Amlodipine combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vascular Bypass Graft Hospitalization 2/2/2005 76 Male 172 lb 1/3/2006 Czech Republic
Primary
Secondary
Concomitant
Superinfection Lung Hospitalization 1/1/2005 81 Female 132 lb 1/13/2006 Physician France
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/10/2006 58 Male 1/30/2006 Physician United States
Primary
Concomitant
Ventricular Failure Required Intervention 12/1/2005 Female 2/8/2006 Physician Netherlands
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 2/5/2006 Female 3/29/2006 Pharmacist
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1 Female 4/1/2006 Other Health Professional Canada
Primary
Secondary
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Ventricular Hypertrophy Other Serious 1 Female 4/10/2006 Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 11/22/2005 71 Male 194 lb 5/9/2006 Physician Belgium
Primary
Concomitant
Rash Maculo-papular Required Intervention 9/24/2005 76 Female 159 lb United States
Primary
Concomitant
Somnolence Hospitalization 12/1/2004 84 Female 5/15/2006 Physician Chile
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious Female 6/9/2006
Primary
Secondary
Viral Myositis Hospitalization 5/5/2006 68 Male 6/8/2006 Other Health Professional South Africa
Primary
Concomitant
Postoperative Infection Hospitalization 89 Female 7/7/2006 Physician United States
Primary
Secondary
Postoperative Infection Hospitalization 89 Female 7/11/2006 Physician United States
Primary
Secondary
Respiratory Failure Hospitalization 10/31/2005 45 Female 7/28/2006 Physician Germany
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 6/15/2000 67 Male 8/15/2006 France
Primary
Concomitant
Haemoptysis Other Serious 6/9/2006 78 Male 170 lb 8/23/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Other Serious Female 9/6/2006 Canada
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 137 lb 9/15/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Staphylococcal Infection Hospitalization 8/19/2006 28 Female 137 lb 9/22/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 9/25/2006 Consumer United States
Primary
Concomitant
Circulatory Collapse Death 69 Male 9/30/2006 Physician Singapore
Primary
Secondary
Rash Pruritic 9/12/2006 46 Male 193 lb 9/19/2006 United States
Primary
Concomitant
Linear Iga Disease Other Serious 73 Male 10/26/2006 Physician United States
Primary
Concomitant
Myocardial Ischaemia Death 69 Male 11/14/2006 Physician Singapore
Primary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Other Serious 6/30/2006 63 Male 121 lb 12/18/2006 Physician Japan
Primary
Secondary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 1/1/2006 36 Female 216 lb 10/24/2006 United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Blood Urea Increased Life Threatening 12/19/2006 52 Male 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 58 Female 280 lb 1/25/2007 Other Health Professional Poland
Primary
Concomitant
Renal Injury Disability 9/1/2006 83 Female 3/1/2007
Primary
Concomitant
Pneumonia Hospitalization 8/19/2006 28 Female 115 lb 3/5/2007 Consumer United States
Primary
Concomitant
Renal Failure Disability 9/1/2006 83 Female 2/26/2007 United Kingdom
Primary
Concomitant
Palpitations 37 Female 224 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 1/1/2005 80 Female 182 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Breast Cancer Hospitalization 2/23/2007 68 Female 251 lb 5/2/2007 Physician United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 6/9/2006 78 Male 170 lb 5/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoptysis Other Serious 6/9/2006 78 Male 5/2/2007 United Kingdom
Primary
Concomitant
Amnesia Other Serious Male 220 lb 5/31/2007 Physician United States
Primary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/8/2007 71 Male 142 lb 6/28/2007 Physician United Kingdom
Primary
Concomitant
Thrombosis In Device Hospitalization 67 Male 7/3/2007 United States
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 67 Male 7/2/2007 United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 7/6/2007 United Kingdom
Primary
Secondary
Concomitant
Death Hospitalization 57 Female 8/20/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 58 Male 8/24/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 54 Male 8/24/2007 United States
Primary
Secondary
Guillain-barre Syndrome Other Serious 58 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 2/2/2005 76 Male 172 lb 8/28/2007 Czech Republic
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 57 Female 263 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Failure Other Serious 1/1/2002 58 Male 9/28/2007 United Kingdom
Primary
Concomitant
Interacting
Pollakiuria Other Serious 7/16/2007 69 Male 10/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 57 Female 263 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Hospitalization 8/7/2007 57 Male 257 lb 10/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/1/2007 69 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 6/10/2007 Male 200 lb 11/21/2007 United States
Primary
Concomitant
Bone Marrow Failure Other Serious 5/1/2007 43 Male 209 lb 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Haemoconcentration Other Serious 8/16/2007 60 Male 11/16/2007 Russian Federation
Primary
Secondary
Drug Hypersensitivity Hospitalization 58 Female 12/12/2007 France
Primary
Concomitant
Visual Acuity Reduced Other Serious 3/1/2007 85 Male 12/17/2007 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Renal Disorder Hospitalization 12/4/2007 76 Female 12/21/2007 Australia
Primary
Concomitant
Renal Impairment Hospitalization 12/4/2007 76 Female 1/7/2008 Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 1/17/2008 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/13/2004 77 Male 1/29/2008 Physician Germany
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/4/2007 76 Female 1/30/2008 Australia
