Amlodipine combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Metabolic Acidosis Life Threatening 7 Male 29 lb 3/13/2006 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 53 Female 4/13/2006 United States
Primary
Concomitant
Hyperammonaemia Required Intervention 79 Male 8/29/2005 Other Health Professional United States
Primary
Concomitant
Skin Oedema Hospitalization 76 Male 9/21/2006 Physician United Kingdom
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 4/10/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 1/15/2007 83 Male 154 lb 5/11/2007 Physician United States
Primary
Concomitant
Hepatitis Hospitalization 2/19/2007 72 Male 5/16/2007 United Kingdom
Primary
Secondary
Concomitant
Vasculitis Life Threatening 32 Male 8/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 1/10/2007 82 Male 217 lb 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 32 Male 9/11/2007 United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 9/9/2007 48 Male 118 lb 9/10/2007 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Life Threatening 32 Male 9/28/2007 United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 56 Male 9/28/2007 Germany
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 4 Female 10/10/2007
Primary
Secondary
Concomitant
Pituitary Tumour Benign Hospitalization 6/8/2007 Male 221 lb 10/4/2007 Physician Belgium
Primary
Concomitant
Vomiting Other Serious 8/1/2007 Female 129 lb 10/23/2007 Consumer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 56 Male 12/26/2007
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 42 Male 12/20/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 56 Male 12/31/2007 India
Primary
Concomitant
Interacting
Pituitary Tumour Benign Hospitalization 6/8/2007 Male 221 lb 12/24/2007 Physician Belgium
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 1/25/2008 Physician Germany
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Required Intervention 3/13/2007 70 Female 1/24/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 66 Female 2/13/2008 United Kingdom
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Life Threatening 10/24/2004 Female 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 10/27/2004 76 Female 2/29/2008 Physician Germany
Primary
Secondary
Concomitant
Death Death 1/1/2008 66 Female 132 lb 2/29/2008 Physician Malaysia
Primary
Concomitant
Thrombocytopenia Required Intervention 66 Female 4/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Drug Level Decreased Life Threatening 4/1/2008 61 Male 170 lb 4/9/2008 Pharmacist United States
Primary
Concomitant
Transaminases Increased Hospitalization 9/3/2007 72 Female 5/16/2008 Other Health Professional Singapore
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 2/6/2008 9 Female 82 lb 5/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Status Epilepticus Hospitalization 5/10/2008 Male 176 lb 7/2/2008 Physician Switzerland
Primary
Concomitant
Status Epilepticus Hospitalization 5/10/2008 Male 176 lb 7/14/2008 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 8/13/2008 Other Health Professional Brazil
Primary
Concomitant
Rash 1/1/2006 Female 90 lb 8/22/2008 Consumer United States
Primary
Concomitant
Melaena Life Threatening 9/8/2008 50 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 10/10/2008 Other Health Professional Brazil
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 7/22/2007 Male 97 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Status Epilepticus Required Intervention 3/13/2007 70 Female 11/7/2008 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious Male 248 lb 11/18/2008 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 69 Male 12/29/2008 Pharmacist United States
Primary
Secondary
Completed Suicide Death 69 Male 12/31/2008 Physician United States
Primary
Secondary
Concomitant
Convulsion Other Serious Male 248 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Medication Error Death 89 Female 1/14/2009 Physician United States
Primary
Secondary
Completed Suicide Death 69 Male 1/15/2009 Physician United States
Primary
Secondary
Poisoning Death 69 Male 1/19/2009 Physician United States
Primary
Secondary
Drug Abuse Death 69 Male 1/26/2009
Primary
Secondary
Intentional Overdose Death 69 Male 1/27/2009 Physician United States
Primary
Secondary
Poisoning Deliberate Death 69 Male 1/16/2009 Physician United States
Primary
Secondary
Completed Suicide Death 69 Male 1/21/2009 Physician United States
Primary
Secondary
