/2008 3/25/2009 Physician Israel
Primary
Concomitant
Interstitial Lung Disease Other Serious 12/11/2008 4/3/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 12/11/2008 4/8/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 12/24/2008 4/9/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 2/11/2009 4/9/2009 Physician United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 5/21/2008 4/9/2009 Physician Israel
Primary
Concomitant
Myocardial Infarction Life Threatening 3/30/2009 Male 180 lb 4/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 3/30/2009 Male 180 lb 4/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 3/31/2009 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious Male 200 lb 4/27/2009 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 3/15/2009 57 5/8/2009 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 3/30/2009 Male 180 lb 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Cholangitis Life Threatening 4/21/2009 68 5/15/2009 Physician Turkey
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious Male 201 lb 5/22/2009 Consumer United States
Primary
Concomitant
Sepsis Other Serious 4/13/2009 79 5/25/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 4/17/2007 79 5/28/2009 Physician Venezuela
Primary
Concomitant
Sepsis Other Serious 4/13/2009 79 6/9/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2008 69 6/10/2009 Physician Japan
Primary
Concomitant
Reflux Oesophagitis Hospitalization 2/12/2008 68 6/12/2009 Physician Taiwan, Province Of China
Primary
Concomitant
Renal Impairment Other Serious 5/21/2008 71 6/15/2009 Physician Israel
Primary
Concomitant
Proteinuria Hospitalization 5/1/2009 83 6/17/2009 Physician Italy
Primary
Concomitant
General Physical Health Deterioration Hospitalization 6/11/2009 77 6/24/2009 Physician France
Primary
Concomitant
Gastrointestinal Stromal Tumour 4/21/2009 68 6/29/2009 Physician Turkey
Primary
Concomitant
Hyperglycaemia Other Serious 6/1/2008 64 7/1/2009 Physician Belgium
Primary
Concomitant
Proteinuria Hospitalization 5/1/2009 83 7/9/2009 Physician Italy
Primary
Concomitant
Infection Hospitalization 6/17/2009 49 7/10/2009 Physician Korea, Republic Of
Primary
Concomitant
Ascites Hospitalization 11/15/2007 42 7/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Proteinuria Hospitalization 5/20/2009 83 7/21/2009 Physician Italy
Primary
Concomitant
Sepsis Other Serious 4/13/2009 79 7/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 12/22/2008 69 7/28/2009 Physician Japan
Primary
Concomitant
Ascites Hospitalization 11/15/2007 42 7/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Disorder Other Serious 3/9/2009 59 7/29/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 3/16/2009 55 8/4/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 3/16/2009 55 8/17/2009 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 7/3/2009 82 8/17/2009 Physician Japan
Primary
Concomitant
Proteinuria Hospitalization 5/20/2009 83 8/18/2009 Physician Italy
Primary
Concomitant
Anxiety Other Serious 6/26/2009 70 8/24/2009 Other Health Professional Canada
Primary
Concomitant
Renal Cancer Metastatic Hospitalization 7/9/2009 58 8/26/2009 Physician United Kingdom
Primary
Concomitant
Hemiparesis Hospitalization 8/18/2009 50 8/31/2009 Physician India
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/9/2009 67 9/2/2009 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 4/29/2009 77 9/7/2009 Physician France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/17/2009 68 9/4/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/11/2009 72 9/10/2009 Physician Japan
Primary
Concomitant
Hemiparesis Hospitalization 8/18/2009 50 9/14/2009 Physician India
Primary
Concomitant
Thrombocytopenia Hospitalization 9/7/2009 57 9/17/2009 Physician Germany
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/11/2009 72 9/25/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/19/2007 40 9/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Melaena Hospitalization 9/18/2009 71 10/1/2009 Physician India
Primary
Concomitant
Melaena Hospitalization 9/18/2009 71 10/16/2009 Physician India
Primary
Concomitant
Cholecystitis Acute Hospitalization 8/21/2009 61 10/23/2009 Physician Japan
Primary
Concomitant
Death Death 10/1/2007 45 10/30/2009 Physician Turkey
Primary
Concomitant
Death Death 1/1/2009 58 Female 89 lb 11/2/2009 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 3/14/2007 50 Female 146 lb 11/3/2009 Other Health Professional Brazil
Primary
Concomitant
Nausea Hospitalization 9/7/2009 57 Male 185 lb 11/6/2009 Physician Germany
Primary
Concomitant
Malignant Pleural Effusion Hospitalization 8/17/2009 49 Female 207 lb 11/10/2009 Physician France
Primary
Concomitant
Respiratory Failure Hospitalization 3/14/2007 74 Male 146 lb 11/11/2009 Other Health Professional Brazil
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 7/10/2009 69 Male 251 lb 11/12/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 8/20/2009 61 Female 123 lb 11/16/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Hospitalization 2/12/2008 68 Female 106 lb 11/16/2009 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Vitreous Haemorrhage Other Serious 9/11/2009 69 Male 127 lb 11/17/2009 Physician Japan
Primary
Concomitant
Gastrointestinal Stromal Tumour Death 6/5/2009 58 Female 89 lb 11/16/2009 Physician Japan
Primary
Concomitant
Nausea Hospitalization 9/7/2009 57 Male 185 lb 11/23/2009 Physician Germany
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Other Serious 63 Male 157 lb 11/25/2009 Physician United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 11/3/2008 60 Male 203 lb 11/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/19/2007 40 Male 11/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 9/22/2009 67 Male 11/30/2009 Physician Japan
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 8/11/2009 57 Male 142 lb 12/3/2009 Physician Japan