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/5/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 Male 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/19/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/21/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/22/2008 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/13/2004 78 Male 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/25/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 81 Male 2/29/2008 Other Health Professional Germany
Primary
Secondary
Hypotension Other Serious 54 Male 3/10/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 2/6/2008 76 Male 195 lb 3/7/2008 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 12/4/2007 76 Female 3/21/2008 Australia
Primary
Concomitant
Muscular Weakness Other Serious 4/15/2008 84 Male 194 lb 4/18/2008 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 12/4/2007 Female 4/30/2008 Australia
Primary
Concomitant
Renal Impairment Other Serious 12/4/2007 Female 5/8/2008 Australia
Primary
Concomitant
Transfusion Reaction Other Serious 54 Male 5/14/2008 United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious 2/9/2008 58 Female 5/14/2008 Physician United Kingdom
Primary
Concomitant
Transfusion Reaction Other Serious 54 Male 5/20/2008 Physician United States
Primary
Concomitant
Transfusion Reaction Other Serious 54 Male 5/29/2008 United States
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 4/21/2008 Male 203 lb 5/30/2008 Romania
Primary
Concomitant
Fall Disability 5/7/2008 75 Female 142 lb 5/23/2008 Consumer United States
Primary
Concomitant
Renal Failure 4/28/2008 Female 71 lb 6/3/2008 Physician Japan
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 6/12/2008 Consumer United States
Primary
Concomitant
Leucine Aminopeptidase Decreased Life Threatening 54 Male 6/16/2008 Other Health Professional United States
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/11/2008 United Kingdom
Primary
Concomitant
Uterine Cervix Stenosis Other Serious 11/1/2007 60 Female 6/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 4/22/2008 Male 6/27/2008 Netherlands
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Pruritus Generalised 75 Male 7/1/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 4/21/2008 67 Male 153 lb 6/28/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 138 lb 7/7/2008 Physician
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 138 lb 8/18/2008 Physician
Primary
Concomitant
Renal Impairment Other Serious 12/4/2007 Female 8/20/2008 Australia
Primary
Concomitant
Procedural Hypotension Required Intervention 54 Male 5/22/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/1/2007 Male 8/27/2008 Canada
Primary
Concomitant
Palpitations 6/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Syncope Other Serious 84 Female 8/27/2008 Physician United States
Primary
Secondary
Rhabdomyolysis Other Serious 74 Male 9/4/2008 United Kingdom
Primary
Secondary
Concomitant
Interacting
Weight Decreased Other Serious 1/1/2007 Female 138 lb 9/8/2008 Physician
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/12/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2007 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 10/19/2007 65 Female 240 lb 10/7/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 74 Male 10/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 1 Male 35 lb 10/13/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Hydrocele Other Serious 1/1/2008 Male 241 lb 11/20/2008 Physician United States
Primary
Secondary
Concomitant
Ulcer 1/1/2006 Female 126 lb 11/25/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 11/21/2008 66 Male 12/1/2008 Other Health Professional Turkey
Primary
Secondary
Concomitant
Death Death 11/22/2007 Male 185 lb 12/1/2008 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 59 Female 11/26/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Life Threatening 10/1/2008 65 Female 12/9/2008 Physician Austria
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2008 80 Female 215 lb 11/19/2008 Pharmacist United States
Primary
Concomitant
Hernia Other Serious 9/1/2008 Male 189 lb 12/19/2008 Consumer United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 10/9/2008 Female 237 lb 12/23/2008 Consumer United States
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 12/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Thrombocytopenia Hospitalization 1 Male 12/22/2008 Other Health Professional Canada
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 1/5/2009 Consumer Portugal
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Renal Failure Acute Hospitalization 59 Female 216 lb 1/12/2009
Primary
Secondary
Concomitant
Dyspnoea Other Serious 9/9/2008 Female 237 lb 1/15/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Sensory Loss Other Serious 58 Male 1/18/2009 United Kingdom
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/1/2007 Male 172 lb 1/26/2009 Physician Germany
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Oedema 5/1/2008 Female 99 lb 2/5/2009 Physician United States
Primary
Concomitant
Chest Discomfort Hospitalization 11/15/2008 61 Male 305 lb 2/5/2009 Sweden
Primary
Concomitant
Cholecystitis Acute Hospitalization 7/10/2008 70 Male 2/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/8/2008 71 Male 181 lb 2/12/2009 Physician Germany
Primary
Concomitant
Skin Exfoliation Disability 1/12/2009 Male 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pleural Effusion Other Serious 12/8/2008 71 Male 181 lb 2/23/2009 Physician Germany
Primary
Concomitant
Nephrogenic Systemic Fibrosis Disability 1/1/2002 55 Male 190 lb 3/4/2009 Belgium
Primary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/12/2009 Other Health Professional Sweden
Primary
Concomitant
Renal Failure Hospitalization 11/15/2008 61 Male 305 lb 3/17/2009 Sweden
Primary
Concomitant
Renal Failure Acute Life Threatening 8/5/2008 78 Female 176 lb 3/18/2009 Physician Germany
Primary
Secondary
Concomitant

Drug Data