Completed Suicide Death 69 Male 1/30/2009 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 1/1/2007 69 Male 1/20/2009 Physician United States
Primary
Secondary
Treatment Noncompliance Other Serious Male 248 lb 2/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Angioedema Hospitalization 1/22/2009 2/27/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Completed Suicide Death 69 Male 3/24/2009 Other Health Professional United States
Primary
Secondary
Intentional Overdose Death 69 Male 3/25/2009 Consumer United States
Primary
Secondary
Drug Abuse Death 69 Male 3/25/2009 Consumer United States
Primary
Secondary
Intentional Overdose Death 69 Male 3/26/2009 Consumer United States
Primary
Secondary
Drug Abuse Death 69 Male 3/26/2009 Consumer United States
Primary
Secondary
Drug Abuse Death 69 Male 3/30/2009 Consumer United States
Primary
Secondary
Intentional Overdose Death 69 Male 3/30/2009 Consumer United States
Primary
Secondary
Thrombocytopenia Other Serious 12/10/2008 Male 121 lb 4/27/2009 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 7/9/2009 81 Female 210 lb 7/31/2009 Consumer United States
Primary
Concomitant
Tumour Haemorrhage Other Serious 4/15/2007 71 Male 115 lb 8/28/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 3/1/2007 32 Female 121 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 7/22/2009 50 Female 9/25/2009 United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/1/2008 33 Female 121 lb 10/6/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2006 66 Female 12/19/2009 Physician United States
Primary
Concomitant
Overdose Death 72 Male 1/21/2010 Physician United States
Primary
Secondary
Completed Suicide Death 72 Male 1/25/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 72 Male 2/1/2010 Physician United States
Primary
Secondary
Poisoning Death 1/1/2008 72 Male 2/1/2010 Physician United States
Primary
Secondary
Drug Abuse Death 72 Male 2/22/2010
Primary
Secondary
Troponin Increased 4/13/2009 72 Male 160 lb 4/21/2009 Pharmacist United States
Primary
Concomitant
Completed Suicide Death 3/4/2010 Physician United States
Primary
Secondary
Neutropenia Hospitalization 1/1/2009 Male 3/4/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Other Serious 9/1/2007 45 Male 152 lb 3/18/2010 Lawyer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2007 60 Male 3/18/2010 Other Health Professional United States
Primary
Concomitant
Dizziness 2/2/2010 70 Female 4/12/2010 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 4/15/2010 Consumer United States
Primary
Concomitant
Diabetic Complication Death 90 Female 5/3/2010 Consumer United States
Primary
Concomitant
Hyponatraemia Hospitalization 3/20/2010 85 Female 139 lb 5/20/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/1/2008 33 Female 121 lb 5/24/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 2/19/2010 28 Female 119 lb 6/14/2010 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/1/2007 60 Male 6/15/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 9/1/2007 43 Male 152 lb 6/17/2010 Other Health Professional United States
Primary
Concomitant
Convulsion Life Threatening 5/13/2010 72 Female 155 lb 6/22/2010 Physician United Kingdom
Primary
Concomitant
Thrombosis Other Serious 2/19/2010 27 Female 112 lb 7/1/2010 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 1/3/2008 76 Male 7/7/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 8/1/2008 45 Female 163 lb 8/3/2010 Lawyer United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 80 Female 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 80 Female 9/13/2010
Primary
Secondary
Treatment Noncompliance Other Serious 11/1/2007 60 Male 9/30/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 8/1/2008 45 Female 163 lb 9/30/2010 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 9/1/2007 43 Male 152 lb 11/8/2010 Lawyer United States
Primary
Concomitant
Respiratory Alkalosis Hospitalization 60 Male 201 lb 12/13/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Alkalosis Hospitalization 60 Male 201 lb 12/13/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Alkalosis Hospitalization 60 Male 201 lb 12/13/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Respiratory Alkalosis Other Serious 2/22/2009 60 Male 200 lb 12/9/2010 Physician Italy
Primary
Secondary
Concomitant
Otitis Media Hospitalization 9/1/2007 43 Male 152 lb 1/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Injection Site Haematoma Hospitalization 10/26/2010 67 Female 2/1/2011 Pharmacist United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2010 61 Female 4/15/2011 Brazil