Primary
Concomitant
Chest Pain Other Serious 63 Male 157 lb 12/3/2009 Physician United Kingdom
Primary
Concomitant
Proteinuria Other Serious 1/22/2008 39 Female 128 lb 12/4/2009 Physician Thailand
Primary
Concomitant
Renal Failure Hospitalization 11/11/2009 Male 12/11/2009 Physician Germany
Primary
Concomitant
Gastroduodenitis Hospitalization 11/16/2009 Female 212 lb 12/28/2009 Physician Argentina
Primary
Concomitant
Gastritis Erosive Hospitalization 12/12/2009 64 12/22/2009 Physician Argentina
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2008 80 Male 152 lb 1/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Angina Pectoris Other Serious 63 Male 157 lb 1/11/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/9/2009 Male 1/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vitreous Haemorrhage Other Serious 9/3/2009 69 Male 127 lb 1/19/2010 Physician Japan
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/20/2009 Male 171 lb 1/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/11/2009 Male 1/18/2010 Physician Germany
Primary
Concomitant
Metastases To Central Nervous System Death 8/20/2009 67 Male 136 lb 1/22/2010 Physician Japan
Primary
Concomitant
Gastritis Erosive Hospitalization 12/9/2009 64 Female 212 lb 1/22/2010 Physician Argentina
Primary
Concomitant
Thrombocytopenia Hospitalization 11/27/2009 Female 179 lb 2/1/2010 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 1/13/2010 80 Male 2/3/2010 Physician Germany
Primary
Concomitant
Pleural Effusion Hospitalization 8/1/2008 80 Male 152 lb 2/3/2010 Physician United Kingdom
Primary
Concomitant
Death Death 12/20/2009 Male 171 lb 2/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 11/11/2009 78 Male 2/12/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Disorder Other Serious 3/9/2009 59 Male 111 lb 2/15/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 1/13/2010 80 Male 2/15/2010 Physician Germany
Primary
Concomitant
Pneumonia Bacterial Life Threatening 8/24/2009 66 Male 153 lb 2/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2009 49 Female 137 lb 2/15/2010 Physician Japan
Primary
Concomitant
Renal Disorder 3/9/2009 59 Male 111 lb 2/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2009 49 Female 137 lb 2/24/2010 Physician Japan
Primary
Concomitant
Death Other Serious 11/16/2009 50 Male 128 lb 2/24/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 7/20/2009 61 Female 116 lb 3/1/2010 Physician Japan
Primary
Concomitant
Pneumonia Life Threatening 12/16/2008 50 Female 137 lb 3/2/2010 Physician Japan
Primary
Concomitant
Diabetes Mellitus Hospitalization 11/11/2009 Male 3/5/2010 Consumer United States
Primary
Secondary
Concomitant
Diabetes Mellitus Hospitalization 11/11/2009 78 Male 3/10/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Nausea Hospitalization 9/7/2009 57 Male 185 lb 3/11/2010 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/7/2009 49 Female 137 lb 3/12/2010 Physician Japan
Primary
Concomitant
Pharyngeal Haemorrhage Other Serious 10/2/2009 59 Male 118 lb 3/12/2010 Physician Japan
Primary
Concomitant
Waist Circumference Increased Hospitalization 11/11/2009 Male 3/15/2010 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/13/2010 80 Male 3/18/2010 Physician Germany
Primary
Concomitant
Vertigo Other Serious 7/30/2007 77 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 2/1/2010 59 Male 170 lb 3/26/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 9/14/2009 72 Male 146 lb 3/30/2010 Physician Japan
Primary
Concomitant
Nausea Hospitalization 9/7/2009 57 Male 185 lb 3/31/2010 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 11/6/2006 73 Male 212 lb 4/1/2010 Physician Argentina
Primary
Concomitant
Death Death 12/7/2009 82 Male 115 lb 4/9/2010 Physician Japan
Primary
Concomitant
Hypothyroidism Other Serious 7/29/2009 53 Female 88 lb 4/9/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 7/19/2007 40 Male 4/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 11/24/2009 36 Female 140 lb 4/15/2010 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 9/15/2008 74 Female 157 lb 4/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 8/24/2008 74 Female 157 lb 4/27/2010 Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/11/2009 66 Male 4/27/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Thrombosis Other Serious 11/22/2009 36 Female 140 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Metastatic Death 12/20/2009 66 Male 171 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroiditis Other Serious 57 Female 132 lb 5/5/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 3/18/2008 65 Female 5/4/2010 Physician
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/2/2006 70 Male 205 lb 5/11/2010 Physician Poland
Primary
Concomitant
Hypoacusis Hospitalization 2/7/2006 66 Male 5/21/2010 Other Health Professional Belgium
Primary
Concomitant
Myocardial Infarction Hospitalization 8/23/2008 79 Male 174 lb 5/26/2010 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2010 65 Male 6/1/2010 Physician Japan
Primary
Concomitant
Pneumothorax Life Threatening 2/17/2010 72 Male 6/1/2010 Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 8/14/2006 38 Male 132 lb 6/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Sepsis Death 1/25/2007 73 Female 106 lb 6/3/2010 Physician Korea, Republic Of
Primary
Concomitant
Anal Abscess Hospitalization 12/27/2009 62 Male 6/8/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/27/2008 78 Female 117 lb 6/18/2010 Physician Germany
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Other Serious 2/16/2010 71 Male 6/21/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/24/2010 85 Female 156 lb 6/21/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/8/2009 72 Female 335 lb 6/28/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 7/24/2008 72 Male 198 lb 7/1/2010 Germany
Primary
Secondary
Concomitant

Drug Data