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 44 Female 4/18/2011 Physician United States
Primary
Concomitant
Hyperaemia Hospitalization 1/1/2010 61 Female 4/6/2011 Brazil
Primary
Secondary
Concomitant
Depression Other Serious 11/13/2002 55 Male 119 lb 5/31/2011 Other Health Professional United States
Primary
Concomitant
Pruritus Other Serious 1/1/2003 31 Female 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 1/1/2007 69 Male 7/11/2011 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 69 Male 7/11/2011 Physician United States
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Hospitalization 2/22/2009 60 Male 7/21/2011 Other Health Professional Italy
Primary
Secondary
Intentional Drug Misuse Death 1/1/2008 72 Male 7/21/2011 Physician United States
Primary
Secondary
Psychotic Disorder Death 48 7/28/2011 Other Health Professional Denmark
Primary
Secondary
Decreased Appetite Other Serious 8/1/2011 54 Male 192 lb 8/25/2011 Consumer Brazil
Primary
Concomitant
Death Death 48 8/26/2011 Physician Denmark
Primary
Secondary
Abdominal Pain Disability 6/1/2011 54 Male 192 lb 9/1/2011 Physician Brazil
Primary
Concomitant
Mental Status Changes Hospitalization 65 Male 9/8/2011 Other Health Professional United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 65 Male 9/9/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram St-t Change Hospitalization 6/29/2011 84 Female 130 lb 9/14/2011 Pharmacist United States
Primary
Concomitant
Malaise Other Serious 8/1/2011 132 lb 9/21/2011 Physician United Kingdom
Primary
Concomitant
Dry Skin Other Serious 1/1/2003 31 Female 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 65 Male 9/21/2011 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/1/2009 81 Female 9/27/2011 Other Health Professional United States
Primary
Concomitant
Decreased Appetite Disability 1/1/2011 54 Male 192 lb 9/29/2011 Consumer Brazil
Primary
Concomitant
Speech Disorder Hospitalization 65 Male 9/23/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Other Serious 1/1/2003 31 Female 132 lb 10/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 9/19/2011 66 Male 150 lb 10/10/2011 Physician Greece
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/19/2011 66 Male 150 lb 10/14/2011 Physician Greece
Primary
Secondary
Concomitant
Sepsis Death 86 Female 10/19/2011 Physician India
Primary
Concomitant
Transaminases Increased Hospitalization 9/19/2011 66 Male 150 lb 10/20/2011 Physician Greece
Primary
Secondary
Concomitant
Encephalopathy Disability 1/1/2011 54 Male 192 lb 10/24/2011 Physician Brazil
Primary
Concomitant
Leukocytosis Life Threatening 44 Female 10/18/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Other Serious 73 Male 11/9/2011 Other Health Professional Germany
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/1/2009 81 Female 11/9/2011 Other Health Professional United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Life Threatening 86 Female 11/8/2011 Other Health Professional India
Primary
Concomitant
Rash Papular Hospitalization 65 Male 11/21/2011 United States
Primary
Concomitant
Drug Ineffective Hospitalization 1/1/2010 61 Female 12/15/2011 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 58 Male 12/20/2011 Physician United States
Primary
Secondary
Dysphagia Hospitalization Male 12/27/2011 Pharmacist United Kingdom
Primary
Concomitant
Hellp Syndrome Other Serious 41 Female 161 lb 12/20/2011 Other Health Professional India
Primary
Secondary
Dysphagia Disability Male 12/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2010 61 Female 12/20/2011
Primary
Secondary
Concomitant
Unresponsive To Stimuli Disability Male 12/29/2011 Pharmacist United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2010 61 Female 12/29/2011 Consumer United States
Primary
Secondary
Concomitant
Communication Disorder Disability Male 1/2/2012 Other Health Professional United Kingdom
Primary
Concomitant
Dysphagia Disability Male 1/3/2012 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Peripheral Hospitalization 1/1/2010 61 Female 12/30/2011
Primary
Secondary
Concomitant
Dysphonia Disability Male 12/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Poisoning Death 1/1/2010 58 Male 1/10/2012 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2010 58 Male 1/9/2012 Physician United States
Primary
Secondary

Drug Data